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  1. Exercise and some pre-AKI diets have been shown to improve injury, apoptosis, and lipid profile. In this study, the effect of two different diets along with exercise training on acute kidney injury (AKI) was inve...

    Authors: Nazanin Sabet, Zahra Soltani, Mohammad Khaksari, Maryam Iranpour, Reza Malekpour Afshar, Fatemeh Mousavi Mehdiabadi and Alireza Raji-Amirhasani
    Citation: BMC Nephrology 2022 23:315
  2. Cholesterol crystal embolization syndrome (CES) occurs when an atherosclerotic plaque causes small-vessel embolization, resulting in multi-organ damage. Although CES is pathologically characterized by an infil...

    Authors: Tetsu Sakamoto, Takafumi Yamakawa, Keita Hirano, Arisa Kobayashi, Mio Kasai, Kiyoshi Koizumi, Takashi Yokoo, Satoru Komatsumoto, Toshimitsu Murohisa and Taro Shimizu
    Citation: BMC Nephrology 2022 23:314
  3. The M-type phospholipase A2 receptor (PLA2R)-associated idiopathic membranous nephropathy (IMN) is a common immune-related disease in adults. Vascular endothelial growth factor A (VEGFA) is the key mediator of...

    Authors: Ben Ke, Jinjing Huang, Zhibing Duan, Wen Shen, Yao Wu, Weiping Tu and Xiangdong Fang
    Citation: BMC Nephrology 2022 23:313
  4. Increased total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and decreased high-density lipoprotein cholesterol (HDL-C) concentrations, are established risk factors for ca...

    Authors: Misghina Weldegiorgis and Mark Woodward
    Citation: BMC Nephrology 2022 23:312

    The Correction to this article has been published in BMC Nephrology 2022 23:318

  5. Mechanisms by which AKI leads to CKD progression remain unclear. Several urine biomarkers have been identified as independent predictors of progressive CKD. It is unknown whether AKI may result in long-term ch...

    Authors: Ian E. McCoy, Jesse Y. Hsu, Joseph V. Bonventre, Chirag R. Parikh, Alan S. Go, Kathleen D. Liu, Ana C. Ricardo, Anand Srivastava, Debbie L. Cohen, Jiang He, Jing Chen, Panduranga S. Rao, Anthony N. Muiru and Chi-yuan Hsu
    Citation: BMC Nephrology 2022 23:311
  6. Performing percutaneous renal biopsy procedures in lupus nephritis (LN) and nephrotic syndrome presents a unique challenge to the nephrologist because of the risk of bleeding from the procedure and the hyperco...

    Authors: Muhammad Imran Kamarudin, Chandran Nadarajan and Mohamed Ashraf Mohamed Daud
    Citation: BMC Nephrology 2022 23:310
  7. Acute kidney injury (AKI) was common in the first two waves of the SARS-COV-2 pandemic in critically ill patients. A high percentage of these patients required renal replacement therapy and died in the hospital.

    Authors: Urmila Anandh, Amna Noorin, Syed Khurram Shehzad Kazmi, Sooraj Bannur, Syed Shahkar Ahmed Shah, Mehrin Farooq, Gopikrishna Yedlapati, Waseem Amer, Bonthu Prasad and Indranil Dasgupta
    Citation: BMC Nephrology 2022 23:308
  8. Plasma triglyceride (TG) levels are a significant risk factor for cardiovascular disease (CVD). The APOA5 gene is one of the crucial factors in plasma TG metabolism regulation. The rs662799 polymorphism in the AP...

    Authors: Jerry Jacob, Sylwia Boczkowska, Wojciech Zaluska and Monika Buraczynska
    Citation: BMC Nephrology 2022 23:307
  9. Idiopathic membranous nephropathy (iMN) is recognized as an organ-specific autoimmune disease, mainly caused by anti-PLA2R antibody. This study aimed to study between anti-PLA2R antibody level at diagnosis and...

