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  1. Renal hypouricemia (RHUC) is a genetic disorder caused by mutations in the SLC22A12 gene, which encodes the major uric acid (UA) transporter, URAT1. The clinical course of related, living donor-derived RHUC in pa...

    Authors: Kiyokazu Tsuji, Mineaki Kitamura, Kumiko Muta, Yasushi Mochizuki, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Hideki Sakai, Hiroshi Mukae and Tomoya Nishino
    Citation: BMC Nephrology 2020 21:282
    Content type: Case report Published on:

  2. Increased oxidative stress in end-stage renal disease is regarded as one of the important mechanisms in the atherosclerosis and muscle wasting. However, studies examining the clinical significance of oxidative...

    Authors: Young Rim Song, Jwa-Kyung Kim, Hyung-Seok Lee, Sung Gyun Kim and Eun-Kyoung Choi
    Citation: BMC Nephrology 2020 21:281
    Content type: Research article Published on:

  3. Vascular calcification (VC) is well described in large- and medium-sized vessels in patients with chronic kidney disease (CKD), especially in those with end-stage kidney disease (ESKD) on dialysis. Medial calc...

    Authors: Irene Ruderman, Tim D. Hewitson, Edward R. Smith, Stephen G. Holt, Belinda Wigg and Nigel D. Toussaint
    Citation: BMC Nephrology 2020 21:279
    Content type: Research article Published on:

  4. Focal segmental glomerulosclerosis (FSGS) causes renal fibrosis and may lead to kidney failure. FSGS and its common complication, proteinuria, are challenging to treat. Corticosteroids are ineffective in many ...

    Authors: Kyle Hayes, Elizabeth Warner, Chris Bollinger, Dale Wright and Richard M. Fitch
    Citation: BMC Nephrology 2020 21:226
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2020 21:278

  5. Tetralogy of Fallot is the most common cyanotic congenital heart disease. Patients with the condition have a high risk of developing chronic kidney disease. Treatment of kidney disease in patients with complex...

    Authors: Tetsuya Abe, Togo Aoyama, Keiko Sano, Ryoma Miyasaka, Takuya Yamazaki, Yukari Honma, Hiroshi Tominaga, Maoko Ida, Aya Arao, Mayuko Sakakibara, Keiko Hashimoto, Haruka Takahashi, Takeshi Sakai, Shokichi Naito, Toshimi Koitabashi, Takashi Sano…
    Citation: BMC Nephrology 2020 21:277
    Content type: Case report Published on:

  6. Sodium-glucose co-transporter-2 (SGLT-2) inhibitors are a relatively novel class of oral medications for the treatment of Type 2 DM with a generally acceptable safety profile. However, these agents have been a...

    Authors: Erasmia Sampani, Pantelis Sarafidis, Chrysostomos Dimitriadis, Efstratios Kasimatis, Dimitra Daikidou, Konstantinos Bantis, Alexios Papanikolaou and Aikaterini Papagianni
    Citation: BMC Nephrology 2020 21:276
    Content type: Case report Published on:

  7. Erythropoietin-stimulating agents (ESAs) are used to treat anemia in patients with chronic kidney disease, enabling maintenance of stable hemoglobin levels and eliminating the need for multiple transfusions. E...

    Authors: Yasuki Shingu, Tomohiro Nakata, Shinji Sawai, Hisaya Tanaka, Osamu Asai, Keiichi Tamagaki and Kimihiko Nakatani
    Citation: BMC Nephrology 2020 21:275
    Content type: Case report Published on:

  8. Mitochondrial dysfunction contributes to the pathogenesis of diabetic nephropathy (DN). Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role in the transpo...

    Authors: Huanhuan Zhu, Huiting Wan, Lin Wu, Qing Li, Simeng Liu, Suyan Duan, Zhimin Huang, Chengning Zhang, Bo Zhang, Changying Xing and Yanggang Yuan
    Citation: BMC Nephrology 2020 21:274
    Content type: Research article Published on:

  9. Renal infarction (RI) is a rare disease with poor prognosis. Appropriate secondary prevention treatment is essential and requires an exhaustive etiological assessment. We aimed to determine whether invasive en...

