Significance of kidney biopsy in autosomal dominant tubulointerstitial kidney disease-UMOD: is kidney biopsy truly nonspecific?

Table 4 The percentages and characteristics of tubules with visible UMOD accumulations in PAS staining

	total UMOD+ tubules	tubules with visible UMOD deposits					total	%^a
	total UMOD+ tubules	S-	S+	S++	L-	L++	total	%^a
#1	126	19	19	6	8	20	72	57.1%
#2	384	11	49	18	7	42	127	33.1%
#3	564	37	92	36	32	92	289	51.1%
#4	302	9	60	42	20	35	166	53.4%
#5	913	8	62	102	3	34	209	22.9%
#6	26	0	1	1	0	1	3	11.5%
#7	41	1	4	2	1	3	11	26.8%
#8	78	21	6	0	4	1	32	41.0%
#9	38	0	0	0	0	1	1	2.6%
#10	123	1	5	6	2	6	20	16.2%
#11	176	9	20	16	6	36	87	49.4%
sum	2733	116	318	229	83	270	1016	37.2%

S detected UMOD aggregation inside tubules was smaller than epithelial cell nuclei, L bigger than nuclei
++ halo around UMOD bigger than epithelial cell nuclei, + smaller than nuclei, − no halo
^a: numbers of tubules with visible UMOD accumulations in PAS staining/ total numbers of UMOD positive tubules in UMOD staining × 100

ISSN: 1471-2369