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Table 3 Correlation of reflux nephropathy with different factors in patients with VUR (n = 46)

From: Prevalence of reflux nephropathy in Iranian children with solitary kidney: results of a multi-center study

Variable

With RN

Without RN

P-value*

Age (years) median (IQR)

4.50 (1.40 – 7.80)

3.00 (0.32 – 6.10)

0.301

Gender N (%)

 Male

12 (42.9)

16 (57.1)

0.064a

 Female

3 (16.7)

15 (83.3)

 

Birth weight (kg) median (IQR)

3.02 (2.75 – 3.18)

3.08 (2.89 – 3.25)

0.458

Birth height (cm) mean ± SD

48.36 ± 2.01

49.19 ± 1.60

0.248b

Basal Cr (mg/dl) median (IQR)

0.53 (0.45 – 0.65)

0.57 (0.50 – 0.68)

0.363

Current height (cm) median (IQR)

100.00 (82.50 – 113.50)

98.00 (86.25 – 119.25)

0.927

Current weight (kg) median (IQR)

17.33 (13.40 – 24.25)

15.90 (10.92 – 21.90)

0.429

eGFR (ml/min/1.73 m2) mean ± SD

74.11 ± 12.50

96.23 ± 33.98

0.182b

History of UTI N (%)

 Yes

7 (31.8)

15 (68.2)

0.466c

 No

7 (30.4)

16 (69.6)

 

 Unknown

1 (100.0)

0 (0.0)

 

VUR grade N (%)

 I-III

9 (34.6)

17 (65.4)

0.434c

 IV-V

5 (41.7)

7 (58.3)

 

 Unknown

1 (12.5)

7 (87.5)

 

Consanguineous parents N (%)

 Yes

0 (0.0)

9 (100.0)

0.063a

 No

9 (42.9)

12 (57.1)

 

 Unknown

6 (37.5)

10 (62.5)

 

Family history of solitary kidney N (%)

 Yes

0 (0.0)

1 (100.0)

0.202c

 No

0 (0.0)

5 (100.0)

 

 Unknown

15 (37.5)

25 (62.5)

 
  1. Abbreviations: N number, SD standard deviation, IQR interquartile range, RN reflux nephropathy, Cr creatinine, eGFR estimated glomerular filtration rate, UTI urinary tract infection, VUR vesicoureteral reflux
  2. *Analyzed by the Mann–Whitney test
  3. aAnalyzed by the chi-squared test
  4. bAnalyzed by the independent t-test
  5. cAnalyzed by the Fisher’s exact test