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  1. Advanced glycation end products (AGEs) deposited in the lens are correlated with those in the kidneys, indicating a possible value in evaluating diabetic kidney disease (DKD). This study explored the value of ...

    Authors: Xiaodi Zheng, Yuan Gao, Yuhong Huang, Ruihua Dong, Mengxue Yang, Xuemeng Zhang, Miao Zeng, Rui Zhang, Yueyue Wu, Zhiyan Yu, Jun Liu and Bingbing Zha
    Citation: BMC Nephrology 2023 24:379
    Content type: Research Published on:

  2. The most common genetic causes of steroid-resistant nephrotic syndrome (SRNS) are mutations in the NPHS2 gene, which encodes the cholesterol-binding, lipid-raft associated protein podocin. Mass spectrometry and c...

    Authors: Linus Butt, David Unnersjö-Jess, Dervla Reilly, Robert Hahnfeldt, Markus M. Rinschen, Katarzyna Bozek, Bernhard Schermer, Thomas Benzing and Martin Höhne
    Citation: BMC Nephrology 2023 24:378
    Content type: Research Published on:

  3. Chronic renal failure (CRF) is defined by a significant decline in renal function that results in decreased salt filtration and inhibition of tubular reabsorption, which ultimately causes volume enlargement. T...

    Authors: Mahmoud S. Sabra, Fahmy K. Hemida and Essmat A. H. Allam
    Citation: BMC Nephrology 2023 24:377
    Content type: Research Published on:

  4. End-stage kidney disease (ESKD) is associated with increased morbidity and mortality. Identifying patients with stage 4 CKD (CKD4) at risk of rapid progression to ESKD remains challenging. Accurate prediction ...

    Authors: Kullaya Takkavatakarn, Wonsuk Oh, Ella Cheng, Girish N Nadkarni and Lili Chan
    Citation: BMC Nephrology 2023 24:376
    Content type: Research Published on:

  5. Kidney dysfunction is a common, progressive condition that is increasingly becoming a global public health issue. Because the kidneys are the major route for drug excretion, impaired renal function can change ...

    Authors: Julius Kyomya, Fredrick Atwiine, Efrata Ashuro Shegena, Rose Muhindo and Tadele Mekuriya Yadesa
    Citation: BMC Nephrology 2023 24:375
    Content type: Research Published on:

  6. Cardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD) and could be related to oxidative stress. Vascular calcification (VC) has been established...

    Authors: Masa Nakanishi, Ayako Goto, Takahide Iwasaki, Takeshi Nakanishi, Akihiro Kuma, Masayoshi Nanami and Takahiro Kuragano
    Citation: BMC Nephrology 2023 24:373
    Content type: Research Published on:

  7. Although combining a low-protein diet (LPD) with oral nutritional supplements increases treatment adherence and nutritional status in patients with chronic kidney disease (CKD), the effect of this combination ...

    Authors: Wen-Ching Yang, Hui-Min Hsieh, Jun-Peng Chen, Li-Chun Liu and Cheng-Hsu Chen
    Citation: BMC Nephrology 2023 24:372
    Content type: Research Published on:

  8. Frailty increases risk of morbidity and mortality in hemodialysis patients. Frailty assessments could trigger risk reduction interventions if broadly adopted in clinical practice. We aimed to assess the clinic...

    Authors: Anuradha Wadhwa, Salva N. Balbale, Sujith K. Palleti, Manpreet Samra, Reynold I. Lopez-Soler, Kevin T. Stroupe, Talar W. Markossian and Megan Huisingh-Scheetz
    Citation: BMC Nephrology 2023 24:371
    Content type: Research Published on:

  9. Sarcoidosis affects multiple organs and exhibits diverse clinical manifestations. Although tubulointerstitial nephritis is a known feature of renal involvement, necrotizing vasculitis is rare. Furthermore, pro...

    Authors: Arata Osanami, Tomohisa Yamashita, Shintaro Sakurada, Tatsuya Sato, Yuki Kyoda, Tetsuya Shindo, Hiromi Fujita, Yayoi Ogawa and Masato Furuhashi
    Citation: BMC Nephrology 2023 24:370
    Content type: Case Report Published on:

  10. This study aimed to investigate the relationship between the consumption of fresh and salt-preserved vegetables and the estimated glomerular filtration rate (eGFR), which requires further research.

