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  1. According to dietary recommendations, reduction of sodium intake has potential to reduce Chronic Kidney Disease (CKD) risk; however the role of dietary potassium and the sodium -to- potassium ratio in the deve...

    Authors: Samuel L. Swift, Yelena Drexler, Daniela Sotres-Alvarez, Leopoldo Raij, Maria M. Llabre, Neil Schneiderman, Linda Van Horn, James P. Lash, Yasmin Mossavar-Rahmani and Tali Elfassy
    Citation: BMC Nephrology 2022 23:133
    Content type: Research Published on:

  2. In the light of recent years, an increase in the number of life-threatening infections due to various fungi has been observed, especially in tertiary care centres. With Amphotericin B labelled as the first cho...

    Authors: Yusri Abdel-Hafez, Hani Siaj, Mohammad Janajri, Yazan Abu-Baker, Zaher Nazzal, Zakaria Hamdan, Rabee Adwan, Banan M. Aiesh and Ahmad I. Anaya
    Citation: BMC Nephrology 2022 23:132
    Content type: Research Published on:

  3. Up to 60% of pediatric renal transplant recipients with end-stage renal disease due to primary focal and segmental glomerulosclerosis (FSGS) may develop recurrent disease. Such recurrence is associated with po...

    Authors: Jaime M. Restrepo, Laura Torres-Canchala, Hernando Londoño, Eliana Manzi and Michael J. G. Somers
    Citation: BMC Nephrology 2022 23:131
    Content type: Research Published on:

  4. Different dialysis treatments may affect the composition and structure of the intestinal flora of dialysis-treated chronic kidney disease (CKD) patients. This study aimed to analyze the correlations between th...

    Authors: Jianguang Hu, Xiaoshi Zhong, Yan Liu, Jing Yan, Daoyuan Zhou, Danping Qin, Xiao Xiao, Yuanyuan Zheng, Luona Wen, Rongshao Tan, Pan Liang and Yun Liu
    Citation: BMC Nephrology 2022 23:130
    Content type: Research Published on:

  5. Aortic valve stenosis (AS) has a high prevalence and poor prognosis in patients who receive maintenance dialysis. However, few large-scale observational studies in Japan have investigated patients with AS who ...

    Authors: Yuji Sasakawa, Naoki Okamoto, Maya Fujii, Jyoichiro Kato, Yukio Yuzawa and Daijo Inaguma
    Citation: BMC Nephrology 2022 23:129
    Content type: Research Published on:

  7. Published literatures on repeat renal biopsy of AL amyloidosis have basically reached a consensus that amyloid material deposit does not disappear or diminish after satisfactory hematologic response, regardles...

    Authors: Ping Zhang, Xiuling Chen, Yurong Zou, Wei Wang and Yunlin Feng
    Citation: BMC Nephrology 2022 23:127
    Content type: Case report Published on:

  8. Depressive symptoms, fatigue, and poor sleep quality are associated with renal function deterioration in patients with nondialysis chronic kidney disease (CKD-ND). This study was designed to examine whether fa...

    Authors: Ya-Fang Ho, Pei-Ti Hsu and Kai-Ling Yang
    Citation: BMC Nephrology 2022 23:126
    Content type: Research Published on:

  10. Nuclear receptor-binding SET domain protein 2 (NSD2) is a histone methyltransferase that has been demonstrated to regulate insulin secretion and glucose concentration. This study focused on the role of NSD2 in...

    Authors: Weiming Tang, Yilin Zhao, Hui Zhang, Ying Peng and Zhilian Rui
    Citation: BMC Nephrology 2022 23:124
    Content type: Research Published on:

  11. Cardiovascular (CV) disease is the leading cause of mortality in patients with end-stage kidney disease (ESKD). The aim of the present study was to determine whether Proprotein Convertase Subtilisin/Kexin type...

