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Table 4 Multivariate analysis of chronic kidney disease impact on the prevalence of cardiovascular disease

From: Impact of chronic kidney disease on the prevalence of cardiovascular disease in patients with type 2 diabetes in Spain: PERCEDIME2 study

  Unadjusted model (OR; CI95%) Model 1 (OR; CI95%) Model 2 (OR; CI95%) Model 3 (OR; CI95%)
Glomerular filtration rate (eGFR)     
eGFR ≥ 60 mL/min/1.73 m2 1 1 1 1
eGFR 45–59 mL/min/1.73 m2 2.07 (1.5-2.8) 1.2 (0.9-1.7) 1.2 (0.9-1.8) 1.2 (0.9-1.8)
eGFR 30–44 mL/min/1.73 m2 4.6 (2.9-7.3) 2.5 (1.5-4.1) 2.3 (1.4-3.8) 2.3 (1.4-3.9)
eGFR < 30 mL/min/1.73 m2 8.4 (3.6-19.9) 4.3 (1.7-10.7) 4.1 (1.6-10.2) 4.1 (1.6-10.2)
For each unit below 60 mL/min/1.73 m2 1.072 (1.06-1.09) 1.045 (1.03-1.06) 1.042 (1.02-1.06) 1.043 (1.02-1.06)
UACR     
Normoalbuminuria 1 1 1 1
Microlbuminuria (30–299 mg/gr) 1.9 (1.4-2.7) 1.8 (1.2-2.6) 1.8 (1.3-2.7) 1.6 (1.1-2.4)
Macroalbuminuria (≥300 mg/gr) 5.0 (2.3-11.1) 4.6 (1.9-10.9) 4.2 (1.8-10.2) 3.9 (1.6 -9.5)
For each unit above 29 mg/gr 1.001 (0.99-1.01) 1.001 (0.99-1.01) 1.001 (0.99-1.01) 1.001 (0.99-1.01)
UACR (normal) + GFR (normal) 1 1 1 1
UACR ↑ and eGFR ↓ 3.3 (1.5-7.3) 2.3 (1.0-5.3) 2.4 (1.0-5.4) 2.2 (0.9-5.2)
  1. GFR: estimated glomerular filtration rate. eGFR (normal): ≥ 60 mL/min/1,73 m2. eGFR↓: < 60 mL/min/1,73 m2.
  2. UACR: Urine albumin/creatinine ratio . UACR (normal) < 30 mg/g. UACR ↑: ≥ 30 mg/g.
  3. Normoalbuminuria: UACR < 30 mg/g. Microalbuminuria: UACR = 30–299 mg/g . Macroalbuminuria: UACR >300 mg/g.
  4. Model 1 Adjusted for age and sex.
  5. Model 2 Adjusted for age, sex, hypertension, dislipidaemia, tobacco and Body Mass Index.
  6. Model 3 Adjusted for age, sex, hypertension, dislipidaemia , tobacco, Body Mass Index , HbA1c and T2DM duration.