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  1. Anemia and electrolyte disturbances are adverse outcomes of chronic kidney disease (CKD). This study explored the association between metabolic parameters with anemia and electrolyte and mineral disorders amon...

    Authors: Adi Lukas Kurniawan, Ya-Lan Yang, Chien-Yeh Hsu, Rathi Paramastri, Hsiu-An Lee, Po-Yuan Ni, Mei-Yun Chin and Jane C.-J. Chao
    Citation: BMC Nephrology 2021 22:385
  2. Hemodialysis patients are among high-risk groups for COVID-19. Africa is the continent with the lowest number of cases in the general population but we have little information about the disease burden in dialy...

    Authors: Sidy Mohamed Seck, Moustapha Mbow, Yaya Kane, Mouhamadou Moustapha Cisse, Gnagna Faye, Adama Kama, Moussa Sarr, Pamela Nitcheu, Mohamed Dahaba, Ibrahima Mbemba Diallo, Mame Selly Diawara, Lotingo Nehemie Motoula Latou, Yacine Dia and Souleymane Mboup
    Citation: BMC Nephrology 2021 22:384
  3. Family caregivers of hemodialysis patients are the first and most crucial source of care at home. They experience many problems in the care of hemodialysis patients, which can affect their quality of life and ...

    Authors: Seyedeh Azam Sajadi, Zahra Farsi, Roghayeh Akbari, Atefeh Sadeghi and Abazar Akbarzadeh Pasha
    Citation: BMC Nephrology 2021 22:383
  4. It has been noticed for years that ultrafiltration (UF) is important for survival in peritoneal dialysis. On the other hand, precise and convenient UF measurement suitable for patient daily practice is not as ...

    Authors: Zanzhe Yu, Zhuqing Wang, Qin Wang, Minfang Zhang, Haijiao Jin, Li Ding, Hao Yan, Jiaying Huang, Yan Jin, Simon Davies, Wei Fang and Zhaohui Ni
    Citation: BMC Nephrology 2021 22:382
  5. Alport syndrome (AS), which is a rare hereditary disease caused by mutations of genes including COL4A3, COL4A4 and COL4A5, has a wide spectrum of phenotypes. Most disease-causing variants of AS are located in ...

    Authors: Jing Wu, Jun Zhang, Li Liu, Bo Zhang, Tomohiko Yamamura, Kandai Nozu, Masafumi Matsuo and Jinghong Zhao
    Citation: BMC Nephrology 2021 22:380
  6. Patients with end-stage kidney disease experience serious complications which affect their lives. Few studies have investigated the patients’ quality of life qualitatively from the perspective of family caregi...

    Authors: Sima Sadat Hejazi, Meimanat Hosseini, Abbas Ebadi and Hamid Alavi Majd
    Citation: BMC Nephrology 2021 22:379
  7. The first objective of this study was to determine the relationship between muscle strength or physical performance and mortality, and the second objective was to show the relationship of Geriatric Nutritional...

    Authors: Kenichi Kono, Yoshifumi Moriyama, Hiroki Yabe, Ayaka Hara, Takeki Ishida, Tetsuya Yamada and Yusuke Nishida
    Citation: BMC Nephrology 2021 22:378
  8. Present study was conducted to determine the effect of training on coping efforts and stress moderators, based on transactional model of Lazarus and Folkman, in hemodialysis patients.

    Authors: Mohtasham Ghaffari, Mohammad Ali Morowatisharifabad, Mohammad Saeed Jadgal, Yadollah Mehrabi and Somayeh Alizadeh
    Citation: BMC Nephrology 2021 22:377
  9. There have been cases of minimal change disease (MCD) reported following previous vaccines. During the COVID-19 era, only 3 cases of new-onset MCD and a case of MCD relapse were reported following the Pfizer-B...

    Authors: Shaefiq Thappy, Sherin R. Thalappil, Shahem Abbarh, Abdulrahman Al-Mashdali, Mohammed Akhtar and Mohamad M. Alkadi
    Citation: BMC Nephrology 2021 22:376
  10. Individuals with chronic kidney disease (CKD), hypertension (HTN), or diabetes mellitus (DM) are at increased risk for cardiovascular disease (CVD). The extent to which psychosocial factors are associated with...

