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  1. Content type: Research article

    Recent studies have shown associations between contrast-induced acute kidney injury (CI-AKI) and increased risk of adverse clinical outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous co...

    Authors: Yi Yang, Kaisha C. George, Ran Luo, Yichun Cheng, Weifeng Shang, Shuwang Ge and Gang Xu

    Citation: BMC Nephrology 2018 19:374

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  2. Content type: Research article

    The impact of contrast-induced acute kidney injury (CI-AKI) on patients with chronic renal disease is well-known. Remote ischemic preconditioning (RIPC) is a non-invasive method that can reduce the risk of CI-...

    Authors: Ali Ghaemian, Jamshid Yazdani, Soheil Azizi, Ali A. Farsavian, Maryam Nabati, Alireza Malekrah, Mozhdeh Dabirian, Fatemeh Espahbodi, Bahareh Mirjani, Hossein Mohsenipouya and Javad Heshmatian

    Citation: BMC Nephrology 2018 19:373

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  3. Content type: Case report

    Lupus nephritis (LN) is one of the most common manifestations of systemic lupus erythematosus (SLE) and is often the most serious organ complication and the cause of premature death of such a patient. Most of ...

    Authors: Marceli Lukaszewski, Kinga Kosiorowska, Dorota Kaminska, Marta Obremska, Oktawia Mazanowska and Magdalena Krajewska

    Citation: BMC Nephrology 2018 19:372

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  4. Content type: Research article

    This is the first qualitative study to explore patient decision-making regarding end-stage kidney disease (ESKD) treatment in sub-Saharan Africa. The study addresses an important gap in the literature concerni...

    Authors: Edward Appiah Boateng, Linda East and Catrin Evans

    Citation: BMC Nephrology 2018 19:371

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  5. Content type: Case report

    Uremic encephalopathy (UE), a toxic metabolic encephalopathy, is an uncommon complication resulting from endogenous uremic toxins in patients with severe renal failure. UE syndrome can range from mild inattent...

    Authors: Wen-Yu Gong, Shan-Shan Li, Zong-Chao Yu, Hong-Wei Wu, Liang-Hong Yin, Li-Fan Mei and Fan-Na Liu

    Citation: BMC Nephrology 2018 19:370

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  6. Content type: Research article

    The introduction of a continuous renal replacement therapy (CRRT) device into the extracorporeal membrane oxygenation (ECMO) circuit is widely used. However, excessive pressure transmitted to the CRRT device i...

    Authors: Soo Jin Na, Hee Jung Choi, Chi Ryang Chung, Yang Hyun Cho, Hye Ryoun Jang, Gee Young Suh and Kyeongman Jeon

    Citation: BMC Nephrology 2018 19:369

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  7. Content type: Research article

    Somatostatin (SST) inhibits intracellular cyclic adenosine monophosphate (cAMP) production and thus may modify cyst formation in autosomal dominant polycystic kidney disease (ADPKD). We investigated whether en...

    Authors: A. Lianne Messchendorp, Edwin M. Spithoven, Niek F. Casteleijn, Wendy A. Dam, Jacob van den Born, Wouter F. Tonnis, Carlo A. J. M. Gaillard and Esther Meijer

    Citation: BMC Nephrology 2018 19:368

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  8. Content type: Research article

    Urinary mitochondrial DNA (mtDNA) fragment level has been proposed as a biomarker of chronic kidney disease (CKD). In this study, we determine the relation between urinary mtDNA level and rate of renal functio...

    Authors: Zhongping WEI, Bonnie Ching-Ha KWAN, Kai Ming CHOW, Phyllis Mei-Shan CHENG, Cathy Choi-Wan LUK, Ka-Bik LAI, Philip Kam-Tao LI and Cheuk Chun SZETO

    Citation: BMC Nephrology 2018 19:367

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  9. Content type: Research article

    Estimation of GFR (eGFR) using formulae based on serum creatinine concentrations are commonly used to assess kidney function. Physical exercise can increase creatinine turnover and lean mass; therefore, this m...

    Authors: Kassia S. Beetham, Erin J. Howden, Nicole M. Isbel and Jeff S. Coombes

    Citation: BMC Nephrology 2018 19:366

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  10. Content type: Case report

    Bordetella pertussis infection is a known trigger of atypical hemolytic uremic syndrome (HUS). For patients suspected of having atypical HUS, prompt plasma exchange/infusion (PE/PI) or eculizumab (ECZ) treatment ...

