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  1. Infrequent dialysis, namely once-a-week session combined with very low-protein, low-phosphorus diet supplemented with ketoacids was reported as a useful treatment schedule for ESRD patients with markedly reduc...

    Authors: Stefania Caria, Adamasco Cupisti, Giovanna Sau and Piergiorgio Bolasco
    Citation: BMC Nephrology 2014 15:172
    Content type: Research article Published on:

  2. The Southeastern United States has the lowest kidney transplant rates in the nation, and racial disparities in kidney transplant access are concentrated in this region. The Southeastern Kidney Transplant Coali...

    Authors: Rachel E Patzer, Jennifer Gander, Leighann Sauls, M Ahinee Amamoo, Jenna Krisher, Laura L Mulloy, Eric Gibney, Teri Browne, Laura Plantinga and Stephen O Pastan
    Citation: BMC Nephrology 2014 15:171
    Content type: Study protocol Published on:

  3. Hemodialysis patients (HD) need to adhere to a complex medication regimen. Because their daily pill burden is one of the highest reported, poor compliance is a major cause of therapeutic failure. The primary a...

    Authors: Inbal Cohen-Glickman, Yosef S Haviv and Matan J Cohen
    Citation: BMC Nephrology 2014 15:170
    Content type: Research article Published on:

  4. Although intraperitoneal surgery is a major operation associated with postoperative acute kidney injury (AKI), the incidence, risk factors, and long-term renal outcome are not well known. We aimed to determine...

    Authors: Eunjung Cho, Sun-Chul Kim, Myung-Gyu Kim, Sang-Kyung Jo, Won-Yong Cho and Hyoung-Kyu Kim
    Citation: BMC Nephrology 2014 15:169
    Content type: Research article Published on:

  5. Cardiovascular events (CVE) are more prevalent in chronic kidney disease (CKD) than in general population, being the main cause of morbimortality. Specific risk factors related to CKD have been suggested, beca...

    Authors: David Arroyo, Angels Betriu, Montserrat Martinez-Alonso, Teresa Vidal, Jose Manuel Valdivielso and Elvira Fernández
    Citation: BMC Nephrology 2014 15:168
    Content type: Research article Published on:

  6. Early graft thrombosis and bleeding complications remain important causes of early graft loss following kidney transplantation in patients with antiphospholipid syndrome. Anti-β2-glycoprotein I IgG is a diseas...

    Authors: Tadashi Sofue, Yushi Hayashida, Taiga Hara, Kazuyo Kawakami, Nobufumi Ueda, Yoshio Kushida, Masashi Inui, Hiroaki Dobashi, Yoshiyuki Kakehi and Masakazu Kohno
    Citation: BMC Nephrology 2014 15:167
    Content type: Case report Published on:

  7. Because of the deceased donor organ shortage, more kidney patients are considering whether to receive kidneys from family and friends, a process called living donor kidney transplantation (LDKT). Although Blac...

    Authors: Amy D Waterman, Mark L Robbins, Andrea L Paiva, John D Peipert, Crystal S Kynard-Amerson, Christina J Goalby, LaShara A Davis, Jessica L Thein, Emily A Schenk, Kari A Baldwin, Stacy L Skelton, Nicole R Amoyal and Leslie A Brick
    Citation: BMC Nephrology 2014 15:166
    Content type: Study protocol Published on:

  8. Microalbuminuria has been shown to be a risk factor for cardiovascular and renal disease in patients with hypertension and diabetes as well as in the general population. Urinary albumin excretion over 24 h is ...

    Authors: Liuxia Yan, Jixiang Ma, Xiaolei Guo, Junli Tang, Jiyu Zhang, Zilong Lu, Huicheng Wang, Xiaoning Cai and Linhong Wang
    Citation: BMC Nephrology 2014 15:165
    Content type: Research article Published on:

  10. Demineralisation and bone density loss during immobilisation are known phenomena. However information concerning the extent of calcium loss during immobilisation remains inconsistent within literature. This ma...

    Authors: Matthias Klingele, Sarah Seiler, Aaron Poppleton, Philip Lepper, Danilo Fliser and Roland Seidel
    Citation: BMC Nephrology 2014 15:163
    Content type: Case report Published on:

  11. Uraemia is associated with a highly increased risk of cardiovascular disease. Mannose-binding lectin (MBL) has been shown to be involved in cardiovascular pathophysiology and a protective effect of MBL is sugg...

