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  1. Globally, the prevalence of chronic kidney disease (CKD) is higher in women than in men; however, women have been historically under-represented in nephrology clinical trials. Metabolic acidosis increases risk...

    Authors: Vandana S. Mathur, Donald E. Wesson, Navdeep Tangri, Elizabeth Li and David A. Bushinsky
    Citation: BMC Nephrology 2022 23:82
    Content type: Research Published on:

  2. The coronavirus disease 2019 (COVID-19) pandemic has caused significant psychological distress globally. Our study assessed the prevalence of psychological distress and associated factors during COVID-19 pande...

    Authors: Sobhana Thangaraju, Yeli Wang, Terence Kee, Ping Sing Tee, York Moi Lu, Jing Hua Yong, Quan Yao Ho, Ian Tatt Liew, Fiona Foo, Natelie Kwan, Eleanor Ng, Xia He, Constance Lee, Shannon Baey, Jenny Leong, Judy Tan…
    Citation: BMC Nephrology 2022 23:80
    Content type: Research article Published on:

  3. Right ventricular (RV) function is an important prognostic predictor for end-stage renal disease (ESRD) patients. Non-invasive evaluation of RV function by simple electrocardiogram (ECG) is not yet evident. Th...

    Authors: Yunis Daralammouri, Jamal Qaddumi, Khubaib Ayoub, Doaa Abu-Hantash, Mai Arafat Al-sadi, Rofayda M. Ayaseh, Murad Azamtta, Osama Sawalmeh and Zakaria Hamdan
    Citation: BMC Nephrology 2022 23:79
    Content type: Research Published on:

  4. The association between homocysteine (Hcy) and IgA nephropathy (IgAN) is not well understood. We aimed to investigate the relationship between Hcy and clinicopathologic features in IgAN patients.

    Authors: Zizhen Li, Qianqian Han, Hongbo Ye, Jiajia Li, Xiaona Wei, Rui Zhang, Qiuyan Huang, Yanchun Xu, Guanxian Liu, Bin Li and Qiongqiong Yang
    Citation: BMC Nephrology 2022 23:78
    Content type: Research Published on:

  5. Although Brazil has one of the largest populations on haemodialysis (HD) in the world, data regarding patients’ characteristics and the variables associated with risk of death are scanty.

    Authors: Ana Beatriz Lesqueves Barra, Ana Paula Roque-da-Silva, Maria Eugenia F. Canziani, Jocemir R. Lugon and Jorge Paulo Strogoff-de-Matos
    Citation: BMC Nephrology 2022 23:77
    Content type: Research Published on:

  6. Escherichia coli peritonitis (EP) is a serious complication of peritoneal dialysis (PD). Gut microbiota alterations occur in end-stage renal disease (ESRD) patients. The relationship between the gut microbiota a...

    Authors: Jun Zhou, Cuishun Yang, Wenjuan Lei, Zhen Yang, Jianmei Chen, Hua Lin, Qingtian Li and Wanqiong Yuan
    Citation: BMC Nephrology 2022 23:76
    Content type: Research Published on:

  7. Authors: Luke A. Baker, Daniel S. March, Thomas J. Wilkinson, Roseanne E. Billany, Nicolette C. Bishop, Ellen M. Castle, Joseph Chilcot, Mark D. Davies, Matthew P. M. Graham-Brown, Sharlene A. Greenwood, Naushad A. Junglee, Archontissa M. Kanavaki, Courtney J. Lightfoot, Jamie H. Macdonald, Gabriella M. K. Rossetti, Alice C. Smith…
    Citation: BMC Nephrology 2022 23:75
    Content type: Guidelines Published on:

  8. Patients with chronic kidney disease commonly experience gait abnormalities, which predispose to falls and fall-related injuries. An unmet need is the development of improved methods for detecting patients at ...

