From: Dotinurad restores exacerbated kidney dysfunction in hyperuricemic patients with chronic kidney disease
Baseline
After 3 M
p-value
Mean
SD
Serum creatinine, mg/dL
1.90
0.87
1.73
0.82
< 0.001
Serum uric acid, mg/dL
8.1
1.7
6.7
0.99
Urinary protein, g/gCr
1.1
1.2
0.2
Fractional excretion of uric acid, %
7.56
4.68
7.35
3.56
0.8