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  1. The exact optimal timing of dialysis for ESKD patients remains unknown. This study systematically reviewed the available evidence with regard to the optimal initiation of maintenance dialysis in ESKD patients.

    Authors: Xiaoyan Jia, Xueqing Tang, Yunfeng Li, Dongmei Xu and Paulo Moreira
    Citation: BMC Nephrology 2023 24:162
  2. Continuous kidney replacement therapy (CKRT) is an increasingly common intervention for critically ill patients with kidney failure. Because CKRT affects body temperature, detecting infections in patients on C...

    Authors: Douglas W. Challener, Xiaolan Gao, Shahrzad Tehranian, Kianoush B. Kashani and John C. O’Horo
    Citation: BMC Nephrology 2023 24:161
  3. Non-invasive, prompt, and proper detection tools for kidney graft injuries (KGIs) are awaited to ensure graft longevity. We screened diagnostic biomarkers for KGIs following kidney transplantation using extrac...

    Authors: Hiroshi Harada, Nobuyuki Fukuzawa, Toyofumi Abe, Ryoichi Imamura, Noriyuki Masaki, Nobuhiro Fujiyama, Shigeru Sato, Shingo Hatakeyama, Kenji Nishimura, Hidefumi Kishikawa, Daiki Iwami, Kiyohiko Hotta, Masayoshi Miura, Kentaro Ide, Michio Nakamura, Akihiro Kosoku…
    Citation: BMC Nephrology 2023 24:158
  4. Epidemics of chronic kidney disease of undetermined causes (CKDu) among young male agricultural workers have been observed in many tropical regions. Western Kenya has similar climatic and occupational characte...

    Authors: Michelle H. Hathaway, Crystal L. Patil, Aloyce Odhiambo, Dickens Onyango and Samuel Dorevitch
    Citation: BMC Nephrology 2023 24:157
  5. Arteriovenous fistula (AVF) due to renal allograft biopsy is mechanical trauma resulting from the penetration of small arteries and veins by a core needle. Most AVFs are reported to resolve asymptomatically an...

    Authors: Yujiro Aoki, Takeshi Kawamura, Nobuyuki Shiraga, Takashi Yonekura, Maho Maeda, Sota Kurihara, Yoshitaka Sekine, Seiichiro Shishido and Ken Sakai
    Citation: BMC Nephrology 2023 24:156
  6. Uremic pruritus (UP) is a common and distressing symptom in end stage renal disease (ESRD) patients. Many approaches have been tested to improve UP without a clear success. We aimed to assess the effect of ser...

    Authors: Mohamed Mamdouh Elsayed, Iman Ezzat Elgohary, Heidi Hesham Said Abdelhamid and Sherif Aziz Zaki
    Citation: BMC Nephrology 2023 24:155
  7. Thrombospondin-2 (TSP-2) is a multifunctional matricellular glycoprotein correlated with glucose homeostasis, insulin sensitivity, and estimated glomerular filtration rate. Investigation of the association of ...

    Authors: Zhenzhen Lin, Didong Zhang, Xinxin Zhang, Wanxie Guo, Wenjun Wang, Yingchao Zhang, Zhen Liu, Yanxue Bi, Maolan Wu, Zhuofeng Lin and Xuemian Lu
    Citation: BMC Nephrology 2023 24:154
  8. Ubiquitin-specific proteases (USPs) are closely related to protein fate and cellular processes through various molecular signalling pathways, including DNA damage repair, p53, and transforming growth factor-β ...

    Authors: Renjie Wang, Yang Liu, Jingxian Li, Yubao Zhao, Rui An and Zhifang Ma
    Citation: BMC Nephrology 2023 24:153
  9. Recent studies have shown that donor nephrectomy can induce renal function impairment. However, few meta-analysis studies about this have proceeded. Therefore, the objective of this systematic review and meta-...