    Authors: Bihua Wang, Zhidan Zhu, Feng Huang, Haowen Huang, Luxia Tu, Ying Wang, Linfeng Zheng, Jing Zhou and Xin Wei
    Citation: BMC Nephrology 2022 23:306

    The Correction to this article has been published in BMC Nephrology 2022 23:321

  10. Nephrotic syndrome (NS) is associated with increased risk of thromboembolic events (TE) adding to the morbidity and mortality. International guidelines recommend prophylactic anticoagulation in patients with N...

    Authors: Sarah Kelddal, Anne-Mette Hvas, Erik Lerkevang Grove and Henrik Birn
    Citation: BMC Nephrology 2022 23:305
  11. There is a growing literature on guidelines regarding Ramadan fasting for chronic kidney disease (CKD) patients. However, most studies only consider the impact of fasting on renal function. This study addition...

    Authors: Latifa Baynouna AlKetbi, Nico Nagelkerke, Amal AlZarouni, Mouza Al Kuwaiti, Mona Al Ghafli, Salama Al Qahtani, Bushra Al Kaabi, Mariam Al Kaabi, Ali Al Ahbabi, Yousif Al Zeyodi, Kholoud Al Ketheri, Khawla Al Nabooda, Khadija Al Tenaji, Ali AlAlawi and Hanan Abdelbaqi
    Citation: BMC Nephrology 2022 23:304
  12. Increasing evidence suggests that immune cell infiltration contributes to the pathogenesis and progression of diabetic nephropathy (DN). We aim to unveil the immune infiltration pattern in the glomerulus of DN...

    Authors: Wei ZHOU, Yaoyu LIU, Qinghong Hu, Jiuyao ZHOU and Hua LIN
    Citation: BMC Nephrology 2022 23:303
  13. Treatment burden refers to the work involved in managing one’s health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specif...

    Authors: Elizabeth C. Lorenz, Tanya M. Petterson, Isabella Zaniletti, Kandace A. Lackore, Bradley K. Johnson, Martin L. Mai, Sumi S. Nair, Andrew J. Bentall, Kathleen J. Yost and David T. Eton
    Citation: BMC Nephrology 2022 23:301
  14. Hemodialysis tunneled catheters are prone to failure due to infection or thrombosis. Prediction of catheter dysfunction chance and finding the predisposing risk factors might help clinicians to prolong proper ...

    Authors: Arash Mohazzab, Morteza Khavanin Zadeh, Paria Dehesh, Neda Abdolvand, Zhaleh Rahimi and Sahar Rahmani
    Citation: BMC Nephrology 2022 23:300
  15. Chronic kidney disease (CKD) is a recognized risk factor for severe complications in COVID-19. Our objective was to analyze the association between kidney function / T and B lymphocyte modulatory factors and r...

    Authors: Ladan Mansouri, Senka Sendic, Sebastian Havervall, Charlotte Thålin, Stefan H. Jacobson and Joachim Lundahl
    Citation: BMC Nephrology 2022 23:299
  16. Post-dialysis fatigue is a common and distressing complaint in patients on hemodialysis (HD). The dialysis recovery time (DRT) is a recent and reliable method of Post-dialysis fatigue assessment. We aimed to i...

    Authors: Mohamed Mamdouh Elsayed, Montasser Mohamed Zeid, Osama Mohamed Refai Hamza and Noha Mohamed Elkholy
    Citation: BMC Nephrology 2022 23:298
  17. The transport of water and urea through the erythrocyte membrane is facilitated by aquaporins such as aquaglyceroporin (AQP3), and type B urea transporters (UT-B). As they may play an important role in osmotic...

    Authors: Rafał Zwiech, Agnieszka Bruzda-Zwiech, Ewa Balcerczak, Joanna Szczepańska, Adrian Krygier, Beata Małachowska, Dominika Michałek and Dagmara Szmajda-Krygier
    Citation: BMC Nephrology 2022 23:297
  18. Endocapillary hypercellularity (ECHC) is commonly seen in class IV lupus nephritis (LN), the most common and severe LN in children. Factors influencing early complete remission (CR) in pediatric class IV LN ha...