    Authors: Nrupen A. Bhavsar, Clemontina A. Davenport, Lexie Zidanyue Yang, Sarah Peskoe, Julia J. Scialla, Rasheeda K. Hall, Crystal C. Tyson, Tara Strigo, Mario Sims, Jane Pendergast, Lesley H. Curtis, L. Ebony Boulware and Clarissa J. Diamantidis
    Citation: BMC Nephrology 2021 22:375
  11. Fibroblast growth factor-23 (FGF23) and α-klotho are associated with anemia in patients with chronic kidney disease. In this post hoc analysis of the ASTRIO study (UMIN000019176), we investigated the relations...

    Authors: Kyoko Ito, Keitaro Yokoyama, Masaaki Nakayama, Masafumi Fukagawa and Hideki Hirakata
    Citation: BMC Nephrology 2021 22:374
  12. Exercise improves health outcomes and quality of life in persons with chronic kidney disease (CKD). The numbers of persons with advanced CKD meeting physical activity guidelines however is low. We undertook a ...

    Authors: Mary Beth Weber, Susan Ziolkowski, Ahad Bootwala, Alan Bienvenida, Shuchi Anand and Felipe Lobelo
    Citation: BMC Nephrology 2021 22:373
  13. To assess the clinical practicability of the ensemble learning model established by Liu et al. in estimating glomerular filtration rate (GFR) and validate whether it is a better model than the Asian modified C...

    Authors: Li Zhao, Jing-jing Zhang, Xin Tian, Jian-min Huang, Peng Xie and Xiang-zhou Li
    Citation: BMC Nephrology 2021 22:372
  14. Acute kidney injury (AKI) incidence is increasing, however AKI is often missed at the emergency department (ED). AKI diagnosis depends on changes in kidney function by comparing a serum creatinine (SCr) measur...

    Authors: Michael Niemantsverdriet, Meriem Khairoun, Ayman El Idrissi, Romy Koopsen, Imo Hoefer, Wouter van Solinge, Jan Willem Uffen, Domenico Bellomo, Wouter Tiel Groenestege, Karin Kaasjager and Saskia Haitjema
    Citation: BMC Nephrology 2021 22:371
  15. It has been suggested that, in patients with CKD stage 5, measured GFR (mGFR), defined as the mean of urea and creatinine clearance, as measured by a 24-h urine collection, is a better measure of renal functio...

    Authors: James G. Heaf, Rafal Yahya and Morten Dahl
    Citation: BMC Nephrology 2021 22:370
  16. Acute kidney injury (AKI) disproportionately affects individuals in low-and middle-income countries (LMIC). However, LMIC—particularly countries in sub-Saharan Africa— are under-represented in global AKI resea...

    Authors: Anthony Batte, Kristin J. Murphy, Ruth Namazzi, Katrina Co, Robert O. Opoka, John M. Ssenkusu, Chandy C. John and Andrea L. Conroy
    Citation: BMC Nephrology 2021 22:369
  17. LncRNA NNT-AS1 (NNT-AS1) has been extensively studied as the causative agent in propagation and progression of lung and bladder cancers, and cholangiocarcinoma. However, its significance in proliferation and i...

    Authors: Zhuang Geng, Xiang Wang, Shiyuan Hao, Bingzi Dong, Yajing Huang, Yangang Wang and Lili Xu
    Citation: BMC Nephrology 2021 22:368
  18. Safety and survival during and after donor nephrectomy (DN) are one of the main concerns in living kidney donors (LKDs). Therefore, kidney (left/right) to be procured should be determined after considering the...

    Authors: Shunta Hori, Nobumichi Tanaka, Tatsuo Yoneda, Nobutaka Nishimura, Mitsuru Tomizawa, Tomonori Nakahama, Yasushi Nakai, Makito Miyake, Kazumasa Torimoto, Kiyoyuki Minamiguchi and Kiyohide Fujimoto
    Citation: BMC Nephrology 2021 22:367
  19. Urine albumin/creatinine ratio (UACR) is an important marker of early renal damage (ERD) caused by hypertension. Recent studies showed that blood pressure was a significant inverse association with temperature...

