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  1. Sarcoidosis is a multisystem inflammatory disorder and can affect any organ; however, ureteric involvement is extremely rare with only four cases reported in the literature to date, all of which were diagnosed...

    Authors: Michikata Hayashida, Akihiro Yano, Kiichi Hagiwara, Shoichi Nagamoto, Kohei Ogawa, Kazushige Sakaguchi, Naoki Sawa, Toshikazu Okaneya and Shinji Urakami
    Citation: BMC Nephrology 2020 21:235
    Content type: Case report Published on:

  2. Arteriosclerosis is prevalent in patients with chronic kidney disease (CKD). Our aims were to investigate (1) the effects of 12 months of either balance- or strength- both in combination with endurance trainin...

    Authors: Yunan Zhou, Matthias Hellberg, Thomas Hellmark, Peter Höglund and Naomi Clyne
    Citation: BMC Nephrology 2020 21:233
    Content type: Research article Published on:

  3. Haemodialysis patients have a high mortality rate. Part of this can be attributed to vascular access complications. Large retrospective studies have shown a higher mortality in patients dialysed with a cathete...

    Authors: Dieter De Clerck, Florence Bonkain, Wilfried Cools and Patricia Van der Niepen
    Citation: BMC Nephrology 2020 21:231
    Content type: Research article Published on:

  4. Low levels of physical activity are implicated in low life expectancies of people receiving maintenance haemodialysis. Accelerometers are increasingly being used to quantify activity behaviours of this populat...

    Authors: Sean Prescott, Jamie P. Traynor, Ilona Shilliday, Tobia Zanotto, Robert Rush and Thomas H. Mercer
    Citation: BMC Nephrology 2020 21:230
    Content type: Research article Published on:

  5. Proteinuria is a major marker of chronic kidney disease (CKD) progression and the predictor of cardiovascular mortality. The rapid development of renal failure is expected in those patients who have higher lev...

    Authors: Abduzhappar Gaipov, Zhandos Utegulov, Rostislav Bukasov, Duman Turebekov, Pavel Tarlykov, Zhannur Markhametova, Zhangatay Nurekeyev, Zhanar Kunushpayeva and Alisher Sultangaziyev
    Citation: BMC Nephrology 2020 21:229
    Content type: Study protocol Published on:

  6. Although the soluble form of suppression of tumorigenicity 2 (sST2) and soluble low-density lipoprotein receptor relative with 11 ligand-binding repeats (sLR11) have emerged as novel cardiovascular biomarkers ...

    Authors: Yu Bum Choi, Mi Jung Lee, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Tae-Hyun Yoo and Hyung Jong Kim
    Citation: BMC Nephrology 2020 21:228
    Content type: Research article Published on:

  7. Acute kidney injury (AKI) occurs in 12–20% of multiple myeloma (MM) patients. Several studies have shown a reduction of free light chains (FLC) using hemodialysis with High-Cut-Off membranes. However, this tec...

    Authors: M. Victoria Pendón-Ruiz de Mier, Raquel Ojeda, M. Antonia Álvarez-Lara, Ana Navas, Corona Alonso, Javier Caballero-Villarraso, Pedro Aljama, Miguel A. Álvarez, Sagrario Soriano, Mariano Rodríguez and Alejandro Martín-Malo
    Citation: BMC Nephrology 2020 21:227
    Content type: Research article Published on:

  8. To investigate the metabolite changes in the frontal lobe of the end-stage renal disease (ESRD) patients with depression using proton magnetic resonance spectroscopy (1H-MRS).

    Authors: Jiachen Wang, Tong Zhou, Jihua Liu, Jingjun Shangguan, Xuejun Liu, Zhiming Li, Xiaoming Zhou, Yande Ren and Chengjian Wang
    Citation: BMC Nephrology 2020 21:225
    Content type: Research article Published on:

  9. Idiopathic membranous nephropathy (IMN) is frequently coexisted with diabetes mellitus (DM). Few researches investigate clinical outcomes in IMN patients coexisting diabetes mellitus (DM), including remission ...

    Authors: Zhiyong Xie, Zhilian Li, Wei Dong, Yuanhan Chen, Ruizhao Li, Yanhua Wu, Huaban Liang, Zhiming Ye, Shuangxin Liu, Wei Shi and Xinling Liang
    Citation: BMC Nephrology 2020 21:224
    Content type: Research article Published on:

  10. Acute kidney injury (AKI) is a common postoperative complication of orthotopic liver transplantation (OLT). So far, little attention has been paid on the association between overweight and AKI after OLT, and a...

