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  1. Hemorrhagic fever with renal syndrome (HFRS) is an acute disease caused by hantavirus infection and is clinically characterized by fever, various hemorrhagic manifestations and transient renal and hepatic dysf...

    Authors: Li Zhang, Qing-shan Ma, Yan Zhang, Bai-chao Sun and Leng-yue Zhao
    Citation: BMC Nephrology 2019 20:383
  2. Background: The pathological findings of tonsils in IgA nephropathy include the expansion of T-cell nodules around lymphoid follicles and abnormal reticulation of the crypt epithelium in contrast to chronic to...

    Authors: Takuji Enya, Tomoki Miyazawa, Kohei Miyazaki, Rina Oshima, Yuichi Morimoto, Mitsuru Okada, Tsukasa Takemura and Keisuke Sugimoto
    Citation: BMC Nephrology 2019 20:381

    The Correction to this article has been published in BMC Nephrology 2024 25:110

  3. Cancer in patients with chronic kidney disease (CKD) is an added burden to their overall morbidity and mortality. Cancer can be a cause or an effect of CKD. In CKD patients, a better understanding of cancer di...

    Authors: Rajkumar Chinnadurai, Emma Flanagan, Gordon C. Jayson and Philip A. Kalra
    Citation: BMC Nephrology 2019 20:380
  4. This guideline is written primarily for doctors and nurses working in dialysis units and related areas of medicine in the UK, and is an update of a previous version written in 2009. It aims to provide guidance...

    Authors: Damien Ashby, Natalie Borman, James Burton, Richard Corbett, Andrew Davenport, Ken Farrington, Katey Flowers, James Fotheringham, R. N. Andrea Fox, Gail Franklin, Claire Gardiner, R. N. Martin Gerrish, Sharlene Greenwood, Daljit Hothi, Abdul Khares, Pelagia Koufaki…
    Citation: BMC Nephrology 2019 20:379
  5. The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health sys...

    Authors: Francis F. Furia, Jacqueline Shoo, Paschal J. Ruggajo, Kajiru Kilonzo, Gopal Basu, Karen Yeates, Santosh Varughese, Einar Svarstad and Onesmo Kisanga
    Citation: BMC Nephrology 2019 20:378
  6. Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys. Overall, it is thought to be non-pathoge...

    Authors: Vivian W. Y. Leung, Sarah-Jeanne Pilon, Pierre O. Fiset and Shaifali Sandal
    Citation: BMC Nephrology 2019 20:376
  7. TAFRO syndrome is a systemic inflammatory disorder that manifests as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Renal dysfunction is frequently complicated wit...

    Authors: Yoshikuni Nagayama, Mizuki Yamano, Motoka Yagame, Tomoyuki Nariyama, Mikiko Takahashi, Masashi Kawamoto and Katsuyuki Matsui
    Citation: BMC Nephrology 2019 20:375
  8. Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered.

    Authors: Chun-Yuan Hsiao, Chip Gresham and Mark R. Marshall
    Citation: BMC Nephrology 2019 20:374
  9. Medication non-adherence is a risk factor for acute kidney transplant rejection. The association of non-adherence with short-term allograft loss in patients who develop acute rejection and are subsequently tre...

    Authors: Ahmed Al-Sheyyab, Laura Binari, Mohammed Shwetar, Everly Ramos, Meghan E. Kapp, Stefanie Bala, Nikita Wilson, Rachel C. Forbes, J. Harold Helderman, Khaled Abdel-Kader and Beatrice P. Concepcion
    Citation: BMC Nephrology 2019 20:373
  10. Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD) in both dialysis and nondialysis patients. In clini...

    Authors: Christine K. Bailey, Stephen Caltabiano, Alexander R. Cobitz, Chun Huang, Kelly M. Mahar and Vickas V. Patel
    Citation: BMC Nephrology 2019 20:372
  11. This study was undertaken to compare the accuracy of chronic kidney disease-epidemiology collaboration (eGFRCKD-EPI) to modification of diet in renal disease (eGFRMDRD) and the Cockcroft-Gault formulas of Creatin...

