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  1. Content type: Research article

    Health-related quality of life (HrQoL) varies among dialysis patients. However, little is known about the association of dialysis modality with HrQoL over time. We describe longitudinal patterns of HrQoL among...

    Authors: Nwamaka D. Eneanya, Dugan W. Maddux, Marta M. Reviriego-Mendoza, John W. Larkin, Len A. Usvyat, Frank M. van der Sande, Jeroen P. Kooman and Franklin W. Maddux

    Citation: BMC Nephrology 2019 20:7

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  2. Content type: Case report

    Goodpasture Syndrome (GS) is an autoimmune disease caused by the development of auto-antibodies against the Glomerular Basement Membrane (GBM). Linear deposit of immunoglobulins G on the GBM detected by immuno...

    Authors: V. Thibaud, N. Rioux-Leclercq, C. Vigneau and S. Morice

    Citation: BMC Nephrology 2019 20:6

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  3. Content type: Research article

    The optimal treatment algorithm for iron therapy and the use of erythropoiesis-stimulating agents (ESA) in anemic hemodialysis (HD) patients has not been established. Hemoglobin (Hb) target levels can be achie...

    Authors: Maciej Drozdz, André Weigert, Fatima Silva, João Frazão, Abdulkareem Alsuwaida, Mahesh Krishnan, Werner Kleophas, Szymon Brzosko, Fredrik K. Johansson and Stefan H. Jacobson

    Citation: BMC Nephrology 2019 20:5

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  4. Content type: Research article

    This cluster randomised controlled trial set out to investigate the feasibility and acceptability of the “Combined Diabetes and Renal Control Trial” (C-DIRECT) intervention, a nurse-led intervention based on m...

    Authors: K. Griva, M. Rajeswari, M. Nandakumar, E. Y. H. Khoo, V. Y. W. Lee, C. G. Chua, Z. S. Goh, Y. T. D. Choong and S. P. Newman

    Citation: BMC Nephrology 2019 20:2

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  5. Content type: Research article

    HIV-positive persons bear an excess burden of chronic kidney disease (CKD); however, conventional methods to assess kidney health are insensitive and non-specific for detecting early kidney injury. Urinary bio...

    Authors: Anthony N. Muiru, Michael G. Shlipak, Rebecca Scherzer, William R. Zhang, Simon B. Ascher, Vasantha Jotwani, Carl Grunfeld, Chirag R. Parikh, Derek Ng, Frank J. Palella Jr, Ken Ho, Seble Kassaye, Anjali Sharma, Mardge Cohen, Ruibin Wang, Qibin Qi…

    Citation: BMC Nephrology 2019 20:4

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  6. Content type: Research article

    Electronic health record (EHR) data is increasingly used to identify patients with chronic kidney disease (CKD). EHR queries used to capture CKD status, identify comorbid conditions, measure awareness by provi...

    Authors: Martin Frigaard, Anna Rubinsky, Lo Lowell, Anna Malkina, Leah Karliner, Michael Kohn and Carmen A Peralta

    Citation: BMC Nephrology 2019 20:3

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  7. Content type: Case report

    Drug-induced nephrotic syndrome (NS) can be resolved by eliminating the causative agents. However, patients with metastatic cancer have not been previously reported to achieve complete recovery from anticancer...

    Authors: So-Yeon Jeon, Na-Ri Lee and Chang-Yeol Yim

    Citation: BMC Nephrology 2019 20:1

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  8. Content type: Research article

    The worldwide prevalence of obesity is increasing. Obesity is associated with a variety of chronic diseases, including chronic kidney disease. Several studies suggested that body mass index (BMI) could be an i...

    Authors: Changwei Wu, Amanda Y. Wang, Guisen Li and Li Wang

    Citation: BMC Nephrology 2018 19:381

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  9. Content type: Research article

    Most studies on obesity surgery have measured renal function using the estimated GFR. However, due to the reduction of muscle mass, and therefore creatinine that accompanies weight loss, such measures can fals...

    Authors: Ling L. Chuah, Alexander D. Miras, Laura M. Perry, Andrew H. Frankel, David J. Towey, Zahraa Al-Mayahi, William Svensson and Carel W. le Roux

    Citation: BMC Nephrology 2018 19:383

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  10. Content type: Research article

    Congenital nephrotic syndrome (CNS) is characterised by increased proteinuria, hypoproteinemia, and edema beginning in the first 3 months of life. Recently, molecular genetic studies have identified several ge...