    Authors: Ken Saida, Masao Ogura, Yuji Kano, Shingo Ishimori, Takahisa Yoshikawa, Hiroko Nagata, Mai Sato, Koichi Kamei and Kenji Ishikura

    Citation: BMC Nephrology 2018 19:365

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  11. Content type: Case report

    Distal renal tubular acidosis (dRTA) is a heterogeneous disorder characterized by normal anion gap metabolic acidosis. Autosomal recessive dRTA is usually caused by mutations occurring in ATP6V1B1 and ATP6V0A4...

    Authors: Xiangzhong Zhao, Jingru Lu, Yanxia Gao, Xiaoling Wang, Yanhua Lang and Leping Shao

    Citation: BMC Nephrology 2018 19:364

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  12. Content type: Case report

    Although the renal toxicity of Deferasirox, an oral iron chelator, has been reported to be mild, there have been reports of acute interstitial nephritis or Fanconi syndrome due to this agent. Thin basement mem...

    Authors: Keiko Oda, Kan Katayama, Akiko Tanoue, Tomohiro Murata, Yumi Hirota, Shoko Mizoguchi, Yosuke Hirabayashi, Takayasu Ito, Eiji Ishikawa, Kaoru Dohi and Masaaki Ito

    Citation: BMC Nephrology 2018 19:363

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  13. Content type: Research article

    Therapeutic plasma exchange (TPE) is an important therapy for recurrent focal segmental glomerulosclerosis (rFSGS) post kidney transplant. suPAR has been causally implicated in rFSGS, and shown to be a unique ...

    Authors: Nada Alachkar, Jing Li, Dany Matar, Vikas Vujjini, Sami Alasfar, Melissa Tracy, Jochen Reiser and Changli Wei

    Citation: BMC Nephrology 2018 19:361

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  14. Content type: Research article

    Evidence regarding the effect of psychosocial factors on hospital readmission in the setting of hemodialysis is limited. We examined whether social worker-assessed factors were associated with 30-day readmissi...

    Authors: Olufunmilola Adisa, Bernard G. Jaar, Tahsin Masud, Abyalew Sahlie, Catherine Obadina, Joshua Ang, Janice P. Lea and Laura C. Plantinga

    Citation: BMC Nephrology 2018 19:360

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  15. Content type: Research article

    Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as...

    Authors: Andrzej Jaroszyński, Anna Jaroszyńska, Tomasz Zaborowski, Anna Drelich-Zbroja, Tomasz Zapolski and Wojciech Dąbrowski

    Citation: BMC Nephrology 2018 19:359

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  16. Content type: Research article

    IgA nephropathy (IgAN) is one of the most common forms of idiopathic glomerular diseases and might lead to end-stage kidney disease. Accurate and non-invasive biomarkers for early diagnosis are required for ea...

    Authors: Zhengguang Guo, Zhao Wang, Chen Lu, Shufen Yang, Haidan Sun, Reziw, Yu Guo, Wei Sun and Hua Yue

    Citation: BMC Nephrology 2018 19:358

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  17. Content type: Research article

    Immunosuppressive treatment will predispose an idiopathic membranous nephropathy (iMN) patient to opportunistic infections. Disease severity is one of the main concerns for making the treatment decision. Urina...

    Authors: Ziyong Tang, Yue Wang, Liyuan Tao, Yanhong Guo, Yimu Zheng and Danxia Zheng

    Citation: BMC Nephrology 2018 19:357

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    The Correction to this article has been published in BMC Nephrology 2019 20:50

  18. Content type: Research article

    The hepatic circulation is involved in adaptive systemic responses to circulatory stress. However, it is vulnerable to both chronic hypervolemia and cardiac dysfunction. The influence of hemodialysis (HD) and ...

    Authors: Claire J. Grant, Trevor P. Wade, Charles A. McKenzie, Guido Filler, Christopher W. McIntyre and Shih-Han S. Huang

    Citation: BMC Nephrology 2018 19:356

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  19. Content type: Case report

    Renal thrombotic microangiopathy (TMA) is occasionally seen in biopsies with pauci-immune necrotizing crescentic glomerulonephritis (PCGN). Recent study indicated that the complement activation is more promine...