    Authors: François-Pantaléon Musungayi Kajingulu, François Bompeka Lepira, Aliocha Natuhoyila Nkodila, Jean-Robert Rissassy Makulo, Vieux Momeme Mokoli, Pepe Mfutu Ekulu, Justine Busanga Bukabau, Yannick Mayamba Nlandu, Augustin Luzayadio Longo, Nazaire Mangani Nseka, Laura Labriola and Ernest Kiswaya Sumaili
    Citation: BMC Nephrology 2022 23:123
    Content type: Research Published on:

  12. Haemolytic uraemic syndrome (HUS) is a severe syndrome that causes a substantial burden for patients and their families and is the leading cause of acute kidney injury in children. However, data on the epidemi...

    Authors: Jingnan Feng, Ke Xu, Xinmiao Shi, Lu Xu, Lili Liu, Fang Wang, Xuhui Zhong, Guozhen Liu, Jinxi Wang, Pei Gao, Jie Ding, Shengfeng Wang and Siyan Zhan
    Citation: BMC Nephrology 2022 23:122
    Content type: Research Published on:

  13. Informed dialysis selection and greater home dialysis use are the two long-desired, underachieved targets of advanced chronic kidney disease (CKD) care in the US healthcare system. Observational institutional ...

    Authors: Ashutosh M. Shukla, Jennifer Hale-Gallardo, Tatiana Orozco, Ivette Freytes, Zachary Purvis, Sergio Romero and Huanguang Jia
    Citation: BMC Nephrology 2022 23:121
    Content type: Research Published on:

  14. Chronic kidney disease (CKD) affects 8 to 16% of the world’s population and is one of the top ten important drivers of increasing disease burden. Apart from genetic predisposition, lifestyle factors greatly co...

    Authors: Ting Yin, Yilong Chen, Lei Tang, Huaihong Yuan, Xiaoxi Zeng and Ping Fu
    Citation: BMC Nephrology 2022 23:120
    Content type: Research Published on:

  15. Hemodialysis (HD) treatment affects functioning, physical activity level, clinical biomarkers, and body composition. However, the association between these variables with functioning, considering International...

    Authors: Luciana M. M. Santos, Pedro Henrique S. Figueiredo, Ana C. R. Silva, Patrícia C. Campos, Gabriele T. Gonçalves, Jaqueline de Paula C Freitas, Fidelis Antônio da Silva Junior, Jousielle Márcia Santos, Frederico L. Alves, Vanessa G. B. Rodrigues, Emílio Henrique B. Maciel, Maria Cecília S. M. Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Vanessa P. Lima…
    Citation: BMC Nephrology 2022 23:119
    Content type: Research article Published on:

  16. IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated...

    Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Hans-Peter Marti, Frode Berven and Bjørn Egil Vikse
    Citation: BMC Nephrology 2022 23:118
    Content type: Research Published on:

  17. Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstr...

    Authors: Yingquan Xiong, Denis Delic, Shufei Zeng, Xin Chen, Chang Chu, Ahmed A. Hasan, Bernhard K. Krämer, Thomas Klein, Lianghong Yin and Berthold Hocher
    Citation: BMC Nephrology 2022 23:117
    Content type: Research Published on:

  19. Studies have revealed that patients with chronic kidney disease (CKD) have dietary patterns different from those of the general population. However, no studies have compared the dietary patterns of between pat...

    Authors: Hsin-I. Lin, Hui-Ming Chen, Chien-Chin Hsu, Hung-Jung Lin, Jhi-Joung Wang, Shih-Feng Weng, Yuan Kao and Chien-Cheng Huang
    Citation: BMC Nephrology 2022 23:115
    Content type: Research Published on:

  20. Maintaining a low-protein diet (LPD) is important for patients with chronic kidney disease (CKD) to delay renal degradation and alleviate clinical symptoms. For most patients with CKD, it is difficult to maint...

    Authors: Junbao Shi, Yue Wang, Song Wang, Xinhong Lu, Xinxin Chen and Danxia Zheng
    Citation: BMC Nephrology 2022 23:114
    Content type: Research Published on:

  22. Regorafenib belongs to a sub-group of small-molecule multi-targeted tyrosine kinase inhibitors(TKIs). In various studies with respect to the side-effect of regorafenib, drug-associated proteinuria standardly q...