    Authors: Sandro Gelsomino, Massimo Bonacchi, Fabiana Lucà, Fabio Barili, Stefano Del Pace, Orlando Parise, Daniel M. Johnson and Michele Massimo Gulizia
    Citation: BMC Nephrology 2019 20:371
  12. Numerous studies have evaluated the prevalence and importance of mineral and bone disorders among patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, little is known about d...

    Authors: Tianye Yang, Wenji Wang, Xiao Tang, Peng Shi, Lulu Zhang, Wenyan Yu, Yingxin Xie, Daqiao Guo and Feng Ding
    Citation: BMC Nephrology 2019 20:369
  13. Acute kidney injury (AKI), which may progress to end-stage kidney disease (ESKD), is a potential complication of aortic dissection. Notably, in all reported ESKD cases secondary to aortic dissection, imaging e...

    Authors: Yoshihiro Mukaiyama, Akira Okada, Yutaro Kawakatsu, Satoshi Akuzawa, Kazuchika Suzuki, Naoyuki Ishigami and Tatsuo Yamamoto
    Citation: BMC Nephrology 2019 20:368
  14. Acute kidney injury (AKI) is a common complication in patients undergoing liver transplant (LT) and is associated with high morbidity and mortality. We aim to evaluate the pattern of urine and plasma neutrophi...

    Authors: Camila Lima, Luciana Bertocco de Paiva Haddad, Patrícia Donado Vaz de Melo, Luiz Marcelo Malbouisson, Lilian Pires Freitas do Carmo, Luiz Augusto Carneiro D’Albuquerque and Etienne Macedo
    Citation: BMC Nephrology 2019 20:367
  15. Immune Checkpoint Inhibitors (ICPIs) are promising new drugs in treatment of advanced tumours targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed cell death protein-1 (PD1) or its ligand (PDL-1)...

    Authors: Mathilde Lemoine, Baptiste Dilly, Alexandre Curie, Vivien Hébert, Charlotte Laurent, Mélanie Hanoy, Steven Grangé, Dominique Guerrot, Arnaud François and Dominique Bertrand
    Citation: BMC Nephrology 2019 20:366
  16. Kidney transplantation is considered to be the treatment of choice for people with end-stage renal disease (ESRD). However, due to the shortage of available organs and the increase in the ESRD prevalence in Eu...

    Authors: M. Lorent, Y. Foucher, K. Kerleau, S. Brouard, C. Baayen, S. Lebouter, M. Naesens, O. Bestard Matamoros, A. Åsberg and M. Giral
    Citation: BMC Nephrology 2019 20:365
  17. Chronic allograft damage (CAD) is the leading cause of long-term graft dysfunction. A noninvasive method that can diagnose CAD early and monitor its development is needed.

    Authors: Qiang Zhang, Zexing Yu, Song Zeng, Lu Liang, Yue Xu, Zijian Zhang, Hao Tang, Wenjiao Jiao, Wenrui Xue, Wei Wang, Xiaodong Zhang, Tao Jiang and Xiaopeng Hu
    Citation: BMC Nephrology 2019 20:364
  18. Patients receiving maintenance hemodialysis (HD) and peritoneal dialysis (PD) are frequently hospitalized. Reducing unplanned 30-day hospital readmissions is a key priority for improving the quality of health ...

    Authors: Yu Lin, Chao Yang, Hong Chu, Jingyi Wu, Ke Lin, Ying Shi, Haibo Wang, Guilan Kong and Luxia Zhang
    Citation: BMC Nephrology 2019 20:363
  19. Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatem...

    Authors: Hongran Moon, Ho Jun Chin, Ki Young Na, Kwon Wook Joo, Yon Su Kim, Sejoong Kim and Seung Seok Han
    Citation: BMC Nephrology 2019 20:362
  20. More than 6200 End Stage Renal Disease patients in the Netherlands are dependent on dialysis, either performed at home or in a dialysis centre. Visiting a dialysis centre three times a week is considered a lar...

