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  1. Content type: Case report

    Microangiopathic hemolytic anemias and thrombocytopenias in pregnant or postpartum women constitute an interdisciplinary diagnostic and therapeutic challenge in the evaluation of thrombotic microangiopathies (...

    Authors: Katharina Artinger, Gerald Hackl, Gernot Schilcher, Florian Eisner, Marion J. Pollheimer, Christoph Mache, Eva-Christine Weiss, Kathrin Eller and Philipp Eller

    Citation: BMC Nephrology 2019 20:91

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  2. Content type: Research article

    Darbepoetin alfa (DA-α) is a long-acting erythropoiesis-stimulating glycoprotein which has half-life three-fold longer than that of Erythropoietin alfa (EPO). The objective of this study was to compare the eff...

    Authors: Shubhadeep D. Sinha, Vamsi Krishna Bandi, Bala Reddy Bheemareddy, Pankaj Thakur, Sreenivasa Chary, Kalpana Mehta, Vikranth Reddy Pinnamareddy, Rajendra Pandey, Subhramanyam Sreepada and Santosh Durugkar

    Citation: BMC Nephrology 2019 20:90

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  3. Content type: Research article

    Acute kidney injury (AKI) in critically ill children is associated with increased mortality and morbidity. In this study we evaluated the effect of AKI severity on the incidence of short-term mortality and mor...

    Authors: Osama Y. Safder, Khalid A. Alhasan, Mohamed A. Shalaby, Norah Khathlan, Suleman A. Al Rezgan, Amr S. Albanna and Jameela A. Kari

    Citation: BMC Nephrology 2019 20:89

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  4. Content type: Research article

    Acute tubulointerstitial nephritis (ATIN) is an important cause of acute kidney injury and often a potentially reversible disease. However, the role of steroids in ATIN remains controversial and the underlying...

    Authors: Donghwan Yun, Myoung-jin Jang, Jung Nam An, Jung Pyo Lee, Dong Ki Kim, Ho Jun Chin, Yon Su Kim, Dong-Sup Lee and Seung Seok Han

    Citation: BMC Nephrology 2019 20:88

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  5. Content type: Case report

    Dasatinib is a second-generation tyrosine kinase inhibitor that is indicated for the treatment of patients with chronic myeloid leukemia. Here, we report the case of a man with nephrotic syndrome that was caus...

    Authors: Shoko Ochiai, Yuji Sato, Akihiro Minakawa, Akihiro Fukuda and Shouichi Fujimoto

    Citation: BMC Nephrology 2019 20:87

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  6. Content type: Correction

    Following publication

    Authors: Jan Ebbing, Felix Menzel, Paolo Frumento, Kurt Miller, Bernhard Ralla, Tom Florian Fuller, Jonas Busch, Justin William Collins, Christofer Adding, Hans Helge Seifert, Peter Ardelt, Christian Wetterauer, Timm Westhoff and Carsten Kempkensteffen

    Citation: BMC Nephrology 2019 20:86

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    The original article was published in BMC Nephrology 2019 20:40

  7. Content type: Research article

    Real-world incidence, clinical consequences, and healthcare resource utilization (HRU) of hyperkalemia (HK) remain poorly characterized, particularly in patients with specific comorbidities.

    Authors: Laura Horne, Akhtar Ashfaq, Sharon MacLachlan, Marvin Sinsakul, Lei Qin, Robert LoCasale and James B. Wetmore

    Citation: BMC Nephrology 2019 20:85

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  8. Content type: Research article

    People with Chronic Kidney Disease (CKD) often present with prevalent gait impairment and high fall rates, particularly in advanced CKD stages. Gait impairment and its consequences is associated with increased...

    Authors: Damiano D. Zemp, Olivier Giannini, Pierluigi Quadri and Eling D. de Bruin

    Citation: BMC Nephrology 2019 20:83

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  9. Content type: Research article

    Assessment of adequacy of intermittent hemodialysis (IHD) is conventionally based upon urea kinetic models for calculation of single pool Kt/Vurea (Kt/V), with 1.2 accepted as minimum adequate clearance for thric...

    Authors: Kelly V. Liang, Jane H. Zhang and Paul M. Palevsky

    Citation: BMC Nephrology 2019 20:82

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  10. Content type: Research article

    DOPPS reported that thousands of life-years could be gained in the US and Europe over 5 years by correcting six modifiable haemodialysis practices. We estimated potential life-years gained across 10 European c...

