Fig. 6

PAS staining b, d and UMOD immunostaining a, c of a series of ADTKD-UMOD patient kidneys (A and B: case #1, C and D: case #3). * Indicates uromodulin expressing TALH. Note most of the atrophic tubules with thickened and lamellation of tubular basement membranes (yellow allows) are UMOD negative. Prominent inflammatory cells infiltrate around a sclerotic glomerulus (S) and atrophic tubules. N indicates normal glomerulus