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Table 1 Demographic and clinical characteristics of the studied RPGN patients

From: Clinicopathological characteristics and predictors of outcome of rapidly progressive glomerulonephritis: a retrospective study

Variables

Type I RPGN

n = 20

Type II RPGN

n = 48

Type III RPGN

n = 33

I vs. II

I vs. III

II vs. III

P value

Age (years)

34 (13)

29 (10.75)

60 (10)

   

25–44

20–55

45–68

0.54

< 0.001

< 0.001

Gender (%)

      

 Male

 Female

6 (30%)

14 (70%)

14 (29.2%)

34 (70.8%)

23 (69.7%)

10 (30.3%)

0.92

< 0.001

< 0.001

BMI (Kg/m2)

26.5 (1.95)

24.3–29.4

26.4 (2.1)

22.65–29.7

25.8 (3.3)

22–31.64

0.7

0.25

0.37

HTN (%)

14 (70%)

40 (83.3%)

15 (45.5%)

0.21

0.08

< 0.001

Edema (%)

6 (30%)

30 (62.5%)

19 (57.6%)

0.01

0.051

0.65

Microscopic hematuria (%)

10 (50%)

40 (83.3%)

28 (84.8%)

0.004

0.006

0.85

Macroscopic hematuria (%)

10 (50%)

8 (16.7%)

5 (15.2%)

0.004

0.006

0.85

Oliguria (%)

12 (60%)

30 (62.5%)

13 (39.4%)

0.84

0.14

0.04

Fever (%)

2 (10%)

18 (37.5%)

2 (6.1%)

0.02

0.59

< 0.001

Skin rash (%)

2 (10%)

30 (62.5%)

2 (6.1%)

< 0.001

0.6

< 0.001

Hemoptysis (%)

14 (70%)

8 (16.7%)

8 (24.2%)

< 0.001

0.001

0.22

Arthritis (%)

4 (20%)

30 (62.5%)

12 (36.4%)

0.001

0.2

0.02

Need for HD at presentation (%)

14 (70%)

30 (62.5%)

11 (33.3%)

0.4

< 0.001

< 0.001

Serum creatinine at presentation (mg/dL)

5.25 (4)

4.75 (3.65)

2.7 (2.6)

   

2.3–7.2

1.8–8.0

1.2–5.8

0.43

0.003

0.048

GFR at presentation (ml/min/1.732)

10.5 (10)

12.5 (18.75)

20 (14)

   

7–28

6–45

9–81

0.45

0.003

0.052

Hb (gm/dL)

8.3 (1.6)

8.85 (1.35)

8.9 (2)

   

7.6–10.5

6.9–10

6.6–10.2

0.45

0.97

0.6

Serum albumin (gm/dL)

3 (0.2)

2.1 (1.0)

1.9 (0.4)

   

2.7–3.1

1.6–3.1

1.8–2.6

< 0.001

< 0.001

0.04

Proteinuria (gm/day)

2.8 (0.8)

5.1 (2.1)

4.8 (1.15)

   
 

2–3.4

3.5–12

3.5–6.8

< 0.001

< 0.001

0.54

  1. BMI: body mass index, eGFR: estimated glomerular filtration rate, Hb: hemoglobin, HD: hemodialysis, RPGN: rapidly progressive glomerulonephritis
  2. Data were expressed as number (%),or median (Interquartile range) and minimum-maximum