| | Mean ± SD of C3 | No. of subjects | Incidence | HR (95%CI) |
P
|
|---|
Whole study population | 1.548 ± 0.353 | 4552 | 94 | 1.28 (1.08, 1.53) | 0.005 |
Model 1 b | 1.529 ± 0.341 | 4196 | 73 | 1.35 (1.10, 1.66) | 0.004 |
Model 2 c | 1.528 ± 0.341 | 4186 | 63 | 1.39 (1.11, 1.73) | 0.004 |
Model 3 d | 1.511 ± 0.330 | 3802 | 63 | 1.46 (1.17, 1.82) | 0.001 |
Model 4 e | 1.515 ± 0.332 | 3867 | 64 | 1.43 (1.13, 1.81) | 0.003 |
Model 5 f | 1.475 ± 0.343 | 1658 | 81 | 1.65 (1.16, 2.35) | 0.005 |
Model 6 g | 1.544 ± 0.351 | 4479 | 87 | 1.27 (1.06, 1.52) | 0.010 |
Model 7 h | 1.548 ± 0.350 | 1842 | 32 | 1.57 (1.18, 2.09) | 0.002 |
Model 8 i | 1.548 ± 0.354 | 4396 | 91 | 1.26 (1.06, 1.51) | 0.011 |
Model 9 j | 1.546 ± 0.352 | 4467 | 79 | 1.25 (1.04, 1.50) | 0.018 |
- aHR hazard ratios, CI confidence interval, CKD chronic kidney disease, SD standard deviation; adjusted for age, sex, waist circumference, smoking and drinking habits, low-density lipoprotein cholesterol, diabetes, cardiovascular disease, anti-hypertensive drug medication, and baseline estimated glomerular filtration rate (specific covariate was not adjusted when being investigated in a specific model)
- bExcluding participants with baseline diabetes
- cExcluding participants with previous or concomitant diabetes before incident chronic kidney disease
- dExcluding participants with baseline diabetes or incident diabetes during follow-up
- eExcluding participants with baseline diabetes or impair fasting glucose (fasting glucose ≥5.6 mmol/L)
- fExcluding participants with baseline hypertension
- gExcluding participants with baseline cardiovascular disease
- hExcluding current, occasional or former smokers
- iExcluding participants with high alcohol consumption
- jExcluding participants with estimated glomerular filtration rate < 60 mL/min per 1.73 m2