    Authors: Chunzhen Li, Yanan Han, Lili Zhang, Zhiguo Chen, Mei Jin and Suzhen Sun
    Citation: BMC Nephrology 2022 23:296
  19. Anemia has been reported as a risk factor for chronic kidney disease (CKD) progression. However, there are still few studies examining the relationship between specific hemoglobin (Hb) levels and renal prognos...

    Authors: Wushan Pan, Yong Han, Haofei Hu and Yongcheng He
    Citation: BMC Nephrology 2022 23:295
  20. Acute kidney injury is a common complication in solid organ transplants, notably liver transplantation. The MELD is a score validated to predict mortality of cirrhotic patients, which is also used for organ al...

    Authors: Paulo Ricardo Gessolo Lins, Roberto Camargo Narciso, Leonardo Rolim Ferraz, Virgilio Gonçalves Pereira, Ben-Hur Ferraz-Neto, Marcio Dias De Almeida, Bento Fortunato Cardoso Dos Santos, Oscar Fernando Pavão Dos Santos, Júlio Cesar Martins Monte, Marcelino Souza Durão Júnior and Marcelo Costa Batista
    Citation: BMC Nephrology 2022 23:294
  21. The association between cardiac complications, such as heart failure (HF), and chronic kidney disease (CKD) is well known. In this study, we examined the effectiveness and safety of treatment with neprilysin i...

    Authors: María Dolores Martínez-Esteban, Teresa Vázquez-Sánchez, Rafael Pozo-Álvarez, Alicia Moreno-Ortiz, Juana Alonso-Titos, Guillermo Martín-Reyes, Pedro Ruiz-Esteban, Daniel Gaitán-Román and Domingo Hernández
    Citation: BMC Nephrology 2022 23:293
  22. Telehealth could potentially increase independency and autonomy of patients treated with peritoneal dialysis (PD). Moreover, it might improve clinical and economic outcomes. The demand for telehealth modalitie...

    Authors: Geertje K. M. Biebuyck, Aegida Neradova, Carola W. H. de Fijter and Lily Jakulj
    Citation: BMC Nephrology 2022 23:292
  23. Hyperphosphatemia occurs frequently in end-stage renal disease patients on hemodialysis and is associated with increased mortality. Hyperphosphatemia contributes to vascular calcification in these patients, bu...

    Authors: Jinwoo Jung, Haekyung Jeon-Slaughter, Hang Nguyen, Jiten Patel, Kamalanathan K. Sambandam, Shani Shastri and Peter Noel Van Buren
    Citation: BMC Nephrology 2022 23:291
  24. Tuberculosis (TBC) in solid organ transplant recipients represents a severe complication. The incidence among transplant recipients is higher than in the general population, and the diagnosis and treatment rem...

    Authors: Kamila Bednarova, Janka Slatinska, Ondrej Fabian, Pavel Wohl, Emilia Kopecka and Ondrej Viklicky
    Citation: BMC Nephrology 2022 23:290
  25. Restriction of sodium intake is routinely recommended for patients with chronic kidney disease (CKD). Whether or not sodium intake is associated with the progression of CKD and mortality remains uncertain. We ...

    Authors: Cecília Malheiro Cury, Vanessa Burgugi Banin, Pamela Falbo dos Reis, Jacqueline Costa Teixeira Caramori, Pasqual Barretti, Luís Gustavo Modelli de Andrade and Luis Cuadrado Martin
    Citation: BMC Nephrology 2022 23:289
  26. Glycated albumin (GA) is known to reflect the current inflammatory burden in non-diabetes mellitus (DM) patients. In this study, we investigated whether GA at diagnosis could reflect the cross-sectional activi...

    Authors: Pil Gyu Park, Jung Yoon Pyo, Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee
    Citation: BMC Nephrology 2022 23:288
  27. The electronic health record (EHR), utilized to apply statistical methodology, assists provider decision-making, including during the care of chronic kidney disease (CKD) patients. When estimated glomerular fi...