    Authors: Jun Young Park, Won Jae Yang, Seung Whan Doo, Jae Joon Park, Yong Nam Gwon, Ki Min Kim, Jae Heon Kim and Do Kyung Kim
    Citation: BMC Nephrology 2023 24:152
  10. A significant decrease in antibody titres several months after COVID-19 primary vaccination in end-stage kidney disease (ESKD) patients receiving maintenance haemodialysis has recently been reported. The wanin...

    Authors: Metalia Puspitasari, Prenali D. Sattwika, Auliana R. P. Hidayat, Wynne Wijaya, Yulia Wardhani, Umi S. Intansari, Nyoman Kertia, Bambang Purwanto and Jarir At Thobari
    Citation: BMC Nephrology 2023 24:151
  11. Proton Pump Inhibitors (PPI) are among the most commonly used drugs to treat acid-related gastrointestinal disorders in the USA. Although PPI use has been linked to acute interstitial nephritis, the side effec...

    Authors: Yue Zhang, Nasrollah Ghahramani, Hadie Razjouyan, Djibril M. Ba and Vernon M. Chinchilli
    Citation: BMC Nephrology 2023 24:150
  12. Chronic kidney disease (CKD) is a major public health concern due to its high mortality risk, high hospitalization rates and cost, and low life expectancy. Thus, CKD patients are among patient group that may b...

    Authors: Aysel Pehlivanli, Sahin Eyupoglu, Bilgen Basgut, Sehsuvar Erturk and A. Tanju Ozcelikay
    Citation: BMC Nephrology 2023 24:149
  13. The terms “renal regenerating nodule” and “nodular compensatory hypertrophy” are used in the literature to describe functioning pseudo-tumors (FPT) in the setting of an extensively scarred kidney. FPTs are usu...

    Authors: Enas Hussein Mohammed, Ahmad Kaddourah, Noor Al Khori and Mehdi Djekidel
    Citation: BMC Nephrology 2023 24:148
  14. Dimercaptosuccinic acid (DMSA) therapy is a kind of chelation therapy for patients with Wilson ‘s disease (WD). While there have been reports of side effects associated with DMSA, the development of membranous...

    Authors: Xiang Li, FengXin Hu and Gaosi Xu
    Citation: BMC Nephrology 2023 24:147
  15. The currently recommended dose of rituximab for primary membranous nephropathy is as high as that for lymphoma. However, the clinical manifestations of membranous nephropathy vary widely. Therefore, achieving ...

    Authors: Song Wang, Zhenling Deng, Yue Wang, Wenhan Bao, Sijia Zhou, Zhuan Cui and Danxia Zheng
    Citation: BMC Nephrology 2023 24:146
  16. Incidence of acute kidney injury (AKI) is known to peak in winter months. This is likely influenced by seasonality of commonly associated acute illnesses. We set out to assess seasonal mortality trends for pat...

    Authors: Esther Wong, Javeria Peracha, David Pitcher, Anna Casula, Retha Steenkamp, James F Medcalf and Dorothea Nitsch
    Citation: BMC Nephrology 2023 24:144
  17. Thrombotic thrombocytopenic purpura (TTP) is rare and severe thrombotic microangiopathy characterized by thrombocytopenia, hemolytic anemia, and renal dysfunction. In contrast, essential thrombocythemia (ET) i...

    Authors: Chunmei Qin, Dan Yin, Fang Liu and Hongyu Qiu
    Citation: BMC Nephrology 2023 24:143
  18. Total cholesterol is inversely associated with mortality in dialysis patients, which seems implausible in real-world clinical practice. May there be an optimal range of total cholesterol associated with a lowe...

    Authors: Junnan Wu, Ruifeng Yang, Xiaoyang Wang, Xiaojiang Zhan, Yueqiang Wen, Xiaoran Feng, Niansong Wang, Fenfen Peng, Guihua Jian and Xianfeng Wu
    Citation: BMC Nephrology 2023 24:142
  19. Sodium and chloride disturbances have attracted increasing attention in recent years. Many pathophysiological effects are associated with hyperchloremia, including reduction in mean arterial pressure and acute...