    Authors: Christian Combe, Johannes Mann, David Goldsmith, Frank Dellanna, Philippe Zaoui, Gérard London, Kris Denhaerynck, Andriy Krendyukov, Ivo Abraham and Karen MacDonald

    Citation: BMC Nephrology 2019 20:81

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  11. Content type: Research article

    Hemodialysis patients have high rates of sudden death, but relationships between serum electrolytes, the dialysis prescription, and intra-dialytic shifts in fluid and electrolyte with arrhythmia are uncertain.

    Authors: James A. Tumlin, Prabir Roy-Chaudhury, Bruce A. Koplan, Alexandru I. Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal and David M. Charytan

    Citation: BMC Nephrology 2019 20:80

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  12. Content type: Research article

    It is evident that renal dysfunction (RD) is associated with unique infectious and non-infectious causes in African children. However, little data exists about the prevalence and factors associated with RD in ...

    Authors: Neema Chami, Rogatus Kabyemera, Tulla Masoza, Emmanuela Ambrose, Franscisca Kimaro, Neema Kayange, Adolfine Hokororo, Francis F. Furia and Rob Peck

    Citation: BMC Nephrology 2019 20:79

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  13. Content type: Study protocol

    Five-year survival on dialysis is only 40%, compared to 74% with a deceased donor kidney transplant (DDKT) and 87% with a living donor kidney transplant (LDKT). An American Society of Transplantation (AST) Con...

    Authors: Amy D. Waterman, Crystal Anderson, Angelika Alem, John D. Peipert, Jennifer L. Beaumont, Shayna L. Henry, Bhanuja Dub, Lizeth Ambriz, Neha Bijjala, Amanda Faye Lipsey and Brian Mittman

    Citation: BMC Nephrology 2019 20:78

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  14. Content type: Research article

    IgA nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Urinary micro-RNA (miRNA) level is increasingly reported to as non-invasive markers of various kidney diseases. We aim to identif...

    Authors: Cheuk-Chun Szeto, Gang Wang, Jack Kit-Chung Ng, Bonnie Ching-Ha Kwan, Fernand Mac-Moune Lai, Kai-Ming Chow, Cathy Choi-Wan Luk, Ka-Bik Lai and Philip Kam-Tao Li

    Citation: BMC Nephrology 2019 20:77

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  15. Content type: Research article

    Chronic kidney disease (CKD) is strongly associated with cardiovascular disease and is a significant risk factor for increased morbidity and mortality. In contrast, GLP-1 receptor (GLP-1R) activation has been ...

    Authors: Seung Jung Kim, Soon Kil Kwon, Hye-Young Kim, Sun Moon Kim, Jang-Whan Bae and Joong-Kook Choi

    Citation: BMC Nephrology 2019 20:75

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  16. Content type: Research article

    Exacerbated inflammatory response is considered one of the key elements of acute kidney injury (AKI). Interleukin-6 (IL-6) is an inflammatory cytokine that plays important roles in the inflammatory response an...

    Authors: Takashi Shimazui, Taka-aki Nakada, Yoshihisa Tateishi, Taku Oshima, Tuerxun Aizimu and Shigeto Oda

    Citation: BMC Nephrology 2019 20:74

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  17. Content type: Research article

    Elderly end stage kidney patients face a decision concerning whether or not to initiate dialysis. In Asia, this decision is highly influenced by family caregivers. The objective of this paper was to understand...

    Authors: Semra Ozdemir, Tazeen H. Jafar, Lina Hui Lin Choong and Eric Andrew Finkelstein

    Citation: BMC Nephrology 2019 20:73

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  18. Content type: Research article

    Electronic health record (EHR) based chronic kidney disease (CKD) registries are central to population health strategies to improve CKD care. In 2015, Partners Healthcare System (PHS), encompassing multiple ac...

    Authors: Mallika L. Mendu, Salman Ahmed, Jason K. Maron, Sandhya K. Rao, Sreekanth K. Chaguturu, Megan F. May, Walter P. Mutter, Kelly A. Burdge, David J. R. Steele, David B. Mount, Sushrut S. Waikar, Jeffrey B. Weilburg and Thomas D. Sequist

    Citation: BMC Nephrology 2019 20:72

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  19. Content type: Research article

    Patients with chronic kidney disease (CKD) have a high risk of recurring thrombotic events following acute myocardial infarction (AMI). Microparticles (MPs) are circulating small vesicles shed from various cel...