    Authors: Haiqing Zheng, Huixian Li, Liyan Pan, Lianting Hu, Xuanhui Chen, Jiaxin Hou and Huiying Liang
    Citation: BMC Nephrology 2023 24:369
    Content type: Research Published on:

  13. To explore the clinicopathologic features and outcomes of IgAN patients who presented with fibrinoid necrosis (FN) lesions or not and the effect of immunosuppressive (IS) treatment in IgAN patients with FN les...

    Authors: Hongshan Chen, Youxia Liu, Li Wei, He Wang, Zhenfeng Zheng, Tiekun Yan, Junya Jia and Dong Li
    Citation: BMC Nephrology 2023 24:366
    Content type: Research Published on:

  14. Focal segmental glomerulosclerosis (FSGS) is one of the leading causes of nephrotic syndrome in adults. This epidemiological study describes a renal centre’s 20-year experience of primary FSGS.

    Authors: Thomas McDonnell, Joshua Storrar, Rajkumar Chinnadurai, Calvin Heal, Constantina Chrysochou, James Ritchie, Francesco Rainone, Dimitrios Poulikakos, Philip Kalra and Smeeta Sinha
    Citation: BMC Nephrology 2023 24:365
    Content type: Research Published on:

  15. Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease (CVD) and aortic stenosis. However, the data on the relationship between Lp(a) and mildly reduced estimated glomerular filtration rate (eGFR) ...

    Authors: Hong Zhang, Rui Chen, Shoukui Xiang, Pei Gao, Jing Zhu, Long Wang, Xiaohong Jiang, Fei Hua and Xiaolin Huang
    Citation: BMC Nephrology 2023 24:364
    Content type: Research Published on:

  17. Organ measurements derived from magnetic resonance imaging (MRI) have the potential to enhance our understanding of the precise phenotypic variations underlying many clinical conditions.

    Authors: Marjola Thanaj, Nicolas Basty, Madeleine Cule, Elena P. Sorokin, Brandon Whitcher, Ramprakash Srinivasan, Rachel Lennon, Jimmy D. Bell and E. Louise Thomas
    Citation: BMC Nephrology 2023 24:362
    Content type: Research Published on:

  18. Diabetic nephropathy (DN) is a serious chronic complication of diabetes mellitus (DM). Endoplasmic reticulum (ER) stress is an important factor in the regulation of pathological processes in DN, and excessive ...

    Authors: Teng Liu, Yu-qing Jin, Qi Wang, Cong-hui Jia, Wei-yan Ren, Jia-yi Liu, Lei Yang and Hong-min Luo
    Citation: BMC Nephrology 2023 24:361
    Content type: Research Published on:

  19. Growing evidence has demonstrated that patients undergoing peritoneal dialysis (PD) are more likely to experience cognitive impairment than patients with non-dialysis end-stage renal disease (ESRD); however, t...

    Authors: Jingjing Wang, Siyang Wu, Jin Zhang, Yuanyuan Li, Yonggui Wu and Xiangming Qi
    Citation: BMC Nephrology 2023 24:360
    Content type: Research Published on:

  20. Fibronectin glomerulopathy is a rare genetic nephropathy with only a few cases of post-transplant recurrence being reported previously. We highlight a case that was initially misdiagnosed and emphasize the imp...

    Authors: Nathaniel Klair, Salman B. Mahmood, Rasha El-Rifai, Cynthia C. Nast, Lihong Bu and Adam Bregman
    Citation: BMC Nephrology 2023 24:359
    Content type: Case Report Published on:

  21. This study aimed to identify the factors relating to moderately increased albuminuria among middle-aged and older individuals in Japan.

    Authors: Shoichi Fukuda, Ukyo Shirase, Shigeru Ogimoto, Mai Nakagawa, Kazumi Nakagawa, Ayumu Tominaga and Hisayoshi Morioka
    Citation: BMC Nephrology 2023 24:358
    Content type: Research Published on:

  22. Diabetic kidney disease (DKD) is the most common microvascular complication of diabetes, which has been a major cause of end-stage renal failure. Diagnosing diabetic kidney disease is important to prevent long...