    Authors: Atsumi Kimura, William Paredes, Rima Pai, Hina Farooq, Rupinder S. Buttar, Matthew Custodio, Samhitha Munugoti, Sonia Kotwani, Lovepreet S. Randhawa, Solomon Dalezman, Antonio C. Elters, Kate Nam, Jose S. Ibarra, Sandheep Venkataraman and Matthew K. Abramowitz
    Citation: BMC Nephrology 2022 23:74
    Content type: Research Published on:

  9. We examined in persons with type 2 diabetes (T2D) whether the use of insulin and the risk of serious hypoglycemic events with insulin is higher in persons with more advanced CKD.

    Authors: Daulton Grube, Guo Wei, Robert Boucher, Nikita Abraham, Na Zhou, Victoria Gonce, Judy Carle, Debra L. Simmons and Srinivasan Beddhu
    Citation: BMC Nephrology 2022 23:73
    Content type: Research Published on:

  10. Instrumental gait analysis in nephrology is widely neglected, although patients with chronic kidney disease (CKD) show brain changes due to cerebrovascular disease and metabolic disorders that can potentially ...

    Authors: Damiano D. Zemp, Olivier Giannini, Pierluigi Quadri, Marco Rabuffetti, Mauro Tettamanti and Eling D. de Bruin
    Citation: BMC Nephrology 2022 23:72
    Content type: Research Published on:

  11. Hemodialysis is the most common treatment of end-stage renal disease. However, it is associated with a range of symptoms affecting patients’ daily activities and quality of life. Effective self-management has ...

    Authors: Yongchao Hou, Li Li, Qian Zhou, Guohong Wang and Rongshan Li
    Citation: BMC Nephrology 2022 23:71
    Content type: Research Published on:

  12. Given the importance of the function of the remnant kidney in children with unilateral renal agenesis and the significance of timely diagnosis and treatment of reflux nephropathy to prevent further damage to t...

    Authors: Maryam Esteghamati, Hadi Sorkhi, Hamid Mohammadjafari, Ali Derakhshan, Simin Sadeghi-Bojd, Hossein Emad Momtaz, Masoumeh Mohkam, Baranak Safaeian, Nakysa Hooman, Afshin Safaeiasl, Mohsen Akhavan Sepahi, Khadijeh Ghasemi, Zahra Bazargani and Elham Emami
    Citation: BMC Nephrology 2022 23:70
    Content type: Research Published on:

  13. Patients with chronic kidney disease (CKD) are at a high risk of fatal arrhythmias. The extended corrected QT (QTc) interval is a hallmark of ventricular arrhythmias and sudden cardiac death. Previous studies ...

    Authors: Wenjing Zhang, Yu Liang, Jia Lv, Yan Li and Jiping Sun
    Citation: BMC Nephrology 2022 23:69
    Content type: Research article Published on:

  14. Little is known about the association between the coexistence of diabetes mellitus (DM) and pre-existing cardiovascular disease (CVD) and mortality in patients undergoing continuous ambulatory peritoneal dialy...

    Authors: Guangtao Lei, Xiaoran Feng, Xiaoyang Wang, Yueqiang Wen, FenFen Peng, Niansong Wang, Xiaojiang Zhan, Qinghua Wu and Xianfeng Wu
    Citation: BMC Nephrology 2022 23:68
    Content type: Research Published on:

  15. Hypocomplementemic urticarial vasculitis (HUV) is a rare systemic vasculitis. We aimed to describe the kidney involvement of HUV in a multicenter national cohort with an extended follow-up.

    Authors: Alice Corthier, Marie Jachiet, Daniel Bertin, Aude Servais, Christelle Barbet, Adrien Bigot, Marie-Sylvie Doutre, Didier Bessis, Ancuta Bouffandeau, Olivier Moranne, Pierre-André Jarrot, Nathalie Bardin, Benjamin Terrier, Stephane Burtey, Xavier Puéchal, Laurent Daniel…
    Citation: BMC Nephrology 2022 23:67
    Content type: Research Published on:

  17. Nutcracker syndrome (NCS) is characterized by compression of the left renal vein (LRV) between the aorta and the superior mesenteric artery. While rare, NCS was reported to be accompanied by double inferior ve...

