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Table 3 Univariate and multivariate linear regression analyses of modifiable clinical variables in predicting estimated glomerular filtration rate in patients with recently diagnosed type 2 diabetes

From: Determinants of early chronic kidney disease in patients with recently diagnosed type 2 diabetes mellitus: a retrospective study from the Taiwan Diabetes Registry

 

Univariate analysis

P value

Multivariate analysis

P value

β (95% confident interval)

β (95% confident interval)

BW (per 10 kg)

1.720 (0.704, 2.736)

0.001

1.549 (0.498, 2.601)

0.004*

WC (per 10 cm)

-0.008 (-1.447, 1.431)

0.991

-

 

Systolic BP (per 10 mmHg)

-1.527 (-2.464, -0.591)

0.001

-1.423 (-2.395, -0.451)

0.004*

Diastolic BP (per 10 mmHg)

1.154 (-0.233, 2.541)

0.103

-

 

Fasting glucose (mmol/L)

1.054 (0.623, 1.485)

< 0.001

0.921 (0.449, 1.393)

< 0.001*

HbA1c (%)

0.562 (0.226, 0.898)

0.001

0.340 (-0.014, 0.694)

0.060

TC (mmol/L)

0.911 (-0.440, 2.262)

0.186

-

 

Log TG

8.175 (2.120, 14.229)

0.008

5.703 (-0.735, 12.141)

0.082

LDL-C (mmol/L)

-0.504 (-2.201, 1.193)

0.561

-

 

Log UACR

-5.501 (-7.762, -3.240)

< 0.001

-5.531 (-7.859, -3.203)

< 0.001*

   

R2 = 0.033

< 0.001*

  1. CKD, chronic kidney disease; BW, body weight; WC, waist circumference; BMI, body mass index; BP, blood pressure; HbA1c, glycated hemoglobin; TC, total cholesterol; TG, total triglyceride; Log, log transformation; LDL-C, low-density lipoprotein cholesterol; ALT, alanine aminotransferase; Cr, creatinine; eGFR, estimated glomerular filtration rate; UACR, urine albumin/creatinine ratio