    Authors: Jian Zhou, Lin Lyu, Lin Zhu, Yongxin Liang, He Dong and Haichen Chu
    Citation: BMC Nephrology 2020 21:223
    Content type: Research article Published on:

  11. Currently very little is known about the perceptions and experiences of kidney transplant recipients from a qualitative perspective. As highlighted by the European Kidney Health Alliance recommendations, provi...

    Authors: C. McKeaveney, H. Noble, A. E. Courtney, P. Gill, S. Griffin, W. Johnston, A. P. Maxwell, F. Teasdale and J. Reid
    Citation: BMC Nephrology 2020 21:222
    Content type: Study protocol Published on:

  12. The association between glomerulonephritis (GN) and cancer has been well known for decades. However, studies evaluating long-term de novo cancer development in patients with GN are limited. This study aimed to...

    Authors: Hyunjin Ryu, Kipyo Kim, Jiwon Ryu, Hyung-Eun Son, Ji-Young Ryu, Sejoong Kim, Ki Young Na, Dong Wan Chae and Ho Jun Chin
    Citation: BMC Nephrology 2020 21:221
    Content type: Research article Published on:

  13. Post-transplant lymphoproliferative disease is a recognized complication following solid organ transplantation. This is usually a B cell disease and frequently associated with Epstein Barr virus infection, alt...

    Authors: Emily K. Glover, R. Alexander Speight, Despina Televantou, Stephanie Needham and Neil S. Sheerin
    Citation: BMC Nephrology 2020 21:220
    Content type: Case report Published on:

  14. Chronic kidney disease (CKD) disrupts mineral homeostasis and its main underlying cause is secondary hyperparathyroidism (SHPT). We previously reported that calcium-sensing receptor (CaSR) mRNA and protein exp...

    Authors: Taketo Uchiyama, Ichiro Ohkido, Akio Nakashima, Yatsumu Saito, Masataka Okabe and Takashi Yokoo
    Citation: BMC Nephrology 2020 21:219
    Content type: Research article Published on:

  15. The extension of the interdialytic interval due to due to dialysis session non-attendance varies according to which session of the week the patient misses. The impact of this on subsequent hospitalization and ...

    Authors: James Fotheringham, Michael T. Smith, Marc Froissart, Florian Kronenberg, Peter Stenvinkel, Jürgen Floege, Kai-Uwe Eckardt and David C. Wheeler
    Citation: BMC Nephrology 2020 21:218
    Content type: Research article Published on:

  16. There are a growing number of studies on ethnic differences in progression and mortality for pre-dialysis chronic kidney disease (CKD), but this literature has yet to be synthesised, particularly for studies o...

    Authors: Hilda O. Hounkpatin, Simon D. S. Fraser, Rory Honney, Gavin Dreyer, Alison Brettle and Paul J. Roderick
    Citation: BMC Nephrology 2020 21:217
    Content type: Research article Published on:

  17. Chronic kidney disease (CKD) affects drug elimination and patients with CKD require appropriate adjustment of renally cleared medications to ensure safe and effective pharmacotherapy. The main objective of thi...

    Authors: Ronald L. Castelino, Timothy Saunder, Alex Kitsos, Gregory M. Peterson, Matthew Jose, Barbara Wimmer, Masuma Khanam, Woldesellassie Bezabhe, Jim Stankovich and Jan Radford
    Citation: BMC Nephrology 2020 21:216
    Content type: Research article Published on:

  18. There is mounting evidence that individuals with kidney disease and kidney stones have an abnormal gut microbiota composition. No studies to date have summarised the evidence to categorise how the gut microbio...

    Authors: Jordan Stanford, Karen Charlton, Anita Stefoska-Needham, Rukayat Ibrahim and Kelly Lambert
    Citation: BMC Nephrology 2020 21:215
    Content type: Research article Published on:

  19. Patients with end-stage renal disease undergoing chronic hemodialysis (HD) are at high risk to develop tuberculosis (TB) associated with a high mortality rate. TB diagnosis is often delayed due to non-specific...

    Authors: Florence Bonkain, Dieter De Clerck, Violette Dirix, Mahavir Singh, Camille Locht, Françoise Mascart and Véronique Corbière
    Citation: BMC Nephrology 2020 21:214
    Content type: Case report Published on:

  20. Older patients with advanced chronic kidney disease often do not understand treatment options for renal replacement therapy, conservative kidney management, and advance care planning. It is unclear whether bot...

    Authors: Nwamaka D. Eneanya, Allison K. Labbe, Taylor L. Stallings, Shananssa Percy, Jennifer S. Temel, Tamar A. Klaiman and Elyse R. Park
    Citation: BMC Nephrology 2020 21:213
    Content type: Research article Published on:

  21. Anaemia is common in haemodialysis (HD) patients and associated with significant morbidity and mortality. Intravenous (IV) iron combined with erythropoiesis-stimulating agents (ESA) is the mainstay treatment o...