    Authors: Qinghua Yin, Na Guo, Xueli Zhou, Huan Xu, Song Lei, Ping Fu and Hui Zhong
    Citation: BMC Nephrology 2022 23:112
    Content type: Case report Published on:

  23. Through regulation of signaling pathways, microRNAs (miRNAs) can be involved in sepsis and associated organ dysfunction. The aims of this study were to track the 7-day time course of blood miRNAs in patients w...

    Authors: Nadezda Petejova, Arnost Martinek, Josef Zadrazil, Viktor Klementa, Lenka Pribylova, Radim Bris, Marcela Kanova, Radka Sigutova, Ivana Kacirova, Zdenek Svagera, Eva Bace and David Stejskal
    Citation: BMC Nephrology 2022 23:111
    Content type: Research Published on:

  24. Children with sickle cell anemia (SCA) are at increased risk of acute kidney injury (AKI) that may lead to death or chronic kidney disease. This study evaluated AKI prevalence and risk factors in children with...

    Authors: Anthony Batte, Sahit Menon, John Ssenkusu, Sarah Kiguli, Robert Kalyesubula, Joseph Lubega, Edrisa Ibrahim Mutebi, Robert O. Opoka, Chandy C. John, Michelle C. Starr and Andrea L. Conroy
    Citation: BMC Nephrology 2022 23:110
    Content type: Research Published on:

  25. We evaluated restenosis rates at the cephalic arch after percutaneous angioplasty and stenting procedures in patients with brachial artery to cephalic vein arteriovenous fistula (BCAVF) hemodialysis access.

    Authors: Rishi N. Razdan, Melvin Rosenblatt, Yue Jiao, Nancy McLaughlin, Len A. Usvyat, Murat Sor and John W. Larkin
    Citation: BMC Nephrology 2022 23:109
    Content type: Research Published on:

  26. After kidney transplantation neurologic manifestations may develop, including Parkinson’s disease (PD). An enlarged substantia nigra (SN) by transcranial sonography has been recognized as a marker of PD.

    Authors: Nordeval Cavalcante Araújo, José Hermógenes Rocco Suassuna and Rita de Cássia Leite Fernandes
    Citation: BMC Nephrology 2022 23:108
    Content type: Research Published on:

  28. As hemodialysis is administered with the patient lying down, the distribution of body fluid is stable in the lying position, which is why this position is recommended for bioimpedance analysis (BIA). Although ...

    Authors: Gwangho Choi, Ho Joong Yoon, Young Jin Song, Hae Min Jeong, Jae Eon Gu, Miyeun Han, Seok Hyung Kim, Jong-Woo Yoon and Hyunsuk Kim
    Citation: BMC Nephrology 2022 23:106
    Content type: Research Published on:

  29. Renal fibrosis is a common outcome of various renal damage, including diabetic nephropathy (DN), the leading cause of end-stage renal disease. Currently, there are no effective therapies for renal fibrosis. Th...

    Authors: Liangxiang Xiao, Anqun Chen, Qing Gao, Bo Xu, Xiaodan Guo and Tianjun Guan
    Citation: BMC Nephrology 2022 23:105
    Content type: Research Published on:

  30. Patients with end-stage kidney disease (ESKD) face higher risks of life-threatening events including cardiovascular disease. Various risk factors are identified as agents influencing the life prognosis of ESKD...

    Authors: Takashi Tawara-Iida, Joichi Usui, Itaru Ebihara, Takashi Ishizu, Masaki Kobayashi, Yoshitaka Maeda, Hiroaki Kobayashi, Tokuro Kobayashi, Atsushi Ueda, Makoto Tsuchida, Shinichiro Sakai and Kunihiro Yamagata
    Citation: BMC Nephrology 2022 23:104
    Content type: Research Published on:

  31. Immunotactoid Glomerulopathy (ITG) is an exceedingly rare type of glomerulopathy characterised by distinctive electron microscopic features. ITG has been linked to lymphoproliferative or autoimmune disorders. ...