    Authors: Michele Luglio, Werther B. de Carvalho, Uenis Tannuri, Ana Cristina A. Tannuri, Rodrigo Hideki Matsura, Gardenia Morais França and Artur F. Delgado
    Citation: BMC Nephrology 2023 24:141
  20. Patients with COVID-19 have a high incidence of acute kidney injury (AKI), which is associated with mortality. The objective of the study was to determine the factors associated with AKI in patients with COVID...

    Authors: Kateir Contreras-Villamizar, Oscar Barbosa, Ana Cecilia Muñoz, Juan Sebastián Suárez, Camilo A. González, Diana Carolina Vargas, Martha Patricia Rodríguez-Sánchez, Paola García-Padilla, Martha Carolina Valderrama-Rios and Jorge Alberto Cortés
    Citation: BMC Nephrology 2023 24:140
  21. Extra-capillary hypercellularity is a common finding in crescentic glomerulonephritis (GN) and focal segmental glomerulosclerosis (FSGS). In diabetic nephropathy (DN), extra-capillary hypercellularity is often...

    Authors: Madoka Morimoto, Tomoko Namba-Hamano, Shoki Notsu, Yukimasa Iwata, Yumiko Yasuhara, Masafumi Yamato and Yoshitaka Isaka
    Citation: BMC Nephrology 2023 24:139
  22. The mortality of dialysis patients greatly exceeds that of the general population and identifying predictive factors for mortality may provide opportunities for earlier intervention. This study assessed the in...

    Authors: Madeleine Elder, Avalon Moonen, Sjorjina Crowther, Jasna Aleksova, Jacqueline Center and Grahame J. Elder
    Citation: BMC Nephrology 2023 24:138
  23. Karyomegalic interstitial nephritis (KIN) is a rare cause of chronic interstitial nephritis characterized by enlarged renal tubular epithelial nuclei. The first case of KIN reported in a kidney graft was in 20...

    Authors: Fatma El-Husseiny Moustafa, Eman Nagy, Salwa Mahmoud Elwasif and Mohamed Sobh
    Citation: BMC Nephrology 2023 24:137
  24. The relationship between sleep duration and chronic kidney disease (CKD) has received relatively little attention in the Kurdish community. Considering the ethnic diversity of Iran and the importance of the Ku...

    Authors: Niloofar Hemati, Farshad Shiri, Farrokhlegha Ahmadi, Farid Najafi, Mehdi Moradinazar, Ebrahim Norouzi and Habibolah Khazaie
    Citation: BMC Nephrology 2023 24:136
  25. With the constant need for technique improvement for ensuring correct diagnoses and precise treatment, imaging examinations that use contrast media have become unavoidable and indispensable. However, the long-...

    Authors: Tomoyuki Takura, Kosaku Nitta, Ken Tsuchiya and Hideki Kawanishi
    Citation: BMC Nephrology 2023 24:135
  26. Intradialytic hypotension (IDH) is a common clinical complication and is associated with increased morbidity and mortality in patients undergoing maintenance hemodialysis (MHD). The pathogenesis of IDH has bee...

    Authors: Jorge L. Gamboa, Cindy A. Mambungu, Adrienne R. Clagett, Hui Nian, Chang Yu, T. Alp Ikizler and Nancy J. Brown
    Citation: BMC Nephrology 2023 24:134
  27. Acute Kidney Injury (AKI) is frequently seen in hospitalized and critically ill patients. Studies have shown that AKI is a risk factor for the development of acute kidney disease (AKD), chronic kidney disease ...