    Authors: Guo-min Li, Qi Cao, Qian Shen, Li Sun, Yi-hui Zhai, Hai-mei Liu, Yu An and Hong Xu

    Citation: BMC Nephrology 2018 19:382

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  11. Content type: Research article

    Estimated glomerular filtration rate (eGFR) is the clinical standard for assessing kidney function and staging chronic kidney disease. Automated reporting of eGFR using the Modification of Diet in Renal Diseas...

    Authors: Kristine E. Lynch, Ji won Chang, Michael E. Matheny, Alexander Goldfarb, Olga Efimova, Gregorio Coronado and Scott L. DuVall

    Citation: BMC Nephrology 2018 19:380

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  12. Content type: Research article

    The clinical outcome and health-related quality of life (HRQoL) of living kidney donors is mostly not detrimental, but some donors experience impairment after donation. Gender-specific effects of living kidney...

    Authors: Claudia Sommerer, Sarah Estelmann, Nicole G. Metzendorf, Maren Leuschner and Martin Zeier

    Citation: BMC Nephrology 2018 19:377

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  13. Content type: Research article

    Caffeine has been proposed, based on in vitro cultured cell studies, to accelerate progression of autosomal dominant polycystic kidney disease (ADPKD) by increasing kidney size. Since ADPKD patients are advise...

    Authors: Katelyn A. McKenzie, Mirelle El Ters, Vicente E. Torres, Peter C. Harris, Arlene B. Chapman, Michal Mrug, Frederic F. Rahbari-Oskoui, Kyongtae Ty Bae, Douglas P. Landsittel, William M. Bennett, Alan S. L. Yu and Jonathan D. Mahnken

    Citation: BMC Nephrology 2018 19:378

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  14. Content type: Research article

    The prevalence of cognitive disorders in hemodialysis patients is twice as high as the general population, while these disorders often are undiagnosed. Timely prevention and treatment can improve their persona...

    Authors: Afshin Samaei, Monir Nobahar, Zaynab Hydarinia-Naieni, Abbas Ali Ebrahimian, Mohammad Reza Tammadon, Raheb Ghorbani and Abbas Ali Vafaei

    Citation: BMC Nephrology 2018 19:379

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  15. Content type: Research article

    To assess the time to first on-study vascular thromboembolic events (VTEs) of clopidogrel (CL) or beraprost sodium (BPS) in Chinese population with end-stage renal disease (ESRD) treated with arteriovenous fis...

    Authors: Yu Zhou, Ling Du, Bo Tu, Qiquan Lai, Xiaonan Du, Bo Xu, Fan Zhang, Mingdong Zhao, Ziming Wan and Jiajie Lai

    Citation: BMC Nephrology 2018 19:376

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  16. Content type: Correction

    Following publication of the original article [1], the authors reported an error in the presentation of Table 3 and Table 4.

    Authors: Jutta Dierkes, Helene Dahl, Natasha Lervaag Welland, Kristina Sandnes, Kristin Sæle, Ingegjerd Sekse and Hans-Peter Marti

    Citation: BMC Nephrology 2018 19:375

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    The original article was published in BMC Nephrology 2018 19:259

  17. Content type: Research article

    Recent studies have shown associations between contrast-induced acute kidney injury (CI-AKI) and increased risk of adverse clinical outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous co...

    Authors: Yi Yang, Kaisha C. George, Ran Luo, Yichun Cheng, Weifeng Shang, Shuwang Ge and Gang Xu

    Citation: BMC Nephrology 2018 19:374

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  18. Content type: Research article

    The impact of contrast-induced acute kidney injury (CI-AKI) on patients with chronic renal disease is well-known. Remote ischemic preconditioning (RIPC) is a non-invasive method that can reduce the risk of CI-...

    Authors: Ali Ghaemian, Jamshid Yazdani, Soheil Azizi, Ali A. Farsavian, Maryam Nabati, Alireza Malekrah, Mozhdeh Dabirian, Fatemeh Espahbodi, Bahareh Mirjani, Hossein Mohsenipouya and Javad Heshmatian

    Citation: BMC Nephrology 2018 19:373

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  19. Content type: Case report

    Lupus nephritis (LN) is one of the most common manifestations of systemic lupus erythematosus (SLE) and is often the most serious organ complication and the cause of premature death of such a patient. Most of ...

