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  1. Heart rhythm complexity, a measure of heart rate dynamics and a risk predictor in various clinical diseases, has not been systematically studied in patients with end-stage renal disease. The aim of this study ...

    Authors: Hongyun Liu, Ping Zhan, Jinlong Shi, Minlu Hu, Guojing Wang and Weidong Wang

    Citation: BMC Nephrology 2020 21:536

    Content type: Research article

    Published on:

  2. An increase of the frequency of uric acid urinary stones compared to calcium-containing ones has been recently described. This study was aimed at assessing the frequency of different types of urinary stones in...

    Authors: Alberto Trinchieri, Alessandro Maletta, Giovanni Simonelli, Luca Boeri, Elisa De Lorenzis and Emanuele Montanari

    Citation: BMC Nephrology 2020 21:535

    Content type: Research article

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  3. Patients with chronic kidney disease (CKD) and arterial calcification are considered at increased risk of adverse cardiovascular outcomes. However, the optimal site for measurement of arterial calcification ha...

    Authors: Ida Maria Hjelm Sørensen, Sasha Asbøll Kepler Saurbrey, Henrik Øder Hjortkjær, Philip Brainin, Nicholas Carlson, Ellen Linnea Freese Ballegaard, Anne-Lise Kamper, Christina Christoffersen, Bo Feldt-Rasmussen, Klaus Fuglsang Kofoed and Susanne Bro

    Citation: BMC Nephrology 2020 21:534

    Content type: Research article

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  4. Patients undergoing haemodialysis (HD) are at higher risk of developing worse outcomes if they contract COVID-19. In our renal service we reduced HD frequency from thrice to twice-weekly in selected patients w...

    Authors: Michelle Da Silva Lodge, Thilini Abeygunaratne, Helen Alderson, Ibrahim Ali, Nina Brown, Constantina Chrysochou, Rosie Donne, Ibi Erekosima, Philip Evans, Emma Flanagan, Simon Gray, Darren Green, Janet Hegarty, Audrey Hyde, Philip A. Kalra, Elizabeth Lamerton…

    Citation: BMC Nephrology 2020 21:532

    Content type: Research article

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  5. The prevalence of chronic kidney disease is on the rise globally and in sub-Saharan Africa. Due to its “silent” nature, many patients often present with advanced disease. At this point options for care are oft...

    Authors: Peace Bagasha, Mhoira Leng, Elly Katabira and Mila Petrova

    Citation: BMC Nephrology 2020 21:531

    Content type: Study protocol

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  6. The iron-based phosphate binder (PB), sucroferric oxyhydroxide (SFOH), demonstrated its effectiveness for lowering serum phosphate levels, with low daily pill burden, in clinical trials of dialysis patients wi...

    Authors: Rosa Ramos, Charles Chazot, Anibal Ferreira, Attilio Di Benedetto, Konstantin Gurevich, Astrid Feuersenger, Melanie Wolf, Hans-Jürgen Arens, Sebastian Walpen and Stefano Stuard

    Citation: BMC Nephrology 2020 21:530

    Content type: Research article

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  7. Dialysis recovery time (DRT) surveys capture the perceived time after HD to return to performing regular activities. Prior studies suggest the majority of HD patients report a DRT > 2 h. However, the profiles ...

    Authors: Murilo Guedes, Roberto Pecoits-Filho, Juliana El Ghoz Leme, Yue Jiao, Jochen G. Raimann, Yuedong Wang, Peter Kotanko, Thyago Proença de Moraes, Ravi Thadhani, Franklin W. Maddux, Len A. Usvyat and John W. Larkin

    Citation: BMC Nephrology 2020 21:529

    Content type: Research article

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  8. Idiopathic multicentric Castleman disease (iMCD) is an uncommon lymphoproliferative disorder and lacks treatment consensus. Herein, we report a case of iMCD complicated with Sjögren’s syndrome (SS) and seconda...

    Authors: Yuejuan Pan, Zhuan Cui, Song Wang, Danxia Zheng, Zhenling Deng, Xinyu Tian, Hongxia Guo, Wenhan Bao, Sijia Zhou and Yue Wang

    Citation: BMC Nephrology 2020 21:528

    Content type: Case report

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  9. Hydrogen sulfide (H2S) has been shown to inhibit the atherosclerosis development and progression. It is produced by cystathionine γ-lyase (CSE) in the cardiovascular system. In our previous study, it has been sho...

