Table 2 Performance of dual- and single- sampling methods at different GFR levelsa
Variable | mGFR (ml/min/1.73m2) | ||
|---|---|---|---|
< 60 (n = 58) | 60–89 (n = 42) | > 90 (n = 70) | |
Bias ─ Mean Difference (95% CI) | |||
GFR23 | 1.05 (−0.10,1.7) | −0.17 (− 1.29,0.11) | −0.47 (− 1.10,-0.10) |
GFR34 | − 0.75 (−1.3,-0.19) | 0.35 (− 1.29,1.63) | 2.71 (0.83,4.85) |
GFR24 | − 0.02 (− 0.12,0.02) | −0.73 (− 1.15,0.09) | −0.86 (− 1.30,-0.28) |
GFR2 | − 0.88 (−4.39,4.51) | 0.04 (− 1.64,2.27) | 1.19 (− 0.04,1.75) |
GFR3 | 1.31 (− 1.38,4.69) | 1.76 (0.91,2.74) | −1.73 (− 3.54,0.26) |
GFR4 | 0.43 (− 0.57,1.74) | 0.40 (− 0.95,1.83) | −5.89 (−7.95,3.76) |
Precision ─ IQR (95% CI) | |||
GFR23 | 5.56 (1.82,8.73) | 3.92 (1.25,7.18) | 1.79 (1.30,3.03) |
GFR34 | 3.59 (1.36,7.21) | 3.75 (1.39,9.56) | 7.02 (4.64,12.64) |
GFR24 | 0.71 (0.21,1.39) | 1.79 (0.88,3.10) | 1.84 (1.17,2.89) |
GFR2 | 21.99 (9.43,32.91) | 5.35 (3.24,12.48) | 3.45 (2.16,5.02) |
GFR3 | 9.94 (6.26,14.68) | 4.68 (1.36,6.84) | 6.99 (4.15,11.14) |
GFR4 | 4.93 (2.58,9.27) | 3.89 (2.40,12.12) | 9.18 (4.96,14.11) |
Accuracyb ─ % (95% CI) | |||
P30 | |||
GFR23 | 96.8 (87.9100) | 100c | 100c |
GFR34 | 91.4 (82.8,98.3) | 100c | 98.6 (95.7100) |
GFR24 | 100c | 100c | 100c |
GFR2 | 55.2 (43.1,69.0) | 97.6 (92.9100) | 100c |
GFR3 | 72.4 (60.3,84.5) | 100c | 100c |
GFR4 | 82.8 (72.4,91.4) | 100c | 100c |
P10 | |||
GFR23 | 60.34 (46.6,72.4) | 92.9 (85.7100) | 97.1 (92.9100) |
GFR34 | 65.5 (53.5,77.6) | 83.3 (71.4,92.9) | 87.1 (78.6,94.3) |
GFR24 | 100c | 100c | 98.6 (95.7100) |
GFR2 | 25.9 (13.8,36.2) | 78.6 (66.7,90.5) | 97.1 (92.9100) |
GFR3 | 41.4 (29.3,55.2) | 90.5 (81.0,97.6) | 92.9 (87.1,98.6) |
GFR4 | 65.5 (51.8,77.6) | 88.1 (78.6,97.6) | 78.6 (68.6,88.6) |