BMC Nephrology is affiliated with the UK Kidney Association
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Page 42 of 91
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Citation: BMC Nephrology 2019 20:401
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Atherosclerotic vascular disease is more prevalent among black ESKD patients on long-term CAPD in South Africa
Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a “cruel alliance”, with CVD responsible for about half of all deaths among CKD patients. Chronic k...
Citation: BMC Nephrology 2019 20:399 -
Exercise therapy improves eGFR, and reduces blood pressure and BMI in non-dialysis CKD patients: evidence from a meta-analysis
Patients with chronic kidney disease (CKD) have a high prevalence of cardiovascular diseases, which often lead to physical inactivity that correlates with CKD exacerbation. The benefits of regular exercise to ...
Citation: BMC Nephrology 2019 20:398 -
Glycemia affects glomerular filtration rate in people with type 2 diabetes
In type 2 diabetes (T2DM), the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation for estimated glomerular filtration rate (eGFR) systematically underestimates the measured adjusted glomerula...
Citation: BMC Nephrology 2019 20:397 -
Changes in serum albumin and other nutritional markers when using sucroferric oxyhydroxide as phosphate binder among hemodialysis patients: a historical cohort study
Elevated serum phosphorus concentrations are common among maintenance hemodialysis patients. Protein is a major source of dietary phosphate, but restriction of protein intake can result in hypoalbuminemia and ...
Citation: BMC Nephrology 2019 20:396 -
Association of platelet function with depression and its treatment with sertraline in patients with chronic kidney disease: analysis of a randomized trial
Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of ...
Citation: BMC Nephrology 2019 20:395 -
Muir–Torre syndrome: sebaceous carcinoma concurrent with colon cancer in a kidney transplant recipient; a case report
Sebaceous carcinoma is a rare but progressive malignant skin cancer, and the incidence is approximately five times higher in post-transplant patients than in people who have not received kidney transplants. Se...
Citation: BMC Nephrology 2019 20:394 -
Salivary creatinine as a diagnostic tool for evaluating patients with chronic kidney disease
Preliminary studies have shown the potential use of salivary creatinine concentration in the diagnosis of chronic kidney disease (CKD). For saliva to replace serum as a diagnostic tool, studies must be done to...
Citation: BMC Nephrology 2019 20:387 -
Arg913Gln variation of SLC12A3 gene is associated with diabetic nephropathy in type 2 diabetes and Gitelman syndrome: a systematic review
Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathoph...
Citation: BMC Nephrology 2019 20:393 -
Albumin losses during hemodiafiltration: all dialyzers are not created equal - a case report
Online hemodiafiltration (OL-HDF) is associated with better removal of both small and middle molecules and might improve survival compared to conventional hemodialysis (HD). Nevertheless, hemodiafiltration (HD...
Citation: BMC Nephrology 2019 20:392 -
Urinary cell-free mitochondrial and nuclear deoxyribonucleic acid correlates with the prognosis of chronic kidney diseases
Cell-free deoxyribonucleic acid DNA (cf-DNA) in urine is promising due to the advantage of urine as an easily obtained and non-invasive sample source over tissue and blood. In clinical practice, it is importan...
Citation: BMC Nephrology 2019 20:391 -
Death due to delirium: a case of a self-cut hemodialysis dialysis catheter - a case report
Neuropsychiatric conditions such as depression, delirium and cognitive impairment are common in patients with end-stage kidney disease (ESKD) and individuals suffering from ESKD are more likely to commit suici...
Citation: BMC Nephrology 2019 20:390 -
Clinical practice guideline management of blood borne viruses within the haemodialysis unit
Some people who are receiving dialysis treatment have virus infection such as hepatitis B, hepatitis C and/or HIV that is present in their blood. These infections can be transmitted to other patients if blood ...
Citation: BMC Nephrology 2019 20:388 -
Liddle syndrome due to a novel mutation in the γ subunit of the epithelial sodium channel (ENaC) in family from Russia: a case report
Liddle syndrome is a monogenic disease with autosomal dominant inheritance. Basic characteristics of this disease are hypertension, reduced concentration of aldosterone and renin activity, as well as increased...
Citation: BMC Nephrology 2019 20:389 -
Left ventricular hypertrophy in a contemporary cohort of autosomal dominant polycystic kidney disease patients
Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD) often develop hypertension in childhood or early adulthood. Although this could result in left ventricular hypertrophy (LVH), a major risk fac...
Citation: BMC Nephrology 2019 20:386 -
Nephrologists’ emotional burden regarding decision-making about dialysis initiation in older adults: a qualitative study
Conservative management, an approach to treating end-stage kidney disease without dialysis, while generally associated with shorter life expectancy than treatment with dialysis, is associated with fewer hospit...