    Authors: Reyhaneh Zafarnejad, Steven Dumbauld, Diane Dumbauld, Mohammad Adibuzzaman, Paul Griffin and Edwin Rutsky
    Citation: BMC Nephrology 2022 23:287
  28. In chronic kidney disease (CKD), like in IgA nephropathy (IgAN), cardiovascular (CV) mortality and morbidity are many times higher than in the general population, and left ventricular hypertrophy (LVH) is an i...

    Authors: Balázs Sági, István Késői, Tibor Vas, Botond Csiky, Judit Nagy and Tibor József Kovács
    Citation: BMC Nephrology 2022 23:285
  29. Kidney transplantation is an effective treatment for end-stage renal disease (ESRD). Delayed graft function (DGF) is a common complication after kidney transplantation and exerts substantial effects on graft f...

    Authors: Shitao Zhao, Yuan Liu, Chen Zhou, Zide Chen, Zeyu Cai, JiaLiang Han, Jiansheng Xiao and Qi Xiao
    Citation: BMC Nephrology 2022 23:284
  30. Kidney transplantation in older people has increased, however older transplant recipients experience mixed outcomes that invariably impacts on their quality of life. The increased vulnerability of older end st...

    Authors: Amarpreet K. Thind, Annabel Rule, Dawn Goodall, Shuli Levy, Sarah Brice, Frank J. M. F. Dor, Nicola Evans, David Ospalla, Nicola Thomas, David Wellsted, Lina Johansson, Michelle Willicombe and Edwina A. Brown
    Citation: BMC Nephrology 2022 23:283
  31. Community engagement is essential for effective research when addressing issues important to both the community and researchers. Despite its effectiveness, there is limited published evidence concerning the ev...

    Authors: Angie Aguilar-González, Randall Lou-Meda, André Chocó-Cedillos and Louise Moist
    Citation: BMC Nephrology 2022 23:282
  32. Hyperkalaemia is common in patients with chronic kidney disease (CKD) and is associated with a range of adverse outcomes. Historically, options for management of chronic hyperkalaemia in the outpatient setting...

    Authors: Kun Kim, Josefine Fagerström, Gengshi Chen, Zoya Lagunova, Hans Furuland and Phil McEwan
    Citation: BMC Nephrology 2022 23:281
  33. Many individuals living with chronic kidney disease (CKD) have comorbid Type 2 diabetes (T2D). We sought to explore if efficacious interventions that improve glycemic control may also have potential to reduce ...

    Authors: McKenzie K. Roddy, Lindsay S. Mayberry, Devika Nair and Kerri L. Cavanaugh
    Citation: BMC Nephrology 2022 23:280
  34. The first case of Taralomyces flavus infection in human and peritoneal dialysis (PD) patient after exposure to biocontrol agent fumes is reported here.

    Authors: Phanit Sookto, Talerngsak Kanjanabuch, Tamonwan Chamroensakchai, Nisa Thongbor and Somchai Eiam-Ong
    Citation: BMC Nephrology 2022 23:279
  35. Monoclonal gammopathy of renal significance (MGRS) encompasses a heterogeneous group of kidney diseases in which a monoclonal immunoglobulin secreted by a clone of B cells or plasma cells causes kidney damage ...

    Authors: Gabriel Brayan Gutiérrez-Peredo, José César Batista Oliveira Filho, Iris Montaño-Castellón, Andrea Jimena Gutiérrez-Peredo, Edvan de Queiroz Crusoé and Dimitri Gusmao-Flores
    Citation: BMC Nephrology 2022 23:278
  36. The number of chronic kidney disease (CKD) patients continues to increase worldwide. CKD patients need to take phosphate binders to manage serum phosphorus concentrations. Currently, several types of phosphate...