    Authors: Mads Hornum, Jakob T Bay, Peter Clausen, Jesper Melchior Hansen, Elisabeth R Mathiesen, Bo Feldt-Rasmussen and Peter Garred
    Citation: BMC Nephrology 2014 15:162
    Content type: Research article Published on:

  12. Evidence suggests that high dose haemodialysis (HD) may be associated with better health outcomes and even cost savings (if conducted at home) versus conventional in-centre HD (ICHD). Home-based regimens such ...

    Authors: Frank Xiaoqing Liu, Catrin Treharne, Bruce Culleton, Lydia Crowe and Murat Arici
    Citation: BMC Nephrology 2014 15:161
    Content type: Research article Published on:

  13. The definition of glomerular hyperfiltration has not been agreed upon and the pathophysiological mechanisms have not been well explored. Low serum creatinine concentrations may be associated with increased ris...

    Authors: Servet Altay, Altan Onat, Fatma Özpamuk-Karadeniz, Yusuf Karadeniz, Tuğba Kemaloğlu-Öz and Günay Can
    Citation: BMC Nephrology 2014 15:160
    Content type: Research article Published on:

  14. This study aimed to measure the serum soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) and interleukin-17A (IL-17A) levels in hypertensive patients with/without asymptomatic organ damage (...

    Authors: Ihsan Ates, Nihal Özkayar, Fatma Akyel, Canan Topcuoglu, Serdar Akyel, A Nurdan Barça and Fatih Dede
    Citation: BMC Nephrology 2014 15:159
    Content type: Research article Published on:

  15. Acute rejection (AR) and acute tubular necrosis (ATN) are main causes of early renal allograft dysfunction. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) and Diffusion weighted (DW) MRI ca...

    Authors: Guangyi Liu, Fei Han, Wenbo Xiao, Qidong Wang, Ying Xu and Jianghua Chen
    Citation: BMC Nephrology 2014 15:158
    Content type: Research article Published on:

  16. Fabry’s disease is a rare X-linked, hereditary lysosomal storage disease caused by a deficiency of the enzyme α-galactosidase A. Granulomatosis with polyangiitis is characterized by the involvement of the resp...

    Authors: Hironari Hanaoka, Akinori Hashiguchi, Konosuke Konishi, Tomohiro Ishii and Masataka Kuwana
    Citation: BMC Nephrology 2014 15:157
    Content type: Case report Published on:

  17. Proteasome inhibitors are a relatively new class of chemotherapeutic agents. Bortezomib is the first agent of this class and is currently being used for the treatment of multiple myeloma. However, recent repor...

    Authors: Liliane Hobeika, Sally E Self and Juan Carlos Q Velez
    Citation: BMC Nephrology 2014 15:156
    Content type: Case report Published on:

  18. We conducted this study to determine the erythrocyte glucose-6-phosphate dehydrogenase (G6PD) activity level in patients with end-stage renal disease (ESRD) on maintenance hemodialysis (HD) and to determine th...

    Authors: Mahmoud Husni Ayesh (Haj Yousef), Ahnaf Bataineh, Elham Elamin, Yousef Khader, Khaldoon Alawneh and Mohamad Rababah
    Citation: BMC Nephrology 2014 15:155
    Content type: Research article Published on:

  19. Recent research has reported that patients receiving bolus (frequent large doses to achieve iron repletion) versus maintenance dosing of iron have an increased short-term risk of infection, but a similar risk ...

    Authors: Janet K Freburger, Alan R Ellis, Abhijit V Kshirsagar, Lily Wang and M Alan Brookhart
    Citation: BMC Nephrology 2014 15:154
    Content type: Research article Published on:

  20. Chronic kidney disease (CKD) is public health concern even in Asian countries. TRK-100STP, a sustained release tablet of an orally-active prostacyclin analogue, beraprost sodium, is suggested to suppress worse...