Citation: BMC Nephrology 2019 20:385 -
Efficacy and safety of cyclosporine a for patients with steroid-resistant nephrotic syndrome: a meta-analysis
The purpose of this study was to determine efficacy and safety of cyclosporine A (CsA) for patients with steroid-resistant nephrotic syndrome (SRNS).
Citation: BMC Nephrology 2019 20:384 -
Analysis of misdiagnosed cases of hemorrhagic fever with renal syndrome in children: two cases and literature review
Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysf...
Citation: BMC Nephrology 2019 20:383 -
The association of dialysis adequacy, body mass index, and mortality among hemodialysis patients
Although hemodialysis (HD) adequacy, single-pool Kt/Vurea (spKt/V), is inversely correlated with body size, each is known to affect patient survival in the same direction. Therefore, we sought to examine the rela...
Citation: BMC Nephrology 2019 20:382 -
Pathologic tonsillar findings similar to IgA nephropathy and the role of tonsillectomy in a patient with nephrotic syndrome
Background: The pathological findings of tonsils in IgA nephropathy include the expansion of T-cell nodules around lymphoid follicles and abnormal reticulation of the crypt epithelium in contrast to chronic to...
Citation: BMC Nephrology 2019 20:381 -
Cancer patterns and association with mortality and renal outcomes in non-dialysis dependent chronic kidney disease: a matched cohort study
Cancer in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. Cancer can be a cause or an effect of CKD. In CKD patients, a better understanding of cancer di...
Citation: BMC Nephrology 2019 20:380 -
Renal Association Clinical Practice Guideline on Haemodialysis
This guideline is written primarily for doctors and nurses working in dialysis units and related areas of medicine in the UK, and is an update of a previous version written in 2009. It aims to provide guidance...
Citation: BMC Nephrology 2019 20:379 -
Developing nephrology services in low income countries: a case of Tanzania
The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health sys...
Citation: BMC Nephrology 2019 20:378 -
Renal injury following long-term exposure to carbon disulfide: analysis of a case series
To investigate the clinicopathological characteristics of renal damage caused by long-term exposure to carbon disulfide (CS2) in nine patients.
Citation: BMC Nephrology 2019 20:377 -
A case report on lipofuscin deposition in a graft biopsy two years after kidney transplantation: an insignificant bystander or a pathogenic benefactor?
Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys. Overall, it is thought to be non-pathoge...
Citation: BMC Nephrology 2019 20:376 -
TAFRO syndrome as a cause of glomerular microangiopathy: a case report and literature review
TAFRO syndrome is a systemic inflammatory disorder that manifests as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Renal dysfunction is frequently complicated wit...
Citation: BMC Nephrology 2019 20:375 -
Treatment of lead and arsenic poisoning in anuric patients – a case report and narrative review of the literature
Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered.
Citation: BMC Nephrology 2019 20:374 -
Association of medication non-adherence with short-term allograft loss after the treatment of severe acute kidney transplant rejection
Medication non-adherence is a risk factor for acute kidney transplant rejection. The association of non-adherence with short-term allograft loss in patients who develop acute rejection and are subsequently tre...
Citation: BMC Nephrology 2019 20:373 -
A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat, administered three times weekly in patients with anemia on hemodialysis
Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD) in both dialysis and nondialysis patients. In clini...
Citation: BMC Nephrology 2019 20:372 -
Comparison between three different equations for the estimation of glomerular filtration rate in predicting mortality after coronary artery bypass
This study was undertaken to compare the accuracy of chronic kidney disease-epidemiology collaboration (eGFRCKD-EPI) to modification of diet in renal disease (eGFRMDRD) and the Cockcroft-Gault formulas of Creatin...
Citation: BMC Nephrology 2019 20:371 -
Clinical practice guideline on undernutrition in chronic kidney disease
Citation: BMC Nephrology 2019 20:370 -
Association between mineral and bone disorder in patients with acute kidney injury following cardiac surgery and adverse outcomes
Numerous studies have evaluated the prevalence and importance of mineral and bone disorders among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, little is known about d...
Citation: BMC Nephrology 2019 20:369 -
Complete post-operative resolution of “temporary” end-stage kidney disease secondary to aortic dissection without static renal artery obstruction: a case study
Acute kidney injury (AKI), which may progress to end-stage kidney disease (ESKD), is a potential complication of aortic dissection. Notably, in all reported ESKD cases secondary to aortic dissection, imaging e...
Citation: BMC Nephrology 2019 20:368 -
Early detection of acute kidney injury in the perioperative period of liver transplant with neutrophil gelatinase-associated lipocalin
Acute kidney injury (AKI) is a common complication in patients undergoing liver transplant (LT) and is associated with high morbidity and mortality. We aim to evaluate the pattern of urine and plasma neutrophi...
Citation: BMC Nephrology 2019 20:367 -
Ipilimumab-induced renal granulomatous arteritis: a case report
Immune Checkpoint Inhibitors (ICPIs) are promising new drugs in treatment of advanced tumours targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD1) or its ligand (PDL-1)...