    Authors: Jianling Tao, Jonathan Lieberman, Richard A. Lafayette and Neeraja Kambham

    Citation: BMC Nephrology 2018 19:355

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  20. Content type: Research article

    Serum anti-phospholipase A2 receptor (PLA2R) antibody was correlated with disease activity of membranous nephropathy(MN). The predictive value of antibody titer changes on immunosuppressive response remains un...

    Authors: Chao Li, Hang Li, Yu-bing Wen, Xue-mei Li and Xue-wang Li

    Citation: BMC Nephrology 2018 19:354

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  21. Content type: Research article

    The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serolog...

    Authors: Yun Soo Hong, Seungho Ryu, Yoosoo Chang, Miguel Caínzos-Achirica, Min-Jung Kwon, Di Zhao, Tariq Shafi, Mariana Lazo, Roberto Pastor-Barriuso, Hocheol Shin, Juhee Cho and Eliseo Guallar

    Citation: BMC Nephrology 2018 19:353

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  22. Content type: Case report

    Baclofen is a centrally acting GABAB receptor agonist and it is used widely for the treatment of spasticity, persistent hiccups and multiple sclerosis. The renal system is the main route of excretion, thus people...

    Authors: Emad Khazneh, Alaa Shamlawi, Kamel Jebrin, Zakaria Hamdan and Osama Sawalmeh

    Citation: BMC Nephrology 2018 19:352

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  23. Content type: Research article

    Contrast enhanced ultrasonography (CEUS) assessment of kidney allografts mainly focuses on graft rejection. However, studies on delayed graft function (DGF) without acute rejection are still lacking. The aim o...

    Authors: Nordeval Cavalcante Araújo and José Hermógenes Rocco Suassuna

    Citation: BMC Nephrology 2018 19:351

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  24. Content type: Case report

    Maternally inherited diabetes and deafness (MIDD), a mitochondrial genetic disorder, typically affects the kidneys and results in end-stage renal disease. Early diagnosis of MIDD is challenging when renal mani...

    Authors: Keiji Sugai, Hiroyuki Ueda, Keita Morimoto, Mai Tanaka, Daisuke Takahashi, Akio Nakashima, Junichiro Kato, Hiroshi Takahashi, Yutaka Yamaguchi, Tetsuya Kawamura, Kazushige Hanaoka, Yoichi Miyazaki and Takashi Yokoo

    Citation: BMC Nephrology 2018 19:350

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  25. Content type: Study protocol

    Nephrolithiasis is a global healthcare problem with a current lifetime risk of 18.8% in men and 9.4% in women. Given the high cost of medical treatments and surgical interventions as well as the morbidity rela...

    Authors: Nasser A. Dhayat, Nicolas Faller, Olivier Bonny, Nilufar Mohebbi, Alexander Ritter, Lisa Pellegrini, Giulia Bedino, Carlo Schönholzer, Reto M. Venzin, Carina Hüsler, Irene Koneth, Rosaria Del Giorno, Luca Gabutti, Patrizia Amico, Michael Mayr, Urs Odermatt…

    Citation: BMC Nephrology 2018 19:349

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  26. Content type: Case report

    Post-transplant diabetes mellitus (PTDM) is an emerging problem in kidney transplantation, representing an important risk factor for kidney function loss. Diabetic nephropathy (DN) occurrence in transplanted k...

    Authors: Marilena Gregorini, Vincenzo Sepe, Francesca Eleonora Pattonieri, Anna Allesina and Teresa Rampino

    Citation: BMC Nephrology 2018 19:348

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  27. Content type: Research article

    Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the ...

    Authors: Antonio Mirijello, Francesca Viazzi, Paola Fioretto, Carlo Giorda, Antonio Ceriello, Giuspina T. Russo, Pietro Guida, Roberto Pontremoli and Salvatore De Cosmo

    Citation: BMC Nephrology 2018 19:347

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  28. Content type: Research article

    The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in c...

    Authors: Julius E. Kieswich, Jianmin Chen, Samira Alliouachene, Paul W. Caton, Kieran McCafferty, Christoph Thiemermann and Muhammad M. Yaqoob

    Citation: BMC Nephrology 2018 19:346

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  29. Content type: Research article

    Chronic Kidney Disease (CKD), the worldwide Public Health problem, is also one of the rising non-communicable diseases in low and middle-income countries. Its early detection and treatment using readily availa...