    Authors: Fabrice Ivanes, Jean Dewaele, Caroline Touboul, Philippe Gatault, Bénédicte Sautenet, Christelle Barbet, Matthias Büchler, Laurent Quilliet, Denis Angoulvant and Jean-Michel Halimi
    Citation: BMC Nephrology 2020 21:273
    Content type: Research article Published on:

  11. Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, t...

    Authors: Fangfang Xiang, Rongyi Chen, Xuesen Cao, Bo Shen, Xiaohong Chen, Xiaoqiang Ding and Jianzhou Zou
    Citation: BMC Nephrology 2020 21:271
    Content type: Research article Published on:

  12. Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentia...

    Authors: Hewang Lee, Michael B. Fessler, Peng Qu, Jurgen Heymann and Jeffrey B. Kopp
    Citation: BMC Nephrology 2020 21:270
    Content type: Review Published on:

  13. Medical investigation is a favorite application of Ockham’s razor, in virtue of which when presented with competing hypotheses, the solution with the fewest assumptions should be privileged. Hemolytic uremic s...

    Authors: Chloe Schwarz, Alice Brehon, Cyril Mousseaux, Yosu Luque, Patricia Senet, Patricia Mariani, Inna Mohamadou, Lara Zafrani, Véronique Frémeaux-Bacchi, Eric Rondeau, David Buob and Cédric Rafat
    Citation: BMC Nephrology 2020 21:269
    Content type: Case report Published on:

  14. An appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear. We aimed to study the association between vegetarian diets and...

    Authors: Kaijie Xu, Xueying Cui, Bian Wang, Qingya Tang, Jianfang Cai and Xiuhua Shen
    Citation: BMC Nephrology 2020 21:268
    Content type: Research article Published on:

  15. Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis...

    Authors: Bing-Biao Lin, Ming-En Lin, Rong-Hua Huang, Ying-Kai Hong, Bing-Liang Lin and Xue-Jun He
    Citation: BMC Nephrology 2020 21:267
    Content type: Research article Published on:

  16. Setting the dry weight and maintaining fluid balance is still a difficult challenge in dialysis patients. Overhydration is common and associated with increased cardiac morbidity and mortality. Pulmonary hypert...

    Authors: Anne Rudbeck Juhl, Jesper Juul Larsen, Kasper Rossing and Lisbet Brandi
    Citation: BMC Nephrology 2020 21:266
    Content type: Case report Published on:

  17. C3 glomerulonephritis is a recently described entity with heterogeneous histopathological features. This study was conducted to assess the effect of reclassification of C3 glomerulopathies on renal outcomes, m...

    Authors: P. Puri, G. D. Walters, M. N. Fadia, M. Konia, K. A. Gibson and S. H. Jiang
    Citation: BMC Nephrology 2020 21:265
    Content type: Research article Published on:

  18. Haemodialysis (HD) patients are burdened by frequent fluid shifts which amplify their comorbidities. Bioimpedance (bioZ) is a promising technique to monitor changes in fluid status. The aim of this study is to...

    Authors: Melanie K. Schoutteten, Julie Vranken, Seulki Lee, Christophe J. P. Smeets, Hélène De Cannière, Chris Van Hoof, Jacques Peeters, Willemijn Groenendaal and Pieter M. Vandervoort
    Citation: BMC Nephrology 2020 21:264
    Content type: Technical advance Published on:

  19. The currently available data with respect to the association between vitamin D receptor (VDR) gene polymorphism and risk to urolithiasis are inconclusive and inconsistent. Hence, an exhaustive meta-analysis can s...

