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  1. Proteinuria, a marker of kidney injury, may be related to skeletal muscle loss. Whether the severity of proteinuria is associated with physical performance is unclear.

    Authors: Chia-Hao Fan, Ssu-Chin Lin, Kun-Zhe Tsai, Tsung-Jui Wu, Yen-Po Lin, Yu-Kai Lin, Shao-Chi Lu, Chih-Lu Han and Gen-Min Lin

    Citation: BMC Nephrology 2020 21:287

    Content type: Research article

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  2. While histopathologic changes correlate with functional impairment in cross-sectional studies of diabetic nephropathy (DN), whether these findings predict future rate of kidney function loss remains uncertain....

    Authors: Paraish S. Misra, Stephen G. Szeto, Adriana Krizova, Richard E. Gilbert and Darren A. Yuen

    Citation: BMC Nephrology 2020 21:285

    Content type: Research article

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  3. We previously identified two acute kidney injury (AKI) sub-phenotypes (AKI-SP1 and AKI-SP2) with different risk of poor clinical outcomes and response to vasopressor therapy. Plasma biomarkers of endothelial d...

    Authors: Pavan K. Bhatraju, Max Cohen, Ryan J. Nagao, Eric D. Morrell, Susanna Kosamo, Xin-Ya Chai, Robin Nance, Victoria Dmyterko, Joseph Delaney, Jason D. Christie, Kathleen D. Liu, Carmen Mikacenic, Sina A. Gharib, W. Conrad Liles, Ying Zheng, David C. Christiani…

    Citation: BMC Nephrology 2020 21:284

    Content type: Research article

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  4. The prognosis for renal function in anti-GBM glomerulonephritis (anti-GBM GN) is extremely poor, and when renal impairment progresses severely, it is difficult to expect improvement. In addition, it is also kn...

    Authors: Yuko Shibata, Kazuhito Fukuoka, Riyo Yokota, Heryon Lee, Hikaru Sayo, Noriko Ikegaya, Kiyotaka Mori, Jin Yamamoto, Aya Isomura, Kiyotaka Nagahama, Hiroaki Shimoyamada, Takahisa Kawakami, Yoshinori Komagata and Shinya Kaname

    Citation: BMC Nephrology 2020 21:283

    Content type: Case report

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  5. Renal hypouricemia (RHUC) is a genetic disorder caused by mutations in the SLC22A12 gene, which encodes the major uric acid (UA) transporter, URAT1. The clinical course of related, living donor-derived RHUC in pa...

    Authors: Kiyokazu Tsuji, Mineaki Kitamura, Kumiko Muta, Yasushi Mochizuki, Takayasu Mori, Eisei Sohara, Shinichi Uchida, Hideki Sakai, Hiroshi Mukae and Tomoya Nishino

    Citation: BMC Nephrology 2020 21:282

    Content type: Case report

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  6. Increased oxidative stress in end-stage renal disease is regarded as one of the important mechanisms in the atherosclerosis and muscle wasting. However, studies examining the clinical significance of oxidative...

    Authors: Young Rim Song, Jwa-Kyung Kim, Hyung-Seok Lee, Sung Gyun Kim and Eun-Kyoung Choi

    Citation: BMC Nephrology 2020 21:281

    Content type: Research article

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  7. Serum creatinine (Cr) and cystatin C (CysC) can both be used to estimate glomerular filtration rate (eGFRCr and eGFRCysC). However, certain conditions may cause discrepancies between eGFR trends from Cr and CysC,...

    Authors: Eunjeong Kang, Seung Seok Han, Jayoun Kim, Sue Kyung Park, Wookyung Chung, Yun Kyu Oh, Dong-Wan Chae, Yong-Soo Kim, Curie Ahn and Kook-Hwan Oh

    Citation: BMC Nephrology 2020 21:280

    Content type: Research article

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  8. Vascular calcification (VC) is well described in large- and medium-sized vessels in patients with chronic kidney disease (CKD), especially in those with end-stage kidney disease (ESKD) on dialysis. Medial calc...

