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  1. The degree to which genetic or environmental factors are associated with early kidney damage among African Americans (AAs) is unknown.

    Authors: Ruth Tamrat, Carmen A Peralta, Salman M Tajuddin, Michele K Evans, Alan B Zonderman and Deidra C Crews
    Citation: BMC Nephrology 2015 16:14
  2. Polycystic kidney disease (PKD), a genetic disorder characterized by multiple cysts and renal failure at an early age. In children, kidney disease is often accompanied by disordered mineral metabolism, failure...

    Authors: Kaitlin H Maditz, Brenda J Smith, Matthew Miller, Chris Oldaker and Janet C Tou
    Citation: BMC Nephrology 2015 16:13
  3. Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HB...

    Authors: Luciana Sowole, Wendy Labbett, Mauli Patel, Aisling O’Riordan, Jennifer Cross, Andrew Davenport and Tanzina Haque
    Citation: BMC Nephrology 2015 16:12
  4. Mortality rate among patients with stage five chronic kidney disease (CKD) maintained on hemodialysis (HD) is high. Although evidence suggests that use of Vitamin D Receptor Activators (VDRA) in CKD patients i...

    Authors: Piergiorgio Messa, Mario Cozzolino, Diego Brancaccio, Giuseppe Cannella, Fabio Malberti, Anna Maria Costanzo, Umberto di Luzio Paparatti, Vincenzo Festa, Giuliana Gualberti and Sandro Mazzaferro
    Citation: BMC Nephrology 2015 16:11
  5. Kimura's disease (KD) is a slowly progressing rare, benign inflammatory disorder of the soft tissues. It typically presents as subcutaneous tumor-like nodules, located most frequently in the head and neck regi...

    Authors: Sheng-lang Zhu, Peng-fei Wei, Jie-hui Chen, Zhen-fu Zhao, Qian-na Xu and Ling Ye
    Citation: BMC Nephrology 2015 16:10
  6. Variants in CUBN, the gene encoding cubilin, a proximal tubular transport protein, have been associated with albuminuria and vitamin B12 (B12) deficiency. We hypothesized that low levels of B12 would be associate...

    Authors: Gearoid M McMahon, Shih-Jen Hwang, Rikki M Tanner, Paul F Jacques, Jacob Selhub, Paul Muntner and Caroline S Fox
    Citation: BMC Nephrology 2015 16:7
  7. Numerous well-established clinical parameters are taken into consideration for the follow-up adaptation of kidney transplant recipients, but there are important disparities between countries, centres and clini...

    Authors: Yohann Foucher, Aurélie Meurette, Pascal Daguin, Angélique Bonnaud-Antignac, Jean-Benoît Hardouin, Sabrina Chailan, Karine Neau, Emmanuelle Papuchon, Sandra Gaboriau, Christophe Legendre, Emmanuel Morélon, Philippe Tessier and Magali Giral
    Citation: BMC Nephrology 2015 16:6
  8. Urinary albumin can be measured in 24 h or spot samples. The 24 h urinary albumin excretion rate is considered the gold standard, but is cumbersome to collect. Instead, often an overnight sample is collected, ...

    Authors: Peter Fagerstrom, Gerd Sallsten, Magnus Akerstrom, Borje Haraldsson and Lars Barregard
    Citation: BMC Nephrology 2015 16:8
  9. Phosphorus retention plays a pivotal role in the onset of mineral and bone disorders (MBD) in chronic kidney disease (CKD). Phosphorus retention commonly occurs as a result of net intestinal absorption exceedi...

    Authors: Claudia D’Alessandro, Giorgina B Piccoli and Adamasco Cupisti
    Citation: BMC Nephrology 2015 16:9
  10. Acute kidney injury (AKI) is a common complication of sepsis. We determined the prevalence of AKI among adult patients with sepsis on the medical wards in a low-income country and described their clinical patt...

    Authors: Peace Bagasha, Frederick Nakwagala, Arthur Kwizera, Emmanuel Ssekasanvu and Robert Kalyesubula
    Citation: BMC Nephrology 2015 16:4
  11. Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known.

