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Table 1 Baseline characteristics between patients with renal recovery and non-recovery

From: Predictive performance of two types of urinary biomarkers for renal non-recovery in sepsis-associated acute kidney injury: a prospective observational study

Variables

Renal recovery

n = 87

Renal non-recovery

n = 54

p-value

Patient characteristics

   

Age (years)

60 ± 17

59 ± 18

0.658

Male

55 (63.2)

32 (59.3)

0.638

Body mass index (kg/m2)

24.4 ± 4.3

25.6 ± 3.7

0.079

APACHE II score

18.0 (15.8, 19.3)

18.5 (18.7, 23.2)

0.018

Non-renal SOFA score

6.0 (5.5, 7.4)

8.0 (6.8, 9.3)

0.020

Baseline SCr (mg/dL)

0.72 (0.70, 0.78)

0.76 (0.74, 0.81)

0.057

SCr at enrollment (mg/dL)

1.69 (1.50, 2.53)

2.55 (2.94, 4.70)

< 0.001

Chronic comorbidities

   

Chronic kidney disease

7 (8.0)

7 (13.0)

0.343

Hypertension

31 (47.1)

30 (55.6)

0.330

Diabetes

26 (29.9)

19 (35.2)

0.512

Coronary artery disease

21 (24.1)

6 (11.1)

0.056

COPD

5 (5.7)

5 (9.3)

0.507

Chronic liver disease

24 (27.6)

10 (18.5)

0.221

Sepsis severity

  

0.012

 Sepsis

75 (86.2)

37 (68.5)

 

 Septic shock

12 (13.8)

17 (31.5)

 

Admission type

   

Surgical

18 (21.4)

8 (14.8)

0.332

Medical

53 (60.9)

32 (59.3)

0.845

 Emergency

16 (18.4)

14 (25.9)

0.288

Characteristics at inclusion

   

Hemoglobin (g/L)

102.0 (100.1, 112.6)

106.5 (89.4, 108.1)

0.240

Lactate (mmol/L)

2.3 (2.9, 4.4)

3.7 (4.6, 8.2)

0.002

AKI stage at enrollment

  

< 0.001

 Stage 2

69 (79.3)

15 (34.1)

 

 Stage 3

18 (20.7)

29 (65.9)

 

Mechanical ventilation

74 (85.1)

43 (79.6)

0.404

Use of diuretics

38 (43.7)

29 (53.7)

0.247

  1. Abbreviations AKI, acute kidney injury; APACHE, Acute Physiology and Chronic Health Evaluation; COPD, chronic obstructive pulmonary disease; SCr, serum creatinine; SOFA, Sequential Organ Failure Assessment.