    Authors: Marceli Lukaszewski, Kinga Kosiorowska, Dorota Kaminska, Marta Obremska, Oktawia Mazanowska and Magdalena Krajewska

    Citation: BMC Nephrology 2018 19:372

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  20. Content type: Research article

    Somatostatin (SST) inhibits intracellular cyclic adenosine monophosphate (cAMP) production and thus may modify cyst formation in autosomal dominant polycystic kidney disease (ADPKD). We investigated whether en...

    Authors: A. Lianne Messchendorp, Edwin M. Spithoven, Niek F. Casteleijn, Wendy A. Dam, Jacob van den Born, Wouter F. Tonnis, Carlo A. J. M. Gaillard and Esther Meijer

    Citation: BMC Nephrology 2018 19:368

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  21. Content type: Research article

    This is the first qualitative study to explore patient decision-making regarding end-stage kidney disease (ESKD) treatment in sub-Saharan Africa. The study addresses an important gap in the literature concerni...

    Authors: Edward Appiah Boateng, Linda East and Catrin Evans

    Citation: BMC Nephrology 2018 19:371

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  22. Content type: Research article

    The introduction of a continuous renal replacement therapy (CRRT) device into the extracorporeal membrane oxygenation (ECMO) circuit is widely used. However, excessive pressure transmitted to the CRRT device i...

    Authors: Soo Jin Na, Hee Jung Choi, Chi Ryang Chung, Yang Hyun Cho, Hye Ryoun Jang, Gee Young Suh and Kyeongman Jeon

    Citation: BMC Nephrology 2018 19:369

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  23. Content type: Case report

    Uremic encephalopathy (UE), a toxic metabolic encephalopathy, is an uncommon complication resulting from endogenous uremic toxins in patients with severe renal failure. UE syndrome can range from mild inattent...

    Authors: Wen-Yu Gong, Shan-Shan Li, Zong-Chao Yu, Hong-Wei Wu, Liang-Hong Yin, Li-Fan Mei and Fan-Na Liu

    Citation: BMC Nephrology 2018 19:370

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  24. Content type: Research article

    Urinary mitochondrial DNA (mtDNA) fragment level has been proposed as a biomarker of chronic kidney disease (CKD). In this study, we determine the relation between urinary mtDNA level and rate of renal functio...

    Authors: Zhongping WEI, Bonnie Ching-Ha KWAN, Kai Ming CHOW, Phyllis Mei-Shan CHENG, Cathy Choi-Wan LUK, Ka-Bik LAI, Philip Kam-Tao LI and Cheuk Chun SZETO

    Citation: BMC Nephrology 2018 19:367

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  25. Content type: Research article

    Estimation of GFR (eGFR) using formulae based on serum creatinine concentrations are commonly used to assess kidney function. Physical exercise can increase creatinine turnover and lean mass; therefore, this m...

    Authors: Kassia S. Beetham, Erin J. Howden, Nicole M. Isbel and Jeff S. Coombes

    Citation: BMC Nephrology 2018 19:366

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  26. Content type: Research article

    Evidence regarding the effect of psychosocial factors on hospital readmission in the setting of hemodialysis is limited. We examined whether social worker-assessed factors were associated with 30-day readmissi...

    Authors: Olufunmilola Adisa, Bernard G. Jaar, Tahsin Masud, Abyalew Sahlie, Catherine Obadina, Joshua Ang, Janice P. Lea and Laura C. Plantinga

    Citation: BMC Nephrology 2018 19:360

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  27. Content type: Research article

    Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as...

    Authors: Andrzej Jaroszyński, Anna Jaroszyńska, Tomasz Zaborowski, Anna Drelich-Zbroja, Tomasz Zapolski and Wojciech Dąbrowski

    Citation: BMC Nephrology 2018 19:359

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  28. Content type: Case report

    Although the renal toxicity of Deferasirox, an oral iron chelator, has been reported to be mild, there have been reports of acute interstitial nephritis or Fanconi syndrome due to this agent. Thin basement mem...

    Authors: Keiko Oda, Kan Katayama, Akiko Tanoue, Tomohiro Murata, Yumi Hirota, Shoko Mizoguchi, Yosuke Hirabayashi, Takayasu Ito, Eiji Ishikawa, Kaoru Dohi and Masaaki Ito

    Citation: BMC Nephrology 2018 19:363

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  29. Content type: Case report

    Distal renal tubular acidosis (dRTA) is a heterogeneous disorder characterized by normal anion gap metabolic acidosis. Autosomal recessive dRTA is usually caused by mutations occurring in ATP6V1B1 and ATP6V0A4...