    Authors: Fateme Nateghi Haredasht, Laban Vanhoutte, Celine Vens, Hans Pottel, Liesbeth Viaene and Wouter De Corte
    Citation: BMC Nephrology 2023 24:133
  28. Tacrolimus trough levels (C0) are used in most transplant centres for therapeutic drug monitoring (TDM) of tacrolimus (Tac). The target range of Tac C0 has been remarkably changed, with a target as low as 3–7 ng/...

    Authors: Thi Van Anh Nguyen, Huu Duy Nguyen, Thi Lien Huong Nguyen, Viet Thang Le, Xuan Kien Nguyen, Viet Tien Tran, Dinh Tuan Le and Ba Thang Ta
    Citation: BMC Nephrology 2023 24:131
  29. Patients on kidney replacement therapy (KRT) are vulnerable to severe illness from COVID-19. Timely, accurate surveillance is essential for planning and implementing infection control at local, regional and na...

    Authors: Shalini Santhakumaran, Manuela Savino, Fran Benoy-Deeney, Retha Steenkamp, James Medcalf and Dorothea Nitsch
    Citation: BMC Nephrology 2023 24:130
  30. Renal impairment in people living with HIV (PWH) in Sub-Saharan Africa is common and associated with increased morbidity and mortality. The ideal equation to estimate glomerular filtration rate (eGFR) in this ...

    Authors: Mitchell Hunter-Dickson, Douglas Drak, Matthew Anderson, Tinei Shamu, Cleophas Chimbetete, Rumbidzai Dahwa and David M. Gracey
    Citation: BMC Nephrology 2023 24:129
  31. Sepsis-related AKI is related to short-term mortality and poor long-term prognoses, such as chronic renal insufficiency, late development of end-stage renal disease, and long-term mortality. In this study, we ...

    Authors: Yuan-Xia Jiang, Chun-Lei Gong, Yan Tang, Yang Yi, Fu-Gang Liu, Jing-Wen Zhou, Ying-Long Shi, Hong-Wei Zhou and Kai-Qing Xie
    Citation: BMC Nephrology 2023 24:128
  32. We present this challenging case report of Atypical Haemolytic Uremic Syndrome (aHUS) presenting with multi-organ involvement in a patient and heterozygous CFHR1/CFHR3 gene variant, which was refractory to ini...

    Authors: Jason Diep, Daniela Potter, Jun Mai and Danny Hsu
    Citation: BMC Nephrology 2023 24:127
  33. The treatment of membranous nephropathy involves a combination of conservative approaches, steroids, and immunosuppressive agents. Infection is an adverse effect of these treatments and its incidence is a crit...

    Authors: Takuro Matsuzaki, Yu Watanabe, Akihito Tanaka, Kazuhiro Furuhashi, Shoji Saito and Shoichi Maruyama
    Citation: BMC Nephrology 2023 24:126
  34. Malnutrition is prevalent in chronic hemodialysis (HD) patients. It increases mortality and negatively affects quality of life. This study aimed to assess the effect of intradialytic oral nutritional supplemen...

    Authors: Mohamed Sary Gharib, Mariem Shaker Nazeih and Tamer Wahid El Said
    Citation: BMC Nephrology 2023 24:125
  35. IgA nephropathy (IgAN) is universally recognized as one of the most common primary glomerular diseases in all ages. Cyclic neutropenia (CN) is a rare haematologic disorder that is associated with mutations of ...

    Authors: C. Kapogiannis, T. Zaggogianni, N. Stergiou, K. Kakleas, A. Kapogiannis, H. Gakiopoulou and C. Kanaka-Gantenbein
    Citation: BMC Nephrology 2023 24:124
  36. A 14-year-old male patient who suffered from limb numbness, fatigue, and hypokalemia was considered Graves’ disease (GD) complicated with thyrotoxic periodic paralysis (TPP) at the first diagnosis. Although wi...

    Authors: Jing Xu, Juan He, Shujing Xu, Rui Wang, Nianchun Peng and Miao Zhang
    Citation: BMC Nephrology 2023 24:123
  37. Physical activity and emotional self-management has the potential to enhance health-related quality of life (HRQoL), but few people with chronic kidney disease (CKD) have access to resources and support. The K...

