Table 1 Patient characteristics

Age (years)

69 [56; 79]

69 [55; 76]

69 [56; 81]

0.098

Sex (male) n, (%)

218 (66.5)

117 (68.4)

101 (64.3)

0.433

High (cm)

173 [166; 180]

174 [165; 180]

173 [167; 178]

0.584

Weight (kg)

80 [69; 92]

80 [70; 94]

77 [68; 90]

0.086

BMI (kg/m²)

26.23 [23.2; 30.0]

26.6 [23.2; 30.7]

25.5 [23.2; 28.7]

0.143

Mechanical ventilation n, (%)

116 (35.4)

82 (48.0)

34 (21.7)

< 0.001

Sepsis n, (%)

112 (34.1)

77 (45.0)

35 (22.3)

< 0.001

Vasopressors n, (%)

135 (41.2)

101 (59.1)

34 (21.7)

< 0.001

AKI 3 n, (%)

119 (36.3)

97 (56.7)

22 (14.0)

< 0.001

SOFA n, (%)

7 [3; 12]

11 [7; 14]

4 [2; 7]

< 0.001

APACHE II

27 [19; 33]

32 [26; 38]

21 [16; 28]

< 0.001

MAP (mmHg)

86 [69; 103]

81 [63; 96]

94 [75; 110]

< 0.001

HR (bpm)

96 [81; 111]

101 [84; 119]

89 [79; 105]

< 0.001

Preexisting condition:

 Chronic heart failure (NYHA IV) n, (%)

5 (1.5)

3 (1.8)

2 (1.3)

0.723

 Pre-existing immunosuppression n, (%)

19 (5.8)

13 (7.6)

6 (3.8)

0.143

 Liver cirrhosis n, (%)

20 (6.1)

12 (7.0)

8 (5.1)

0.467

 Active malignancy n, (%)

17 (5.2)

14 (8.2)

3 (1.9)

0.010

 Chronic pulmonary disease n, (%)

44 (13.4)

23 (13.5)

21 (13.4)

0.984

 ^aeGFR < 45 ml/min/1.73m² n, (%)

44/79^a (55.7)

24/38^a (63.2)

20/41^a (48.8)

0.199

Causes of rhabdomyolysis:

 Infection n, (%)

43 (13.1)

28 (16.4)

15 (9.6)

0.068

 Muscle hypoxia n, (%)

176 (53.7)

78 (45.6)

98 (62.4)

0.002

 Drugs and toxins n, (%)

16 (4.9)

9 (5.3)

7 (4.5)

0.735

 Shock and post CPR n, (%)

34 (10.4)

27 (15.8)

7 (4.5)

< 0.001

 Metabolic/electrolyte disorders n, (%)

3 (0.9)

0

3 (1.9)

0.069

 Exertion n, (%)

5 (1.5)

3 (1.8)

2 (1.3)

0.723

 Electrical current n, (%)

19 (5.8)

10 (5.8)

9 (5.7)

0.964

 Other n, (%)

32 (9.8)

16 (9.4)

16 (10.2)

0.806