    Authors: Irene Ruderman, Tim D. Hewitson, Edward R. Smith, Stephen G. Holt, Belinda Wigg and Nigel D. Toussaint

    Citation: BMC Nephrology 2020 21:279

    Content type: Research article

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  9. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Kyle Hayes, Elizabeth Warner, Chris Bollinger, Dale Wright and Richard M. Fitch

    Citation: BMC Nephrology 2020 21:278

    Content type: Correction

    Published on:

    The original article was published in BMC Nephrology 2020 21:226

  10. Focal segmental glomerulosclerosis (FSGS) causes renal fibrosis and may lead to kidney failure. FSGS and its common complication, proteinuria, are challenging to treat. Corticosteroids are ineffective in many ...

    Authors: Kyle Hayes, Elizabeth Warner, Chris Bollinger, Dale Wright and Richard M. Fitch

    Citation: BMC Nephrology 2020 21:226

    Content type: Research article

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    The Correction to this article has been published in BMC Nephrology 2020 21:278

  11. Tetralogy of Fallot is the most common cyanotic congenital heart disease. Patients with the condition have a high risk of developing chronic kidney disease. Treatment of kidney disease in patients with complex...

    Authors: Tetsuya Abe, Togo Aoyama, Keiko Sano, Ryoma Miyasaka, Takuya Yamazaki, Yukari Honma, Hiroshi Tominaga, Maoko Ida, Aya Arao, Mayuko Sakakibara, Keiko Hashimoto, Haruka Takahashi, Takeshi Sakai, Shokichi Naito, Toshimi Koitabashi, Takashi Sano…

    Citation: BMC Nephrology 2020 21:277

    Content type: Case report

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  12. Sodium-glucose co-transporter-2 (SGLT-2) inhibitors are a relatively novel class of oral medications for the treatment of Type 2 DM with a generally acceptable safety profile. However, these agents have been a...

    Authors: Erasmia Sampani, Pantelis Sarafidis, Chrysostomos Dimitriadis, Efstratios Kasimatis, Dimitra Daikidou, Konstantinos Bantis, Alexios Papanikolaou and Aikaterini Papagianni

    Citation: BMC Nephrology 2020 21:276

    Content type: Case report

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  13. Erythropoietin-stimulating agents (ESAs) are used to treat anemia in patients with chronic kidney disease, enabling maintenance of stable hemoglobin levels and eliminating the need for multiple transfusions. E...

    Authors: Yasuki Shingu, Tomohiro Nakata, Shinji Sawai, Hisaya Tanaka, Osamu Asai, Keiichi Tamagaki and Kimihiko Nakatani

    Citation: BMC Nephrology 2020 21:275

    Content type: Case report

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  14. Mitochondrial dysfunction contributes to the pathogenesis of diabetic nephropathy (DN). Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role in the transpo...

    Authors: Huanhuan Zhu, Huiting Wan, Lin Wu, Qing Li, Simeng Liu, Suyan Duan, Zhimin Huang, Chengning Zhang, Bo Zhang, Changying Xing and Yanggang Yuan

    Citation: BMC Nephrology 2020 21:274

    Content type: Research article

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  15. Renal infarction (RI) is a rare disease with poor prognosis. Appropriate secondary prevention treatment is essential and requires an exhaustive etiological assessment. We aimed to determine whether invasive en...

    Authors: Fabrice Ivanes, Jean Dewaele, Caroline Touboul, Philippe Gatault, Bénédicte Sautenet, Christelle Barbet, Matthias Büchler, Laurent Quilliet, Denis Angoulvant and Jean-Michel Halimi

    Citation: BMC Nephrology 2020 21:273

    Content type: Research article

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  17. Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, t...

    Authors: Fangfang Xiang, Rongyi Chen, Xuesen Cao, Bo Shen, Xiaohong Chen, Xiaoqiang Ding and Jianzhou Zou

    Citation: BMC Nephrology 2020 21:271

    Content type: Research article

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  18. Chronic kidney disease (CKD) is characterized by inflammation, injury and fibrosis. Dysregulated innate immune responses mediated by macrophages play critical roles in progressive renal injury. The differentia...

    Authors: Hewang Lee, Michael B. Fessler, Peng Qu, Jurgen Heymann and Jeffrey B. Kopp

    Citation: BMC Nephrology 2020 21:270

    Content type: Review

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  19. Medical investigation is a favorite application of Ockham’s razor, in virtue of which when presented with competing hypotheses, the solution with the fewest assumptions should be privileged. Hemolytic uremic s...

