Table 1 Clinical features of anti-GBM patients with MN
From: Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report
Variable | Case 1 | Case 2 | Case 3 |
|---|---|---|---|
Age and gender | 67 F | 70 F | 53 F |
Co-morbidity | None | None | None |
Smoking status | Non-smoker | Non-smoker | Non-smoker |
Hydrocarbon exposure | None | None | None |
Prodromal infection | Yes | Yes | Yes |
Presenting symptoms | Lethargy, dyspnea, edema, gross hematuria | Lethargy, dyspnea, edema, gross hematuria | Edema, microscopic hematuria |
Renal status | AKI-RRT | AKI-RRT | AKI-RRT |
Hemoptysis | Yes | No | Yes |
C-reactive protein ug/dl | 265.02 | 44.59 | 93.67 |
Hemoglobin (g/L) | 89 | 74 | 84 |
WBC (× 109/L) | 15.89 | 23.03 | 14.22 |
Neutrophil (%) | 87.7 | 85.2 | 89.1 |
Platelets (× 109/L) | 291 | 75 | 120 |
Creatinine (mg/dL) | 7.79 | 6.33 | 13.57 |
Albumin (g/dL) | 2.5 | 2.3 | 2.1 |
Anti-GBM titer (IU/ml; normal < 6.9) |  > 200 | 165.2 |  > 200 |
ANCA | Negative | Negative | Negative |
PLA2R | Positive | Positive | Positive |
Treatment | Plasma exchange, cyclophosphamide, corticosteroids | Plasma exchange, cyclophosphamide, corticosteroids | Plasma exchange, cyclophosphamide, corticosteroids |
Follow-up (days) | Receiving OP hemodialysis | Recovered kidney function, CKD 3 stage | Died of cerebral infarction |
Last creatinine (mg/dL) | 4.52 | 2.84 | 10.18 |