Variable | Controls | Cases | Group comparison | |||||||
---|---|---|---|---|---|---|---|---|---|---|
First data | Data < 8w later | n | p-value | Before intervention | After intervention | n | p-value | Parametric | Non-parametric | |
Controls vs Cases | Controls vs Cases | |||||||||
p-value | p-value | |||||||||
Calcium, mmol/L | 2.34 (0.41) | 2.35 (0.41) | 117 | 0.674 | 2.35 (0.17) | 2.35 (0.17) | 417 | 0.736 | 0.729 | 0.737 |
Phosphate, mmol/L | 1.60 (0.43) | 1.57 (0.41) | 117 | 0.548 | 1.65 (0.45) | 1.66 (0.49) | 413 | 0.873 | 0.193 | 0.214 |
Calcium x phosphate product | 3.7 (1.0) | 3.7 (1.0) | 117 | 0.197 | 3.9 (1.1) | 3.9 (1.2) | 433 | 0.158 | 0.197 | 0.261 |
Albumin, g/L | 36.9 (5.0) | 37.4 (5.4) | 118 | 0.107 | 36.5 (4.6) | 36.2 (4.6) | 407 | 0.052 | 0.308 | 0.432 |
Platelets, (×109) | 246 (88) | 250 (95) | 117 | 0.340 | 237 (76) | 241 (82) | 379 | 0.253 | 0.253 | 0.396 |
Hemoglobin, g/L | 114 (12) | 114 (12) | 118 | 0.531 | 114.7 (11.9) | 112.9 (12.3) | 427 | 0.001 | 0.261 | 0.23 |
PTH, ρmol/L | 33 (27) | 34 (25) | 100 | 0.740 | 27 (25) | 34 (106) | 349 | 0.253 | 0.022 | 0.009 |
Cholesterol mmol/L | 3.89 (0.79) | 3.78 (0.83) | 10 | 0.547 | 4.2 (1.5) | 3.8 (0.9) | 30 | 0.169 | 0.231 | 0.524 |
HbA1ca, mmol/mol | 49 (20) | 54 (20) | 17 | 0.039 | 58 (17) | 58 (16) | 101 | 0.448 | 0.033 | 0.037 |
Ferritin, μg/L | 449 (244) | 510 (489) | 104 | 0.133 | 467 (255) | 486 (251) | 313 | 0.095 | 0.701 | 0.871 |
Drug prescriptions: | ||||||||||
ESA, U/W | 4667 (3654) | 4673 (3701) | 78 | 0.975 | 7063 (387) | 6982 (382) | 333 | 0.153 | < 0.001 | < 0.001 |
Iron, mg/W | 43 (65) | 34 (35) | 72 | 0.211 | 59 (60) | 55 (44) | 234 | 0.257 | 0.073 | 0.004 |
LMWH, U/W | 11,949 (5062) | 12,270 (5581) | 74 | 0.282 | 14,225 (8022) | 14,537 (8174) | 227 | 0.183 | 0.064 | 0.028 |
HD conditions: | ||||||||||
Blood pump speed, ml/min | 307 (28) | 308 (20) | 61 | 0.708 | 288 (48) | 299 (46) | 185 | 0.001 | < 0.001 | < 0.001 |
Recirculation, % | 0.7 (4.5) | 0.2 (1.7) | 61 | 0.385 | 4.7 (11) | 0.7 (3.7) | 130 | < 0.001 | < 0.001 | < 0.001 |
Access flow, ml /min | 1105 (494) | 1090 (497) | 61 | 0.622 | 631 (446) | 866 (512) | 158 | < 0.001 | < 0.001 | < 0.001 |
HD, hours/W | 12.2 (2.7) | 12.0 (2.3) | 78 | 0.196 | 12.1 (2.4) | 12.3 (2.4) | 320 | 0.009 | 0.348 | 0.61 |
StKt/V | 2.16 (0.53) | 2.17 (0.58) | 72 | 0.831 | 1.88 (0.59) | 1.90 (0.59) | 257 | 0.237 | < 0.001 | < 0.001 |
Venous pressure | 137 (23) | 140 (29) | 62 | 0.492 | 133 (28) | 131 (31) | 121 | 0.409 | 0.263 | 0.295 |