    Authors: Akiko Hashimoto, Jiaqi Gao, Yuki Kanome, Yukihiro Ogawa, Masaharu Nakatsu, Masahiro Kohno and Koji Fukui
    Citation: BMC Nephrology 2022 23:277
  37. Patients with end-stage kidney disease (ESKD) may choose to undergo dialysis in-center or at home, but uptake of home dialysis in the US has been minimal despite its benefits over in-center dialysis. Factors t...

    Authors: Miriam Vélez-Bermúdez, Jenna L. Adamowicz, Natoshia M. Askelson, Susan K. Lutgendorf, Mony Fraer and Alan J. Christensen
    Citation: BMC Nephrology 2022 23:276
  38. Over the last three decades, the mesoamerican region has seen an increase in the frequency of patients diagnosed with Chronic Kidney Disease of nontraditional causes (CKDnt) also known as Meso-American Nephrop...

    Authors: Karen Courville, Norman Bustamante, Bárbara Hurtado, Maydelin Pecchio, Clarissa Rodríguez, Virginia Núñez-Samudio and Iván Landires
    Citation: BMC Nephrology 2022 23:275
  39. Haemostatic derangements are thought to be due to an imbalance between hepatic synthesis of pro-coagulants and urinary losses of anticoagulants.

    Authors: Chioma L. Odimegwu, Anthony N. Ikefuna, Henrietta U. Okafor, Theresa Nwagha, Agozie Ubesie and Josephat M. Chinawa
    Citation: BMC Nephrology 2022 23:274
  40. Chronic kidney disease (CKD) is responsible for large personal health and societal burdens. Screening populations at higher risk for CKD is effective to initiate earlier treatment and decelerate disease progre...

    Authors: Susanne Stolpe, Bernd Kowall, Denise Zwanziger, Mirjam Frank, Karl-Heinz Jöckel, Raimund Erbel and Andreas Stang
    Citation: BMC Nephrology 2022 23:272
  41. We report a case of a patient who suffered thrombosis of a radial artery-cephalic vein fistula accompanied by aneurysm and a single outflow path of the elbow perforating vein. We performed open surgery combine...

    Authors: Ziqiang Wang, Yifen Hong, Zefeng Wei, Juan Chen, Li Li and Yongjun Zhu
    Citation: BMC Nephrology 2022 23:271
  42. Currently, there is a lack of clinical indicators that can accurately distinguish diabetic kidney disease (DKD) from non-diabetic kidney disease (NDKD) in type 2 diabetes. The purpose of this study was to inve...

    Authors: Jing Wei, Bo Wang, Feng-jie Shen, Ting-ting Zhang, Zan Duan and Dong-mei Zhou
    Citation: BMC Nephrology 2022 23:270
  43. Many people living with chronic kidney disease (CKD) are iron deficient, even though they may not be anaemic. The Iron and Muscle study aims to evaluate whether iron supplementation reduces symptoms of fatigue...

    Authors: Sharlene A. Greenwood, Nicholas Beckley-Hoelscher, Elham Asgari, Salma Ayis, Luke A. Baker, Debasish Banerjee, Sunil Bhandari, Kate Bramham, Joseph Chilcot, James Burton, Philip A. Kalra, Courtney J. Lightfoot, Kieran McCafferty, Thomas H. Mercer, Darlington O. Okonko, Benjamin Oliveira…
    Citation: BMC Nephrology 2022 23:268
  44. Gitelman syndrome (GS) is a rare autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we report, for the first time, a case of GS overlapping nephrotic syndrome (NS) related to PLA2R-associated m...

    Authors: Xiafei Guo, Shanshen Yu, Jia Sun and Lijun Mou
    Citation: BMC Nephrology 2022 23:267
  45. Good knowledge and early identification of chronic kidney disease (CKD) can help in preventing disease progression in its early stages and reducing undesired outcomes. The aim of the current study was to asses...

    Authors: Samar Younes, Nisreen Mourad, Jihan Safwan, Mariam Dabbous, Mohamad Rahal, Marah Al Nabulsi and Fouad Sakr
    Citation: BMC Nephrology 2022 23:266

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