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Table 8 Cox regression study to determine predictors of mortality in the patients

From: Clinicopathological characteristics and predictors of outcome of rapidly progressive glomerulonephritis: a retrospective study

Variables

Univariate Cox regression

Multivariate Cox regression

P value

HR

95% CI

P value

HR

95% CI

Lower

Upper

Lower

Upper

Hemoptysis

< 0.001

0.11

0.05

0.23

0.13

0.37

0.10

1.32

Infections

< 0.001

0.08

0.03

0.23

0.02

0.17

0.04

0.79

Respiratory failure

< 0.001

0.08

0.04

0.17

< 0.001

0.03

0.01

0.15

Heart failure

< 0.001

0.17

0.07

0.37

0.004

0.20

0.07

0.59

IFTA (moderate - severe)

< 0.001

0.2

0.08

0.49

0.76

1.27

0.27

5.99

Fibrous crescents

< 0.001

1.83

1.49

2.25

0.94

0.99

0.65

1.48

TLO formation

0.001

0.27

0.12

0.59

0.6

1.28

0.51

3.21

Sclerotic glomeruli

< 0.001

1.43

1.24

1.66

0.45

1.14

0.81

1.62

Need for HD

0.002

0.27

0.11

0.62

0.29

2.23

0.50

9.90

eGFR at biopsy

0.14

0.98

0.95

1.01

0.02

0.97

0.945

1.00

  1. HR: hazard ratio, HD: hemodialysis, IFTA: interstitial fibrosis and tubular atrophy, TLO: tertiary lymphoid organ, eGFR: estimated glomerular filtration rate, CI: confidence interval