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  1. Chemokine (C–C motif) receptor 2 (CCR2) is involved in important physiological and pathological processes, such as inflammation and autoimmune diseases. Abnormal immune and inflammatory responses play a critic...

    Authors: Yanjie Shen, Zhiqing Zhu, Rui Wang, Lili Yan, Shuaichen Sun, Ling Lu, Zhenhua Ren and Qin Zhang
    Citation: BMC Nephrology 2022 23:215
    Content type: Research Published on:

  2. Lupus nephritis (LN) is the most common severe complication of systemic lupus erythematosus (SLE) which results in high morbidity and mortality. Up to 60% of adult patients with SLE develop the renal disease w...

    Authors: Gebre-Mariam Tsegay Hailu, Shemsu Umer Hussen, Seifemichael Getachew and Alemseged Beyene Berha
    Citation: BMC Nephrology 2022 23:214
    Content type: Research Published on:

  3. CKD-associated pruritus (chronic kidney disease-associated pruritus) is one of the common symptoms in hemodialysis patients, with a major effect on sleep quality because it occurs at night. The main objective ...

    Authors: Mefleh Daraghmeh, Montaser Badran, Ahmad Janajreh, Mohanad Hassan, Adham Abu Taha, Amer A. Koni and Sa’ed H. Zyoud
    Citation: BMC Nephrology 2022 23:213
    Content type: Research Published on:

  4. Hypercalcemic hyperparathyroidism has been associated with poor outcomes after kidney transplantation (KTx). However, the clinical implications of normocalcemic hyperparathyroidism after KTx are unclear. This ...

    Authors: Manabu Okada, Yoshihiro Tominaga, Tetsuhiko Sato, Toshihide Tomosugi, Kenta Futamura, Takahisa Hiramitsu, Toshihiro Ichimori, Norihiko Goto, Shunji Narumi, Takaaki Kobayashi, Kazuharu Uchida and Yoshihiko Watarai
    Citation: BMC Nephrology 2022 23:212
    Content type: Research Published on:

  5. T-type calcium channels (TTCC) are low voltage activated channels that are widely expressed in the heart, smooth muscle and neurons. They are known to impact on cell cycle progression in cancer and smooth musc...

    Authors: Sudha Priya Soundara Pandi, Michael J. Shattock, Bruce M. Hendry and Claire C. Sharpe
    Citation: BMC Nephrology 2022 23:211
    Content type: Research Published on:

  6. Atherosclerotic renovascular disease (ARVD) often follows an asymptomatic chronic course which may be undetected for many years. However, there are certain critical acute presentations associated with ARVD and...

    Authors: Áine de Bhailis, Saif Al-Chalabi, Rodrigo Hagemann, Sara Ibrahim, Amy Hudson, Edward Lake, Constantina Chysochou, Darren Green and Philip A. Kalra
    Citation: BMC Nephrology 2022 23:210
    Content type: Case report Published on:

  7. Stage 5 chronic kidney disease (CKD) patients often experience decisional conflict when faced with the selection between the initiation of dialysis and conservative care. The study examined the effects of a br...

    Authors: Kitty Chan, Frances Kam Yuet Wong, Suet Lai Tam, Ching Ping Kwok, Yuen Ping Fung and Ping Nam Wong
    Citation: BMC Nephrology 2022 23:209
    Content type: Research article Published on:

  8. Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality and morbidity associated with DKD are increasing with the global prevalence of type 2 diabetes. Chronic, sub-clinical, ...

    Authors: Alexis Hofherr, Julie Williams, Li-Ming Gan, Magnus Söderberg, Pernille B. L. Hansen and Kevin J. Woollard
    Citation: BMC Nephrology 2022 23:208
    Content type: Review Published on:

  9. Technique failure is more likely to occur during the first 12 months after peritoneal dialysis (PD) initiation, which is a great challenge encountered in PD patients. The aim of this study was to investigate t...

