Table 3 Mean (95% CI) difference between the CKD-EPI and MDRD equation estimates (defined as CKD-EPI – MDRD ), stratified by level of renal function using CKD–EPI equation as reference, age (<65 years compared to ≥65 years) and gender N (Males:%), in a randomly selected representative sample of middle and older aged Irish population
CKD-EPI eGFR≥60ml/min1 | |||
|---|---|---|---|
All | <65 years | ≥65 years | |
N=968 | N=716 | N=252 | |
Males: 46% | Males: 42% | Males: 52% | |
Females: 54% | Females: 58% | Females: 48% | |
All | 4.9 (4.5, 5.2) 1 | 6.4 (6.0, 6.8) 2 | 0.6 (−0.2, 1. 4) 3 |
Males | 3.43 (2.9, 3.9) | 5.1 (4.6, 5.6) | -.0.3 (−1.4, 0.9) |
Females | 6.03 (5.5, 6.6) | 7.4 (6.8, 8.0) | 1.7 (0.4, 2.7) |
p value 4 | 0.0001 | 0.0001 | 0.025 |
CKD-EPI eGFR<60ml/min 1 | |||
All | <65 years | ≥65 years | |
N=130 | N=31 | N=99 | |
Males: 50% | Males: 35% | Males: 52% | |
Females: 50% | Females: 65% | Females: 48% | |
All | 1.1 (0.8, 1.5) 1 | 3.7 (3.3, 4.1) 2 | 0.3 (0.03,0.6) 3 |
Males | 0.2 (−0.2, 0.7) | 3.3 (2.6, 4.0) | −0.4 (−0.8, -0.1) |
Females | 1.7 (1.3, 2.1) | 3.9 (3.4, 4.4) | 1.2 (0.8, 1.5) |
p value 4 | 0.0001 | 0.16 | 0.0001 |