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  1. Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a “cruel alliance”, with CVD responsible for about half of all deaths among CKD patients. Chronic k...

    Authors: S. O. Oguntola, M. O. Hassan, R. Duarte, A. Vachiat, P. Manga and S. Naicker
    Citation: BMC Nephrology 2019 20:399
    Content type: Research article Published on:

  2. Patients with chronic kidney disease (CKD) have a high prevalence of cardiovascular diseases, which often lead to physical inactivity that correlates with CKD exacerbation. The benefits of regular exercise to ...

    Authors: Lijun Zhang, Yangyang Wang, Lianlian Xiong, Yanfang Luo, Zhijun Huang and Bin Yi
    Citation: BMC Nephrology 2019 20:398
    Content type: Research article Published on:

  4. Elevated serum phosphorus concentrations are common among maintenance hemodialysis patients. Protein is a major source of dietary phosphate, but restriction of protein intake can result in hypoalbuminemia and ...

    Authors: Kamyar Kalantar-Zadeh, Linda H. Ficociello, Vidhya Parameswaran, Nicolaos V. Athienites, Claudy Mullon, Robert J. Kossmann and Daniel W. Coyne
    Citation: BMC Nephrology 2019 20:396
    Content type: Research article Published on:

  5. Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of ...

    Authors: Nishank Jain, Fei Wan, Monica Kothari, Anuoluwapo Adelodun, Jerry Ware, Ravi Sarode and S. Susan Hedayati
    Citation: BMC Nephrology 2019 20:395
    Content type: Research article Published on:

  6. Sebaceous carcinoma is a rare but progressive malignant skin cancer, and the incidence is approximately five times higher in post-transplant patients than in people who have not received kidney transplants. Se...

    Authors: Masahiro Tomonari, Mariko Shimada, Yasuyuki Nakada, Izumi Yamamoto, Munenari Itoh, Yusuke Koike, Akimitsu Kobayashi, Jun Miki, Hiroki Yamada, Takahiro Kimura, Shinya Saito, Kokichi Sugano, Shigeki Sekine, Hiroyasu Yamamoto, Akihiko Asahina and Takashi Yokoo
    Citation: BMC Nephrology 2019 20:394
    Content type: Case report Published on:

  7. Preliminary studies have shown the potential use of salivary creatinine concentration in the diagnosis of chronic kidney disease (CKD). For saliva to replace serum as a diagnostic tool, studies must be done to...

    Authors: Dada Oluwaseyi Temilola, Karla Bezuidenhout, Rajiv Timothy Erasmus, Lawrence Stephen, Mogamat Razeen Davids and Haly Holmes
    Citation: BMC Nephrology 2019 20:387
    Content type: Research article Published on:

  8. Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathoph...

    Authors: Eduardo De la Cruz-Cano, Cristina del C. Jiménez-González, Vicente Morales-García, Conny Pineda-Pérez, Juan G. Tejas-Juárez, Francisco J. Rendón-Gandarilla, Silvia Jiménez-Morales and José A. Díaz-Gandarilla
    Citation: BMC Nephrology 2019 20:393
    Content type: Research article Published on:

  9. Online hemodiafiltration (OL-HDF) is associated with better removal of both small and middle molecules and might improve survival compared to conventional hemodialysis (HD). Nevertheless, hemodiafiltration (HD...

    Authors: Charles Cuvelier, Michel Tintillier, Gabriela Migali, Charlotte Van Ende and Jean-Michel Pochet
    Citation: BMC Nephrology 2019 20:392
    Content type: Case report Published on:

  10. Cell-free deoxyribonucleic acid DNA (cf-DNA) in urine is promising due to the advantage of urine as an easily obtained and non-invasive sample source over tissue and blood. In clinical practice, it is importan...

    Authors: Chia-Chu Chang, Ping-Fang Chiu, Chia-Lin Wu, Cheng-Ling Kuo, Ching-Shan Huang, Chin-San Liu and Ching-Hui Huang
    Citation: BMC Nephrology 2019 20:391
    Content type: Research article Published on:

  11. Neuropsychiatric conditions such as depression, delirium and cognitive impairment are common in patients with end-stage kidney disease (ESKD) and individuals suffering from ESKD are more likely to commit suici...

    Authors: Pierre Antoine Brown, Peter O. Magner, Swapnil Hiremath and Edward G. Clark
    Citation: BMC Nephrology 2019 20:390
    Content type: Case report Published on:

  12. Some people who are receiving dialysis treatment have virus infection such as hepatitis B, hepatitis C and/or HIV that is present in their blood. These infections can be transmitted to other patients if blood ...