    Authors: Tamiru Adugna, Hailu Merga and Esayas Kebede Gudina

    Citation: BMC Nephrology 2018 19:345

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  30. Content type: Research article

    Acute kidney injury (AKI) is an underestimated, yet important, risk factor for the development of chronic kidney disease (CKD). Persistence of inflammation after a renal ischemic injury has been observed, both...

    Authors: Lies Moonen, Hilde Geryl, Patrick C. D’Haese and Benjamin A. Vervaet

    Citation: BMC Nephrology 2018 19:343

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  31. Content type: Research article

    Like most of the sub-Saharan countries, Tanzania faces significant increase in the number of patients diagnosed with an end-stage renal disease (ESRD) among which only a few manage to receive chronic haemodial...

    Authors: Godwin Pancras, Judith Shayo and Amani Anaeli

    Citation: BMC Nephrology 2018 19:342

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  32. Content type: Case report

    Peritoneal dialysis (PD)-associated infection caused by Mycobacterium spp. is rare. Mycobacterium abscessus is one of the most resistant acid-fast bacteria, and treatment is also the most difficult and refractory...

    Authors: Ryuichi Yoshimura, Miharu Kawanishi, Shungo Fujii, Aska Yamauchi, Kentaro Takase, Kaori Yoshikane, Masahiro Egawa, Hiroaki Shiina and Takafumi Ito

    Citation: BMC Nephrology 2018 19:341

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  33. Content type: Research article

    Patient experience in hemodialysis (HD) is measured twice yearly in all in-center HD patients in the United States using the In-Center Hemodialysis Consumer Assessment of Healthcare Providers and Systems (ICH ...

    Authors: Taimur Dad, Hocine Tighiouart, Eduardo Lacson Jr, Klemens B. Meyer, Daniel E. Weiner and Michelle M. Richardson

    Citation: BMC Nephrology 2018 19:340

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  34. Content type: Research article

    To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of ma...

    Authors: Danielle Marie Muscat, Roshana Kanagaratnam, Heather L. Shepherd, Kamal Sud, Kirsten McCaffery and Angela Webster

    Citation: BMC Nephrology 2018 19:339

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  35. Content type: Case report

    Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins r...

    Authors: Shun Manabe, Chihiro Iwasaki, Michiyasu Hatano, Fuyuki Kametani, Masahide Yazaki, Kosaku Nitta and Michio Nagata

    Citation: BMC Nephrology 2018 19:337

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  36. Content type: Research article

    There is a need for a large, contemporary, multi-centre series of measured glomerular filtration rates (mGFR) from healthy individuals to determine age- and gender-specific reference ranges for GFR. We aimed t...

    Authors: Anthony Fenton, Emma Montgomery, Peter Nightingale, A. Michael Peters, Neil Sheerin, A. Caroline Wroe and Graham W. Lipkin

    Citation: BMC Nephrology 2018 19:336

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  37. Content type: Research article

    Focal segmental glomerulosclerosis (FSGS) is the most common glomerular etiology of end-stage kidney disease (ESKD). Increasing evidence has indicated the reparative potential of mesenchymal stem cells (MSCs) ...

    Authors: Ru-chun Yang, Xiao-ling Zhu, Jun Wang, Feng Wan, Hua-qin Zhang, Yi Lin, Xuan-li Tang and Bin Zhu

    Citation: BMC Nephrology 2018 19:335

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  38. Content type: Research article

    IgA vasculitis (IgAV, formerly Henoch-Schönlein purpura) is a type of systemic vasculitis. This study aimed to explore the clinicopathological features, treatment and renal outcomes of adult IgAV-related nephr...

    Authors: Xiao Huang, Jing Wu, Xiao-mei Wu, Ya-xin Hao, Cai-hong Zeng, Zhi-hong Liu and Zheng Tang

    Citation: BMC Nephrology 2018 19:334

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  39. Content type: Research article

    Kidney diseases have emerged as significant cause of morbidity and mortality in HIV subject on antiretroviral therapy (ART). In Ghana, routine follow up of HIV positive clients is by estimation of serum creati...

