Fig. 1

Expression and diagnostic potential of long non-coding ribonucleic acid (RNA) differentiation antagonizing non-protein coding RNA (DANCR) in diabetic nephropathy (DN). A. Serum DANCR was typically elevated in patients with diabetes mellitus without DN (DM) and DN, and more significantly in DN. B. Quantitative reverse transcription polymerase chain reaction was conducted to explore the DANCR levels in DN patients with micro-albuminuria or macro-albuminuria. C. Detected serum DANCR expression in high and low estimated glomerular filtration rate (eGFR) groups based on the mean eGFR values. The receiver operating characteristic curve was applied to analyze the diagnostic value of serum DANCR in differentiating DM from healthy volunteers (HVs) (D) and DN from DM (E). *** P < 0.001 vs. HV, micro-albuminuria, or low eGFR groups; ### P < 0.001 vs. DM group