    Authors: Hidetomo Nakamoto, Toshiro Fujita, Hideki Origasa, Masanao Isono, Hajimu Kurumatani, Kiyonobu Okada, Hiroyuki Kanoh, Takashi Kiriyama and Shunsuke Yamada
    Citation: BMC Nephrology 2014 15:153
    Content type: Study protocol Published on:

  21. While chronic renal damage is a condition with low-grade inflammation, the potential role of inflammation in kidney disease as a marker of cardiovascular damage is of current interest. This study analyzed the ...

    Authors: Maria Udeanu, Giordano Guizzardi, Giuseppe Di Pasquale, Antonio Marchetti, Francesca Romani, Vittorio Dalmastri, Irene Capelli, Lucia Stalteri, Giuseppe Cianciolo, Paola Rucci and Gaetano La Manna
    Citation: BMC Nephrology 2014 15:152
    Content type: Research article Published on:

  22. Baroreflex failure syndrome is a rare disorder which causes labile blood pressure, headache, flushing, diaphoresis and emotional lability. It is caused by history of trauma or radiotherapy in the cervical legi...

    Authors: Natsumi Tanabe, Koki Takane, Keitaro Yokoyama, Yudo Tanno, Izumi Yamamoto, Ichiro Ohkido and Takashi Yokoo
    Citation: BMC Nephrology 2014 15:151
    Content type: Case report Published on:

  23. The presence of chronic kidney disease (CKD) in type 2 diabetes mellitus (T2DM) increases the risk of cardiovascular disease (CVD) regardless of the presence of traditional cardiovascular risk factors. There i...

    Authors: Antonio Rodriguez-Poncelas, Gabriel Coll-De Tuero, Oriol Turrò-Garriga, Joan Barrot-de la Puente, Josep Franch-Nadal and Xavier Mundet-Tuduri
    Citation: BMC Nephrology 2014 15:150
    Content type: Research article Published on:

  24. Cancer antigen 125 (CA125) is made by peritoneal mesothelial cells and can be measured in spent dialysate effluent from peritoneal dialysis (PD) patients. It has been suggested that CA125 is a marker of perito...

    Authors: Kwanpeemai Panorchan and Andrew Davenport
    Citation: BMC Nephrology 2014 15:149
    Content type: Research article Published on:

  25. Weight gain and obesity are common after kidney transplantation, particularly during the first year. Obesity is a risk factor for the development of new-onset diabetes after transplantation, and is associated ...

    Authors: Kristin J Ryan, Jessie M Segedin Casas, Laura E Mash, Sandra L McLellan, Lyn E Lloyd, James W Stinear, Lindsay D Plank and Michael G Collins
    Citation: BMC Nephrology 2014 15:148
    Content type: Study protocol Published on:

  26. Expression and/or excretion of fibroblast growth factor-23 (FGF23) and its co-receptor Klotho are altered in patients with end-stage renal disease. The possibility that the FGF23/α-Klotho system mediates the a...

    Authors: Michishige Ozeki, Shu-ichi Fujita, Shun Kizawa, Hideaki Morita, Koichi Sohmiya, Masaaki Hoshiga and Nobukazu Ishizaka
    Citation: BMC Nephrology 2014 15:147
    Content type: Research article Published on:

  27. Microalbuminuria is a marker of early kidney disease and high cardiovascular risk in various populations, including HIV positive patients. However, the diagnostic value of qualitative (dipstick) proteinuria an...

    Authors: Mannix Imani Masimango, Ernest Kiswaya Sumaili, Michel Jadoul, Pierre Wallemacq, Dieudonné Kanigula Mubagwa, Rissassy Jean-Robert Makulo, François Bompeka Lepira and Nazaire Mangani Nseka
    Citation: BMC Nephrology 2014 15:146
    Content type: Research article Published on:

  28. Matrix Gla protein (MGP) is known to act as a potent local inhibitor of vascular calcifications. However, in order to be active, MGP must be phosphorylated and carboxylated, with this last process being depend...

    Authors: Pierre Delanaye, Jean-Marie Krzesinski, Xavier Warling, Martial Moonen, Nicole Smelten, Laurent Médart, Hans Pottel and Etienne Cavalier
    Citation: BMC Nephrology 2014 15:145
    Content type: Research article Published on:

  30. The use of herbal medicine may be a risk factor for the development of kidney injury, as it has been reported to cause various renal syndromes. Dioscorea quinqueloba is a medicinal herb that is used as an alterna...