    Authors: Ayumi Omori, Kan Katayama, Ryosuke Saiki, Satoru Masui, Kei Suzuki, Yoshinori Kanii, Kayo Tsujimoto, Shiro Nakamori, Tairo Kurita, Tomohiro Murata, Takahiro Inoue and Kaoru Dohi
    Citation: BMC Nephrology 2022 23:65
    Content type: Case report Published on:

  18. Diabetic nephropathy (DN) is a type of progressive kidney disease affecting approximately 40% of patients with diabetes. Current DN diagnostic criteria predominantly rely on albuminuria and serum creatinine (s...

    Authors: Hamad Ali, Mohamed Abu-Farha, Eman Alshawaf, Sriraman Devarajan, Yousif Bahbahani, Irina Al-Khairi, Preethi Cherian, Zahra Alsairafi, Vidya Vijayan, Fahd Al-Mulla, Abdulnabi Al Attar and Jehad Abubaker
    Citation: BMC Nephrology 2022 23:64
    Content type: Research Published on:

  19. Hospitalized patients with SARS-CoV2 develop acute kidney injury (AKI) frequently, yet gaps remain in understanding why adults seem to have higher rates compared to children. Our objectives were to evaluate th...

    Authors: Erica C. Bjornstad, Gary Cutter, Pramod Guru, Shina Menon, Isabella Aldana, Scott House, Nancy M. Tofil, Catherine A. St. Hill, Yasir Tarabichi, Valerie M. Banner-Goodspeed, Amy B. Christie, Surapaneni Krishna Mohan, Devang Sanghavi, Jarrod M. Mosier, Girish Vadgaonkar, Allan J. Walkey…
    Citation: BMC Nephrology 2022 23:63
    Content type: Research Published on:

  20. To develop a reliable model to predict rapid kidney function decline (RKFD) among population at risk of cardiovascular disease.

    Authors: Qiuxia Zhang, Junyan Lu, Li Lei, Guodong Li, Hongbin Liang, Jingyi Zhang, Yun Li, Xiangqi Lu, Xinlu Zhang, Yaode Chen, Jiazhi Pan, Yejia Chen, Xinxin Lin, Xiaobo Li, Shiyu Zhou, Shengli An…
    Citation: BMC Nephrology 2022 23:62
    Content type: Research Published on:

  21. Transplant renal artery stenosis (TRAS) is the main vascular complication of kidney transplantation. For research and treatment purposes, several authors consider critical renal artery stenosis to be greater t...

    Authors: Manoela Linhares Machado Barteczko, Henry Campos Orellana, Gustavo Rocha Feitosa Santos, Attílio Galhardo, Gabriel Kanhouche, Ana Carolina Buso Faccinetto, Hélio Tedesco Júnior, José Osmar Medina Pestana, Ângelo Amato Vincenzo de Paola and Adriano Henrique Pereira Barbosa
    Citation: BMC Nephrology 2022 23:61
    Content type: Research Published on:

  22. Anemia is a common complication of chronic kidney disease (CKD) and HIV infection. The number of people living with HIV on hemodialysis (HD) is increasing. However, there is no data about anemia and related th...

    Authors: Lei Peng, Yanan He, Jiong Zhang, Daqing Hong and Guisen Li
    Citation: BMC Nephrology 2022 23:60
    Content type: Research Published on:

  23. Sodium zirconium cyclosilicate (SZC) is an effective and well-tolerated treatment for hyperkalemia in maintenance hemodialysis patients. In post-hoc analyses of the phase 3b DIALIZE study, we examined the spec...

    Authors: Steven Fishbane, Martin Ford, Masafumi Fukagawa, Kieran McCafferty, Anjay Rastogi, Bruce Spinowitz, Konstantin Staroselskiy, Konstantin Vishnevskiy, Vera Lisovskaja, Ayman Al-Shurbaji, Nicolas Guzman and Sunil Bhandari
    Citation: BMC Nephrology 2022 23:59
    Content type: Research Published on:

  24. This study aimed to identify the factors related to treatment adherence behaviors among old-age hemodialysis patients in Hamadan based on the Extended Theory of Planned Behavior (ETPB) during the covid-19 pand...