Citation: BMC Nephrology 2019 20:366 -
The EKiTE network (epidemiology in kidney transplantation - a European validated database): an initiative epidemiological and translational European collaborative research
Kidney transplantation is considered to be the treatment of choice for people with end-stage renal disease (ESRD). However, due to the shortage of available organs and the increase in the ESRD prevalence in Eu...
Citation: BMC Nephrology 2019 20:365 -
Use of intravoxel incoherent motion imaging to monitor a rat kidney chronic allograft damage model
Chronic allograft damage (CAD) is the leading cause of long-term graft dysfunction. A noninvasive method that can diagnose CAD early and monitor its development is needed.
Citation: BMC Nephrology 2019 20:364 -
Association between the Charlson Comorbidity Index and the risk of 30-day unplanned readmission in patients receiving maintenance dialysis
Patients receiving maintenance hemodialysis (HD) and peritoneal dialysis (PD) are frequently hospitalized. Reducing unplanned 30-day hospital readmissions is a key priority for improving the quality of health ...
Citation: BMC Nephrology 2019 20:363 -
Hyperphosphatemia and risks of acute kidney injury, end-stage renal disease, and mortality in hospitalized patients
Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatem...
Citation: BMC Nephrology 2019 20:362 -
Dutch nOcturnal and hoME dialysis Study To Improve Clinical Outcomes (DOMESTICO): rationale and design
More than 6200 End Stage Renal Disease patients in the Netherlands are dependent on dialysis, either performed at home or in a dialysis centre. Visiting a dialysis centre three times a week is considered a lar...
Citation: BMC Nephrology 2019 20:361 -
Serum anti-phospholipase A2 receptor (PLA2R) antibody detected at diagnosis as a predictor for clinical remission in patients with primary membranous nephropathy: a meta-analysis
The diagnostic value of serum M-type phospholipase A2 receptor antibody (sPLA2R-ab) expression in patients with primary membranous nephropathy (PMN) has been established. However, the association between sPLA2...
Citation: BMC Nephrology 2019 20:360 -
In search of potential predictors of erythropoiesis-stimulating agents (ESAs) hyporesponsiveness: a population-based study
Evidences show that around 20% of biosimilar or originator erythropoiesis-stimulating agents (ESAs) users are hyporesponsive. Controversial post-marketing data exist on the predictors of ESA hyporesponsiveness...
Citation: BMC Nephrology 2019 20:359 -
Molecular mechanisms of hydrogen sulfide against uremic accelerated atherosclerosis through cPKCβII/Akt signal pathway
Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional pro...
Citation: BMC Nephrology 2019 20:358 -
Lab-based and diagnosis-based chronic kidney disease recognition and staging concordance
Chronic kidney disease (CKD) is often under-recognized and poorly documented via diagnoses, but the extent of under-recognition is not well understood among Medicare beneficiaries. The current study used claim...
Citation: BMC Nephrology 2019 20:357 -
Measuring the palpable pulsatility length as a physical examination test in defining the severity of inflow stenosis for hemodialysis fistulas
Pulsatility is an important property of hemodialysis arteriovenous fistulas (AVF) and can be perceived by the fingers as a gradual decrease in strength downstream from the anastomosis along the main trunk of t...
Citation: BMC Nephrology 2019 20:356 -
TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes
Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical mani...
Citation: BMC Nephrology 2019 20:355 -
Possible beneficial association between renin-angiotensin-aldosterone-system blockade usage and graft prognosis in allograft IgA nephropathy: a retrospective cohort study
Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB) usage,...
Citation: BMC Nephrology 2019 20:354 -
Case report: extreme coronary calcifications and hypomagnesemia in a patient with a 17q12 deletion involving HNF1B
17q12 deletion syndrome encompasses a broad constellation of clinical phenotypes, including renal magnesium wasting, maturity-onset diabetes of the young (MODY), renal cysts, genitourinary malformations, and n...
Citation: BMC Nephrology 2019 20:353 -
Mycophenolate mofetil and tacrolimus versus tacrolimus alone for the treatment of idiopathic membranous glomerulonephritis: a randomised controlled trial
Tacrolimus (TAC) is effective in treating membranous nephropathy (MN); however relapses are frequent after treatment cessation. We conducted a randomised controlled trial to examine whether the addition of myc...
Citation: BMC Nephrology 2019 20:352 -
Spironolactone ameliorates endothelial dysfunction through inhibition of the AGE/RAGE axis in a chronic renal failure rat model
Spironolactone can improve endothelial dysfunction in the setting of heart failure and diabetes models. However, its beneficial effect in the cardiovascular system is not clear in the setting of non-diabetic r...
Citation: BMC Nephrology 2019 20:351
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