    Authors: Yuzhuo Zhang, Ying Zhao, Chenglu Wei, Yongrong Li, Hira Aslam, Qingmin Feng, Qing Huang, Yu Zheng, Feifen Lv, Wei Hao and Jike Li
    Citation: BMC Nephrology 2021 22:366
  20. People with kidney failure have a high incidence of major surgery, though the risk of perioperative outcomes at a population-level is unknown. Our objective was to estimate the proportion of people with kidney...

    Authors: Tyrone G. Harrison, Paul E. Ronksley, Matthew T. James, Shannon M. Ruzycki, Marcello Tonelli, Braden J. Manns, Kelly B. Zarnke, Deirdre McCaughey, Prism Schneider, James Wick and Brenda R. Hemmelgarn
    Citation: BMC Nephrology 2021 22:365
  21. Patients on haemodialysis (HD) are often constipated. This study aimed to assess the relationship between constipation and mortality in such patients. In this study, constipation was defined as receiving presc...

    Authors: Yu Honda, Seiji Itano, Aiko Kugimiya, Eiji Kubo, Yosuke Yamada, Miho Kimachi, Yugo Shibagaki and Tatsuyoshi Ikenoue
    Citation: BMC Nephrology 2021 22:363
  22. Few data is available on the risk/benefit balance of native kidney biopsy (KB) in very elderly patients.

    Authors: Mathilde Fedi, Mickaël Bobot, Julia Torrents, Pierre Gobert, Éric Magnant, Yannick Knefati, David Verhelst, Gaëtan Lebrun, Valérie Masson, Philippe Giaime, Julien Santini, Stanislas Bataille, Philippe Brunet, Bertrand Dussol, Stéphane Burtey, Julien Mancini…
    Citation: BMC Nephrology 2021 22:362
  23. Non-communicable diseases (NCDs) are a growing burden which affects every part of the world, including developing countries. Chronic kidney disease (CKD) has varied etiology which can result from or complicate...

    Authors: Candide Tran Ngoc, Prebo Barango, Roger Harrison, Andrew Jones, Steven Velabo Shongwe, Albert Tuyishime, François Uwinkindi, Hongyi Xu and Stephanie Shoop-Worrall
    Citation: BMC Nephrology 2021 22:361
  24. Acute kidney injury (AKI) is common among patients hospitalised with COVID-19 and associated with worse prognosis. The aim of this study was to investigate the epidemiology, risk factors and outcomes of AKI in...

    Authors: Paul D. Jewell, Kate Bramham, James Galloway, Frank Post, Sam Norton, James Teo, Richard Fisher, Rohit Saha, Sam Hutchings, Phil Hopkins, Priscilla Smith, Jennifer Joslin, Satish Jayawardene, Sarah Mackie, Ali Mudhaffer, Amelia Holloway…
    Citation: BMC Nephrology 2021 22:359

    The Correction to this article has been published in BMC Nephrology 2021 22:403

  25. Alport Syndrome and IgA Nephropathy (IgAN) are both disorders that can cause hematuria. Alport syndrome is most commonly an X-linked disease, caused by COL4A5 mutation. Mutations of COL4A3 and COL4A4 on chromo...

    Authors: Aniruddha Bhattacharyya, Yuting Huang, Sarah Hussain Khan, Cinthia Beskow Drachenberg and Laura C. Malone
    Citation: BMC Nephrology 2021 22:358
  26. Kidney failure with replacement therapy and hemodialysis are associated with a decrease in quality of life (QOL). Self-reported QOL symptoms are not always prioritized by the medical team, potentially leading ...

    Authors: Abdallah Guerraoui, Mathilde Prezelin-Reydit, Anne Kolko, Marie Lino-Daniel, Charlotte Dumas de Roque, Pablo Urena, Philippe Chauveau, Catherine Lasseur, Julie Haesebaert and Agnes Caillette-Beaudoin
    Citation: BMC Nephrology 2021 22:357
  27. Xanthogranulomatous pyelonephritis (XGP) is a rare and severe chronic inflammatory disease of the renal parenchyma, which is most commonly associated with super-infections by bacteria such as E. coli, Proteus mir...