    Authors: Vida Sheikh, Majid Barati, Salman Khazaei and Hanieh Jormand
    Citation: BMC Nephrology 2022 23:58
    Content type: Research Published on:

  25. During the month of Ramadan, Muslims abstain from daytime consumption of fluids and foods, although some high-risk individuals are exempt. Because fasting's effects on the risk of acute kidney injury (AKI) hav...

    Authors: Numan A. AlAbdan, Omar A. Almohammed, Maryam S. Altukhaim, Mahfooz A. Farooqui, Mubarak I. Abdalla, Hazza Q. Al Otaibi, Norah R. Alshuraym, Shahad N. Alghusun, Lama H. Alotaibi and Abdullah A. Alsayyari
    Citation: BMC Nephrology 2022 23:54
    Content type: Research Published on:

  27. To date, a few case reports have described the association between poststreptococcal acute glomerulonephritis (PSAGN) and hemolytic anemia/thrombocytopenia, both with or without a pathology similar to that of ...

    Authors: Dan Inoue, Takashi Oda, Sachiko Iwama, Takahiko Hoshino, Mitsuya Mukae, Takashi Sakai, Aki Kojima, Takahiro Uchida, Tadasu Kojima, Kentaro Sugisaki, Tomohiro Tomiyasu, Noriko Yoshikawa and Muneharu Yamada
    Citation: BMC Nephrology 2022 23:56
    Content type: Case report Published on:

  28. COVID-19 is associated with increased morbidity and mortality in patients with chronic kidney disease (CKD) stages G4-G5, on dialysis or after kidney transplantation (kidney replacement therapy, KRT). SARS-CoV...

    Authors: P. Bouwmans, A. L. Messchendorp, J. S. Sanders, L. Hilbrands, M. E. J. Reinders, P. Vart, F. J. Bemelman, A. C. Abrahams, M. A. van den Dorpel, M. A. Ten Dam, A. P. J. de Vries, T. Rispens, M. Steenhuis, R. T. Gansevoort and M. H. Hemmelder
    Citation: BMC Nephrology 2022 23:55
    Content type: Study protocol Published on:

  29. A quarter of patients do not receive any information on the modalities of renal remplacement therapy (RRT) before its initiation. In our facility, we provide therapeutic education workshops for all RRT except ...

    Authors: Abdallah Guerraoui, Roula Galland, Flora Belkahla-Delabruyere, Odile Didier, Veronique Berger, Pierre Sauvajon, Christian Serve, Jean Charles Zuriaga, Fréderic Riquier and Agnes Caillette-Beaudoin
    Citation: BMC Nephrology 2022 23:53
    Content type: Research Published on:

  30. Albumin (ALB) levels are negatively associated with mortality in patients with sepsis. However, among sepsis patients with acute kidney injury (AKI) undergoing continuous renal replacement therapy (CRRT), ther...

    Authors: Song Sheng, Yan-Hong Zhang, Hang-Kun Ma and Ye Huang
    Citation: BMC Nephrology 2022 23:52
    Content type: Research Published on:

  31. Acute T-cell mediated rejection (aTCMR) is still an issue in kidney transplantation, for it is associated with chronic rejection, graft loss, and overall worse outcomes. For these reasons, a standard non-invas...

    Authors: Angelica Canossi, Samuele Iesari, Quirino Lai, Simone Ciavatta, Tiziana Del Beato, Alessandra Panarese, Barbara Binda, Alessandra Tessitore, Franco Papola and Francesco Pisani
    Citation: BMC Nephrology 2022 23:51
    Content type: Research Published on:

  32. Acute kidney injury (AKI) is a common complication in patients hospitalized with COVID-19 and may require renal replacement therapy (RRT). Dipstick urinalysis is frequently obtained, but data regarding the progno...