    Authors: Xiao Dong, Haishan Wu, Hongjian Ye, Chunyan Yi, Xiangwen Diao, Ruihua Liu, Haiping Mao, Fengxian Huang, Xueqing Yu and Xiao Yang
    Citation: BMC Nephrology 2022 23:207
    Content type: Research Published on:

  11. Progression of chronic kidney disease (CKD) may be delayed if patients engage in healthy lifestyle behaviors. However, lifestyle adherence is very difficult and may be influenced by problems in psychosocial fu...

    Authors: Cinderella K. Cardol, Karin Boslooper-Meulenbelt, Henriët van Middendorp, Yvette Meuleman, Andrea W. M. Evers and Sandra van Dijk
    Citation: BMC Nephrology 2022 23:205
    Content type: Research Published on:

  12. For the optimal management of patients with both allograft kidneys and native kidney diseases, the recognition of the histological features associated with older age is important. This is because most patholog...

    Authors: Satoshi Hara, Yutaka Yamaguchi, Takeshi Zoshima, Ichiro Mizushima, Kazunori Yamada, Ryo Inoue, Hisao Muto, Kazuaki Mizutomi, Masayoshi Hirata, Hideo Araki, Ryoichi Miyazaki and Mitsuhiro Kawano
    Citation: BMC Nephrology 2022 23:204
    Content type: Research Published on:

  13. Chronic kidney disease (CKD) is one of the major global causes of mortality, described as the most neglected chronic disease. This study aimed to determine the prevalence and determinants of CKD in the setting...

    Authors: Ali Dehghani, Sadegh Alishavandi, Nader Nourimajalan, Hossein Fallahzadeh and Vahid Rahmanian
    Citation: BMC Nephrology 2022 23:203
    Content type: Research Published on:

  14. In critically ill patients, acute pain occurs frequently, causes sympathetic activation, release of inflammatory mediators, and potential organ dysfunction, with the kidneys potentially sensitive to inflammati...

    Authors: Laura Herranz Prinz, Isac de Castro, Luciano de Cesar Pontes Azevedo and Jose Mauro Vieira Jr
    Citation: BMC Nephrology 2022 23:202
    Content type: Research article Published on:

  15. Qualitative patient interviews and patient-reported outcome instruments are important tools to understand the patient experience of disease. The aim of this study was to use patient interviews to identify conc...

    Authors: Anna Rydén, Stephen Nolan, Joshua Maher, Oren Meyers, Anna Kündig and Magnus Bjursell
    Citation: BMC Nephrology 2022 23:201
    Content type: Research Published on:

  16. Left ventricular hypertrophy (LVH) is common among patients undergoing dialysis. However, the dynamic structural changes of LV are rarely discussed. The study aimed to investigate the prognostic significance o...

    Authors: Yun Chen, Shuqi Dai, Xiaolin Ge, Da Shang, Qionghong Xie, Chuanming Hao and Tongying Zhu
    Citation: BMC Nephrology 2022 23:200
    Content type: Research Published on:

  17. Dialysis patients and immunosuppressed renal patients are at increased risk of COVID-19 and were excluded from vaccine trials. We conducted a prospective multicentre study to assess SARS-CoV-2 vaccine antibody...

    Authors: Rona M. Smith, Daniel J. Cooper, Rainer Doffinger, Hannah Stacey, Abdulrahman Al-Mohammad, Ian Goodfellow, Stephen Baker, Sara Lear, Myra Hosmilo, Nicholas Pritchard, Nicholas Torpey, David Jayne, Vivien Yiu, Anil Chalisey, Jacinta Lee, Enric Vilnar…
    Citation: BMC Nephrology 2022 23:199
    Content type: Research Published on:

  19. Chronic kidney disease(CKD) is a major public health issue and is highly prevalent in the general population. Leptin is an adipose tissue-derived endocrine factor that has been associated with several metaboli...

    Authors: Yon Chul Park, Solam Lee, Young-Sang Kim, Jae-Min Park, Kunhee Han, Hunju Lee, Kyung-Won Hong, Jong-Koo Kim, Eun Suk Cho, Tae-Ha Chung, Bom-Taeck Kim and Sang Baek Koh
    Citation: BMC Nephrology 2022 23:197
    Content type: Research article Published on:

  21. To explore the biological variation (BV) of kidney injury markers in serum and urine of healthy subjects within 24 hours to assist with interpretation of future studies using these biomarkers in the context of...