    Authors: Zhunan Xu, Tong Cai, Xuebao Zhang, Jitao Wu and Chu Liu
    Citation: BMC Nephrology 2021 22:356
  28. Although the burden of impaired renal function is rising in sub-Saharan Africa (SSA), little is known about correlates of impaired renal function in the region. We determined factors associated with estimated ...

    Authors: Bazil Baltazar Kavishe, Belinda V. Kweka, Dorothea Nitsch, George PrayGod, Kidola Jeremiah, Daniel Faurholt-Jepsen, Suzanne Filteau, Mette Frahm Olsen, Brenda W. Kitilya, Rikke Krogh-Madsen, Henrik Friis and Robert Peck
    Citation: BMC Nephrology 2021 22:355
  29. Trauma is a common cause of acute kidney injury (AKI). Yet little data exist regarding trauma-related-AKI in low-resourced settings, where the majority of deaths from AKI and trauma occur. We prospectively eva...

    Authors: Erica C. Bjornstad, Zachary H. Smith, William Muronya, Charles K. Munthali, Amy K. Mottl, Stephen W. Marshall, Yvonne M. Golightly, Keisha Gibson, Anthony Charles and Emily W. Gower
    Citation: BMC Nephrology 2021 22:354
  30. Galactose-deficient IgA1 (Gd-IgA1) has an increased tendency to form immunocomplexes with IgG in the serum, contributing to IgAN pathogenesis by accumulating in the glomerular mesangium. Several studies showed...

    Authors: Kenan Turgutalp, Egemen Cebeci, Aydin Turkmen, Ulver Derici, Nurhan Seyahi, Necmi Eren, Fatih Dede, Mustafa Gullulu, Taner Basturk, Gulizar Manga Sahin, Murvet Yilmaz, Savas Sipahi, Garip Sahin, Sena Ulu, Erhan Tatar, Ali Gundogdu…
    Citation: BMC Nephrology 2021 22:352
  31. The relationship between growth differentiation factor 15 (GDF-15) and the development of chronic kidney disease (CKD) is still unclear. We sought to examine whether plasma GDF-15 was related to incident CKD a...

    Authors: Xue Bao, Biao Xu, Yan Borné, Marju Orho-Melander, Olle Melander, Jan Nilsson, Anders Christensson and Gunnar Engström
    Citation: BMC Nephrology 2021 22:351
  32. Intravenous iron sucrose is becoming a prevailing treatment for individuals undergoing maintenance haemodialysis, but comparisons of dosing regimens are lacking. The aim of this retrospective review was to eva...

    Authors: Luojin Liu, Huihui Cheng, Yukai Lv, Weiguang Yu, Qilong Liu, Yanqing Wu and Bo Xu
    Citation: BMC Nephrology 2021 22:350
  33. Digoxin is used in patients with chronic heart failure (CHF) who remain symptomatic despite optimal medical treatment. Impaired renal function is commonly associated with CHF. We investigated the relation betw...

    Authors: Parin Shah, Pierpaolo Pellicori, Ian Hanning, Jufen Zhang, Andrew L. Clark and Sunil Bhandari
    Citation: BMC Nephrology 2021 22:349
  34. Patients with kidney failure treated with dialysis or kidney transplantation experience difficulties maintaining employment due to the condition itself and the treatment. We aimed to establish the rate of empl...

    Authors: Lilli Kirkeskov, Rasmus K. Carlsen, Thomas Lund and Niels Henrik Buus
    Citation: BMC Nephrology 2021 22:348
  35. Coronary heart disease due to arteriosclerosis is the leading cause of death in type 1 diabetic patients with end-stage renal disease (ESRD). The aim of this study was to evaluate the effect of simultaneous pa...