    Authors: Elaine Ku, Kirsten L Johansen, Anthony A Portale, Barbara Grimes and Chi-yuan Hsu
    Citation: BMC Nephrology 2015 16:2
  12. There is a recent debate on the "transplantability" of ECD (Expanded Criteria Donors) kidneys and the selection criteria used to allocate them to single or double transplantation. Remuzzi et al. have defined a...

    Authors: Carlo Grifasi, Vincenzo D’Alessandro, Maria D’Armiento, Severo Campione, Alessandro Scotti, Luigi Pelosio and Andrea Renda
    Citation: BMC Nephrology 2014 15:207
  13. The significant impact Acute Kidney Injury (AKI) has on patient morbidity and mortality emphasizes the need for early recognition and effective treatment. AKI presenting to or occurring during hospitalisation ...

    Authors: Helen Hobbs, Paul Bassett, Toby Wheeler, Michael Bedford, Jean Irving, Paul E Stevens and Christopher KT Farmer
    Citation: BMC Nephrology 2014 15:206
  14. The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables ...

    Authors: Soo Min Jang, Katie E Cardone, Thomas D Nolin, Darius L Mason and Darren W Grabe
    Citation: BMC Nephrology 2014 15:204
  15. AKI frequently develops in sepsis patients, significantly decreasing the overall prognosis. There are currently no diagnostic markers available which reliably predict the prognosis of sepsis-associated AKI. Re...

    Authors: Daniel Patschan, Malte Heeg, Maria Brier, Gunnar Brandhorst, Simon Schneider, Gerhard A Müller and Michael J Koziolek
    Citation: BMC Nephrology 2014 15:203
  16. This study was performed to evaluate the effectiveness of surveillance for screening and treatment of patients with chronic kidney disease undergoing hemodialysis and colonized by Staphylococcus aureus.

    Authors: Cibele Grothe, Mônica Taminato, Angélica Belasco, Ricardo Sesso and Dulce Barbosa
    Citation: BMC Nephrology 2014 15:202
  17. Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF)....

    Authors: Ana Paula Bernardo, José C Oliveira, Olívia Santos, Maria J Carvalho, António Cabrita and Anabela Rodrigues
    Citation: BMC Nephrology 2014 15:201
  18. Although most outpatients are relatively healthy, many have chronic renal insufficiency, and high override rates for suggestions on renal dosing have been observed. To better understand the override of renal d...

    Authors: Insook Cho, Sarah P Slight, Karen C Nanji, Diane L Seger, Nivethietha Maniam, Patricia C Dykes and David W Bates
    Citation: BMC Nephrology 2014 15:200
  19. Diabetic patients with chronic kidney disease (CKD), as defined by a reduced glomerular filtration rate (GFR), are at greater risk for cardiovascular and renal events and mortality. The aim of this study was t...

    Authors: Temesgen Fiseha, Mehidi Kassim and Tilahun Yemane
    Citation: BMC Nephrology 2014 15:198
  20. Dialysis patients suffer from a high burden of cardiovascular disease (CVD). Partly this is due to progressive deterioration of calcium-phosphate homeostasis. Previous studies suggested that besides FGF-23, lo...

    Authors: Maurits S Buiten, Mihály K de Bie, Annet Bouma-de Krijger, Bastiaan van Dam, Friedo W Dekker, J Wouter Jukema, Ton J Rabelink and Joris I Rotmans
    Citation: BMC Nephrology 2014 15:197
  21. Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly relate...

    Authors: Miriana Dinic, Nicolas Maillard, Damien Thibaudin, Martin Jannot, Ingrid Masson, Eric Alamartine and Christophe Mariat
    Citation: BMC Nephrology 2014 15:196
  22. Little is known about patients’ and carers’ experiences of interacting with home haemodialysis (HHD) technology, in terms of user experience, how the design of the technology supports safety and fits with home...

    Authors: Atish Rajkomar, Ken Farrington, Astrid Mayer, Diane Walker and Ann Blandford
    Citation: BMC Nephrology 2014 15:195
  23. Factors influencing the use of dietary interventions for modification of CKD risk among African Americans have not been well-explored. We assessed perceived barriers and facilitators of CKD prevention through ...