    Authors: Dorcas Obiri-Yeboah, Yaw Asante Awuku, Wonderful Alofa, Alice Charwudzi, Ebenezer Aniakwa-Bonsu, Evans Obboh and Paul Nsiah

    Citation: BMC Nephrology 2018 19:333

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  40. Content type: Research article

    The goal of this study was to identify predictors for development of Pneumocystis jirovecii pneumonia (PJP) in kidney and simultaneous kidney and pancreas transplant recipients in the present era of universal pri...

    Authors: Neetika Garg, Margaret Jorgenson, Jillian Descourouez, Christopher M. Saddler, Sandesh Parajuli, Brad C. Astor, Arjang Djamali and Didier Mandelbrot

    Citation: BMC Nephrology 2018 19:332

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  41. Content type: Research article

    Human immunodeficiency virus (HIV) is associated with diverse glomerular diseases. Characteristics of minimal change nephrotic syndrome (MCNS) in this setting have been little studied, and the specific feature...

    Authors: Romain ARRESTIER, Anne-Pascale SATIE, Shao-yu ZHANG, Emmanuelle PLAISIER, Corinne ISNARD-BAGNIS, Philippe GATAULT, Quentin RAIMBOURG, David BUOB, Flavia VOCILA, Anne-Elisabeth HENG, Helene FRANCOIS, Anissa MOKTEFI, Guillaume CANAUD, Marie MATIGNON, Nathalie DEJUCQ-RAINSFORD, Isabelle BROCHERIOU…

    Citation: BMC Nephrology 2018 19:331

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  42. Content type: Case report

    IgG4-related disease (IgG4-RD) is a newly recognized fibroinflammatory condition. The kidney is one of the organs commonly affected by IgG4-RD. Tubulointerstitial nephritis (TIN) is the main feature, and membr...

    Authors: Atsushi Kitazawa, Ryo Koda, Atsunori Yoshino, Yoshihiko Ueda and Tetsuro Takeda

    Citation: BMC Nephrology 2018 19:330

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  43. Content type: Research article

    In a previous study we showed that troponin I (TnI) > 0.42 ng/mL predicted the need of dialysis in a group of 29 septic patients admitted to the intensive care unit (ICU). We aimed to confirm such finding in a...

    Authors: Daniel de Almeida Thiengo, Jorge P. Strogoff-de-Matos, Jocemir Ronaldo Lugon and Miguel Luis Graciano

    Citation: BMC Nephrology 2018 19:329

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  44. Content type: Research article

    The Oxford classification of IgA nephropathy (IgAN) defines histologic criteria (MEST-C) that provide prognostic information based on the kidney biopsy. There are few data on the predictive impact of this clas...

    Authors: Judith Isabel Schimpf, Till Klein, Christina Fitzner, Frank Eitner, Stefan Porubsky, Ralf-Dieter Hilgers, Jürgen Floege, Hermann-Josef Groene and Thomas Rauen

    Citation: BMC Nephrology 2018 19:328

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  45. Content type: Research article

    The CKD-associated decline in soluble α-Klotho (α-Klotho) levels is considered detrimental. Some studies suggest a direct induction of α-Klotho concentrations by growth hormone (GH). In the present study, the ...

    Authors: Aaltje Y. Adema, Camiel L. M. de Roij van Zuijdewijn, Joost G. Hoenderop, Martin H. de Borst, Piet M. Ter Wee, Annemieke C. Heijboer and Marc G. Vervloet

    Citation: BMC Nephrology 2018 19:327

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  46. Content type: Research article

    Tumor necrosis factor alpha (TNF-α) is considered to play an important role in the pathogenesis in IgA nephropathy (IgAN). The correlations between serum TNF-α and disease severity in patients with IgAN remain...

    Authors: Guanhong Li, Wei Wu, Xinyao Zhang, Yuan Huang, Yubing Wen, Xuemei Li and Ruitong Gao

    Citation: BMC Nephrology 2018 19:326

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  47. Content type: Research article

    Serum fibroblast growth factor 23 (FGF-23) levels are markedly elevated in haemodialysis patients and have been linked to mortality outcomes. Small studies in health and chronic kidney disease, have demonstrat...

    Authors: Matthew J. Damasiewicz, Zhong X. Lu, Peter G. Kerr and Kevan R. Polkinghorne

    Citation: BMC Nephrology 2018 19:325

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