    Authors: Xiangzhong Zhao, Jingru Lu, Yanxia Gao, Xiaoling Wang, Yanhua Lang and Leping Shao

    Citation: BMC Nephrology 2018 19:364

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  30. Content type: Case report

    Bordetella pertussis infection is a known trigger of atypical hemolytic uremic syndrome (HUS). For patients suspected of having atypical HUS, prompt plasma exchange/infusion (PE/PI) or eculizumab (ECZ) treatment ...

    Authors: Ken Saida, Masao Ogura, Yuji Kano, Shingo Ishimori, Takahisa Yoshikawa, Hiroko Nagata, Mai Sato, Koichi Kamei and Kenji Ishikura

    Citation: BMC Nephrology 2018 19:365

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  31. Content type: Research article

    Therapeutic plasma exchange (TPE) is an important therapy for recurrent focal segmental glomerulosclerosis (rFSGS) post kidney transplant. suPAR has been causally implicated in rFSGS, and shown to be a unique ...

    Authors: Nada Alachkar, Jing Li, Dany Matar, Vikas Vujjini, Sami Alasfar, Melissa Tracy, Jochen Reiser and Changli Wei

    Citation: BMC Nephrology 2018 19:361

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  32. Content type: Research article

    IgA nephropathy (IgAN) is one of the most common forms of idiopathic glomerular diseases and might lead to end-stage kidney disease. Accurate and non-invasive biomarkers for early diagnosis are required for ea...

    Authors: Zhengguang Guo, Zhao Wang, Chen Lu, Shufen Yang, Haidan Sun, Reziw, Yu Guo, Wei Sun and Hua Yue

    Citation: BMC Nephrology 2018 19:358

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  33. Content type: Research article

    The hepatic circulation is involved in adaptive systemic responses to circulatory stress. However, it is vulnerable to both chronic hypervolemia and cardiac dysfunction. The influence of hemodialysis (HD) and ...

    Authors: Claire J. Grant, Trevor P. Wade, Charles A. McKenzie, Guido Filler, Christopher W. McIntyre and Shih-Han S. Huang

    Citation: BMC Nephrology 2018 19:356

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  34. Content type: Case report

    Renal thrombotic microangiopathy (TMA) is occasionally seen in biopsies with pauci-immune necrotizing crescentic glomerulonephritis (PCGN). Recent study indicated that the complement activation is more promine...

    Authors: Jianling Tao, Jonathan Lieberman, Richard A. Lafayette and Neeraja Kambham

    Citation: BMC Nephrology 2018 19:355

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  35. Content type: Research article

    Serum anti-phospholipase A2 receptor (PLA2R) antibody was correlated with disease activity of membranous nephropathy(MN). The predictive value of antibody titer changes on immunosuppressive response remains un...

    Authors: Chao Li, Hang Li, Yu-bing Wen, Xue-mei Li and Xue-wang Li

    Citation: BMC Nephrology 2018 19:354

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  36. Content type: Research article

    Immunosuppressive treatment will predispose an idiopathic membranous nephropathy (iMN) patient to opportunistic infections. Disease severity is one of the main concerns for making the treatment decision. Urina...

    Authors: Ziyong Tang, Yue Wang, Liyuan Tao, Yanhong Guo, Yimu Zheng and Danxia Zheng

    Citation: BMC Nephrology 2018 19:357

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    The Correction to this article has been published in BMC Nephrology 2019 20:50

  37. Content type: Research article

    Contrast enhanced ultrasonography (CEUS) assessment of kidney allografts mainly focuses on graft rejection. However, studies on delayed graft function (DGF) without acute rejection are still lacking. The aim o...

    Authors: Nordeval Cavalcante Araújo and José Hermógenes Rocco Suassuna

    Citation: BMC Nephrology 2018 19:351

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  38. Content type: Research article

    The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serolog...

    Authors: Yun Soo Hong, Seungho Ryu, Yoosoo Chang, Miguel Caínzos-Achirica, Min-Jung Kwon, Di Zhao, Tariq Shafi, Mariana Lazo, Roberto Pastor-Barriuso, Hocheol Shin, Juhee Cho and Eliseo Guallar

    Citation: BMC Nephrology 2018 19:353

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  39. Content type: Case report

    Baclofen is a centrally acting GABAB receptor agonist and it is used widely for the treatment of spasticity, persistent hiccups and multiple sclerosis. The renal system is the main route of excretion, thus people...