    Authors: Chloe Schwarz, Alice Brehon, Cyril Mousseaux, Yosu Luque, Patricia Senet, Patricia Mariani, Inna Mohamadou, Lara Zafrani, Véronique Frémeaux-Bacchi, Eric Rondeau, David Buob and Cédric Rafat

    Citation: BMC Nephrology 2020 21:269

    Content type: Case report

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  20. An appropriate diet is an important determinant of kidney health. However, the association between vegetarian diets and renal function is unclear. We aimed to study the association between vegetarian diets and...

    Authors: Kaijie Xu, Xueying Cui, Bian Wang, Qingya Tang, Jianfang Cai and Xiuhua Shen

    Citation: BMC Nephrology 2020 21:268

    Content type: Research article

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  21. Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis...

    Authors: Bing-Biao Lin, Ming-En Lin, Rong-Hua Huang, Ying-Kai Hong, Bing-Liang Lin and Xue-Jun He

    Citation: BMC Nephrology 2020 21:267

    Content type: Research article

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  22. Setting the dry weight and maintaining fluid balance is still a difficult challenge in dialysis patients. Overhydration is common and associated with increased cardiac morbidity and mortality. Pulmonary hypert...

    Authors: Anne Rudbeck Juhl, Jesper Juul Larsen, Kasper Rossing and Lisbet Brandi

    Citation: BMC Nephrology 2020 21:266

    Content type: Case report

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  23. C3 glomerulonephritis is a recently described entity with heterogeneous histopathological features. This study was conducted to assess the effect of reclassification of C3 glomerulopathies on renal outcomes, m...

    Authors: P. Puri, G. D. Walters, M. N. Fadia, M. Konia, K. A. Gibson and S. H. Jiang

    Citation: BMC Nephrology 2020 21:265

    Content type: Research article

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  24. Haemodialysis (HD) patients are burdened by frequent fluid shifts which amplify their comorbidities. Bioimpedance (bioZ) is a promising technique to monitor changes in fluid status. The aim of this study is to...

    Authors: Melanie K. Schoutteten, Julie Vranken, Seulki Lee, Christophe J. P. Smeets, Hélène De Cannière, Chris Van Hoof, Jacques Peeters, Willemijn Groenendaal and Pieter M. Vandervoort

    Citation: BMC Nephrology 2020 21:264

    Content type: Technical advance

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  25. The currently available data with respect to the association between vitamin D receptor (VDR) gene polymorphism and risk to urolithiasis are inconclusive and inconsistent. Hence, an exhaustive meta-analysis can s...

    Authors: Danyal Imani, Bahman Razi, Arezou Khosrojerdi, Kaivan Lorian, Morteza Motallebnezhad, Ramazan Rezaei and Saeed Aslani

    Citation: BMC Nephrology 2020 21:263

    Content type: Research article

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  26. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ylenia Ingrasciotta, Viviana Lacava, Ilaria Marcianò, Francesco Giorgianni, Giovanni Tripepi, Graziella D’. Arrigo, Alessandro Chinellato, Daniele Ugo Tari, Domenico Santoro and Gianluca Trifirò

    Citation: BMC Nephrology 2020 21:262

    Content type: Correction

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    The original article was published in BMC Nephrology 2019 20:359

  27. Patients receiving chronic hemodialysis treatments are at a higher risk of fracture compared to the general population. While the use of heparin during dialysis is crucial to avoid thrombosis of the extracorpo...

    Authors: Hind Harrak, Emilie René, Noor Alsalemi, Naoual Elftouh and Jean-Philippe Lafrance

    Citation: BMC Nephrology 2020 21:261

    Content type: Research article

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  28. The seroprevalence of human Parvovirus B19 (PVB19) is 70–85% in adults worldwide. PVB19 is the etiologic agent of the fifth disease, is a cause of aplastic anemia, and can be associated with kidney injury. We ...

    Authors: Maëlis Kauffmann, Mickaël Bobot, Laurent Daniel, Julia Torrents, Yannick Knefati, Olivier Moranne, Stéphane Burtey, Christine Zandotti and Noémie Jourde-Chiche

    Citation: BMC Nephrology 2020 21:260

    Content type: Research article

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  29. The impact of anemia treatment with erythropoietin stimulating agents (ESA) on health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients is controversial, particularly regarding optimal h...