    Authors: Danyal Imani, Bahman Razi, Arezou Khosrojerdi, Kaivan Lorian, Morteza Motallebnezhad, Ramazan Rezaei and Saeed Aslani
    Citation: BMC Nephrology 2020 21:263
    Content type: Research article Published on:

  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ylenia Ingrasciotta, Viviana Lacava, Ilaria Marcianò, Francesco Giorgianni, Giovanni Tripepi, Graziella D’. Arrigo, Alessandro Chinellato, Daniele Ugo Tari, Domenico Santoro and Gianluca Trifirò
    Citation: BMC Nephrology 2020 21:262
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2019 20:359

  21. Patients receiving chronic hemodialysis treatments are at a higher risk of fracture compared to the general population. While the use of heparin during dialysis is crucial to avoid thrombosis of the extracorpo...

    Authors: Hind Harrak, Emilie René, Noor Alsalemi, Naoual Elftouh and Jean-Philippe Lafrance
    Citation: BMC Nephrology 2020 21:261
    Content type: Research article Published on:

  22. The seroprevalence of human Parvovirus B19 (PVB19) is 70–85% in adults worldwide. PVB19 is the etiologic agent of the fifth disease, is a cause of aplastic anemia, and can be associated with kidney injury. We ...

    Authors: Maëlis Kauffmann, Mickaël Bobot, Laurent Daniel, Julia Torrents, Yannick Knefati, Olivier Moranne, Stéphane Burtey, Christine Zandotti and Noémie Jourde-Chiche
    Citation: BMC Nephrology 2020 21:260
    Content type: Research article Published on:

  23. The impact of anemia treatment with erythropoietin stimulating agents (ESA) on health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients is controversial, particularly regarding optimal h...

    Authors: Murilo Guedes, Camila R. Guetter, Lucas H. O. Erbano, Andre G. Palone, Jarcy Zee, Bruce M. Robinson, Ronald Pisoni, Thyago Proença de Moraes, Roberto Pecoits-Filho and Cristina P. Baena
    Citation: BMC Nephrology 2020 21:259
    Content type: Research article Published on:

  24. Lupus nephritis is associated with increased risk of end-stage renal disease (ESRD) and all-cause mortality. We evaluated the clinical features and outcomes of patients with early and delayed lupus nephritis.

    Authors: Sung Soo Ahn, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee
    Citation: BMC Nephrology 2020 21:258
    Content type: Research article Published on:

  25. Secondary hyperparathyroidism (SHPT) is a common high-risk factor for mortality in end-stage renal disease, and parathyromatosis and supernumerary parathyroid glands are very rare causes of persistent SHPT. Pr...

    Authors: Jun Yang, Jun Zhang, Ning-hu Liu, Hao Liu and Meng-jie Dong
    Citation: BMC Nephrology 2020 21:257
    Content type: Case report Published on:

  26. Renal loss of potassium (K+) and magnesium (Mg2+) in salt losing tubulopathies (SLT) leads to significantly reduced Quality of Life (QoL) and higher risks of cardiac arrhythmia. The normalization of K+ is current...

    Authors: Michael Eder, Elisabeth Darmann, Maria C. Haller, Marija Bojic, Markus Peck-Radosavljevic, Rainer Huditz, Gregor Bond, Andreas Vychytil, Roman Reindl-Schwaighofer and Željko Kikić
    Citation: BMC Nephrology 2020 21:256
    Content type: Research article Published on:

  27. In recent years, the diagnostic utility of urinary protein levels has been demonstrated for the early detection and progression of kidney disease. This study aimed to evaluate the associations of the non-album...

    Authors: Khalid Siddiqui, Salini Scaria Joy, Shaik Sarfaraz Nawaz, Dhekra Alnaqeb, Muhammad Mujammami and Khalid Al-Rubeaan
    Citation: BMC Nephrology 2020 21:255
    Content type: Research article Published on:

  28. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Currie Moore, Lesley-Anne Carter, Sandip Mitra, Suzanne Skevington and Alison Wearden
    Citation: BMC Nephrology 2020 21:254
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2020 21:185

  29. Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1...