    Authors: A. van Eck van der Sluijs, A. A. Bonenkamp, F. W. Dekker, A. C. Abrahams and B. C. van Jaarsveld
    Citation: BMC Nephrology 2019 20:361
  21. The diagnostic value of serum M-type phospholipase A2 receptor antibody (sPLA2R-ab) expression in patients with primary membranous nephropathy (PMN) has been established. However, the association between sPLA2...

    Authors: Yufeng Liang, Jianxin Wan, Yongping Chen and Yangbin Pan
    Citation: BMC Nephrology 2019 20:360
  22. Evidences show that around 20% of biosimilar or originator erythropoiesis-stimulating agents (ESAs) users are hyporesponsive. Controversial post-marketing data exist on the predictors of ESA hyporesponsiveness...

    Authors: Ylenia Ingrasciotta, Viviana Lacava, Ilaria Marcianò, Francesco Giorgianni, Giovanni Tripepi, Graziella D’ Arrigo, Alessandro Chinellato, Daniele Ugo Tari, Domenico Santoro and Gianluca Trifirò
    Citation: BMC Nephrology 2019 20:359
  23. Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional pro...

    Authors: Ruifang Xiong, Xiangxue Lu, Jinghong Song, Han Li and Shixiang Wang
    Citation: BMC Nephrology 2019 20:358
  24. Chronic kidney disease (CKD) is often under-recognized and poorly documented via diagnoses, but the extent of under-recognition is not well understood among Medicare beneficiaries. The current study used claim...

    Authors: Clarissa J. Diamantidis, Sarah L. Hale, Virginia Wang, Valerie A. Smith, Sarah Hudson Scholle and Matthew L. Maciejewski
    Citation: BMC Nephrology 2019 20:357
  25. Pulsatility is an important property of hemodialysis arteriovenous fistulas (AVF) and can be perceived by the fingers as a gradual decrease in strength downstream from the anastomosis along the main trunk of t...

    Authors: Matt Chiung-Yu Chen, Mei-Jui Weng, Misoso Yi-Wen Wu, Yi-Chun Liu and Wen-Che Chi
    Citation: BMC Nephrology 2019 20:356
  26. Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical mani...

    Authors: Riccardo Magistroni, Alessandra Mangolini, Sonia Guzzo, Francesca Testa, Mario R. Rapanà, Renzo Mignani, Giorgia Russo, Francesco di Virgilio and Gianluca Aguiari
    Citation: BMC Nephrology 2019 20:355
  27. Although immunoglobulin A nephropathy (IgAN) is associated with an increased risk of renal allograft failure, evidences for its treatment, including renin-angiotensin-aldosterone system blockade (RAASB) usage,...

    Authors: Sehoon Park, Chung Hee Baek, Heounjeong Go, Young Hoon Kim, Sang–il Min, Jongwon Ha, Yong Chul Kim, Jung Pyo Lee, Yon Su Kim, Kyung Chul Moon, Su-Kil Park and Hajeong Lee
    Citation: BMC Nephrology 2019 20:354
  28. 17q12 deletion syndrome encompasses a broad constellation of clinical phenotypes, including renal magnesium wasting, maturity-onset diabetes of the young (MODY), renal cysts, genitourinary malformations, and n...

    Authors: Howard J. Li, Catherine Groden, Melanie P. Hoenig, Evan C. Ray, Carlos R. Ferreira, Willam Gahl and Danica Novacic
    Citation: BMC Nephrology 2019 20:353
  29. Tacrolimus (TAC) is effective in treating membranous nephropathy (MN); however relapses are frequent after treatment cessation. We conducted a randomised controlled trial to examine whether the addition of myc...