    Authors: Murilo Guedes, Camila R. Guetter, Lucas H. O. Erbano, Andre G. Palone, Jarcy Zee, Bruce M. Robinson, Ronald Pisoni, Thyago Proença de Moraes, Roberto Pecoits-Filho and Cristina P. Baena

    Citation: BMC Nephrology 2020 21:259

    Content type: Research article

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  30. Lupus nephritis is associated with increased risk of end-stage renal disease (ESRD) and all-cause mortality. We evaluated the clinical features and outcomes of patients with early and delayed lupus nephritis.

    Authors: Sung Soo Ahn, Juyoung Yoo, Seung Min Jung, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee

    Citation: BMC Nephrology 2020 21:258

    Content type: Research article

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  31. Secondary hyperparathyroidism (SHPT) is a common high-risk factor for mortality in end-stage renal disease, and parathyromatosis and supernumerary parathyroid glands are very rare causes of persistent SHPT. Pr...

    Authors: Jun Yang, Jun Zhang, Ning-hu Liu, Hao Liu and Meng-jie Dong

    Citation: BMC Nephrology 2020 21:257

    Content type: Case report

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  32. Renal loss of potassium (K+) and magnesium (Mg2+) in salt losing tubulopathies (SLT) leads to significantly reduced Quality of Life (QoL) and higher risks of cardiac arrhythmia. The normalization of K+ is current...

    Authors: Michael Eder, Elisabeth Darmann, Maria C. Haller, Marija Bojic, Markus Peck-Radosavljevic, Rainer Huditz, Gregor Bond, Andreas Vychytil, Roman Reindl-Schwaighofer and Željko Kikić

    Citation: BMC Nephrology 2020 21:256

    Content type: Research article

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  33. In recent years, the diagnostic utility of urinary protein levels has been demonstrated for the early detection and progression of kidney disease. This study aimed to evaluate the associations of the non-album...

    Authors: Khalid Siddiqui, Salini Scaria Joy, Shaik Sarfaraz Nawaz, Dhekra Alnaqeb, Muhammad Mujammami and Khalid Al-Rubeaan

    Citation: BMC Nephrology 2020 21:255

    Content type: Research article

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  34. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Currie Moore, Lesley-Anne Carter, Sandip Mitra, Suzanne Skevington and Alison Wearden

    Citation: BMC Nephrology 2020 21:254

    Content type: Correction

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    The original article was published in BMC Nephrology 2020 21:185

  35. Angiotensin II type 1 receptors (AT1Rs) are expressed on podocytes, endothelial and other cells, and play an essential role in the maintenance of podocyte function and vascular homeostasis. The presence of AT1...

    Authors: Mohammad Abuzeineh, Amtul Aala, Sami Alasfar and Nada Alachkar

    Citation: BMC Nephrology 2020 21:253

    Content type: Research article

    Published on:

  36. According to the “lipid nephrotoxicity hypothesis”, there is now significant research being conducted in this area. By studying the role of hyperlipidemia in chronic kidney disease in the general Zhejiang popu...

    Authors: Xudong Liang, Meiyu Ye, Mei Tao, Danna Zheng, Ruyi Cai, Yifan Zhu, Juan Jin and Qiang He

    Citation: BMC Nephrology 2020 21:252

    Content type: Research article

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  37. The occurrences of hyperuricemia and acute kidney injury after antithymocyte globulin treatment are unusual in kidney transplant recipients. Here, we report a unique case of acute kidney injury with extreme hy...

    Authors: Yohan Park, Byung Ha Chung, Cheol Whee Park, Yong-Soo Kim and Chul Woo Yang

    Citation: BMC Nephrology 2020 21:251

    Content type: Case report

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  38. Access to kidney transplantation by uremic children is very limited due to the lack of donors in many countries. We sought to explore small pediatric kidney donors as a strategy to provide transplant opportuni...