    Authors: Xiangxue Lu, Shixiang Wang, Sujuan Feng and Han Li

    Citation: BMC Nephrology 2020 21:527

    Content type: Research article

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  10. Delayed graft function (DGF) is closely associated with the use of marginal donated kidneys due to deficits during transplantation and in recipients. We aimed to predict the incidence of DGF and evaluate its e...

    Authors: Rao Chen, Haifeng Wang, Lei Song, Jianfei Hou, Jiawei Peng, Helong Dai and Longkai Peng

    Citation: BMC Nephrology 2020 21:526

    Content type: Research article

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  11. Tunneled catheters can be used as an alternative vascular access in patients with limited health expectancy,vascular access problems and several comorbidities. We aimed to present a patient with venous stenosi...

    Authors: Sumeyra Koyuncu, Nevzat Herdem, Cihan Uysal, Guven Kahriman, Ismail Kocyigit, Murat Sipahioğlu, Bulent Tokgoz and Oktay Oymak

    Citation: BMC Nephrology 2020 21:525

    Content type: Case report

    Published on:

  12. The separate and combined effects of intradialytic exercise training (IET) and cold dialysis (CD) on patient thermoregulation remain unknown. This study assessed the thermoregulatory responses of hemodialysis ...

    Authors: Argyro A. Krase, Andreas D. Flouris, Christina Karatzaferi, Christoforos D. Giannaki, Ioannis Stefanidis and Giorgos K. Sakkas

    Citation: BMC Nephrology 2020 21:524

    Content type: Research article

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  13. Determination of risks for chronic kidney disease (CKD) progression could improve strategies to reduce progression to ESKD. The eGFR Study recruited a cohort of adult Aboriginal and Torres Strait Islander peop...

    Authors: Sandawana William Majoni, Federica Barzi, Wendy Hoy, Richard J. MacIsaac, Alan Cass, Louise Maple-Brown and Jaquelyne T. Hughes

    Citation: BMC Nephrology 2020 21:523

    Content type: Research article

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  14. Fluid overload is common in patients in the intensive care unit (ICU) and ultrafiltration (UF) is frequently required. There is lack of guidance on optimal UF practice. We aimed to explore patterns of UF pract...

    Authors: Nuttha Lumlertgul, Raghavan Murugan, Nina Seylanova, Patricia McCready and Marlies Ostermann

    Citation: BMC Nephrology 2020 21:522

    Content type: Research article

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  15. Malnutrition, inflammation, and the combination thereof are predictors of poor outcomes in haemodialysis patients. Malnutrition Inflammation Complex Syndrome (MICS) is an accelerator of atherosclerosis and por...

    Authors: Puneet K. Bramania, Paschal Ruggajo, Rimal Bramania, Muhiddin Mahmoud and Francis F. Furia

    Citation: BMC Nephrology 2020 21:521

    Content type: Research article

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  16. Approximately 30% of children with idiopathic nephrotic syndrome develop a complicated course with frequent relapses or steroid dependency. Rituximab, a B cell depleting monoclonal antibody, is a safe and effe...

    Authors: Biswanath Basu, Stella Preussler, Anja Sander, T. K. S. Mahapatra and Franz Schaefer

    Citation: BMC Nephrology 2020 21:520

    Content type: Study protocol

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  17. Glucocorticoids may impact the accuracy of serum cystatin C (sCysC) in reflecting renal function. We aimed to assess the effect of glucocorticoids on the performance of sCysC in detecting acute kidney injury (...

    Authors: Silin Liang, Mai Shi, Yunpeng Bai, Yujun Deng, Miaoxian Fang, Jiaxin Li, Yijin Wu, Wenying Peng, Yating Hou, Heng Fang, Huidan Zhang and Chunbo Chen

    Citation: BMC Nephrology 2020 21:519

    Content type: Research article

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  18. End stage renal disease (ESRD) describes the most severe stage of chronic kidney disease (CKD), when patients need dialysis or renal transplant. There is often a delay in recognizing, diagnosing, and treating ...

    Authors: Zvi Segal, Dan Kalifa, Kira Radinsky, Bar Ehrenberg, Guy Elad, Gal Maor, Maor Lewis, Muhammad Tibi, Liat Korn and Gideon Koren

    Citation: BMC Nephrology 2020 21:518

    Content type: Research article

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  19. Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardio...

