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Table 4 Comparison (mean and SD) for Controls and for Cases. Data collected before vs after intervention (Cases) and for Controls (after 1 year free of AVF problems) and repeated within 8 weeks later for both groups. Also included are parametric and non-parametric comparisons between Controls first data and Cases before intervention

From: The association of erythropoietin-stimulating agents and increased risk for AV-fistula dysfunction in hemodialysis patients. A retrospective analysis

Variable

Controls

Cases

Group comparison

 

First data

Data < 8w later

n

p-value

Before

intervention

After intervention

n

p-value

Parametric

Non-parametric

Controls vs Cases

Controls vs Cases

p-value

p-value

Calcium, mmol/L

2.34 (0.41)

2.35 (0.41)

117

0.674

2.35 (0.17)

2.35 (0.17)

417

0.736

0.729

0.737

Phosphate, mmol/L

1.60 (0.43)

1.57 (0.41)

117

0.548

1.65 (0.45)

1.66 (0.49)

413

0.873

0.193

0.214

Calcium x phosphate product

3.7 (1.0)

3.7 (1.0)

117

0.197

3.9 (1.1)

3.9 (1.2)

433

0.158

0.197

0.261

Albumin, g/L

36.9 (5.0)

37.4 (5.4)

118

0.107

36.5 (4.6)

36.2 (4.6)

407

0.052

0.308

0.432

Platelets, (×109)

246 (88)

250 (95)

117

0.340

237 (76)

241 (82)

379

0.253

0.253

0.396

Hemoglobin, g/L

114 (12)

114 (12)

118

0.531

114.7 (11.9)

112.9 (12.3)

427

0.001

0.261

0.23

PTH, ρmol/L

33 (27)

34 (25)

100

0.740

27 (25)

34 (106)

349

0.253

0.022

0.009

Cholesterol mmol/L

3.89 (0.79)

3.78 (0.83)

10

0.547

4.2 (1.5)

3.8 (0.9)

30

0.169

0.231

0.524

HbA1ca, mmol/mol

49 (20)

54 (20)

17

0.039

58 (17)

58 (16)

101

0.448

0.033

0.037

Ferritin, μg/L

449 (244)

510 (489)

104

0.133

467 (255)

486 (251)

313

0.095

0.701

0.871

Drug prescriptions:

 ESA, U/W

4667 (3654)

4673 (3701)

78

0.975

7063 (387)

6982 (382)

333

0.153

< 0.001

< 0.001

 Iron, mg/W

43 (65)

34 (35)

72

0.211

59 (60)

55 (44)

234

0.257

0.073

0.004

 LMWH, U/W

11,949 (5062)

12,270 (5581)

74

0.282

14,225 (8022)

14,537 (8174)

227

0.183

0.064

0.028

HD conditions:

 Blood pump speed, ml/min

307 (28)

308 (20)

61

0.708

288 (48)

299 (46)

185

0.001

< 0.001

< 0.001

 Recirculation, %

0.7 (4.5)

0.2 (1.7)

61

0.385

4.7 (11)

0.7 (3.7)

130

< 0.001

< 0.001

< 0.001

 Access flow, ml /min

1105 (494)

1090 (497)

61

0.622

631 (446)

866 (512)

158

< 0.001

< 0.001

< 0.001

 HD, hours/W

12.2 (2.7)

12.0 (2.3)

78

0.196

12.1 (2.4)

12.3 (2.4)

320

0.009

0.348

0.61

 StKt/V

2.16 (0.53)

2.17 (0.58)

72

0.831

1.88 (0.59)

1.90 (0.59)

257

0.237

< 0.001

< 0.001

 Venous pressure

137 (23)

140 (29)

62

0.492

133 (28)

131 (31)

121

0.409

0.263

0.295

  1. *HbA1c results are given only for blood samples taken from patients with diabetes mellitus. PTH Parathyroid hormone, ESA Erythropoietin stimulating Agent, LMWH Low Molecular Weight Heparin, HD hemodialysis. Bold p-values indicate statistically significant values