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Table 2 Treatment patterns among pediatric patients across select countries/regions

From: Review on epidemiology, disease burden, and treatment patterns of IgA nephropathy in select APAC countries

Author year

Cohort age a

Sample size

ACEI/ARBs (%)

Other therapies (%)

Mainland China

Zhao 2021 [41]

8.4 ± 3.2

79

2.5

Steroid + immunosuppressant (72.2), steroid (25.3)

Wu 2020 [27]

13.7 ± 3.7

1243

70

Immunosuppressant (64), steroid (45), steroid + immunosuppressant (19)

WGNSSDTCRD [11]

10 (NR)

1417

49.5

Oral prednisone (47.5), intravenous methylprednisolone (21.8), CTX (19.6%), tripterygium wilfordii (15.2), MMF (6.3), leflunomide (1.7%), tonsillectomy (0.3)

Japan

Matsuzaki 2013 [54]

NR

92

95.7

Antiplatelet agents (82.6), tonsillectomy + steroid (38), intravenous steroid (33.2%), oral steroid (30.4)

Yata 2008 [49]

Children with DMP

10.9 (2.5–19.6) b

108

0.9

Immunosuppressant (68.5), steroid (23.1), antiplatelet agents (6.5%), no treatment (0.9)

Yata 2008 [49]

Children with FMP

10.9 (2.5–19.6) b

173

50.9

No treatment (13.2), steroid + immunosuppressant (4.6), steroid (3.5%), antiplatelet agents (1.2)

South Korea

Suh 2020 [73]

11.41 ± 3.9

1154

31.9

Immunosuppressant (50.2)

  1. Abbreviations: ACEI/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; CTX, cyclophosphamide; DMP, diffuse mesangial proliferation; FMP, focal mesangial proliferation; MMF, mycophenolate mofetil; WGNSSDTCRD, Working Group for National Survey on Status of Diagnosis and Treatment of Childhood Renal Diseases; NR, not reported
  2. (a) Data are expressed as mean ± SD or median (then interquartile range). (b) Baseline sample (n = 500)