    Authors: Samuel A. Headley, Donna J. Chapman, Michael J. Germain, Elizabeth E. Evans, Jasmin Hutchinson, Karen L. Madsen, Talat Alp Ikizler, Emily M. Miele, Kristyn Kirton, Elizabeth O’Neill, Allen Cornelius, Brian Martin, Bradley Nindl and Nosratola D. Vaziri

    Citation: BMC Nephrology 2020 21:517

    Content type: Study protocol

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  20. Glomerular disease patients have a high risk of infection, which contributes to the progression of disease per se and mortality, especially in those with long-term use of glucocorticoids and (or) immunosuppres...

    Authors: Yuzhang Han, Zineng Huang, Huifang Zhang, Liyu He, Lin Sun, Yu Liu, Fuyou Liu and Li Xiao

    Citation: BMC Nephrology 2020 21:516

    Content type: Research article

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  21. End-stage renal disease (ESRD) patients are at a substantially higher risk for developing cognitive impairment compared with the healthy population. Dialysis is an essential way to maintain the life of ESRD pa...

    Authors: Shaohui Ma, Ming Zhang, Yang Liu, Dun Ding, Peng Li, Xueying Ma, Hongjuan Liu and Junya Mu

    Citation: BMC Nephrology 2020 21:515

    Content type: Research article

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  22. A renal biopsy is needed to define active inflammatory infiltration and guide therapeutic management in drug-induced acute tubulointerstitial nephritis (D-ATIN). However, factors such as various contraindicati...

    Authors: Xi-zi Zheng, Yang-hui Gu, Tao Su, Xu-jie Zhou, Jun-wen Huang, Ping-ping Sun, Yan Jia, Da-min Xu, Su-xia Wang, Gang Liu and Li Yang

    Citation: BMC Nephrology 2020 21:514

    Content type: Research article

    Published on:

  23. Reduction in bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) occurs in secondary hyperparathyroidism associated with chronic kidney disease. BMD generally increases following para...

    Authors: Raymond Lin, Mirna Vucak-Dzumhur and Grahame J. Elder

    Citation: BMC Nephrology 2020 21:513

    Content type: Case report

    Published on:

  24. In this study, we focused on the role of overhydration (OH) and low serum prealbumin concentration in predicting peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients over a 3-year period.

    Authors: Quyen Dao Bui Quy, Tuan Pham Ngoc Huy, Loc Nguyen Duc, My Pham Van, Dung Nguyen Huu, Toan Nguyen Duy, Tien Tran Viet, Quyet Do and Thang Le Viet

    Citation: BMC Nephrology 2020 21:512

    Content type: Research article

    Published on:

  25. Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been reported to be associated with inflammation in end-stage renal disease (ESRD) receiving dialysis. However, the value of NLR...

    Authors: Peiyuan Li, Chenqi Xia, Peng Liu, Zhong Peng, Hong Huang, Juan Wu and Zhangxiu He

    Citation: BMC Nephrology 2020 21:511

    Content type: Research article

    Published on:

  26. An association of higher levels of β-hydroxybutyrate (β-HB) in serum with greater mortality in hemodialysis (HD) patients has been reported. This study examined the significance of arterial ketone body ratio (...

    Authors: Masaaki Inaba, Yasuro Kumeda, Shinsuke Yamada, Norikazu Toi, Chie Hamai, Koichi Noguchi, Eikichi Yasuda, Yutaka Furumitsu, Masanori Emoto and Yoshiteru Ohno

    Citation: BMC Nephrology 2020 21:510

    Content type: Research article

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  27. Parents’ adaptation affects the health outcomes of children with chronic kidney diseases (CKD). Identifying factors that affect parents’ adaptation is necessary to understand their adaptation status. This stud...

    Authors: Fatemeh Khorsandi, Naser Parizad, Aram Feizi and Masumeh Hemmati MaslakPak

    Citation: BMC Nephrology 2020 21:509

    Content type: Research article

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  28. Increased right ventricular systolic pressure (RVSP), a surrogate marker for pulmonary hypertension, is common in patients with end-stage kidney disease. Limited data suggest improvement of RVSP with intensive...

    Authors: Michael Girsberger and Christopher T. Chan

    Citation: BMC Nephrology 2020 21:508

    Content type: Research article

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  29. Increase in the number of cases in Chronic Kidney Disease of Unknown etiology (CKDu) in Sri Lanka has become a health issue of national concern. Even though, Northern Province is not identified as a high-risk ...