    Authors: Elizabeth Garthwaite, Veena Reddy, Sam Douthwaite, Simon Lines, Kay Tyerman and James Eccles
    Citation: BMC Nephrology 2019 20:388
    Content type: Guidelines Published on:

  13. Liddle syndrome is a monogenic disease with autosomal dominant inheritance. Basic characteristics of this disease are hypertension, reduced concentration of aldosterone and renin activity, as well as increased...

    Authors: Anastasiya A. Kozina, Tatiana A. Trofimova, Elena G. Okuneva, Natalia V. Baryshnikova, Varvara A. Obuhova, Anna Yu. Krasnenko, Kirill Yu. Tsukanov, Olesya I. Klimchuk, Ekaterina I. Surkova, Peter A. Shatalov and Valery V. Ilinsky
    Citation: BMC Nephrology 2019 20:389
    Content type: Case report Published on:

  14. Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) often develop hypertension in childhood or early adulthood. Although this could result in left ventricular hypertrophy (LVH), a major risk fac...

    Authors: Huanwen Chen, Terry Watnick, Susie N. Hong, Barry Daly, Yongfang Li and Stephen L. Seliger
    Citation: BMC Nephrology 2019 20:386
    Content type: Research article Published on:

  15. Conservative management, an approach to treating end-stage kidney disease without dialysis, while generally associated with shorter life expectancy than treatment with dialysis, is associated with fewer hospit...

    Authors: Melissa W. Wachterman, Tarikwa Leveille, Nancy L. Keating, Steven R. Simon, Sushrut S. Waikar and Barbara Bokhour
    Citation: BMC Nephrology 2019 20:385
    Content type: Research article Published on:

  17. Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysf...

    Authors: Li Zhang, Qing-shan Ma, Yan Zhang, Bai-chao Sun and Leng-yue Zhao
    Citation: BMC Nephrology 2019 20:383
    Content type: Case report Published on:

  19. Background: The pathological findings of tonsils in IgA nephropathy include the expansion of T-cell nodules around lymphoid follicles and abnormal reticulation of the crypt epithelium in contrast to chronic to...

    Authors: Takuji Enya, Tomoki Miyazawa, Kohei Miyazaki, Rina Oshima, Yuichi Morimoto, Mitsuru Okada, Tsukasa Takemura and Keisuke Sugimoto
    Citation: BMC Nephrology 2019 20:381
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Nephrology 2024 25:110

  20. Cancer in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. Cancer can be a cause or an effect of CKD. In CKD patients, a better understanding of cancer di...

    Authors: Rajkumar Chinnadurai, Emma Flanagan, Gordon C. Jayson and Philip A. Kalra
    Citation: BMC Nephrology 2019 20:380
    Content type: Research article Published on:

  21. This guideline is written primarily for doctors and nurses working in dialysis units and related areas of medicine in the UK, and is an update of a previous version written in 2009. It aims to provide guidance...

    Authors: Damien Ashby, Natalie Borman, James Burton, Richard Corbett, Andrew Davenport, Ken Farrington, Katey Flowers, James Fotheringham, R. N. Andrea Fox, Gail Franklin, Claire Gardiner, R. N. Martin Gerrish, Sharlene Greenwood, Daljit Hothi, Abdul Khares, Pelagia Koufaki…
    Citation: BMC Nephrology 2019 20:379
    Content type: Guidelines Published on:

  22. The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health sys...

    Authors: Francis F. Furia, Jacqueline Shoo, Paschal J. Ruggajo, Kajiru Kilonzo, Gopal Basu, Karen Yeates, Santosh Varughese, Einar Svarstad and Onesmo Kisanga
    Citation: BMC Nephrology 2019 20:378
    Content type: Research article Published on:

  24. Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys. Overall, it is thought to be non-pathoge...

    Authors: Vivian W. Y. Leung, Sarah-Jeanne Pilon, Pierre O. Fiset and Shaifali Sandal
    Citation: BMC Nephrology 2019 20:376
    Content type: Case report Published on:

  25. TAFRO syndrome is a systemic inflammatory disorder that manifests as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Renal dysfunction is frequently complicated wit...

    Authors: Yoshikuni Nagayama, Mizuki Yamano, Motoka Yagame, Tomoyuki Nariyama, Mikiko Takahashi, Masashi Kawamoto and Katsuyuki Matsui
    Citation: BMC Nephrology 2019 20:375
    Content type: Case report Published on:

  26. Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered.

    Authors: Chun-Yuan Hsiao, Chip Gresham and Mark R. Marshall
    Citation: BMC Nephrology 2019 20:374
    Content type: Case report Published on:

  27. Medication non-adherence is a risk factor for acute kidney transplant rejection. The association of non-adherence with short-term allograft loss in patients who develop acute rejection and are subsequently tre...