    Authors: Xue-hong Zhou, Shu-yan Liu, Bo Yang, Yong-feng Li and Bao-hua Hou
    Citation: BMC Nephrology 2023 24:357
    Content type: Research Published on:

  23. Services for patients with kidney disease underwent radical adaptations in response to the COVID-19 pandemic. We undertook an online national survey of UK kidney centres to understand the nature, range, and de...

    Authors: Lucy Mackintosh, Amanda Busby, Ken Farrington, Janine Hawkins, Sarah Afuwape, Paul Bristow, Maria Da Silva-Gane, Natalie Hall, Tess Harris, Joanna Hudson, Sam Norton, Paula Ormandy, Christina J. Pearce, Shalini Santhakumaran, Shivani Sharma, Sivakumar Sridharan…
    Citation: BMC Nephrology 2023 24:356
    Content type: Research Published on:

  24. Scleroderma renal crisis (SRC) is a critical kidney involvement of systemic sclerosis (SSc), often resulting in end-stage renal disease. Although the recurrence of SRC in the allograft has been reported, the d...

    Authors: Hajime Sanada, Satoshi Hara, Makoto Horita, Hiroyuki Kawahara, Misaki Yoshida, Yoshinori Takahashi, Shunsuke Tsuge, Takeshi Zoshima, Ryo Nishioka, Kiyoaki Ito, Ichiro Mizushima, Takashi Matsushita and Mitsuhiro Kawano
    Citation: BMC Nephrology 2023 24:355
    Content type: Case Report Published on:

  26. Prolonged hemodialysis (HD) is performed from 6 to 12 h and can last up to 24 h. To prevent system clotting some studies suggest that Regional Citrate Anticoagulation (RCA) use reduces bleeding rates relative ...

    Authors: Jorge Alberto Menegasso Vieira, Isabel Cristina Reinheimer, Amanda Corrêa dos Santos, Fernando Kowarick Halperin, Luiza Aguirre Susin, Lia Portella Staub, Raquel Jaqueline Eder Ribeiro, Julia Braga da Silveira, Lucas Friedrich Fontoura, Diego Candido de Souza, Karen Patrícia Nunes, Vandrea Carla de Souza, Luciano da Silva Selistre and Carlos Eduardo Poli-de-Figueiredo
    Citation: BMC Nephrology 2023 24:353
    Content type: Research Published on:

  27. The intricate relationship between hypertension and chronic kidney disease (CKD) presents a global challenge for prevention of hypertension-related CKD. This study’s objective is to analyze age, gender, region...

    Authors: Yan Liu, Qin He, Qiying Li, Min Tian, Xiaojiao Li, Xufeng Yao, Dongmei He and Chunying Deng
    Citation: BMC Nephrology 2023 24:352
    Content type: Research Published on:

    The Correction to this article has been published in BMC Nephrology 2024 25:11

  28. Nephropathic Cystinosis (NC), a rare disease characterised by intra-lysosomal accumulation of cystine, results in progressive kidney failure (KF). Compliance to lifelong oral cysteamine, the only therapy, is o...

    Authors: Seun Lashilola, Weiwei Xu, Khashayar Azimpour, Michael McCarthy, Sara Carlot, David Game and Judith van der Voort
    Citation: BMC Nephrology 2023 24:351
    Content type: Research Published on:

  29. Disability in activities of daily living (ADL) significantly increases the risk of mortality among patients undergoing hemodialysis. Malnutrition and decreased exercise capacity are closely correlated with ADL...

    Authors: Junhui Li, Zhi Wang, Qiannan Zhang, Huiping Zhang, Yuxin Shen, Qi Zhang, Guihua Jian, Dongsheng Cheng and Niansong Wang
    Citation: BMC Nephrology 2023 24:350
    Content type: Research Published on:

  30. Sickle cell disease is the most common inherited blood disorder in humans and constitutes a major public health burden. It is a multisystemic condition with long-term renal complications. Early detection of si...