    Authors: Kalaivani Gobalarajah, Prabagar Subramaniam, Uthpala Apekshani Jayawardena, Gobalarajah Rasiah, Sittampalam Rajendra and Jasotha Prabagar

    Citation: BMC Nephrology 2020 21:507

    Content type: Research article

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  30. Hypertension (HTN) is an established risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). Whether sex differences in the effect of HTN on CKD and ESRD incidence exist remains unclea...

    Authors: Misghina Weldegiorgis and Mark Woodward

    Citation: BMC Nephrology 2020 21:506

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Nephrology 2020 21:545

  31. Metabolic healthy obesity (MHO), a phenotype of obesity, seems to be associated with a lower risk of cardiovascular disease. However, MHO has a close relationship with a higher incidence of metabolic syndrome ...

    Authors: Shasha Yu, Xiaofan Guo, Guang Xiao Li, Hongmei Yang, Liqiang Zheng and Yingxian Sun

    Citation: BMC Nephrology 2020 21:505

    Content type: Research article

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  32. Since the Coronavirus Disease 2019 (COVID-19) outbreak, there is accumulating data on the clinical characteristics, treatment strategies and prognosis of COVID-19 in patients with concurrent renal disease. Pos...

    Authors: Yi Huang, Xiao-Juan Li, Yue-Qiang Li, Wei Dai, Tiffany Shao, Wei-Yong Liu, Min Han, Gang Xu and Liu Liu

    Citation: BMC Nephrology 2020 21:504

    Content type: Case report

    Published on:

  33. Endothelial Progenitor Cells have been shown as effective tool in experimental AKI. Several pharmacological strategies for improving EPC-mediated AKI protection were identified in recent years. Aim of the curr...

    Authors: Daniel Patschan, Katrin Schwarze, Björn Tampe, Jan Ulrich Becker, Samy Hakroush, Oliver Ritter, Susann Patschan and Gerhard Anton Müller

    Citation: BMC Nephrology 2020 21:503

    Content type: Research article

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  34. optimal management of end-stage renal disease (ESRD) in hemodialysis (HD) patients should be more studied because it is a serious risk factor for mortality, being considered an unquestionable global priority.

    Authors: Emily de Souza Ferreira, Tiago Ricardo Moreira, Rodrigo Gomes da Silva, Glauce Dias da Costa, Luciana Saraiva da Silva, Samantha Bicalho de Oliveira Cavalier, Beatriz Oliveira Silva, Heloísa Helena Dias, Luiza Delazari Borges, Juliana Costa Machado and Rosângela Minardi Mitre Cotta

    Citation: BMC Nephrology 2020 21:502

    Content type: Research article

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  35. Kidney allograft survival continuously improved with introduction of novel immunosuppressants. However, also immunologically challenging transplants (blood group incompatibility and sensitized recipients) incr...

    Authors: Miriam Good-Weber, Malgorzata Roos, Thomas F. Mueller, Barbara Rüsi and Thomas Fehr

    Citation: BMC Nephrology 2020 21:501

    Content type: Research article

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  36. Home haemodialysis (HHD), has shown improved clinical outcomes, as well as a better quality of life, compared to conventional in-centre haemodialysis (ICHD) but still has a global low prevalence among end-stag...

    Authors: Natalia Target, Cécile Courivaud, Pierre Antoine Michel, Salima Daoud and Michel Thomas

    Citation: BMC Nephrology 2020 21:500

    Content type: Study protocol

    Published on:

  37. TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organome...

    Authors: Qianyun Zhou, Yuanyuan Zhang, Guangping Zhou and Jihong Zhu

    Citation: BMC Nephrology 2020 21:499

    Content type: Case report

    Published on:

  39. Haemodialysis can negatively impact quality of life and mental health. Arts-based interventions used successfully in other settings to improve health and well-being, could help address the impact of haemodialy...

    Authors: Claire Carswell, Joanne Reid, Ian Walsh, William Johnston, Helen McAneney, Robert Mullan, Jenny B. Lee, Hugh Nelson, Michael Matthews, Elizabeth Weatherup, Andrea Spencer, Jean Michelo, Anne Quail, Grainne Kielty, Alistair Mackenzie, Jenny Elliott…

    Citation: BMC Nephrology 2020 21:497

    Content type: Research article

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  40. Glomerular involvement in rheumatoid arthritis has been known to be associated with treatment side effects from medications and secondary amyloidosis. However, limited basic science and clinical studies have b...

