Table 1 Characteristics of patients at baseline
Number of patients | 58 (100%) |
Age | 49 [23–89] |
Male | 49 (68.9%) |
Blood pressure (mmHg) | |
Systolic | 130 (88–181) |
Diastolic | 78 (59–115) |
Pulse pressure | 50 (28–80) |
Renal function | |
Serum creatinine (μmol/L) | 124 (54–906) |
eGFR (ml/min/1,73m 2 ) | 59 (5–130) |
Proteinuria/creatininuria(mg/mmol) | 245 (7–2000) |
Antihypertensive treatments | |
No antihypertensive drug | 27 (46.5%) |
1 antihypertensive drug | 11 (19%) |
2 antihypertensive drugs | 9 (15.5%) |
≥ 3 antihypertensive drugs | 11 (19%) |
RAS blockers | 23 (39.6%) |
Renal biopsy | |
% sclerotic glomeruli | 13 (0–96) |
% interstitial fibrosis | 10 (0–90) |
Vascular lesions | 34/51 (66.7%) |
Arteriolar hyaline deposits | 25/53 (47.2%) |
Intima/media ratio | |
Normal | 25 (54.4%) |
< 1 | 13 (28.3%) |
≥ 1 | 8 (17.3%) |
Diagnosis | |
FSGN/HIVAN | 9 (15.5%) |
IgA nephropathy | 11 (19%) |
Membranous nephropathy | 7 (12.1%) |
Minimal change disease | 3 (5.2%) |
Lupus | 3 (5.2%) |
Vascularitis | 3 (5.2%) |
Membranous proliferative nephritis | 2 (3.4%) |
Diabetes | 2 (3.4%) |
Amyloidosis | 2 (3.4%) |
Other glomerulonephritis | 5 (8.6%) |
Acute tubulo-interstitial nephritis | 3 (1.7%) |
Chronic tubulo-interstitial nephritis | 2 (3.4%) |
Vascular nephropathy | 2 (3.4%) |
Other | 4 (6.9%) |
Renal arterial resistive index | 0.62 (0.31-1.00) |