    Authors: Xiaojun Su, Wenjun Shang, Longshan Liu, Jun Li, Qian Fu, Yonghua Feng, Huanxi Zhang, Ronghai Deng, Chenglin Wu, Zhigang Wang, Xinlu Pang, Björn Nashan, Guiwen Feng and Changxi Wang

    Citation: BMC Nephrology 2020 21:250

    Content type: Research article

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  39. Renal replacement therapy (RRT) places a burden on patients, and geographical relocation for easier access to healthcare facilities is a necessity for some. Incidence and factors associated with relocation has...

    Authors: Hicham I Cheikh Hassan, Jenny HC Chen and Karumathil Murali

    Citation: BMC Nephrology 2020 21:249

    Content type: Research article

    Published on:

  41. The 2016 Oxford Classification’s MEST-C scoring system predicts outcomes in adults with IgA nephropathy (IgAN), but it lacks tremendous cohort validation in children with IgAN in China. We sought to verify whe...

    Authors: Heyan Wu, Zhengkun Xia, Chunlin Gao, Pei Zhang, Xiao Yang, Ren Wang, Meiqiu Wang and Yingchao Peng

    Citation: BMC Nephrology 2020 21:247

    Content type: Research article

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  43. Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney an...

    Authors: Rachael D. Wright, Fariba Bannerman, Michael W. Beresford and Louise Oni

    Citation: BMC Nephrology 2020 21:245

    Content type: Research article

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  44. Several studies have reported that lower body mass index (BMI) is associated with high mortality in patients with chronic kidney disease (CKD). Rate of infection-related death in CKD patients is increasing. Ho...

    Authors: Tae Yamamoto, Masaaki Nakayama, Mariko Miyazaki, Hiroshi Sato, Masato Matsushima, Toshinobu Sato and Sadayoshi Ito

    Citation: BMC Nephrology 2020 21:244

    Content type: Research article

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  45. To explore the potential value of three-dimensional ultrasonography (3DUS) and contrast-enhanced ultrasound (CEUS) in the diagnosis of diabetic nephropathy (DN) in Chinese diabetic patients with kidney injury.

    Authors: Nan Li, Yi-ru Wang, Xiao-qi Tian, Lin Lin, Shu-yuan Liang, Qiu-yang Li, Xiang Fei, Jie Tang and Yu-kun Luo

    Citation: BMC Nephrology 2020 21:243

    Content type: Research article

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  46. Diabetic kidney disease (DKD) remains one of the leading causes of premature death in diabetes. DKD is classified on albuminuria and reduced kidney function (estimated glomerular filtration rate (eGFR)) but th...

    Authors: Kim M. Gooding, Chrysta Lienczewski, Massimo Papale, Niina Koivuviita, Marlena Maziarz, Anna-Maria Dutius Andersson, Kanishka Sharma, Paola Pontrelli, Alberto Garcia Hernandez, Julie Bailey, Kay Tobin, Virva Saunavaara, Anna Zetterqvist, David Shelley, Irvin Teh, Claire Ball…

    Citation: BMC Nephrology 2020 21:242

    Content type: Study protocol

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  47. Constrictive pericarditis is easily overlooked and can lead to severe problems in hemodynamics and end-organ perfusion, in our patient leading to 98 days of anuria after living kidney transplantation. This was...

    Authors: Caroline Wacker, Michael Weyand, Mario Schiffer and Mirian Opgenoorth

    Citation: BMC Nephrology 2020 21:241

    Content type: Case report

    Published on:

  48. Preeclampsia (PE) refers to the development of hypertension and new-onset proteinuria or progressive organ damage (especially kidney) in a previously normotensive pregnant women after 20 weeks of gestation. Th...

    Authors: Tomo Suzuki, Daisuke Ichikawa, Mayumi Nakata, Shiika Watanabe, Wei Han, Kaori Kohatsu, Sayuri Shirai, Naohiko Imai, Junki Koike and Yugo Shibagaki

    Citation: BMC Nephrology 2020 21:240

    Content type: Case report

    Published on:

  49. Dialysis patients have a high pill burden, increasing their care complexity. A previous study in our institution’s dialysis unit found notable discrepancies between medication prescriptions, purchases and pati...

    Authors: Lee Gilad, Yosef S. Haviv, Inbal Cohen-Glickman, David Chinitz and Matan J. Cohen

    Citation: BMC Nephrology 2020 21:239

    Content type: Research article

    Published on:

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