    Authors: Josefin Mörtberg, Kristina Lundwall, Fariborz Mobarrez, Håkan Wallén, Stefan H. Jacobson and Jonas Spaak

    Citation: BMC Nephrology 2019 20:71

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  20. Content type: Research article

    Alport syndrome is a clinically heterogeneous nephropathy characterized by severe symptomatology at kidney level due to ultrastructural lesions of the glomerular basement membrane (GBM) as consequence of mutat...

    Authors: S. Daga, C. Fallerini, S. Furini, C. Pecoraro, F. Scolari, F. Ariani, M. Bruttini, M. A. Mencarelli, F. Mari, A. Renieri and A. M. Pinto

    Citation: BMC Nephrology 2019 20:70

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  21. Content type: Case report

    Genvoya® (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide) is a recent single regimen for the treatment of Human Immunodeficiency Virus (HIV). However, because of its complexity, it is difficult to...

    Authors: Rita Godinho, Serge Bugnon, Terezija Gracin and James Tataw

    Citation: BMC Nephrology 2019 20:69

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  22. Content type: Research article

    Infections are the second leading cause of death and hospitalisation among haemodialysis (HD) patients. Rates of access-related bloodstream infections (AR-BSI) are influenced by patient characteristics and loc...

    Authors: Husham Mohamed, Alaa Ali, Leonard D. Browne, Nuala H. O’Connell, Liam Casserly, Austin G. Stack and Wael F. Hussein

    Citation: BMC Nephrology 2019 20:68

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  23. Content type: Research article

    Epidemiologic data of acute kidney injury (AKI) during pregnancy is lacking in China. This study aims to determine the effect of pregnancy on the risk of AKI among hospitalized women of childbearing age, and t...

    Authors: Diankun Liu, Wenjuan He, Yanqin Li, Mengqi Xiong, Long Wang, Jingxin Huang, Ling Jia, Shuling Yuan and Sheng Nie

    Citation: BMC Nephrology 2019 20:67

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  24. Content type: Research article

    Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and is characterized by gradual cyst growth and expansion, increase in kidney volume with an ultimate decline i...

    Authors: Kyoungmi Kim, Josephine F. Trott, Guimin Gao, Arlene Chapman and Robert H. Weiss

    Citation: BMC Nephrology 2019 20:66

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  25. Content type: Research article

    Annual influenza vaccination is recommended for all children with idiopathic nephrotic syndrome (INS) in France. Consequently, the Social Security automatically sends prescriptions to all patients suffering fr...

    Authors: Roman Klifa, Julie Toubiana, Alizée Michel, Nathalie Biebuyck, Marina Charbit, Laurence Heidet, Saoussen Krid, Pauline Krug, Rémi Salomon and Olivia Boyer

    Citation: BMC Nephrology 2019 20:65

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  26. Content type: Case report

    Renal artery stenosis is one of the secondary causes of pediatric hypertension. Cases with critical unilateral renal artery stenosis manifesting with the hyponatremic hypertensive syndrome are rare and a compr...

    Authors: Jhao-Jhuang Ding, Shih-Hua Lin, Jin-Yao Lai, Tai-Wei Wu, Jing-Long Huang, Hung-Tao Chung and Min-Hua Tseng

    Citation: BMC Nephrology 2019 20:64

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  27. Content type: Research article

    Hemodialysis patients suffer from a serious threat of cerebrovascular disease. Klotho, as an aging-suppressor gene, contributes to protect on vascular calcification and oxidative stress, which are the risk fac...

    Authors: Honglan Wei, Hua Li, Xiaohong Song, Xingguo Du, Yuan Cai, Chengxu Li, Liping Dong and Junwu Dong

    Citation: BMC Nephrology 2019 20:63

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  28. Content type: Research article

    Circulating C3 has been associated with diabetes and hypertension, which are the leading causes of chronic kidney disease (CKD). C3 activation is considered to contribute to several renal diseases. Here we exa...

