Figure 3
From: Fabry nephropathy: a review – how can we optimize the management of Fabry nephropathy?
Change in eGFR in patients with Fabry disease and CKD during treatment with agalsidase alfa. Republished with permission of Elsevier, from [Enzyme replacement therapy with agalsidase alfa in patients with Fabry’s disease: an analysis of registry data. Mehta A et al. Lancet 374: 2009]; permission conveyed through Copyright Clearance Centre, Inc. [68]. Data are plotted according to baseline stage of CKD. Patient numbers are shown in parentheses. Data from previous studies for the expected natural fall in renal function in patients with Fabry disease and the effects of agalsidase beta are plotted for reference and comparison. *[69]; †[70]; ‡[18]; §[41]; ¶[63]; ||[26]. CKD, chronic kidney disease; GFR, glomerular filtration rate.