    Authors: Amber E Johnson, L Ebony Boulware, Cheryl AM Anderson, Tatpong Chit-ua-aree, Kimberly Kahan, LaPricia Lewis Boyér, Yang Liu and Deidra C Crews
    Citation: BMC Nephrology 2014 15:194
  24. The risk of end stage renal disease (ESRD) is increased among individuals with low income and in low income communities. However, few studies have examined the relation of both individual and community socioec...

    Authors: Deidra C Crews, Orlando M Gutiérrez, Stacey A Fedewa, Jean-Christophe Luthi, David Shoham, Suzanne E Judd, Neil R Powe and William M McClellan
    Citation: BMC Nephrology 2014 15:192
  25. Little is known how health related quality of life (HRQOL) change in the transition from dialysis to renal transplantation (RTX). Longitudinal data addressing the patient-related outcomes are scarce, and parti...

    Authors: Nanna von der Lippe, Bård Waldum, Fredrik B Brekke, Amin AG Amro, Anna Varberg Reisæter and Ingrid Os
    Citation: BMC Nephrology 2014 15:191
  26. Sclerostin (Scl) has recently emerged as a novel marker of bone remodeling and vascular calcification. However, whether high circulating Scl is also a risk factor for death is not well established. The purpose...

    Authors: Flávia Letícia Carvalho Gonçalves, Rosilene M Elias, Luciene M dos Reis, Fabiana G Graciolli, Fernando Godinho Zampieri, Rodrigo B Oliveira, Vanda Jorgetti and Rosa MA Moysés
    Citation: BMC Nephrology 2014 15:190
  27. Excess extracellular volume is a major clinical problem in patients with chronic kidney disease (CKD). However, whether the extracellular volume status is associated with disease progression is unclear. We inv...

    Authors: Reibin Tai, Yasushi Ohashi, Sonoo Mizuiri, Atsushi Aikawa and Ken Sakai
    Citation: BMC Nephrology 2014 15:189
  28. Impairments of health related quality of life (HRQoL) are frequently observed in Fabry disease (FD) and are known to be related to neuropathic pain and cardiovascular events. This study aimed to explore the ro...

    Authors: Martin Wagner, Johannes Krämer, Elisabeth Blohm, Dorothee Vergho, Frank Weidemann, Frank Breunig and Christoph Wanner
    Citation: BMC Nephrology 2014 15:188
  29. Only a subset of patients who enter stage 3 chronic kidney disease (CKD) progress to stage 4. Identifying which patients entering stage 3 are most likely to progress could improve outcomes, by allowing more ap...

    Authors: Herbert S Chase, Jamie S Hirsch, Sumit Mohan, Maya K Rao and Jai Radhakrishnan
    Citation: BMC Nephrology 2014 15:187
  30. This study was aimed at determining the outcome and examining the association between comorbidities and mortality after intracerebral hemorrhage in chronic dialysis patients.

    Authors: Chun-Yu Lin, Chih-Chiang Chien, Hung-An Chen, Fu-Mei Su, Jhi-Joung Wang, Che-Chuan Wang, Chin-Chen Chu and Yeong-Jang Lin
    Citation: BMC Nephrology 2014 15:186
  31. Chronic Kidney Disease (CKD) is a major non-communicable chronic disease that is associated with adverse clinical and economic outcomes. Passive surveillance systems are likely to improve efforts for preventio...

    Authors: Austin G Stack, Liam F Casserly, Cornelius J Cronin, Tetyana Chernenko, Walter Cullen, Ailish Hannigan, Rajiv Saran, Howard Johnson, Gemma Browne and John P Ferguson
    Citation: BMC Nephrology 2014 15:185
  32. Mineral disorders are associated with adverse renal outcomes in chronic kidney disease (CKD) patients. Previous studies have associated hypercalcemia and hypocalcemia with mortality; however, the association b...

