Table 3 Incidence of hospitalization due to chronic kidney disease in relation to complement C3 quartiles (Q1-Q4)

C3 range (g/L)

<1.3

1.31–1.49

1.50–1.71

>4.05

No. of subjects

1069

1195

1145

1143

–

Incidence (main diagnosis) ^b

7

16

26

45

–

Incidence (per 1000 person-years)

0.33

0.69

1.20

2.09

–

Model 1 ^d

Reference

2.09 (0.86, 5.07) ^c

3.63 (1.58, 8.36)

6.46 (2.91, 14.3)

<0.001

Model 2 ^e

Reference

1.86 (0.77, 4.53)

3.14 (1.36, 7.24)

5.82 (2.62, 12.9)

<0.001

Model 3 ^f

Reference

1.68 (0.69, 4.13)

2.71 (1.15, 6.39)

3.16 (1.36, 7.34)

0.003

Incidence (main or contributing diagnosis) ^g

20

38

51

77

–

Incidence (per 1000 person-years)

0.96

1.65

2.35

3.60

–

Model 1 ^d

Reference

1.74 (1.01, 2.98)

2.50 (1.49, 4.19)

3.89 (2.38, 6.37)

<0.001

Model 2 ^e

Reference

1.50 (0.87, 2.58)

2.07 (1.23, 3.48)

3.46 (2.12, 5.66)

<0.001

Model 3 ^f

Reference

1.39 (0.81, 2.40)

1.50 (0.88, 2.55)

1.73 (1.02, 2.92)

0.047