Fig. 6
From: Circular RNA hsa_circ_0005519 contributes to acute kidney injury via sponging microRNA-98-5p
Prediction of miR-98-5p-targeting genes. (A) Screening of AKI-related genes targeted by miR-98-5p. (B) The Gene Ontology (GO) enrichment analysis of the 61 obtained genes. (C) The Kyoto Encyclopedia of Genes, and Genomes (KEGG) pathways enrichment analysis of the 61 obtained genes. (D) Protein-protein interaction for the 61 obtained genes. (E) The binding sites of miR-98-5p in IGF1R and luciferase reporter analysis. (F) Reverse transcription-qPCR for IGF1R mRNA expression. (G) Western blots reulats for IGF1R protein expression. Statistical analysis was completed using one-way ANOVA with post-hoc analysis of Turkey. ***p < 0.001. ###p < 0.001,vs. control