    Authors: Ahmed Al-Sheyyab, Laura Binari, Mohammed Shwetar, Everly Ramos, Meghan E. Kapp, Stefanie Bala, Nikita Wilson, Rachel C. Forbes, J. Harold Helderman, Khaled Abdel-Kader and Beatrice P. Concepcion
    Citation: BMC Nephrology 2019 20:373
    Content type: Research article Published on:

  28. Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD) in both dialysis and nondialysis patients. In clini...

    Authors: Christine K. Bailey, Stephen Caltabiano, Alexander R. Cobitz, Chun Huang, Kelly M. Mahar and Vickas V. Patel
    Citation: BMC Nephrology 2019 20:372
    Content type: Research article Published on:

  29. This study was undertaken to compare the accuracy of chronic kidney disease-epidemiology collaboration (eGFRCKD-EPI) to modification of diet in renal disease (eGFRMDRD) and the Cockcroft-Gault formulas of Creatin...

    Authors: Sandro Gelsomino, Massimo Bonacchi, Fabiana Lucà, Fabio Barili, Stefano Del Pace, Orlando Parise, Daniel M. Johnson and Michele Massimo Gulizia
    Citation: BMC Nephrology 2019 20:371
    Content type: Research article Published on:

  31. Numerous studies have evaluated the prevalence and importance of mineral and bone disorders among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, little is known about d...

    Authors: Tianye Yang, Wenji Wang, Xiao Tang, Peng Shi, Lulu Zhang, Wenyan Yu, Yingxin Xie, Daqiao Guo and Feng Ding
    Citation: BMC Nephrology 2019 20:369
    Content type: Research article Published on:

  32. Acute kidney injury (AKI), which may progress to end-stage kidney disease (ESKD), is a potential complication of aortic dissection. Notably, in all reported ESKD cases secondary to aortic dissection, imaging e...

    Authors: Yoshihiro Mukaiyama, Akira Okada, Yutaro Kawakatsu, Satoshi Akuzawa, Kazuchika Suzuki, Naoyuki Ishigami and Tatsuo Yamamoto
    Citation: BMC Nephrology 2019 20:368
    Content type: Case report Published on:

  33. Acute kidney injury (AKI) is a common complication in patients undergoing liver transplant (LT) and is associated with high morbidity and mortality. We aim to evaluate the pattern of urine and plasma neutrophi...

    Authors: Camila Lima, Luciana Bertocco de Paiva Haddad, Patrícia Donado Vaz de Melo, Luiz Marcelo Malbouisson, Lilian Pires Freitas do Carmo, Luiz Augusto Carneiro D’Albuquerque and Etienne Macedo
    Citation: BMC Nephrology 2019 20:367
    Content type: Research article Published on:

  34. Immune Checkpoint Inhibitors (ICPIs) are promising new drugs in treatment of advanced tumours targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD1) or its ligand (PDL-1)...

    Authors: Mathilde Lemoine, Baptiste Dilly, Alexandre Curie, Vivien Hébert, Charlotte Laurent, Mélanie Hanoy, Steven Grangé, Dominique Guerrot, Arnaud François and Dominique Bertrand
    Citation: BMC Nephrology 2019 20:366
    Content type: Case report Published on:

  35. Kidney transplantation is considered to be the treatment of choice for people with end-stage renal disease (ESRD). However, due to the shortage of available organs and the increase in the ESRD prevalence in Eu...

    Authors: M. Lorent, Y. Foucher, K. Kerleau, S. Brouard, C. Baayen, S. Lebouter, M. Naesens, O. Bestard Matamoros, A. Åsberg and M. Giral
    Citation: BMC Nephrology 2019 20:365
    Content type: Database Published on:

  36. Chronic allograft damage (CAD) is the leading cause of long-term graft dysfunction. A noninvasive method that can diagnose CAD early and monitor its development is needed.

    Authors: Qiang Zhang, Zexing Yu, Song Zeng, Lu Liang, Yue Xu, Zijian Zhang, Hao Tang, Wenjiao Jiao, Wenrui Xue, Wei Wang, Xiaodong Zhang, Tao Jiang and Xiaopeng Hu
    Citation: BMC Nephrology 2019 20:364
    Content type: Research article Published on:

  37. Patients receiving maintenance hemodialysis (HD) and peritoneal dialysis (PD) are frequently hospitalized. Reducing unplanned 30-day hospital readmissions is a key priority for improving the quality of health ...

    Authors: Yu Lin, Chao Yang, Hong Chu, Jingyi Wu, Ke Lin, Ying Shi, Haibo Wang, Guilan Kong and Luxia Zhang
    Citation: BMC Nephrology 2019 20:363
    Content type: Research article Published on:

  38. Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatem...

    Authors: Hongran Moon, Ho Jun Chin, Ki Young Na, Kwon Wook Joo, Yon Su Kim, Sejoong Kim and Seung Seok Han
    Citation: BMC Nephrology 2019 20:362
    Content type: Research article Published on:

  39. More than 6200 End Stage Renal Disease patients in the Netherlands are dependent on dialysis, either performed at home or in a dialysis centre. Visiting a dialysis centre three times a week is considered a lar...