    Authors: Ha Yeon Kim, Sung Sun Kim, Soo Hyeon Bae, Eun Hui Bae, Seong Kwon Ma and Soo Wan Kim
    Citation: BMC Nephrology 2014 15:143
    Content type: Case report Published on:

  31. MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and ...

    Authors: Youqun Huang, Yan Liu, Ling Li, Baihai Su, Lichuan Yang, Wenxin Fan, Qinghua Yin, Lijia Chen, Tianlei Cui, Jie Zhang, Yanrong Lu, Jingqiu Cheng, Ping Fu and Fang Liu
    Citation: BMC Nephrology 2014 15:142
    Content type: Research article Published on:

  32. Focal segmental glomerulosclerosis (FSGS) is a glomerular scarring disease diagnosed mostly by kidney biopsy. Since there is currently no diagnostic test that can accurately predict steroid responsiveness in F...

    Authors: Shiva Kalantari, Mohsen Nafar, Dorothea Rutishauser, Shiva Samavat, Mostafa Rezaei-Tavirani, Hongqian Yang and Roman A Zubarev
    Citation: BMC Nephrology 2014 15:141
    Content type: Research article Published on:

  33. To evaluate the effects of contrast agents containing increasing concentrations of iodine on the renal oxygenation level determined by blood oxygenation level dependent (BOLD) magnetic resonance imaging (MRI) ...

    Authors: Jia-huan Wang, Ke Ren, Wen-ge Sun, Li Zhao, Hong-shan Zhong and Ke Xu
    Citation: BMC Nephrology 2014 15:140
    Content type: Research article Published on:

  34. Effective interventions to improve immunosuppressive medication adherence among adolescent and young adult kidney transplant recipients are desperately needed. This paper describes the aims, design, and method...

    Authors: Bethany J Foster, Ahna Pai, Huaqing Zhao and Susan Furth
    Citation: BMC Nephrology 2014 15:139
    Content type: Study protocol Published on:

  35. Genetic factors are suspected in the pathogenesis of IgA nephropathy, as well as in the course of IgA nephropathy progression towards end stage renal failure. UMOD polymorphism rs12917707 is known to associate wi...

    Authors: Miriana Dinic, Lidia Ghisdal, Judith Racapé, Lise Thibaudin, Philippe Gatault, Marie Essig, Yann Le Meur, Christian Noël, Guy Touchard, Pierre Merville, Zineb Ajarchouh, Christophe Mariat, Marc Abramowicz, Daniel Abramowicz and Eric Alamartine
    Citation: BMC Nephrology 2014 15:138
    Content type: Research article Published on:

  36. Diet can markedly affect acid-base status and it significantly influences chronic kidney disease (CKD) and its progression. The relationship of dietary acid load (DAL) and CKD has not been assessed on a popula...

    Authors: Tanushree Banerjee, Deidra C Crews, Donald E Wesson, Anca Tilea, Rajiv Saran, Nilka Rios Burrows, Desmond E Williams and Neil R Powe
    Citation: BMC Nephrology 2014 15:137
    Content type: Research article Published on:

  37. Socioeconomic status (SES) is independently associated with chronic kidney disease (CKD) progression; however, its association with other CKD outcomes is unclear. In particular, the potential differential effe...

    Authors: Stacey A Fedewa, William M McClellan, Suzanne Judd, Orlando M Gutiérrez and Deidra C Crews
    Citation: BMC Nephrology 2014 15:136
    Content type: Research article Published on:

  38. Diabetic nephropathy (DN) is the leading cause of chronic kidney disease and is associated with excessive cardiovascular morbidity and mortality. The angiotensin converting enzyme inhibitor (ACEI) benazepril h...

    Authors: Honglin Niu, Lei Nie, Maodong Liu, Yanqing Chi, Tao Zhang and Ying Li
    Citation: BMC Nephrology 2014 15:135
    Content type: Research article Published on:

  39. Patients with end-stage renal disease (ESRD) have multiple comorbid conditions. Obtaining comorbidity data from medical records is cumbersome. A self-report comorbidity questionnaire is a useful alternative. O...