    Authors: Hakeem Edun Babatunde, Afeez Oyesola Bello, Muhammed A. Nurudeen Adeboye, Olumuyiwa Shola Folayan, Olugoke Ezekiel Ojewole and Usman Abubakar
    Citation: BMC Nephrology 2023 24:349
    Content type: Research Published on:

  32. Kidney failure is one of the leading causes of morbidity and mortality worldwide. The incidence of kidney failure in Somalia has been increasing in recent years. There is no data available on the causes of chr...

    Authors: Hamze Ibrahim Rage, Suleyman A Ers, Abdirazak Y Kahin, Muraad M Elmi, Abdiaziz A Mohamed and Pranaw Kumar Jha
    Citation: BMC Nephrology 2023 24:347
    Content type: Research Published on:

  33. Kidney transplantation is the optimal treatment option for most patients with end-stage kidney disease given the significantly lower morbidity and mortality rates compared to remaining on dialysis. Rejection a...

    Authors: Anna Rainey, Gareth J. McKay, Jane English, Ammarin Thakkinstian, Alexander Peter Maxwell and Michael Corr
    Citation: BMC Nephrology 2023 24:346
    Content type: Research Published on:

  34. Patients with kidney failure on hemodialysis (HD) experience considerable symptom burden and poor health-related quality of life (HRQoL). There is limited use of patient reported outcome measures (PROMs) in fa...

    Authors: Neeru Agarwal, Karan K. Shah, Kathryn Dansie, Paul N. Bennett, Lavern Greenham, Chris Brown, Brendan Smyth, Stephen McDonald, Shilpanjali Jesudason, Andrea K. Viecelli and Rachael L. Morton
    Citation: BMC Nephrology 2023 24:345
    Content type: Research Published on:

  35. Fabry disease (FD) is an X-linked inherited lysosomal disorder due to a deficiency of the enzyme alpha-galactosidase A (α-gla) due to mutations in the GLA gene. These mutations result in plasma and lysosome ac...

    Authors: Pasquale Esposito, Carmela Caputo, Monica Repetto, Alberto Somaschini, Bellone Pietro, Paolo Colomba, Carmela Zizzo, Angelica Parodi, Valentina Zanetti, Marco Canepa, Virginia Eustachi, Francesca Sanguineri, Paola Mandich and Francesca Viazzi
    Citation: BMC Nephrology 2023 24:344
    Content type: Review Published on:

  36. Although Acute Kidney Injury (AKI) incidence is increasing worldwide, data investigating its cost are lacking. This population-wide study aimed to describe the characteristics and costs of hospital stays with,...

    Authors: Céline Monard, Thomas Rimmelé, Esther Blanc, Mélanie Goguillot, Stève Bénard and Julien Textoris
    Citation: BMC Nephrology 2023 24:343
    Content type: Research Published on:

  37. Identifying age-related trend of estimated glomerular filtration rate (eGFR) is necessary to assess whether kidney function is healthily aging. This study aimed to investigate the application of CKD-EPI, FAS, ...

    Authors: Lu Wei, Xue Shen, Juan Zhang, Zhenzhu Yong, Qun Zhang and Weihong Zhao
    Citation: BMC Nephrology 2023 24:342
    Content type: Research Published on:

  38. Despite the recognized high symptom prevalence in haemodialysis population, how these symptoms change over time and its implications for clinical practice and research is poorly understood.

    Authors: Pann Ei Hnynn Si, Mónica Hernández-Alava, Louese Dunn, Martin Wilkie and James Fotheringham
    Citation: BMC Nephrology 2023 24:341
    Content type: Research Published on:

  39. Culture-negative peritonitis is a serious complication in patients undergoing maintenance peritoneal dialysis (PD) and occurs in up to 40% of all peritonitis episodes. Despite its high incidence, data regardin...

    Authors: Kittiphan Chienwichai, Sorawat Sangaew, Laksamee Chuachanpipat and Arunchai Chang
    Citation: BMC Nephrology 2023 24:340
    Content type: Research Published on:

  40. Mortality is high within the first few months of starting chronic dialysis. Pre-ESKD trajectory of kidney function has been shown to be predictive of early death after dialysis initiation. We aim to better und...