    Authors: Li-Rui Kong, Fei Wei, Da-Hai He, Chao-Qiong Zhou, Hong-chuan Li, Feng Wu, Yu Luo, Jian-wei Luo, Qian-rong Xie, Hai Peng and Yan Zhang
    Citation: BMC Nephrology 2022 23:195
    Content type: Research Published on:

  22. Genus Desulfovibrio species is a sulphate-reducing anaerobic gram-negative rod that resides in the human oral cavity and intestinal tract. It was reported as the causative pathogen of bacteraemia and abdominal in...

    Authors: Yoshiki Okamoto, Yoei Miyabe, Momoko Seki, Yusuke Ushio, Keisuke Sato, Eri Kasama, Kenichi Akiyama, Kazunori Karasawa, Keiko Uchida, Ken Kikuchi, Kosaku Nitta, Takahito Moriyama and Junichi Hoshino
    Citation: BMC Nephrology 2022 23:194
    Content type: Case report Published on:

  23. Despite the high economic and mortality burden of chronic kidney disease, studies on survival and predictors of mortality among patients on hemodialysis in Ethiopia especially in the Amhara region are scarce c...

    Authors: Sewnet Getaye Workie, Taye Abuhay Zewale, Gizachew Tadesse Wassie, Makda Abate Belew and Eleni Dagnaw Abeje
    Citation: BMC Nephrology 2022 23:193
    Content type: Research Published on:

  24. Hyperphosphatemia (HP) is associated with vascular calcification (VC) in chronic kidney disease (CKD). However, relationship between HP-induced-endothelial extracellular vesicles (HP-EC-EVs) and VC is unclear,...

    Authors: Zhong Peng, Yingjie Duan, Shuzhu Zhong, Juan Chen, Jianlong Li and Zhangxiu He
    Citation: BMC Nephrology 2022 23:192
    Content type: Research Published on:

  25. The objective of this study was to evaluate the reported associations between the syndrome of inappropriate antidiuretic hormone secretion (SIADH) and a variety of proton pump inhibitors (PPI) through analysis...

    Authors: Mengmeng Wang, Lingjian Zhang, Min Jia, Junyan Wang, Zhiwen Shen, Shuyue Wang, Xinghui Zhang, Jing Xu, Zheng Zheng, Xuanrui Lv, Xiaoyu Zong, Hui Li, Jin Zhou, Tong Meng, Mingzhu Chen, Bin Zhao…
    Citation: BMC Nephrology 2022 23:191
    Content type: Research Published on:

  26. Assisted home hemodialysis is a therapeutic modality for patients diagnosed with end-stage renal disease who require dialysis replacement therapy and have concomitant health limitations that prevent them from ...

    Authors: Raquel Scofano, Alexandra Monteiro and Luciana Motta
    Citation: BMC Nephrology 2022 23:190
    Content type: Research Published on:

  27. The mortality rate associated with coronavirus disease 2019 (COVID-19) is high among haemodialyzed patients. We sought to describe the serological status of haemodialysis patients having received up to three d...

    Authors: Jean-François Verdier, Sonia Boyer, Florence Chalmin, Ahmed Jeribi, Caroline Egasse, Marie France Maggi, Philippe Auvray and Tarik Yalaoui
    Citation: BMC Nephrology 2022 23:189
    Content type: Research Published on:

  28. Acute kidney disease (AKD) evolves a spectrum of acute and subacute kidney disease requiring a global strategy to address. The present study aimed to explore the impact of AKD on the prognosis of ischemic stroke.

    Authors: Yilun Zhou, Dongxue Wang, Hao Li, Yuesong Pan, Xianglong Xiang, Yu Wu, Xuewei Xie, Xianwei Wang, Yang Luo, Xia Meng, Jinxi Lin, Hong Wang, Yong Huo, Kunihiro Matsushita, Jing Chen, Fan Fan Hou…
    Citation: BMC Nephrology 2022 23:188
    Content type: Research Published on:

  29. Patients who are HLA-sensitized are at high risk for early antibody-mediated rejection (AMR) and worse outcomes. Therefore, it is crucial to detect the presence of donor-specific antibodies (DSAs) using pretra...