    Authors: Meredith C. McAdams, Michael Li, Pin Xu, L. Parker Gregg, Jiten Patel, Duwayne L. Willett, Ferdinand Velasco, Christoph U. Lehmann and S. Susan Hedayati
    Citation: BMC Nephrology 2022 23:50
    Content type: Research Published on:

  33. The urine protein-creatinine ratio (UPCR) in a spot first-morning urine sample is used to estimate 24-h urine proteinuria (24hUP) in patients who underwent urine protein testing. UPCR cannot be directly compar...

    Authors: Fan Yang, Jing-Song Shi, Si-Wen Gong, Xiao-Dong Xu and Wei-Bo Le
    Citation: BMC Nephrology 2022 23:49
    Content type: Research Published on:

  34. Little information is available on current practice in beta-lactam dosing during continuous renal replacement therapy (CRRT). Optimized dosing is essential for improving outcomes, and there is no consensus on ...

    Authors: Elodie Matusik, Justine Lemtiri, Guillaume Wabont and Fabien Lambiotte
    Citation: BMC Nephrology 2022 23:48
    Content type: Research article Published on:

  35. The leading cause of death in end-stage kidney disease is related to cardiovascular disease. Macrophages are known to be involved in both chronic kidney disease (CKD) and heart failure, however their role in t...

    Authors: M. A. Mawhin, R. G. Bright, J. D. Fourre, E. I. Vloumidi, J. Tomlinson, A. Sardini, C. D. Pusey and K. J. Woollard
    Citation: BMC Nephrology 2022 23:47
    Content type: Research Published on:

  36. Patients receiving intermittent hemodialysis have variable times of recovery to feeling better after dialysis. QT prolongation, a precursor to clinical and subclinical cardiovascular events, may contribute to ...

    Authors: Jacqueline Watt, Jessica Fitzpatrick, Stephen M. Sozio, Bernard G. Jaar, Michelle M. Estrella, Larisa G. Tereshchenko, Jose M. Monroy-Trujillo, Michael Walsh and Rulan S. Parekh
    Citation: BMC Nephrology 2022 23:46
    Content type: Research Published on:

  37. The knowledge, skills, and confidence to manage one’s own health is termed patient activation and can be assessed using the Patient Activation Measure (PAM). This measure is increasingly recommended for use in...

    Authors: Winnie Magadi, Courtney J. Lightfoot, Katherine E. Memory, Shalini Santhakumaran, Sabine N. van der Veer, Nicola Thomas, Rachel Gair and Alice C. Smith
    Citation: BMC Nephrology 2022 23:45
    Content type: Research Published on:

  39. Cardiac valve calcification (CVC) is common in end-stage renal disease (ESRD). We investigated the effect of CVC on all-cause and cardiovascular (CV) mortality in maintenance hemodialysis (MHD) patients.

    Authors: Jiuxu Bai, Xiaoling Zhang, Aihong Zhang, Yanping Zhang, Kaiming Ren, Zhuo Ren, Chen Zhao, Qian Wang and Ning Cao
    Citation: BMC Nephrology 2022 23:43
    Content type: Research Published on:

  40. Without sufficient evidence in postoperative acute kidney injury (AKI) in critically ill patients undergoing emergency surgery, it is meaningful to explore the incidence, risk factors, and prognosis of postope...

    Authors: Linhui Hu, Lu Gao, Danqing Zhang, Yating Hou, Lin Ling He, Huidan Zhang, Yufan Liang, Jing Xu and Chunbo Chen
    Citation: BMC Nephrology 2022 23:42
    Content type: Research Published on:

  41. The kidney is the main site for the removal of chromogranin A (CgA). Previous studies have found that patients with renal impairment displayed elevated concentrations of CgA in plasma and that CgA concentratio...

    Authors: Hui Yu, Hongping Wang, Xue Su, Aili Cao, Xingmei Yao, Yunman Wang, Bingbing Zhu, Hao Wang and Ji Fang
    Citation: BMC Nephrology 2022 23:41
    Content type: Research article Published on:

  42. Pozzi protocol (methylprednisolone intravenous infusion in 1st-3rd-5th months and oral steroid for 6 months) has been thought to be the classic therapy for IgA nephropathy (IgAN) patients with proteinuria> 1.0...