    Authors: Aikaterini Nikolopoulou, Marie Condon, Tabitha Turner-Stokes, H. Terence Cook, Neill Duncan, Jack W. Galliford, Jeremy B. Levy, Liz Lightstone, Charles D. Pusey, Candice Roufosse, Thomas D. Cairns and Megan E. Griffith
    Citation: BMC Nephrology 2019 20:352
  30. Spironolactone can improve endothelial dysfunction in the setting of heart failure and diabetes models. However, its beneficial effect in the cardiovascular system is not clear in the setting of non-diabetic r...

    Authors: Chun-Cheng Wang, An-Sheng Lee, Shu-Hui Liu, Kuan-Cheng Chang, Ming-Yi Shen and Chiz-Tzung Chang
    Citation: BMC Nephrology 2019 20:351
  31. Lupus nephritis (LN) is an inflammation of the kidneys and is a major cause of mortality in systemic lupus erythaematosus (SLE) patients. In addition, Th17/Treg balance is one of the most important factors tha...

    Authors: Dongdong Fu, Soulixay Senouthai, Junjie Wang and Yanwu You
    Citation: BMC Nephrology 2019 20:350
  32. High blood pressure is the most significant risk factor for the development and progression of chronic kidney disease (CKD). Lowering blood pressure is a goal to prevent CKD progression. This study of adults w...

    Authors: Jianzhen Zhang, Helen G. Healy, Sree Krishna Venuthurupalli, Ken-Soon Tan, Zaimin Wang, Anne Cameron and Wendy E. Hoy
    Citation: BMC Nephrology 2019 20:348
  33. Intradialytic blood pressure (BP) measurement is currently the main parameter used for monitoring hemodynamics during hemodialysis (HD). Since BP is dependent on cardiac output and total peripheral resistance,...

    Authors: Keren Doenyas-Barak, Marcia H. F. G. de Abreu, Lucas E. Borges, Helcio A. Tavares Filho, Feng Yunlin, Zou Yurong, Nathan W. Levin, Allen M. Kaufman, Shay Efrati, David Pereg, Ilya Litovchik, Shmuel Fuchs and Sa’ar Minha
    Citation: BMC Nephrology 2019 20:347
  34. Kidney transplantation is the optimal treatment in end stage renal disease but the allograft survival is still hampered by immune reactions against the allograft. This process is driven by the recognition of a...

    Authors: Constantin Aschauer, Kira Jelencsics, Karin Hu, Andreas Heinzel, Julia Vetter, Thomas Fraunhofer, Susanne Schaller, Stephan Winkler, Lisabeth Pimenov, Guido A. Gualdoni, Michael Eder, Alexander Kainz, Heinz Regele, Roman Reindl-Schwaighofer and Rainer Oberbauer
    Citation: BMC Nephrology 2019 20:346
  35. Patients with end-stage renal disease have a higher risk of death from cardiovascular events, which can be mainly attributed to coronary artery calcification (CAC). Wnt signaling is involved in vascular develo...

    Authors: Tzung-Yo Ho, Nai-Ching Chen, Chih-Yang Hsu, Chien-Wei Huang, Po-Tsang Lee, Kang-Ju Chou, Hua-Chang Fang and Chien-Liang Chen
    Citation: BMC Nephrology 2019 20:345
  36. Patient-reported outcome measures (PROMs) are becoming increasingly important in healthcare. In nephrology, there is no agreement on which chronic kidney disease (CKD) symptom questionnaire to use. Therefore, ...

    Authors: Esmee M. van der Willik, Yvette Meuleman, Karen Prantl, Giel van Rijn, Willem Jan W. Bos, Frans J. van Ittersum, Hans A. J. Bart, Marc H. Hemmelder and Friedo W. Dekker
    Citation: BMC Nephrology 2019 20:344
  37. Neighborhood racial mix is associated with dialysis facility performance metrics and mortality outcomes in patients on hemodialysis. We explored the association of neighborhood racial mix with emergency depart...