    Authors: Jorge A. Jesus-Silva, Archie Lamplugh, Sameera Dhada, James O. Burton and Sunil Bhandari
    Citation: BMC Nephrology 2020 21:212
    Content type: Research article Published on:

  22. Physical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activ...

    Authors: Keisei Kosaki, Koichiro Tanahashi, Masahiro Matsui, Nobuhiko Akazawa, Yosuke Osuka, Kiyoji Tanaka, David W. Dunstan, Neville Owen, Ai Shibata, Koichiro Oka and Seiji Maeda
    Citation: BMC Nephrology 2020 21:211
    Content type: Research article Published on:

  23. Blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) and diffusion tensor imaging (DTI) are useful methods for investigating the morphology and function of the kidneys, including revealing u...

    Authors: Zhiqiang Wang, Hongxu Liu, Heng Meng and Duo Zhang
    Citation: BMC Nephrology 2020 21:210
    Content type: Research article Published on:

  24. Elevated aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio is an independent risk factor for cardiovascular disease (CVD) among the general population. However, an association between AST/ALT...

    Authors: Xiaoran Feng, Yueqiang Wen, Fen Fen Peng, Niansong Wang, Xiaojiang Zhan and Xianfeng Wu
    Citation: BMC Nephrology 2020 21:209
    Content type: Research article Published on:

  25. The aim of the present study was to evaluate the association between the histology of active and chronic lesions and urinary protein and serum creatinine (SCr) levels, as common clinical endpoints in clinical ...

    Authors: Eri Katsuyama, Yoshia Miyawaki, Ken-ei Sada, Yosuke Asano, Keigo Hayashi, Yuriko Yamamura, Sumie Hiramatsu-Asano, Michiko Morishita, Keiji Ohashi, Haruki Watanabe, Takayuki Katsuyama, Mariko Narazaki, Yoshinori Matsumoto and Jun Wada
    Citation: BMC Nephrology 2020 21:208
    Content type: Research article Published on:

  26. Acute kidney disease (AKD) describes acute or subacute damage and/or loss of kidney function for a duration of between 7 and 90 days after exposure to an acute kidney injury (AKI) initiating event. This study ...

    Authors: Yih-Ting Chen, Chang-Chyi Jenq, Cheng-Kai Hsu, Yi-Ching Yu, Chih-Hsiang Chang, Pei-Chun Fan, Heng-Chih Pan, I-Wen Wu, Wen-Jin Cherng and Yung-Chang Chen
    Citation: BMC Nephrology 2020 21:207
    Content type: Research article Published on:

  27. Previous study showed that purinergic P2X7 receptors (P2X7R) reach the highest expression in the first week after unilateral ureteral obstruction (UUO) in mice, and are involved in the process of inflammation,...

    Authors: José Monteiro Sad Pereira, André Luis Barreira, Conrado Rodrigues Gomes, Felipe Mateus Ornellas, Débora Santos Ornellas, Luiz Carlos Miranda, Lucio Ronaldo Cardoso, Robson Coutinho-Silva, Alberto Schanaider, Marcelo M. Morales, Maurilo Leite Jr and Christina Maeda Takiya
    Citation: BMC Nephrology 2020 21:206
    Content type: Research article Published on:

  28. Peritoneal dialysis (PD) is a home-based therapy performed by patients or their relatives in numerous cases, and the role of patients’ educational practices in the risk of peritonitis is not well assessed. Our...

    Authors: Hélène Bonnal, Clémence Bechade, Annabel Boyer, Thierry Lobbedez, Sonia Guillouët, Christian Verger, Maxence Ficheux and Antoine Lanot
    Citation: BMC Nephrology 2020 21:205
    Content type: Research article Published on:

  29. Thrombotic microangiopathies (TMAs) occurring in the postpartum period may be difficult to manage. They present as the combination of mechanical hemolytic anemia and consumption thrombocytopenia due to endothe...

    Authors: Cyril Mousseaux, Bérangère S. Joly, Inna Mohamadou, Romain Arrestier, Alexandre Hertig and Cédric Rafat
    Citation: BMC Nephrology 2020 21:204
    Content type: Case report Published on:

  30. Patients with chronic kidney disease (CKD) reportedly have a high prevalence of aortic valve calcification (AVC). In population-based studies, AVC is considered a manifestation of systemic atherosclerosis. The...