    Authors: Mengjun Liang, Liping Xiong, Aihua Li, Jiafan Zhou, Yajuan Huang, Miaofang Huang, Xing Zhang, Hongrui Shi, Ning Su, Yi Wei and Zongpei Jiang
    Citation: BMC Nephrology 2022 23:40
    Content type: Research article Published on:

  43. The impact of blood pressure on neurological symptoms and risk of end-stage kidney disease (ESKD) is unknown in primary and secondary thrombotic microangiopathies (TMAs).

    Authors: Jean-Michel Halimi, Benjamin Thoreau, Florent von Tokarski, Adeline Bauvois, Juliette Gueguen, Nicolas Goin, Christelle Barbet, Sylvie Cloarec, Elodie Mérieau, Sébastien Lachot, Denis Garot, Adrien Lemaignen, Emmanuel Gyan, Franck Perrotin, Claire Pouplard, François Maillot…
    Citation: BMC Nephrology 2022 23:39
    Content type: Research Published on:

  44. Chronic kidney disease (CKD) is an independent risk factor for stroke. Stroke is also an independent risk factor for worse CKD outcomes and inflammation may contribute to this bidirectional relationship. This ...

    Authors: James Tollitt, Stuart M. Allan, Rajkumar Chinnadurai, Aghogho Odudu, Margaret Hoadley, Craig Smith and Philip A. Kalra
    Citation: BMC Nephrology 2022 23:38
    Content type: Research Published on:

  45. The aim of the study was to investigate the effect of recipient obesity on the short- and long-term outcomes of patients undergoing primary kidney transplantation (KT).

    Authors: Uwe Scheuermann, Jonas Babel, Uta-Carolin Pietsch, Antje Weimann, Orestis Lyros, Katrin Semmling, Hans-Michael Hau, Daniel Seehofer, Sebastian Rademacher and Robert Sucher
    Citation: BMC Nephrology 2022 23:37
    Content type: Research Published on:

  46. Olfactory and gustatory changes may contribute to poor appetite and food aversion in chronic kidney disease (CKD), though the prevalence of olfactory and gustatory dysfunction is not known in the CKD population.

    Authors: Api Chewcharat, Elizabeth A. Phipps, Khushboo Bhatia, Sahir Kalim, Andrew S. Allegretti, Meghan E. Sise, Teodor G. Păunescu, Rituvanthikaa Seethapathy and Sagar U. Nigwekar
    Citation: BMC Nephrology 2022 23:36
    Content type: Research Published on:

  47. Xanthine oxidoreductase (XOR) is a hydroxylase enzyme involved in the metabolism of purines. XOR activity can vary: the homodimer protein can be converted into two different isoforms XD (antioxidant) and XO (p...

    Authors: Elżbieta Cecerska-Heryć, Rafał Heryć, Grażyna Dutkiewicz, Anna Michalczyk, Bartłomiej Grygorcewicz, Natalia Serwin, Sylwia Napiontek-Balińska and Barbara Dołęgowska
    Citation: BMC Nephrology 2022 23:35
    Content type: Research article Published on:

  48. Cardiovascular disease is an important driver of the increased mortality associated with chronic kidney disease (CKD). Higher left ventricular mass (LVM) predicts increased risk of adverse cardiovascular outco...

    Authors: Kevin C. Maki, Meredith L. Wilcox, Mary R. Dicklin, Rahul Kakkar and Michael H. Davidson
    Citation: BMC Nephrology 2022 23:34
    Content type: Research Published on:

  50. To verify that the single nucleotide polymorphisms (SNP) of vitamin D receptor (VDR) may lead to genetic susceptibility to left ventricular hypertrophy (LVH), the present study was designed to study four SNPs ...

    Authors: Bingman Liu, Qingqing Yang, Liangyu Zhao, Hua Shui and Xiaoyun Si
    Citation: BMC Nephrology 2022 23:32
    Content type: Research Published on:
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BMC Nephrology

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