    Authors: Emad Khazneh, Alaa Shamlawi, Kamel Jebrin, Zakaria Hamdan and Osama Sawalmeh

    Citation: BMC Nephrology 2018 19:352

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  40. Content type: Study protocol

    Nephrolithiasis is a global healthcare problem with a current lifetime risk of 18.8% in men and 9.4% in women. Given the high cost of medical treatments and surgical interventions as well as the morbidity rela...

    Authors: Nasser A. Dhayat, Nicolas Faller, Olivier Bonny, Nilufar Mohebbi, Alexander Ritter, Lisa Pellegrini, Giulia Bedino, Carlo Schönholzer, Reto M. Venzin, Carina Hüsler, Irene Koneth, Rosaria Del Giorno, Luca Gabutti, Patrizia Amico, Michael Mayr, Urs Odermatt…

    Citation: BMC Nephrology 2018 19:349

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  41. Content type: Case report

    Maternally inherited diabetes and deafness (MIDD), a mitochondrial genetic disorder, typically affects the kidneys and results in end-stage renal disease. Early diagnosis of MIDD is challenging when renal mani...

    Authors: Keiji Sugai, Hiroyuki Ueda, Keita Morimoto, Mai Tanaka, Daisuke Takahashi, Akio Nakashima, Junichiro Kato, Hiroshi Takahashi, Yutaka Yamaguchi, Tetsuya Kawamura, Kazushige Hanaoka, Yoichi Miyazaki and Takashi Yokoo

    Citation: BMC Nephrology 2018 19:350

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  42. Content type: Case report

    Post-transplant diabetes mellitus (PTDM) is an emerging problem in kidney transplantation, representing an important risk factor for kidney function loss. Diabetic nephropathy (DN) occurrence in transplanted k...

    Authors: Marilena Gregorini, Vincenzo Sepe, Francesca Eleonora Pattonieri, Anna Allesina and Teresa Rampino

    Citation: BMC Nephrology 2018 19:348

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  43. Content type: Research article

    The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in c...

    Authors: Julius E. Kieswich, Jianmin Chen, Samira Alliouachene, Paul W. Caton, Kieran McCafferty, Christoph Thiemermann and Muhammad M. Yaqoob

    Citation: BMC Nephrology 2018 19:346

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  44. Content type: Research article

    Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the ...

    Authors: Antonio Mirijello, Francesca Viazzi, Paola Fioretto, Carlo Giorda, Antonio Ceriello, Giuspina T. Russo, Pietro Guida, Roberto Pontremoli and Salvatore De Cosmo

    Citation: BMC Nephrology 2018 19:347

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  45. Content type: Research article

    Chronic Kidney Disease (CKD), the worldwide Public Health problem, is also one of the rising non-communicable diseases in low and middle-income countries. Its early detection and treatment using readily availa...

    Authors: Tamiru Adugna, Hailu Merga and Esayas Kebede Gudina

    Citation: BMC Nephrology 2018 19:345

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  46. Content type: Research article

    Acute kidney injury (AKI) is an underestimated, yet important, risk factor for the development of chronic kidney disease (CKD). Persistence of inflammation after a renal ischemic injury has been observed, both...

    Authors: Lies Moonen, Hilde Geryl, Patrick C. D’Haese and Benjamin A. Vervaet

    Citation: BMC Nephrology 2018 19:343

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  47. Content type: Research article

    Like most of the sub-Saharan countries, Tanzania faces significant increase in the number of patients diagnosed with an end-stage renal disease (ESRD) among which only a few manage to receive chronic haemodial...

    Authors: Godwin Pancras, Judith Shayo and Amani Anaeli

    Citation: BMC Nephrology 2018 19:342

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  48. Content type: Case report

    Peritoneal dialysis (PD)-associated infection caused by Mycobacterium spp. is rare. Mycobacterium abscessus is one of the most resistant acid-fast bacteria, and treatment is also the most difficult and refractory...

    Authors: Ryuichi Yoshimura, Miharu Kawanishi, Shungo Fujii, Aska Yamauchi, Kentaro Takase, Kaori Yoshikane, Masahiro Egawa, Hiroaki Shiina and Takafumi Ito

    Citation: BMC Nephrology 2018 19:341

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