    Authors: Xue Bao, Yan Borné, Iram Faqir Muhammad, Christina-Alexandra Schulz, Margaretha Persson, Marju Orho-Melander, Kaijun Niu, Anders Christensson and Gunnar Engström

    Citation: BMC Nephrology 2019 20:61

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  29. Content type: Research article

    Insulin resistance contributes to the metabolic syndrome, which is associated with the development of kidney disease. However, it is unclear if insulin resistance independently contributes to an increased risk...

    Authors: Sarah J. Schrauben, Christopher Jepson, Jesse Y. Hsu, F. Perry Wilson, Xiaoming Zhang, James P. Lash, Bruce M. Robinson, Raymond R. Townsend, Jing Chen, Leon Fogelfeld, Patricia Kao, J. Richard Landis, Daniel J. Rader, L. Lee Hamm, Amanda H. Anderson and Harold I. Feldman

    Citation: BMC Nephrology 2019 20:60

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  30. Content type: Research article

    Risk of cardiac events and cardiovascular disease (CVD) in end-stage renal disease (ESRD) patients are predicted by coronary artery calcification (CAC) independently. It is not clear to what extent low bone mi...

    Authors: Zhimin Chen, Abdul Rashid Qureshi, Torkel B. Brismar, Jonaz Ripsweden, Mathias Haarhaus, Peter Barany, Olof Heimburger, Bengt Lindholm and Peter Stenvinkel

    Citation: BMC Nephrology 2019 20:59

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  31. Content type: Research article

    Intravenous pulse methylprednisolone (MP) is commonly included in the management of severe ANCA associated vasculitis (AAV) despite limited evidence of benefit. We aimed to evaluate outcomes in patients who ha...

    Authors: Dimitrios Chanouzas, Julie Anne G. McGregor, Peter Nightingale, Alan D. Salama, Wladimir M. Szpirt, Neil Basu, Matthew David Morgan, Caroline J. Poulton, Juliana Bordignon Draibe, Elizabeth Krarup, Paula Dospinescu, Jessica Anne Dale, William Franklin Pendergraft, Keegan Lee, Martin Egfjord, Susan L. Hogan…

    Citation: BMC Nephrology 2019 20:58

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  32. Content type: Research article

    Protein-bound uremic toxins are associated with poor outcomes in patients with chronic kidney disease. The aim of this study is to investigate the relationship between indoxyl sulfate (IS), a protein-bound sol...

    Authors: Wenji Wang, Guihua Hao, Yu Pan, Shuai Ma, Tianye Yang, Peng Shi, Qiuyu Zhu, Yingxin Xie, Shaojun Ma, Qi Zhang, Hong Ruan and Feng Ding

    Citation: BMC Nephrology 2019 20:57

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  33. Content type: Research article

    The incidence of Acute Kidney Injury (AKI) continues to increase in the UK, with associated mortality rates remaining significant. Approximately one fifth of hospital admissions are associated with AKI and app...

    Authors: Anastasios Argyropoulos, Stuart Townley, Paul M. Upton, Stephen Dickinson and Adam S. Pollard

    Citation: BMC Nephrology 2019 20:56

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  34. Content type: Research article

    Sarcopenia, defined as low muscle mass and strength, is highly prevalent in patients undergoing chronic hemodialysis (HD). However, muscle function and muscle mass do not share the same clinical relevance. In ...

    Authors: Yu-Li Lin, Shu-Yuan Chen, Yu-Hsien Lai, Chih-Hsien Wang, Chiu-Huang Kuo, Hung-Hsiang Liou and Bang-Gee Hsu

    Citation: BMC Nephrology 2019 20:54

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  35. Content type: Case report

    Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMIGD) is a disease entity classified under the group of “Monoclonal gammopathy-related kidney diseases”, and can recur after transplant. Clinic...

    Authors: Jon Von Visger, Clarissa Cassol, Uday Nori, Gerardo Franco-Ahumada, Tibor Nadasdy and Anjali A. Satoskar

    Citation: BMC Nephrology 2019 20:53

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  36. Content type: Research article

    The survival rate for dialysis patients is poor. Previous studies have shown improved survival with home hemodialysis (HHD), but this could be due to patient selection, since HHD patients tend to be younger an...

    Authors: Helena Rydell, Kerstin Ivarsson, Martin Almquist, Mårten Segelmark and Naomi Clyne

    Citation: BMC Nephrology 2019 20:52

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  37. Content type: Research article

    Post transplantation anemia (PTA) is common among kidney transplant patients. PTA is associated with increased graft loss and in most studies with increased mortality. However, the effect of the severity of an...