    Authors: Duangtawan Thammanichanond, Chutima Tammakorn, Atiporn Ingsathit, Suchin Worawichawong and Premsant Sangkum
    Citation: BMC Nephrology 2022 23:187
    Content type: Case report Published on:

  30. Patients on hemodialysis often suffer from reduced muscle strength and exercise capacity due to the decreased quantity and quality of muscle. Cumulative studies showed ultrasound echo intensity (EI) had great ...

    Authors: Junzhen Wu, Haiqing Luo, Shunrong Ren, Longxiang Shen, Dongsheng Cheng and Niansong Wang
    Citation: BMC Nephrology 2022 23:186
    Content type: Research Published on:

  31. To explore the technical specifications and clinical outcomes of thrombosed aneurysmal haemodialysis arteriovenous fistula (AVF) treated with ultrasound-guided percutaneous transluminal angioplasty combined wi...

    Authors: Wei Liu, Meng Wu, Xu Wang, Xiao-kang Huang, Wen-jiao Cai, Teng-yun Ding, Liang-liang Duan, Rui Qiao and Yong-gui Wu
    Citation: BMC Nephrology 2022 23:185
    Content type: Research Published on:

  32. Statins therapy has been primarily recommended for the prevention of cardiovascular risk in patients with chronic kidney diseases. Statins has also been proved some benefits in lipid-induced kidney diseases. T...

    Authors: Ani Wang, Yu Lin, Baien Liang, Xiaoduo Zhao, Miaojuan Qiu, Hui Huang, Chunling Li, Weidong Wang and Yonglun Kong
    Citation: BMC Nephrology 2022 23:184
    Content type: Research Published on:

  33. Kidney transplant recipients have an increased risk of complications from COVID-19. However, data on the risk of allograft damage or death in kidney transplant recipients recovering from COVID-19 is limited. I...

    Authors: Erol Demir, Zuhal Atan Ucar, Hamad Dheir, Ramazan Danis, Berna Yelken, Murathan Uyar, Ergun Parmaksiz, Ayse Serra Artan, Ayse Sinangil, Ozgur Merhametsiz, Serap Yadigar, Ahmet Burak Dirim, Baris Akin, Nurana Garayeva, Seda Safak and Aydin Turkmen
    Citation: BMC Nephrology 2022 23:183
    Content type: Research Published on:

  34. Dent disease is an X-linked disorder characterized by low molecular weight proteinuria (LMWP), hypercalciuria, nephrolithiasis and chronic kidney disease (CKD). It is caused by mutations in the chloride voltag...

    Authors: Eleni Drosataki, Sevasti Maragkou, Kleio Dermitzaki, Ioanna Stavrakaki, Dimitra Lygerou, Helen Latsoudis, Christos Pleros, Ioannis Petrakis, Ioannis Zaganas and Kostas Stylianou
    Citation: BMC Nephrology 2022 23:182
    Content type: Case report Published on:

  35. Bartonella endocarditis is often a diagnostic challenge due to its variable clinical manifestations, especially when it is first presented with involvement of organs other than skin and lymph nodes, such as t...

    Authors: Shunhua Guo, Neha D. Pottanat, Jeremy L. Herrmann and Marcus S. Schamberger
    Citation: BMC Nephrology 2022 23:181
    Content type: Case report Published on:

  38. Recurrence of IgA nephropathy (IgAN) after kidney transplantation occurs in about 30% of patients. The relevance of recurrence for the long-term graft survival is expected to increase, since graft survival con...

    Authors: Cédric Jäger, Susanne Stampf, Karen Molyneux, Jonathan Barratt, Déla Golshayan, Karine Hadaya, Uyen Huynh-Do, Francoise-Isabelle Binet, Thomas F Mueller, Michael Koller and Min Jeong Kim
    Citation: BMC Nephrology 2022 23:178
    Content type: Research Published on:

  39. Elderly hemodialysis patients have a higher rate of mortality than nonelderly hemodialysis patients. Recent studies shown that the serum uric acid to creatinine ratio (SUA/Scr) was associated with all-cause mo...