    Authors: C. G Walklin, Hannah M.L Young, E Asghari, S Bhandari, R. E Billany, N Bishop, K Bramham, J Briggs, J. O. Burton, J Campbell, E. M Castle, J Chilcot, N Cooper, V Deelchand, M. P.M Graham-Brown, A Hamilton…
    Citation: BMC Nephrology 2023 24:122
  38. There is uncertainty about the long-term risks of living kidney donation. Well-designed studies with controls well-matched on risk factors for kidney disease are needed to understand the attributable risks of ...

    Authors: David M. Vock, Erika S. Helgeson, Aidan F. Mullan, Naim S. Issa, Sujana Sanka, Alison C. Saiki, Kristin Mathson, Alanna M. Chamberlain, Andrew D. Rule and Arthur J. Matas
    Citation: BMC Nephrology 2023 24:121
  39. Kidney transplant is the gold standard for renal replacement therapy in patients with autosomal dominant polycystic kidney disease (ADPKD), which is the fourth leading cause of kidney failure. Despite the medi...

    Authors: Juliana Smith, Orlando O. Harris, Deborah Adey and Meyeon Park
    Citation: BMC Nephrology 2023 24:119
  40. Patients with chronic kidney diseases (CKD) are susceptible to the toxic drug effects if given unadjusted doses. Although Pakistan harbors a high burden of CKD patients, there is limited information available ...

    Authors: Muhammad Hayat, Nafees Ahmad, Syed Liaquat Ali Khan, Syed Mohkumuddin, Wajeeha Siddique, Amjad Khan and Muhammad Atif
    Citation: BMC Nephrology 2023 24:118
  41. Kidney transplantation is the gold-standard treatment for patients with kidney failure. However, one-third of patients awaiting a kidney transplant are highly sensitized to human leukocyte antigens (HLA), resu...

    Authors: C Dudreuilh, P Jarvis, N Beadle, I Pilecka, O Shaw, L Gardner, C Scottà, N Mamode, DS Game, A Sanchez-Fueyo, G Lombardi, A Learoyd, A Douiri and A Dorling
    Citation: BMC Nephrology 2023 24:117
  42. Peritoneal dialysis (PD) depends upon a functioning and durable access to the peritoneal cavity. Many techniques exist to insert a peritoneal catheter, showing similar outcomes and benefits. Blind percutaneous...

    Authors: Lucas Jacobs, Mohammed Salaouatchi, Maxime Taghavi, Said Sanoussi, Joelle Nortier and Maria Mesquita
    Citation: BMC Nephrology 2023 24:116
  43. Symptom networks can provide empirical evidence for the development of personalized and precise symptom management strategies. However, few studies have established networks of symptoms experienced by older p...

    Authors: Mingyao Zhou, Xiaoxin Gu, Kangyao Cheng, Yin Wang and Nina Zhang
    Citation: BMC Nephrology 2023 24:115
  44. Renal failure is one of the most serious vascular effects of hypertension. For better therapy and prevention of complications, early kidney disease identification in these patients is absolutely essential. How...

    Authors: Mark Danquah, William K. B. A. Owiredu, B. A. Eghan Jnr, Dorcas Serwaa, Enoch Odame Anto, Maxwell Owusu Peprah, Christian Obirikorang and Linda A. Fondjo
    Citation: BMC Nephrology 2023 24:114
  45. Short-term and long-term blood pressure variability (BPV) in hemodialysis (HD) population are risk factors of cardiovascular diseases (CVD) and all-cause mortality. There is no full consensus on the best BPV m...

    Authors: Qixing Liu, Wei Wang, Xianglan Wu, Jiaxuan Lv, Shiming Cai and Yuehong Li
    Citation: BMC Nephrology 2023 24:113

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