    Authors: Amir Schechter, Anat Gafter-Gvili, Daniel Shepshelovich, Ruth Rahamimov, Uzi Gafter, Eytan Mor, Avry Chagnac and Benaya Rozen-Zvi

    Citation: BMC Nephrology 2019 20:51

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  38. Content type: Correction

    Following publication of the original article [1], it was reported that, due to a typesetting mistake, the three tables and two figures for this article were included as an Additional file instead of in the bo...

    Authors: Ziyong Tang, Yue Wang, Liyuan Tao, Yanhong Guo, Yimu Zheng and Danxia Zheng

    Citation: BMC Nephrology 2019 20:50

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    The original article was published in BMC Nephrology 2018 19:357

  39. Content type: Research article

    Magnesium lithospermate B (MLB) can promote renal microcirculation. The aim of the current project was to study whether MLB improves renal hemodynamics, oxygen consumption and subsequently attenuates hypoxia i...

    Authors: Pinglan Lin, Ming Wu, Junyan Qin, Jing Yang, Chaoyang Ye and Chen Wang

    Citation: BMC Nephrology 2019 20:49

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  40. Content type: Research article

    Adherence to the diet prescription for chronic kidney disease is suboptimal. Interventions to improve dietary adherence suggest that improving communication between the patient and the health professional is f...

    Authors: Kelly Lambert, Tsz Kwan Lau, Sarah Davison, Holly Mitchell, Alex Harman and Mandy Carrie

    Citation: BMC Nephrology 2019 20:48

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  41. Content type: Research article

    Volume overload and depletion both lead to high morbidity and mortality. Achieving euvolemia is a challenge in patients with end stage kidney disease on hemodialysis (HD). Blood volume analysis (BVA) uses radi...

    Authors: Line Malha, Hasan Fattah, Frank Modersitzki and David S. Goldfarb

    Citation: BMC Nephrology 2019 20:47

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  42. Content type: Research article

    The magnitude of renal function recovery after kidney donation differs in donors with a heterogeneous background. Preoperative assessment of candidates with potentially unfavorable renal functional compensatio...

    Authors: Kazunobu Shinoda, Shinya Morita, Hirotaka Akita, Satoshi Tamaki, Ryohei Takahashi, Hidaka Kono, Hiroshi Asanuma, Eiji Kikuchi, Masahiro Jinzaki, Ken Nakagawa and Mototsugu Oya

    Citation: BMC Nephrology 2019 20:46

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  43. Content type: Research article

    Nephrotic syndrome (NS) is one of the most frequent occurring chronic kidney diseases in childhood, despite its rarely occurrence in the general population. Detailed information about clinical data of NS (e.g....

    Authors: Ingo Franke, Malik Aydin, Lisa Kurylowicz, Corinna Elke Llamas Lopez, Rainer Ganschow, Michael J. Lentze and Mark Born

    Citation: BMC Nephrology 2019 20:45

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  44. Content type: Research article

    The aim of this study was to assess, the efficacy and safety of add-on corticosteroids to antiretroviral therapy [ART] in patients with biopsy proven HIV associated nephropathy.

    Authors: Nicola Wearne, Charles R. Swanepoel, Maureen S. Duffield, Bianca J. Davidson, Kathryn Manning, Nicki Tiffin, Andrew Boulle, Brian L. Rayner, Priyanka Naidu and Ikechi G. Okpechi

    Citation: BMC Nephrology 2019 20:44

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  45. Content type: Case report

    Thrombospondin type-1 domain-containing 7A (THSD7A) is a target antigen in idiopathic membranous nephropathy (MN). Patients with THSD7A-associated MN are known to have a high possibility of developing malignan...

    Authors: Shinya Taguchi, Yoshiki Koshikawa, Shoya Ohyama, Hiroko Miyachi, Hiroaki Ozawa and Hiroaki Asada

    Citation: BMC Nephrology 2019 20:43

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  46. Content type: Research article

    Pruritus is a distressing, life-limiting symptom in chronic renal failure, affecting 40% of patients. This study aimed to determine uremic pruritus prevalence and investigate the multidimensional impact on hem...

    Authors: Nese Altınok Ersoy and İmatullah Akyar

    Citation: BMC Nephrology 2019 20:42

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