    Authors: Yui Arita, Masaru Nakayama, Yuta Matsukuma, Ryota Yoshitomi, Makiko Seki, Akiko Fukui, Susumu Tsuda, Yuri Sonoda, Rina Imazu, Kimika Arakawa, Mitsuhiro Tominaga, Toshiaki Nakano, Kazuhiko Tsuruya and Takanari Kitazono
    Citation: BMC Nephrology 2020 21:203
    Content type: Research article Published on:

  31. Urological malignancy (UM) in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. UM is itself a common cause of CKD. Understanding the associations of UM wi...

    Authors: Rajkumar Chinnadurai, Noel W. Clarke and Philip A. Kalra
    Citation: BMC Nephrology 2020 21:202
    Content type: Research article Published on:

  32. Abdominal aortic aneurysms (AAA) primarily affect men over 65 years old who often have many other diseases, with similar risk factors and pathobiological mechanisms to AAA. The aim of this study was to assess ...

    Authors: Milena Miszczuk, Verena Müller, Christian E. Althoff, Andrea Stroux, Daniela Widhalm, Andy Dobberstein, Andreas Greiner, Helena Kuivaniemi and Irene Hinterseher
    Citation: BMC Nephrology 2020 21:201
    Content type: Research article Published on:

  33. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Gregory A. Nichols, Anouk Déruaz-Luyet, Kimberly G. Brodovicz, Teresa M. Kimes, A. Gabriela Rosales and Sibylle J. Hauske
    Citation: BMC Nephrology 2020 21:200
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2020 21:167

  34. A large body mass index (BMI) has been considered as a relative contraindication for percutaneous catheter insertion, although this technique has many advantages. Up to now, there are few studies on peritoneal...

    Authors: Dayang Xie, Jianhui Zhou, Xueying Cao, Qingtao Zhang, Yanli Sun, Li Tang, Jing Huang, Juanli Zheng, Li Lin, Zhenzhen Li, Guangyan Cai and Xiangmei Chen
    Citation: BMC Nephrology 2020 21:199
    Content type: Research article Published on:

  35. To examine the prevalence of chronic kidney disease (CKD) and its associations in a Russian population.

    Authors: Mukharram M. Bikbov, Rinat M. Zainullin, Gyulli M. Kazakbaeva, Timur R. Gilmanshin, Ellina M. Rakhimova, Iulia A. Rusakova, Natalia I. Bolshakova, Kamila R. Safiullina, Songhomitra Panda-Jonas, Dilya F. Yakupova, Nikolai A. Nikitin and Jost B. Jonas
    Citation: BMC Nephrology 2020 21:198
    Content type: Research article Published on:

  36. Physical activity (PA) is typically lower on hemodialysis (HD) days. Albeit intradialytic inactivity is expected, it is unknown whether recovery after HD contributes to low PA. We investigated the impact of HD...

    Authors: John W. Larkin, Maggie Han, Hao Han, Murilo H. Guedes, Priscila Bezerra Gonçalves, Carlos Eduardo Poli-de-Figueiredo, Américo Lourenço Cuvello-Neto, Ana Beatriz L. Barra, Thyago Proença de Moraes, Len A. Usvyat, Peter Kotanko, Maria Eugenia F. Canziani, Jochen G. Raimann and Roberto Pecoits-Filho
    Citation: BMC Nephrology 2020 21:197
    Content type: Research article Published on:

  37. The kidney is a major target in primary antiphospholipid syndrome. Several types of nephropathy have been reported, the most frequent being acute or chronic specific vascular nephropathies and membranous nephr...

    Authors: Maxime Teisseyre, Hélène Perrochia, Pascal Reboul, Sylvain Cariou, Sophie Renaud, Cédric Aglae and Olivier Moranne
    Citation: BMC Nephrology 2020 21:196
    Content type: Case report Published on:

  38. Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been prop...

    Authors: Misa Adachi, Mineaki Kitamura, Kumiko Muta, Akihiro Maekawa, Tadashi Uramatsu, Masato Tadokoro, Satoshi Funakoshi, Satoshi Hisano, Naomi Kuwahara, Akira Shimizu, Hiroshi Mukae and Tomoya Nishino
    Citation: BMC Nephrology 2020 21:195
    Content type: Case report Published on:

  39. Accurate assessment of volume status to direct dialysis remains a clinical challenge. Despite current attempts at volume-directed dialysis, inadequate dialysis and intradialytic hypotension (IDH) are common oc...

