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Table 2 Pathological features of anti-GBM patients with MN

From: Diagnosis of membranous nephropathy with Anti-GBM glomerulonephritis: a case series report

Variable

Case 1

Case 2

Case 3

MN stage

II

II

III

Glomerular lesions

 Sclerosis (% of total G)

0

7.7 (2/26 G)

6.5 (2/31 G)

 Mild mesangial proliferation (% of total G)

0

15.4 (4/26 G)

16.1 (5/31 G)

Crescent components

 Cellular crescents (% of total G)

88.2 (15/17 G)

76.9 (20/26 G)

77.4 (24/31 G)

 Circumferential cellular crescent

58.8 (10/17 G)

23.1 (6/26 G)

70.9 (22/31 G)

 Fibrous-cellular crescents (% of total G)

29.4 (5/17 G)

3.8 (1/26 G)

0

 Fibrous crescents (% of total G)

0

0

0

Tubular-interstitial damage a

 Tubular atrophy

2

1

1

 Interstitial fibrosis

2

1

2

 Interstitial monocyte and lymphocyte infiltration

2

2

2

  1. Abbreviations: G Glomeruli, GBM Glomerular basement membrane, MN Membranous nephropathy
  2. aSemi-quantitative scoring of the tubulointerstitial lesions according to the percentage of the area involved: score 0 as 0% of the cortical area or tubules; score 1 as 25% of the cortical area or tubules; score 2 as 25–50% of the cortical area or tubules; and score 3 as > 50% of the cortical area or tubules