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Fig. 2 | BMC Nephrology

Fig. 2

From: Circular RNA hsa_circ_0005519 contributes to acute kidney injury via sponging microRNA-98-5p

Fig. 2

Elevated serum hsa_circ_0005519 was associated with cell viability. (A) Reverse transcription-qPCR analysis of expression of hsa_circ_0005519 in an in vitro model of AKI, LPS-induced HK-2 cells. ***p < 0.001. (B) Reverse transcription-qPCR analysis of hsa_circ_0005519 expression in transfected or non-transfected HK-2 cells. **p < 0.01, ***p < 0.001. (C) Reverse transcription-qPCR analysis of SNX13 (hsa_circ_0005519 host gene) expression in transfected or non-transfected HK-2 cells. (D) Inhibited hsa_circ_0005519 expression resulted in a decrease in HK-2 cell viability compared with siRNA negative control. Statistical analysis was completed using one-way ANOVA with post-hoc analysis of Turkey. ***p < 0.001, vs. blank. ##p < 0.01,vs. LPS + anti-NC

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