    Authors: Mohammad Abuzeineh, Amtul Aala, Sami Alasfar and Nada Alachkar
    Citation: BMC Nephrology 2020 21:253
    Content type: Research article Published on:

  30. According to the “lipid nephrotoxicity hypothesis”, there is now significant research being conducted in this area. By studying the role of hyperlipidemia in chronic kidney disease in the general Zhejiang popu...

    Authors: Xudong Liang, Meiyu Ye, Mei Tao, Danna Zheng, Ruyi Cai, Yifan Zhu, Juan Jin and Qiang He
    Citation: BMC Nephrology 2020 21:252
    Content type: Research article Published on:

  31. The occurrences of hyperuricemia and acute kidney injury after antithymocyte globulin treatment are unusual in kidney transplant recipients. Here, we report a unique case of acute kidney injury with extreme hy...

    Authors: Yohan Park, Byung Ha Chung, Cheol Whee Park, Yong-Soo Kim and Chul Woo Yang
    Citation: BMC Nephrology 2020 21:251
    Content type: Case report Published on:

  32. Access to kidney transplantation by uremic children is very limited due to the lack of donors in many countries. We sought to explore small pediatric kidney donors as a strategy to provide transplant opportuni...

    Authors: Xiaojun Su, Wenjun Shang, Longshan Liu, Jun Li, Qian Fu, Yonghua Feng, Huanxi Zhang, Ronghai Deng, Chenglin Wu, Zhigang Wang, Xinlu Pang, Björn Nashan, Guiwen Feng and Changxi Wang
    Citation: BMC Nephrology 2020 21:250
    Content type: Research article Published on:

  33. Renal replacement therapy (RRT) places a burden on patients, and geographical relocation for easier access to healthcare facilities is a necessity for some. Incidence and factors associated with relocation has...

    Authors: Hicham I Cheikh Hassan, Jenny HC Chen and Karumathil Murali
    Citation: BMC Nephrology 2020 21:249
    Content type: Research article Published on:

  35. The 2016 Oxford Classification’s MEST-C scoring system predicts outcomes in adults with IgA nephropathy (IgAN), but it lacks tremendous cohort validation in children with IgAN in China. We sought to verify whe...

    Authors: Heyan Wu, Zhengkun Xia, Chunlin Gao, Pei Zhang, Xiao Yang, Ren Wang, Meiqiu Wang and Yingchao Peng
    Citation: BMC Nephrology 2020 21:247
    Content type: Research article Published on:

  37. Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney an...

    Authors: Rachael D. Wright, Fariba Bannerman, Michael W. Beresford and Louise Oni
    Citation: BMC Nephrology 2020 21:245
    Content type: Research article Published on:

  38. Several studies have reported that lower body mass index (BMI) is associated with high mortality in patients with chronic kidney disease (CKD). Rate of infection-related death in CKD patients is increasing. Ho...

    Authors: Tae Yamamoto, Masaaki Nakayama, Mariko Miyazaki, Hiroshi Sato, Masato Matsushima, Toshinobu Sato and Sadayoshi Ito
    Citation: BMC Nephrology 2020 21:244
    Content type: Research article Published on:

  39. To explore the potential value of three-dimensional ultrasonography (3DUS) and contrast-enhanced ultrasound (CEUS) in the diagnosis of diabetic nephropathy (DN) in Chinese diabetic patients with kidney injury.

    Authors: Nan Li, Yi-ru Wang, Xiao-qi Tian, Lin Lin, Shu-yuan Liang, Qiu-yang Li, Xiang Fei, Jie Tang and Yu-kun Luo
    Citation: BMC Nephrology 2020 21:243
    Content type: Research article Published on:

  40. Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but th...

    Authors: Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball…
    Citation: BMC Nephrology 2020 21:242
    Content type: Study protocol Published on:

  41. Constrictive pericarditis is easily overlooked and can lead to severe problems in hemodynamics and end-organ perfusion, in our patient leading to 98 days of anuria after living kidney transplantation. This was...