    Authors: Zhihui Ding, Yao Fan, Chunlei Yao and Liubao Gu
    Citation: BMC Nephrology 2022 23:177
    Content type: Research Published on:

  40. The coronavirus disease (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produced a pandemic since March 2020 by affecting more than 243 million people with more than 5 mil...

    Authors: Laura Tapoi, Mugurel Apetrii, Gianina Dodi, Ionut Nistor, Luminita Voroneanu, Lucian Siriteanu, Mihai Onofriescu, Mehmet Kanbay and Adrian Covic
    Citation: BMC Nephrology 2022 23:176
    Content type: Study protocol Published on:

  41. Coronavirus disease 2019 (COVID-19) is identified as the pneumonia and acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The intravascular thrombotic ph...

    Authors: Huayan Huang, Chunguang Lin, Yongdong Chen, Xiuting Wu, Miaomiao Lin, Siqi Chen and Kai Li
    Citation: BMC Nephrology 2022 23:175
    Content type: Case report Published on:

  43. This study aims to evaluate the impact of multidisciplinary pre-dialysis care (MDPC) on the risks of peritonitis, technique failure and mortality in peritoneal dialysis (PD) patients.

    Authors: I-Kuan Wang, Tung-Min Yu, Tzung-Hai Yen, Hei-Tung Yip, Ping-Chin Lai, Chi-Yuan Li, Kuo-Ting Sun and Fung-Chang Sung
    Citation: BMC Nephrology 2022 23:173
    Content type: Research Published on:

  44. The dysfunction of RNA binding proteins (RBPs) is associated with various inflammation and cancer. The occurrence and progression of tumors are closely related to the abnormal expression of RBPs. There are few...

    Authors: Wenkai Han, Bohao Fan, Yongsheng Huang, Xiongbao Wang, Zhao Zhang, Gangli Gu and Zhao Liu
    Citation: BMC Nephrology 2022 23:172
    Content type: Research Published on:

    The Correction to this article has been published in BMC Nephrology 2022 23:252

  46. Gitelman Syndrome (GS) is a hereditary tubulopathy associated with a biallelic inactivating mutations of the SLC12A3 gene encoding the thiazide-sensitive sodium-chloride cotransporter (NCCT). The typical clinical...

    Authors: Mariusz Flisiński, Ewa Skalska, Barbara Mączyńska, Natalia Butt-Hussaim, Agnieszka Sobczyńska-Tomaszewska, Olga Haus and Jacek Manitius
    Citation: BMC Nephrology 2022 23:170
    Content type: Case report Published on:

  47. Prevalence of Fabry disease amongst Chronic Kidney Disease (CKD) patients on haemodialysis has been shown to be approximately 0.2%.

    Authors: Andrew Mallett, Phoebe Jane Kearey, Anne Cameron, Helen G. Healy, Charles Denaro, Mark Thomas, Vincent W. Lee, Samantha Louise Stark, Maria Fuller, Zaimin Wang and Wendy E. Hoy
    Citation: BMC Nephrology 2022 23:169
    Content type: Research Published on:

  49. The burden of both acute kidney injury and chronic kidney disease is on the rise globally. In sierra Leone, there has been no data on renal patients or admissions. This study intends to close this gap in knowl...

    Authors: Joshua Coker, Onome Abiri, Obinna Jude Nwosu, Alhaji Gbla, Adetunji Wilson Taylor and Durodami Lisk
    Citation: BMC Nephrology 2022 23:167
    Content type: Research Published on:

  50. A diagnosis of chronic kidney disease has been strongly associated with cardiovascular disease and mortality in a number of studies, but the association with specific causes of death has not been assessed in d...

    Authors: Dagfinn Aune, Xibin Sun, Jing Nie, Wentao Huang, Bing Liao and Yafeng Wang
    Citation: BMC Nephrology 2022 23:165
    Content type: Research Published on:
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BMC Nephrology

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