    Authors: Sivakumar Sridharan, Jocelyn Berdeprado, Enric Vilar, Justin Roberts and Ken Farrington
    Citation: BMC Nephrology 2014 15:134
    Content type: Research article Published on:

  40. A translational study in renal transplantation suggested YKL-40, a chitinase 3-like-1 gene product, plays an important role in acute kidney injury (AKI) and repair, but data are lacking about this protein in u...

    Authors: Isaac E Hall, Edward P Stern, Lloyd G Cantley, Jack A Elias and Chirag R Parikh
    Citation: BMC Nephrology 2014 15:133
    Content type: Research article Published on:

  41. Recommendations for secondary hyperparathyroidism (SHPT) consider that a “one-size-fits-all” target enables efficacy of care. In routine clinical practice, SHPT continues to pose diagnosis and treatment challe...

    Authors: Emmanuelle Laurain, Carole Ayav, Marie-Line Erpelding, Michèle Kessler, Serge Briançon, Laurent Brunaud and Luc Frimat
    Citation: BMC Nephrology 2014 15:132
    Content type: Research article Published on:

  42. Poor sleep quality, a novel risk factor of cardiovascular diseases (CVD), is highly prevalent in patients with chronic kidney disease (CKD). The association between poor sleep quality and cardiovascular damage...

    Authors: Jun Zhang, Cheng Wang, Wenyu Gong, Hui Peng, Ying Tang, Cui Cui Li, Wenbo Zhao, Zengchun Ye and Tanqi Lou
    Citation: BMC Nephrology 2014 15:131
    Content type: Research article Published on:

  43. The risk of cardiovascular disease is tremendously high in dialysis patients. Dialysis patients treated with vitamin D analogs show decreased cardiovascular morbidity and mortality compared with untreated pati...

    Authors: Ditte Hansen, Knud Rasmussen, Lars M Rasmussen, Helle Bruunsgaard and Lisbet Brandi
    Citation: BMC Nephrology 2014 15:130
    Content type: Research article Published on:

  44. Patients with end-stage kidney disease (ESKD) have a high rate of mortality and specifically an increased risk of sudden cardiac death (SCD). Impaired cardiac autonomic tone is associated with elevated risk of...

    Authors: Michelle C Mann, Derek V Exner, Brenda R Hemmelgarn, David A Hanley, Tanvir C Turin, Jennifer M MacRae and Sofia B Ahmed
    Citation: BMC Nephrology 2014 15:129
    Content type: Study protocol Published on:

  45. Double filtration plasmapheresis (DFPP) and (IA) are both used to clear antibody. However, the clinical efficacy and safety of DFPP in patients with anti-glomerular basement membrane (anti-GBM) disease are unc...

    Authors: Yi-yan Zhang, Zheng Tang, Dong-mei Chen, De-hua Gong, Da-xi Ji and Zhi-hong Liu
    Citation: BMC Nephrology 2014 15:128
    Content type: Research article Published on:

  47. Intratracheal aspiration and sepsis are leading causes of acute lung injury that frequently necessitate mechanical ventilation (MV), which may aggravate lung injury thereby potentially increasing the risk of a...

    Authors: Jan Willem Kuiper, AB Johan Groeneveld, Jack J Haitsma, Lonneke Smeding, Mark PV Begieneman, Serge Jothy, Rosanna Vaschetto and Frans B Plötz
    Citation: BMC Nephrology 2014 15:126
    Content type: Research article Published on:

  48. The recent emergence of an apparently new form of chronic kidney disease of unknown aetiology (CKDu) has become a serious public health crisis in Sri Lanka. CKDu is slowly progressive, irreversible, and asympt...

    Authors: Jennifer Hoponick Redmon, Myles F Elledge, Donna S Womack, Rajitha Wickremashinghe, Kamani P Wanigasuriya, Roshini J Peiris-John, Joseph Lunyera, Kristin Smith, James H Raymer and Keith E Levine
    Citation: BMC Nephrology 2014 15:125
    Content type: Correspondence Published on:

  50. Neutrophil gelatinase-associated lipocalin (NGAL) is a marker for acute kidney injury. We studied whether serum NGAL predicts delayed graft function (DGF) and recovery of kidney function after transplantation.

    Authors: Maria E Hollmen, Lauri E Kyllönen, Jussi Merenmies and Kaija T Salmela
    Citation: BMC Nephrology 2014 15:123
    Content type: Research article Published on:
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BMC Nephrology

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