    Authors: Raymond K. Hsu, Anna D. Rubinsky, Michael G. Shlipak, Kirsten L. Johansen, Michelle M. Estrella, Benjamin J. Lee, Carmen A. Peralta and Chi-yuan Hsu
    Citation: BMC Nephrology 2023 24:339
    Content type: Research Published on:

  41. The prevalence of chronic kidney disease (CKD) is rising in Malaysia. Early detection is necessary to prevent disease progression, especially in terms of cardiovascular (CV) risk, the main cause of death in en...

    Authors: Ruslinda Mustafar, Khairun Amalin Mohd Hishamuddin, Rozita Mohd, Lydia Kamaruzaman, Wan Haslina Wan Abdul Halim, Yong Meng Hsien, Tan Kuan Sze, Wan Mimi Diyana Wan Zaki, Aziah Ali and Arbaiyah Bain
    Citation: BMC Nephrology 2023 24:338
    Content type: Research Published on:

  42. Knowledge on prevalence, comorbidities and consequences of chronic kidney disease (CKD) is mandatory to estimate the potential of cardiovascular risk management on a population level. We studied the prevalence...

    Authors: Marc G. Vervloet, Hilda JI de Jong, Jan Pander and Jetty A. Overbeek
    Citation: BMC Nephrology 2023 24:337
    Content type: Research Published on:

  43. Immune thrombocytopenia (ITP) is an acquired disorder characterised by a low platelet count due to immune-mediated destruction and impaired platelet production. Here we report a rare case of primary cytomegalo...

    Authors: Tomohiro Takehara, Hayato Nishida, Kazunobu Ichikawa, Yuka Hosokawa, Takaaki Nawano, Satoshi Takai, Hiroki Fukuhara, Masahito Himuro, Norihiko Tsuchiya and Masafumi Watanabe
    Citation: BMC Nephrology 2023 24:336
    Content type: Case Report Published on:

  44. CKD of unknown etiology (CKDu) disproportionately affects young people in Central America who lack traditional CKD risk factors (diabetes and hypertension) and has instead been variably linked to heat stress, ...

    Authors: Anna Strasma, Ángel Mejía Reyes, Aurora Aragón, Indiana López, Lawrence P. Park, Susan L. Hogan, Nathan Thielman, Christina Wyatt and Marvin González-Quiroz
    Citation: BMC Nephrology 2023 24:335
    Content type: Research Published on:

  45. Continuous renal replacement therapy is a relatively common modality applied to critically ill patients with renal impairment. To maintain stable continuous renal replacement therapy, sufficient blood flow thr...

    Authors: Leerang Lim, Jung Yeon Park, Hannah Lee, Seung-Young Oh, Christine Kang and Ho Geol Ryu
    Citation: BMC Nephrology 2023 24:334
    Content type: Research Published on:

  46. Autosomal-dominant polycystic kidney disease (ADPKD) is the most prevalent hereditary kidney disease and the fourth leading cause of end-stage renal disease (ESRD) requiring renal replacement therapy (RRT). Ne...

    Authors: Li-Chi Chen, Yi-Chi Chu, Tzongshi Lu, Hugo Y.-H. Lin and Ta-Chien Chan
    Citation: BMC Nephrology 2023 24:333
    Content type: Research Published on:

  47. While the association between decreased serum albumin (ALB) levels and increased risk of acute kidney injury (AKI) is well established, the risk of death among patients with AKI with low serum ALB levels is un...

    Authors: Kaibi Yang, Nan Yang, Wenbo Sun, Limiao Dai, Juan Jin, Juan Wu and Qiang He
    Citation: BMC Nephrology 2023 24:332
    Content type: Research Published on:

  48. In renal transplant patients, bisphosphonates may prevent bone loss, but little is known about their effects on bone microarchitecture and geometrical hip parameters, as the key factors of bone stability. This...

    Authors: Alireza Dabbaghmanesh, Marzieh Bakhshayeshkaram, Sharareh Roshanzamir, Arzhang Naseri, Mohammad Mahdi Dabbaghmanesh, Seyed Taghi Heydari, Pedram Talehzadeh, Mohammad Hossein Dabbaghmanesh and Shahrokh Ezzatzadegan Jahromi
    Citation: BMC Nephrology 2023 24:331
    Content type: Research Published on:
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