    Authors: U. G. Lange, S. Rademacher, B. Zirnstein, R. Sucher, K. Semmling, P. Bobbert, A. A. Lederer, D. Buchloh, L. Seidemann, D. Seehofer, N. Jahn and H.-M. Hau
    Citation: BMC Nephrology 2021 22:347
  36. Mycobacteria avium (M. avium) is a species of ubiquitous slowly growing nontuberculous mycobacteria. It causes opportunistic infections. However, M. avium-related peritonitis in peritoneal dialysis (PD) patients ...

    Authors: Jifang Lu, Zhou Jiang, Ling Wang, Shan Mou and Hao Yan
    Citation: BMC Nephrology 2021 22:345
  37. To describe the long-term hemodialysis arteriovenous fistula (AVF) patency, incidence of AVF use, incidence and nature of AVF complications and surgery in patients after kidney transplantation.

    Authors: Barbara Vajdič Trampuž, Miha Arnol, Jakob Gubenšek, Rafael Ponikvar and Jadranka Buturović Ponikvar
    Citation: BMC Nephrology 2021 22:344
  38. Hyperchloremia is associated with the risks of several morbidities and mortality. However, its relationship with acute kidney injury (AKI) and end-stage renal disease (ESRD) in patients undergoing coronary art...

    Authors: Jae Shin Choi, Donghwan Yun, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Ki Young Na and Seung Seok Han
    Citation: BMC Nephrology 2021 22:343
  39. Peritoneal dialysis (PD) can be associated with abnormal cardiac structure and function and increased mortality risk. Therefore, in this study, we analyzed the cardiac structure and function dynamic changes us...

    Authors: Yunyun Zhu, Difei Zhang, Xiaoxuan Hu, Hui Liu, Yuan Xu, Haijing Hou, Yu Peng, Ying Lu, Xusheng Liu and Fuhua Lu
    Citation: BMC Nephrology 2021 22:342
  40. Healthcare costs related to ESRD are well-described, but broader societal costs of ESRD are less known. This study aimed to estimate patient and family costs, including informal care costs and out-of-pocket co...

    Authors: Eline F. de Vries, Jeanine Los, G. Ardine de Wit and Leona Hakkaart - van Roijen
    Citation: BMC Nephrology 2021 22:341
  41. Cardiovascular diseases (CVD) and infections are recognized as serious complications in patients with end stage kidney disease. However, little is known about the change over time in incidence of these complic...

    Authors: Kamal Preet Kaur, Mavish Safdar Chaudry, Emil Loldrup Fosbøl, Lauge Østergaard, Christian Torp-Pedersen and Niels Eske Bruun
    Citation: BMC Nephrology 2021 22:340
  42. The Japanese Society for Dialysis Therapy (JSDT) published in 2013 inaugural hemodialysis (HD) guidelines. Specific targets include 1.4 for single-pool Kt/V (spKt/V) with a minimum dose of 1.2, minimum dialysi...

    Authors: Tadashi Tomo, Maria Larkina, Ayumi Shintani, Tomonari Ogawa, Bruce M. Robinson, Brian Bieber, Lisa Henn and Ronald L. Pisoni
    Citation: BMC Nephrology 2021 22:339
  43. The use of human intravenous immunoglobulin gamma (IVIG) is associated with thromboembolic events as a complication. There are few reported cases of renal infarction during IVIG use in the general population, ...

    Authors: Eun Woo Choi, Jun Young Do, A. Young Kim and Seok Hui Kang
    Citation: BMC Nephrology 2021 22:338
  44. Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening disease characterized by hyperactivation of the immune system that causes hypercytokinemia and potentially multi organ failure. HLH can o...

    Authors: C. J. Steffen, N. Koch, K. U. Eckardt, K. Amann, E. Seelow and A. Schreiber
    Citation: BMC Nephrology 2021 22:337
  45. Fluid overload and acute kidney injury are common and associated with poor outcomes among critically ill children. The prodrome of renal angina stratifies patients by risk for severe acute kidney injury, but t...

    Authors: Stephen M. Gorga, Erin F. Carlton, Joseph G. Kohne, Ryan P. Barbaro and Rajit K. Basu
    Citation: BMC Nephrology 2021 22:336

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