    Authors: Qiyu Wang, Juan P. Ruiz and Peter D. Hart

    Citation: BMC Nephrology 2020 21:496

    Content type: Case report

    Published on:

  41. Chronic kidney disease (CKD) is a significant public health concern. In patients with CKD, interventions that support disease self-management have shown to improve health status and quality of life. At the mom...

    Authors: Hongxia Shen, Rianne van der Kleij, Paul J. M. van der Boog, Xiaoyue Song, Wenjiao Wang, Tongtong Zhang, Zhengyan Li, Xiaoping Lou and Niels Chavannes

    Citation: BMC Nephrology 2020 21:495

    Content type: Study protocol

    Published on:

  42. Chronic kidney disease (CKD), which is characterized by its asymptomatic nature until an end stage, is one of the most common public health problems in the world. Thus, a regular checkup, especially for those ...

    Authors: Meseret Derbew Molla, Maria Degef, Abebe Bekele, Zeleke Geto, Feyissa Challa, Tadesse Lejisa, Tigist Getahun, Meron Sileshi, Yosef Tolcha, Genet Ashebir and Daniel Seifu

    Citation: BMC Nephrology 2020 21:494

    Content type: Research article

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  43. People with chronic kidney disease (CKD) have high levels of co-morbidity and polypharmacy placing them at increased risk of prescribing-related harm. Tools for assessing prescribing safety in the general popu...

    Authors: Fiona Smith, Samantha Hayward, Barnaby Hole, George Kimpton, Christine Sluman, Penny Whiting and Fergus Caskey

    Citation: BMC Nephrology 2020 21:493

    Content type: Research article

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  44. Although young adulthood is associated with transplant loss, many studies do not examine eGFR decline. We aimed to establish clinical risk factors to identify where early intervention might prevent subsequent ...

    Authors: Alexander J. Hamilton, Lucy A. Plumb, Anna Casula and Manish D. Sinha

    Citation: BMC Nephrology 2020 21:492

    Content type: Research article

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  45. Peritoneal dialysis (PD) is a form of therapy for end-stage kidney disease (ESKD), and peritonitis is a known complication. Mycobacterium (M) species associated peritonitis in PD patients is uncommon. Our experie...

    Authors: Anup Singh Jheeta, Jayakeerthi Rangaiah, John Clark, David Makanjuola and Subash Somalanka

    Citation: BMC Nephrology 2020 21:491

    Content type: Case report

    Published on:

  46. In patients with frequently relapsing nephrotic syndrome, immunosuppressive therapy such as cyclosporine are often required to maintain remission. Cyclosporine has been noted to have tumorgenesis effects. In t...

    Authors: Huai-Chueh Gem Wu, Chao-Neng Cheng, Jiann-Shiuh Chen and Yuan-Yow Chiou

    Citation: BMC Nephrology 2020 21:490

    Content type: Case report

    Published on:

  47. The link between dietary protein intake and the risk of kidney dysfunction is always a challenging issue. This study aimed to investigate the relationship between total protein, plant protein, and animal prote...

    Authors: Sevda Alvirdizadeh, Emad Yuzbashian, Parvin Mirmiran, Shahryar Eghtesadi and Fereidoun Azizi

    Citation: BMC Nephrology 2020 21:489

    Content type: Research article

    Published on:

  48. Pregnancy-related Atypical Haemolytic Uremic Syndrome (P-aHUS) is a rare condition affecting genetically predisposed women during pregnancy. It is often difficult to diagnose and has a significant impact on ma...

    Authors: Prianka Puri, Anida Hanxhiu, Daniel V. O’Hara, Danny Hsu and Mirna Vucak-Dzumhur

    Citation: BMC Nephrology 2020 21:488

    Content type: Case report

    Published on:

  50. Chronic kidney disease (CKD) is a global public health concern and diabetes is one of the main risk factors for its occurrence and progression. The aim of this research is to determine the prevalence of chroni...

    Authors: Zaher Nazzal, Zakaria Hamdan, Dunia Masri, Oday Abu-Kaf and Mohammad Hamad

    Citation: BMC Nephrology 2020 21:484

    Content type: Research article

    Published on:

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