    Authors: Ladan Golestaneh, Atessa Farzami, Chikeluba Madu, Tanya Johns, Michal L. Melamed and Keith C. Norris
    Citation: BMC Nephrology 2019 20:343
  38. Approximately 4–6% of incident end stage renal disease (ESRD) patients in the U.S. recover enough kidney function to discontinue dialysis but there is considerable geographic variation. We undertook this study...

    Authors: Zijin Chen, Benjamin J. Lee, Charles E. McCulloch, Nilka Ríos Burrows, Michael Heung, Raymond K. Hsu, Meda E. Pavkov, Neil R. Powe, Rajiv Saran, Vahakn Shahinian and Chi-yuan Hsu
    Citation: BMC Nephrology 2019 20:342
  39. Kidney transplantation is the treatment of choice in end-stage renal disease due to Alport syndrome (AS). However, the chances of finding an adequate living-related donor in AS are much worse compared to non-h...

    Authors: Friederike Petzold, Anette Bachmann, Carsten Bergmann, Udo Helmchen and Jan Halbritter
    Citation: BMC Nephrology 2019 20:340
  40. Microscopic polyangiitis (MPA) is a systemic autoimmune disease, and renal involvement is frequently present in MPA. MPA patients with renal involvement may have a worse prognosis. In this study, we aimed to e...

    Authors: Jia Shi, Qing Shen, Xue-Mei Chen and Xiao-Gang Du
    Citation: BMC Nephrology 2019 20:339
  41. Sleep disturbance is common among chronic haemodialysis patients, which leads to poor quality of life, in addition to increased instances of morbidity and mortality. Hypervolemia has been linked to sleep probl...

    Authors: Sethanant Sethakarun, Sutachard Bijaphala, Chagriya Kitiyakara, Sarinya Boongird, Pariya Phanachet, Sirimon Reutrakul, Kwanchai Pirojsakul and Arkom Nongnuch
    Citation: BMC Nephrology 2019 20:211
  42. Chronic Kidney Disease (CKD) of uncertain origin (CKDu) has affected North Central Province (Anuradhapura and Polonnaruwa districts) of Sri Lanka. The cause is still unknown. The objective of this study was to...

    Authors: Asanga Venura Ranasinghe, Gardiye Weligamage Gamini Priyantha Kumara, Ranamuka Henayage Karunarathna, Ambepitiyawaduge Pubudu De Silva, Korale Gedara Dilini Sachintani, Jayaprakara Mudiyanselage Chathurika Nayani Gunawardena, Sembu Kuttige Champika Ruwan Kumari, Mohamed Shali Fathima Sarjana, Janaka Sri Chandraguptha and Mannikawadumesthri Vipula Chandu De Silva
    Citation: BMC Nephrology 2019 20:338
  43. Autosomal dominant polycystic kidney disease (ADPKD) may manifest non-nephrotic range proteinuria, but is rarely complicated with nephrotic syndrome. Limited number of reports describe the histology of ADPKD w...

    Authors: Yasuhiro Oda, Naoki Sawa, Eiko Hasegawa, Hiroki Mizuno, Masahiro Kawada, Akinari Sekine, Rikako Hiramatsu, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Kenmei Takaichi, Keiichi Kinowaki, Kenichi Ohashi, Takeshi Fujii and Yoshifumi Ubara
    Citation: BMC Nephrology 2019 20:337
  44. The nature of immunoglobulin M (IgM) nephropathy has been controversial for a long time, but it is now considered an independent disease like immunoglobulin A nephropathy. IgM nephropathy has been known to hav...

    Authors: Kyoung Sook Park, Ea Wha Kang and Jeong Hae Kie
    Citation: BMC Nephrology 2019 20:335
  45. The value of ANCA positivity in the setting of systemic lupus erythematous and their pathogenicity remains uncertain.

    Authors: Marie Lemerle, Anne-Sophie Garnier, Anne Croue, Alain Chevailler, Jean-Paul Saint-André, Jean-François Subra, Jean-François Augusto and Julien Demiselle
    Citation: BMC Nephrology 2019 20:334

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