    Authors: Mohamed Wael Mohamed, Mariam Al-Hammadi, Ali Mohammad Hussein, Daher Alarab, Hisham Ahmad Albreak, Mohammad Fahim Tungekar and Balaji Dandi
    Citation: BMC Nephrology 2022 23:103
    Content type: Case report Published on:

  32. Early fluid management is considered a key element affecting mortality in critically ill patients requiring continuous renal replacement therapy (CRRT). Most studies have primarily focused on patients with int...

    Authors: Kyun Young Kim, Jung-Hwa Ryu, Duk-Hee Kang, Seung-Jung Kim, Kyu Bok Choi and Shina Lee
    Citation: BMC Nephrology 2022 23:102
    Content type: Research Published on:

  33. Infections remain a major cause of morbidity and mortality in kidney transplant (KT) recipients. This study aimed to investigate the preservation fluid (PF) samples from deceased donors and report the impacts ...

    Authors: Fei Zhang, Jinbiao Zhong, Handong Ding and Guiyi Liao
    Citation: BMC Nephrology 2022 23:101
    Content type: Research Published on:

  34. Treatment with erythropoietin is well established for anemia in chronic kidney disease patients but not well studied in acute kidney injury.

    Authors: Mabel Aoun, Ghassan Sleilaty, Celine Boueri, Eliane Younes, Kim Gabriel, Reine-Marie Kahwaji, Najla Hilal, Jenny Hawi, Rita Araman, Dania Chelala and Chadia Beaini
    Citation: BMC Nephrology 2022 23:100
    Content type: Research Published on:

  35. The aims of this study were to investigate the prevalence and the influence factors of gastrointestinal symptoms, and its association with the quality of life (QOL) in peritoneal dialysis (PD) patients.

    Authors: Chunyan Yi, Xin Wang, Hongjian Ye, Jianxiong Lin and Xiao Yang
    Citation: BMC Nephrology 2022 23:99
    Content type: Research Published on:

  36. Chronic stimulation of the mineralocorticoid receptor has been suggested as one of the potential causes of cardiovascular events and death in patients with end-stage renal disease. This observational cohort st...

    Authors: Juhee Kim, Kyu-sang Yun, Ajin Cho, Do Hyoung Kim, Young-Ki Lee, Myung-Jin Choi, Seok-hyung Kim, Hyunsuk Kim, Jong-Woo Yoon and Hayne C. Park
    Citation: BMC Nephrology 2022 23:98
    Content type: Research Published on:

  37. Long-term kidney transplant survival at the population level is consistently favorable, but this survival varies widely at an individual level due to both recipient and donor factors. The distinct contribution...

    Authors: Atit A. Dharia, Michael Huang, Michelle M. Nash, Niki Dacouris, Jeffrey S. Zaltzman and G. V. Ramesh Prasad
    Citation: BMC Nephrology 2022 23:97
    Content type: Research Published on:

  39. Excessive salt intake is associated with the deterioration of chronic kidney disease (CKD). Aldosterone is also known as an independent risk factor for kidney injury. Dietary sodium intake acts as a main stimu...

    Authors: Hongmei Zhang, Bin Zhu, Liyang Chang, Xingxing Ye, Rongrong Tian, Luchen He, Dongrong Yu, Hongyu Chen and Yongjun Wang
    Citation: BMC Nephrology 2022 23:95
    Content type: Research article Published on:

  40. Acute Kidney Injury (AKI) is a frequent and serious postoperative complication in trauma or critically ill patients in the intensive care unit. We aimed to estimate the risk of AKI following major emergency ab...

    Authors: Theis B. Mikkelsen, Anders Schack, Jakob O. Oreskov, Ismail Gögenur, Jakob Burcharth and Sarah Ekeloef
    Citation: BMC Nephrology 2022 23:94
    Content type: Research article Published on:

  41. Chronic kidney disease (CKD) is a major global health problem. Short-term self-management has been considered to effect some renal and psychological endpoints. However, there are currently very few studies abo...