    Authors: A. van Eck van der Sluijs, A. A. Bonenkamp, F. W. Dekker, A. C. Abrahams and B. C. van Jaarsveld
    Citation: BMC Nephrology 2019 20:361
    Content type: Study protocol Published on:

  40. The diagnostic value of serum M-type phospholipase A2 receptor antibody (sPLA2R-ab) expression in patients with primary membranous nephropathy (PMN) has been established. However, the association between sPLA2...

    Authors: Yufeng Liang, Jianxin Wan, Yongping Chen and Yangbin Pan
    Citation: BMC Nephrology 2019 20:360
    Content type: Research article Published on:

  41. Evidences show that around 20% of biosimilar or originator erythropoiesis-stimulating agents (ESAs) users are hyporesponsive. Controversial post-marketing data exist on the predictors of ESA hyporesponsiveness...

    Authors: Ylenia Ingrasciotta, Viviana Lacava, Ilaria Marcianò, Francesco Giorgianni, Giovanni Tripepi, Graziella D’ Arrigo, Alessandro Chinellato, Daniele Ugo Tari, Domenico Santoro and Gianluca Trifirò
    Citation: BMC Nephrology 2019 20:359
    Content type: Research article Published on:

  42. Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional pro...

    Authors: Ruifang Xiong, Xiangxue Lu, Jinghong Song, Han Li and Shixiang Wang
    Citation: BMC Nephrology 2019 20:358
    Content type: Research article Published on:

  43. Chronic kidney disease (CKD) is often under-recognized and poorly documented via diagnoses, but the extent of under-recognition is not well understood among Medicare beneficiaries. The current study used claim...

    Authors: Clarissa J. Diamantidis, Sarah L. Hale, Virginia Wang, Valerie A. Smith, Sarah Hudson Scholle and Matthew L. Maciejewski
    Citation: BMC Nephrology 2019 20:357
    Content type: Research article Published on:

  44. Pulsatility is an important property of hemodialysis arteriovenous fistulas (AVF) and can be perceived by the fingers as a gradual decrease in strength downstream from the anastomosis along the main trunk of t...

    Authors: Matt Chiung-Yu Chen, Mei-Jui Weng, Misoso Yi-Wen Wu, Yi-Chun Liu and Wen-Che Chi
    Citation: BMC Nephrology 2019 20:356
    Content type: Research article Published on:

  45. Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical mani...

    Authors: Riccardo Magistroni, Alessandra Mangolini, Sonia Guzzo, Francesca Testa, Mario R. Rapanà, Renzo Mignani, Giorgia Russo, Francesco di Virgilio and Gianluca Aguiari
    Citation: BMC Nephrology 2019 20:355
    Content type: Research article Published on:

  46. Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB) usage,...

    Authors: Sehoon Park, Chung Hee Baek, Heounjeong Go, Young Hoon Kim, Sang–il Min, Jongwon Ha, Yong Chul Kim, Jung Pyo Lee, Yon Su Kim, Kyung Chul Moon, Su-Kil Park and Hajeong Lee
    Citation: BMC Nephrology 2019 20:354
    Content type: Research article Published on:

  47. 17q12 deletion syndrome encompasses a broad constellation of clinical phenotypes, including renal magnesium wasting, maturity-onset diabetes of the young (MODY), renal cysts, genitourinary malformations, and n...

    Authors: Howard J. Li, Catherine Groden, Melanie P. Hoenig, Evan C. Ray, Carlos R. Ferreira, Willam Gahl and Danica Novacic
    Citation: BMC Nephrology 2019 20:353
    Content type: Case report Published on:

  48. Tacrolimus (TAC) is effective in treating membranous nephropathy (MN); however relapses are frequent after treatment cessation. We conducted a randomised controlled trial to examine whether the addition of myc...

    Authors: Aikaterini Nikolopoulou, Marie Condon, Tabitha Turner-Stokes, H. Terence Cook, Neill Duncan, Jack W. Galliford, Jeremy B. Levy, Liz Lightstone, Charles D. Pusey, Candice Roufosse, Thomas D. Cairns and Megan E. Griffith
    Citation: BMC Nephrology 2019 20:352
    Content type: Research article Published on:

  49. Spironolactone can improve endothelial dysfunction in the setting of heart failure and diabetes models. However, its beneficial effect in the cardiovascular system is not clear in the setting of non-diabetic r...

    Authors: Chun-Cheng Wang, An-Sheng Lee, Shu-Hui Liu, Kuan-Cheng Chang, Ming-Yi Shen and Chiz-Tzung Chang
    Citation: BMC Nephrology 2019 20:351
    Content type: Research article Published on:
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BMC Nephrology

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