    Authors: Bret D. Alvis, Monica Polcz, Merrick Miles, Donald Wright, Mohammad Shwetar, Phil Leisy, Rachel Forbes, Rachel Fissell, Jon Whitfield, Susan Eagle, Colleen Brophy and Kyle Hocking
    Citation: BMC Nephrology 2020 21:194
    Content type: Technical advance Published on:

  41. Kidney transplantation remains the optimal therapy for patients with end stage kidney disease (ESKD), though a small fraction of patients on dialysis are on organ waitlists. An important barrier to both preemp...

    Authors: Samira S. Farouk, Sara Atallah, Kirk N. Campbell, Joseph A. Vassalotti and Jaime Uribarri
    Citation: BMC Nephrology 2020 21:192
    Content type: Research article Published on:

  42. Currently, there is limited epidemiology data on acute kidney injury (AKI) in Indonesia. Therefore, we assessed the incidence of AKI and the utilization of renal replacement therapy (RRT) in Indonesia.

    Authors: Jonny Jonny, Moch Hasyim, Vedora Angelia, Ayu Nursantisuryani Jahya, Lydia Permata Hilman, Venna Febrian Kusumaningrum and Nattachai Srisawat
    Citation: BMC Nephrology 2020 21:191
    Content type: Research article Published on:

  43. Arterial reconstruction is one of the paramount procedures in kidney transplantation (KT) and greatly important if the procured kidney has multiple renal arteries (MRA). Despite various established techniques ...

    Authors: Mitsuru Tomizawa, Shunta Hori, Nobutaka Nishimura, Chihiro Omori, Yasushi Nakai, Makito Miyake, Tatsuo Yoneda and Kiyohide Fujimoto
    Citation: BMC Nephrology 2020 21:190
    Content type: Case report Published on:

  44. Atypical hemolytic uremic syndrome (aHUS) can result in severe kidney dysfunction, secondary to thrombotic microangiopathy. Eculizumab has been used to treat this disorder, and has resulted in favourable outco...

    Authors: Sam Kant, Anshul Bhalla, Sami Alasfar and Nada Alachkar
    Citation: BMC Nephrology 2020 21:189
    Content type: Research article Published on:

  45. There is a lack of empirical effort that systematically investigates the clustering of comorbidity among known risk factors (obesity, hypertension, diabetes, hypercholesterolemia, and elevated inflammation) of...

    Authors: Agus Surachman, Jonathan Daw, Bethany C. Bray, Lacy M. Alexander, Christopher L. Coe and David M. Almeida
    Citation: BMC Nephrology 2020 21:188
    Content type: Research article Published on:

  46. T-type calcium channels (TTCC) are involved in mesangial cell proliferation. In acute thy-1 nephritis in the rat TTCC inhibition reduces glomerular damage and cell proliferation. This work is extended here by ...

    Authors: Andrea Cove-Smith, Claire C. Sharpe, Michael J. Shattock and Bruce M. Hendry
    Citation: BMC Nephrology 2020 21:187
    Content type: Research article Published on:

  47. Glomerulonephritides (GN) are relatively rare kidney diseases with substantial morbidity and mortality. They are often difficult to treat, sometimes with no cure, and can lead to chronic kidney disease (CKD) a...

    Authors: Anas AlYousef, Ali AlSahow, Bassam AlHelal, Ahmed Alqallaf, Emad Abdallah, Mohammed Abdellatif, Hani Nawar and Riham Elmahalawy
    Citation: BMC Nephrology 2020 21:186
    Content type: Research article Published on:

  48. Quality of life (QOL) is important to patients with end stage renal disease and their partners. Despite the first 12 weeks being a critical time in the treatment pathway, limited research exists which examines...

    Authors: Currie Moore, Lesley-Anne Carter, Sandip Mitra, Suzanne Skevington and Alison Wearden
    Citation: BMC Nephrology 2020 21:185
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2020 21:254

  49. Crystalglobulin-associated nephropathy (CAN), a rare subtype of monoclonal gammopathy, usually associated with multiple myeloma and occasionally monoclonal gammopathy of uncertain significance (MGUS), is chara...

    Authors: Rajib K. Gupta, Lois J. Arend, Anupama BK, Sriram Narsipur and Ramya Bhargava
    Citation: BMC Nephrology 2020 21:184
    Content type: Case report Published on:

  50. Continuous ambulatory peritoneal dialysis (CAPD) patients have a high incidence of stroke and commonly have increased parathyroid hormone levels and vitamin D insufficiency. We seek to investigate the incidenc...

    Authors: Xiaohan You, Ying Zhou, Jianna Zhang, Qiongxiu Zhou, Yanling Shi, Zhen Su, Chaoshen Chen, Rongrong Shao and Ji Zhang
    Citation: BMC Nephrology 2020 21:183
    Content type: Research article Published on:
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