    Authors: Caroline Wacker, Michael Weyand, Mario Schiffer and Mirian Opgenoorth
    Citation: BMC Nephrology 2020 21:241
    Content type: Case report Published on:

  42. Preeclampsia (PE) refers to the development of hypertension and new-onset proteinuria or progressive organ damage (especially kidney) in a previously normotensive pregnant women after 20 weeks of gestation. Th...

    Authors: Tomo Suzuki, Daisuke Ichikawa, Mayumi Nakata, Shiika Watanabe, Wei Han, Kaori Kohatsu, Sayuri Shirai, Naohiko Imai, Junki Koike and Yugo Shibagaki
    Citation: BMC Nephrology 2020 21:240
    Content type: Case report Published on:

  43. Dialysis patients have a high pill burden, increasing their care complexity. A previous study in our institution’s dialysis unit found notable discrepancies between medication prescriptions, purchases and pati...

    Authors: Lee Gilad, Yosef S. Haviv, Inbal Cohen-Glickman, David Chinitz and Matan J. Cohen
    Citation: BMC Nephrology 2020 21:239
    Content type: Research article Published on:

  45. This study aimed to ascertain whether the correlation of high serum ferritin with mortality is affected by systemic inflammation and to investigate the optimal serum ferritin level for predicting death when in...

    Authors: Sha Fu, Junzhe Chen, Bo Liu, Peifen Liang, Yuchun Zeng, Min Feng, Zhenjian Xu, Guiqiong Zheng, Suqiong Yang, Anping Xu and Ying Tang
    Citation: BMC Nephrology 2020 21:237
    Content type: Research article Published on:

  46. Atypical hemolytic uremic syndrome (aHUS) is a life-threatening disease that leads to end-stage kidney disease if only a poor response to plasma exchanges (PEs) or eculizumab therapy is achieved.

    Authors: Yusuke Kuroki, Koji Mitsuiki, Kaneyasu Nakagawa, Kazuhiko Tsuruya, Ritsuko Katafuchi, Hideki Hirakata and Toshiaki Nakano
    Citation: BMC Nephrology 2020 21:236
    Content type: Case report Published on:

  47. Sarcoidosis is a multisystem inflammatory disorder and can affect any organ; however, ureteric involvement is extremely rare with only four cases reported in the literature to date, all of which were diagnosed...

    Authors: Michikata Hayashida, Akihiro Yano, Kiichi Hagiwara, Shoichi Nagamoto, Kohei Ogawa, Kazushige Sakaguchi, Naoki Sawa, Toshikazu Okaneya and Shinji Urakami
    Citation: BMC Nephrology 2020 21:235
    Content type: Case report Published on:

  48. Previous studies have not described the relationship between reducing radial artery diameter as well as increasing age and functional maturation of the radio-cephalic arteriovenous fistula (RCAVF) and no data ...

    Authors: Zi-ming Wan, Bo Hu, Qi-quan Lai, Xue-jing Gao, Bo Tu, Yu Zhou and Wen-bo Zhao
    Citation: BMC Nephrology 2020 21:234
    Content type: Research article Published on:

  49. Arteriosclerosis is prevalent in patients with chronic kidney disease (CKD). Our aims were to investigate (1) the effects of 12 months of either balance- or strength- both in combination with endurance trainin...

    Authors: Yunan Zhou, Matthias Hellberg, Thomas Hellmark, Peter Höglund and Naomi Clyne
    Citation: BMC Nephrology 2020 21:233
    Content type: Research article Published on:

  50. There is an increasing burden of non-communicable disease globally. Tenofovir disoproxil fumarate (TDF) is the most commonly prescribed antiretroviral drug globally. Studies show that patients receiving TDF ar...

    Authors: Louis Nyende, Robert Kalyesubula, Emmanuel Sekasanvu and Pauline Byakika-Kibwika
    Citation: BMC Nephrology 2020 21:232
    Content type: Research article Published on:
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BMC Nephrology

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