    Authors: Wen-wei Ouyang, Hui-fen Chen, Xue-yi Xu, Xian-long Zhang, Li-zhe Fu, Fang Tang, Ze-huai Wen, Gaetano Marrone, Li-chang Liu, Jing-xia Lin, Xu-sheng Liu and Yi-fan Wu
    Citation: BMC Nephrology 2022 23:93
    Content type: Study protocol Published on:

  42. Patients receiving in-center hemodialysis experience disproportionate morbidity and incur high healthcare-related costs. Much of this cost stems from potentially avoidable hospitalizations. Peer mentorship has...

    Authors: Ladan Golestaneh, Michal Melamed, Ryung S. Kim, Jennifer St. Clair Russell, Michele Heisler, Lisandra Villalba, Taylor Perry and Kerri L. Cavanaugh
    Citation: BMC Nephrology 2022 23:92
    Content type: Study protocol Published on:

  43. Antibody-mediated rejection (AMR) was described in kidney transplant patients after viral infections, such as the cytomegalovirus. Very few cases were recently reported after severe acute respiratory syndrome ...

    Authors: Nicole Nourié, Hussein Nassereddine, Sarah Mouawad, Louaa Chebbou, Rita Ghaleb, Fatmeh Abbas and Hiba Azar
    Citation: BMC Nephrology 2022 23:91
    Content type: Case report Published on:

  44. Acute kidney injury (AKI) is a frequent and serious complication in patients with primary nephrotic syndrome (PNS). We aimed to evaluate the influencing factors of AKI in patients with PNS, to provide implicat...

    Authors: Honghua Lu, Liping Xiao, Mengqi Song, Xiaolan Liu and Fang Wang
    Citation: BMC Nephrology 2022 23:90
    Content type: Research Published on:

  45. Diabetic nephropathy (DN) is one of the most common and serious complications of diabetes, which can lead to renal failure and fatality. miRNAs are an important class of endogenous non-coding RNAs implicated i...

    Authors: Langen Zhuang, Xiaoxu Ge, Xiaolei Hu, Qingqing Yang, Xiaoyan Pei and Guoxi Jin
    Citation: BMC Nephrology 2022 23:89
    Content type: Research Published on:

  46. Self-management of chronic kidney disease (CKD) is one of the keys in improving CKD outcomes and quality of life. There has been an increased use of online health communities to share the experiences of those ...

    Authors: Yan Du, Brittany Dennis, Valerie Ramirez, Chengdong Li, Jing Wang and Christiane L Meireles
    Citation: BMC Nephrology 2022 23:88
    Content type: Research Published on:

  48. Although metabolic acidosis is known as a potential complication of chronic kidney disease (CKD), there is limited information concerning the association between metabolic acidosis and clinical outcomes.

    Authors: Hirotaka Fukasawa, Mai Kaneko, Yuri Uchiyama, Hideo Yasuda and Ryuichi Furuya
    Citation: BMC Nephrology 2022 23:86
    Content type: Research article Published on:

  49. Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. Defect in cilia-mediated signaling activity is a crucial factor leading to cyst formation. Hence, ADPKD is reg...

    Authors: Ewa Zalewska, Sonia Kaniuka-Jakubowska, Piotr Wiśniewski, Magdalena Jankowska, Krzysztof Sworczak and Alicja Dębska-Ślizień
    Citation: BMC Nephrology 2022 23:85
    Content type: Research Published on:

  50. This study assessed the efficacy, tolerability and pharmacokinetics (PK) of lanthanum carbonate (LC) in hyperphosphatemic children and adolescents with chronic kidney disease (CKD) undergoing dialysis.

    Authors: Anna Wasilewska, Rose Ann Murray, Aimee Sundberg, Sharif Uddin, Heinrich Achenbach, Aleksey Shavkin, Tamás Szabó, Andrea Vergani and Obi Umeh
    Citation: BMC Nephrology 2022 23:84
    Content type: Research Published on:
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