    Authors: Lee-Moay Lim, Hung-Tien Kuo, Mei-Chuan Kuo, Yi-Wen Chiu, Jia-Jung Lee, Shang-Jyh Hwang, Jer-Chia Tsai, Chi-Chih Hung and Hung-Chun Chen
    Citation: BMC Nephrology 2014 15:183
  33. Autosomal dominant polycystic kidney disease (ADPKD) causes progressive renal damage and is a leading cause of end-stage renal failure. With emerging therapies it is important to devise a method for early dete...

    Authors: Andrew P McGovern, Simon Jones, Jeremy van Vlymen, Anand K Saggar, Richard Sandford and Simon de Lusignan
    Citation: BMC Nephrology 2014 15:182
  34. This study aimed to compare the changes in kidney function and the association of tumor size and renal outcomes between patients with renal cell carcinoma (RCC) who underwent radical nephrectomy (RN) and those...

    Authors: Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Sun-Seog Kweon and Soo Wan Kim
    Citation: BMC Nephrology 2014 15:181
  35. Type 2 diabetes is a major risk factor for chronic kidney disease, which substantially increases the risk of cardiovascular disease mortality. This Phase IIb safety study (AleNephro) in patients with stage 3 c...

    Authors: Luis Ruilope, Markolf Hanefeld, A Michael Lincoff, Giancarlo Viberti, Sylvie Meyer-Reigner, Nadejda Mudie, Dominika Wieczorek Kirk, Klas Malmberg and Matthias Herz
    Citation: BMC Nephrology 2014 15:180
  36. Guidance varies regarding the optimal timing of arteriovenous fistula (AVF) creation. The aim of this study was to evaluate the association between uraemia, haemodialysis and early AVF failure.

    Authors: Emma Aitken, Andrew Jackson, Chia Kong, Paul Coats and David Kingsmore
    Citation: BMC Nephrology 2014 15:179
  37. Death receptors (DRs) play an important role in renal pathology. We have shown that DR3 is inducibly expressed on renal tubular epithelial cells in the setting of inflammatory injuries. In this study we invest...

    Authors: Jun Wang, Rafia S Al-Lamki, Xinwang Zhu, Hanzhe Liu, Jordan S Pober and John R Bradley
    Citation: BMC Nephrology 2014 15:178
  38. New information from various clinical settings suggests that tight blood pressure control may not reduce mortality and may be associated with more side effects.

    Authors: Adrian P Abreo, David Glidden, Patricia Painter, Janice Lea, Charles A Herzog, Nancy G Kutner and Kirsten L Johansen
    Citation: BMC Nephrology 2014 15:177
  39. In the current acute kidney injury (AKI) definition, the urine output (UO) criterion does not specify which body weights (BW), i.e. actual (ABW) versus ideal (IBW), should be used to diagnose and stage AKI, le...

    Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Abbasali Akhoundi, Adil H Ahmed and Kianoush B Kashani
    Citation: BMC Nephrology 2014 15:176
  40. Collagen IV-related nephropathies, including thin basement membrane nephropathy and Alport Syndrome (AS), are caused by defects in the genes COL4A3, COL4A4 and COL4A5. Diagnosis of these conditions can be hindere...

    Authors: Fujun Lin, Fan Bian, Jun Zou, Xiangru Wu, Jianping Shan, Wei Lu, Yao Yao, Gengru Jiang and Daniel Philip Gale
    Citation: BMC Nephrology 2014 15:175
  41. Cardiovascular disease is a frequent cause of death in peritoneal dialysis patients. Biocompatible peritoneal dialysis solutions with neutral pH have been anticipated to reduce cardiovascular disease more than...

    Authors: Yoshifumi Hamasaki, Kent Doi, Mototsugu Tanaka, Haruki Kume, Yoshitaka Ishibashi, Yutaka Enomoto, Toshiro Fujita, Yukio Homma, Masaomi Nangaku and Eisei Noiri
    Citation: BMC Nephrology 2014 15:173
  42. Infrequent dialysis, namely once-a-week session combined with very low-protein, low-phosphorus diet supplemented with ketoacids was reported as a useful treatment schedule for ESRD patients with markedly reduc...

    Authors: Stefania Caria, Adamasco Cupisti, Giovanna Sau and Piergiorgio Bolasco
    Citation: BMC Nephrology 2014 15:172

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