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Table 1 Characteristics of total MHD patients, MHD patients with and without diabetes

From: Association of plasma neutrophil gelatinase-associated lipocalin and thoracic aorta calcification in maintenance hemodialysis patients with and without diabetes

Characteristic

Total(N = 62)

With diabetes(N = 27)

Without diabetes(N = 35)

P

Male(0)/female(1)

30/32

14/13

16/19

0.798

Age (year)

58.10 ± 15.98

65.33 ± 13.17

52.51 ± 15.87

0.001

Smoking, (%)

21.0

25.9

17.1

0.297

Vintage (months)

29.27(8.65, 78.02)

19.28(3.78, 52.50)

40.27(16.16, 98.00)

0.007

Residual urine volume (ml/24 h)

0(0, 200)

100(0, 400)

0(0, 150)

0.123

SBP (mmHg)

155.05 ± 21.53

163.37 ± 17.68

148.63 ± 22.24

0.005

DBP (mmHg)

79.03 ± 16.13

68.48 ± 11.92

87.17 ± 14.32

< 0.001

Comorbid CHD, (%)

30.6

40.7

22.9

0.108

NGAL (ng/mL)

52.02(43.11, 422.30)

49.33(42.37,55.48)

56.78(44.37,674.13)

0.026

Klotho (pg/mL)

308.49(76.94, 877.32)

265.22(11.70, 1391.19)

319.96(138.46,608.23)

0.836

Ca (mmol/L)

2.29(2.17, 2.41)

2.21(2.12, 2.32)

2.35(2.27, 2.51)

0.001

P (mmol/L)

1.82(1.52, 2.26)

1.67(1.49, 1.91)

1.97(1.53, 2.53)

0.039

iPTH (pg/mL)

245.4 0(122.35, 864.75)

165.00(79.53, 274.80)

745.60(162.30, 1775.00)

< 0.001

ALP(U/L)

75.00(60.00, 146.25)

73.00(59.00, 91.00)

110.00(60.00, 353.00)

0.019

K (mmol/L)

5.02(4.44, 5.51)

4.86(4.45, 5.73)

5.10(4.40, 5.45)

0.943

HCO3−(mmol/L)

20.04 ± 3.25

20.21 ± 2.90

19.91 ± 3.53

0.716

BUN (mmol/L)

24.66 ± 6.09

23.50 ± 5.79

25.55 ± 6.24

0.191

Cr (μmol/L)

786.50(680.60, 922.00)

707.00(535.00, 752.00)

884.00(754.00, 1038.00)

< 0.001

Alb(g/L)

41.1(39.0, 43.75)

39.30(35.30, 42.10)

42.1(39.8, 44.60)

0.005

LDL (mmol/L)

2.04 ± 0.59

2.02 ± 0.67

2.06 ± 0.52

0.800

TG (mmol/L)

1.22(0.88,1.77)

1.12(0.88,1.75)

1.29(0.88,2.17)

0.247

SF (ng/mL)

155.10(80.13, 317.25)

135.87(83.65, 249.71)

197.64(78.19, 405.49)

0.089

Hb(g/L)

112.00(100.00, 121.25)

117.00(100.00, 124.00)

111.00(100.00, 119.00)

0.259

WBC(910^9/L)

6.06(4.55,7.37)

6.62(5.47, 7.98)

5.11(4.23, 7.29)

0.025

PLT(510^9/L)

189.50(160.00, 22D1.75)

203.00(145.00, 247.00)

184.00(164.00, 199.00)

0.338

Dialyzer membrane

    

 CTA, (%)

35.5

22.2

45.7

0.048

 PS, (%)

54.8

63.0

48.6

0.192

 PMMA, (%)

9.7

14.8

5.7

0.221

Calciums, (%)

79.0

66.7

88.6

0.037

Calcium free phosphorus binders carbonate)

 Sevelamer, (%)

25.8

3.7

42.9

< 0.001

 Lanthanum carbonate, (%)

16.1

18.5

14.3

0.735

Active vitamin D, (%)

29.0

7.4

45.7

0.001

Paricalcitol, (%)

8.1

3.7

11.4

0.376

Statins, (%)

16.1

33.3

2.9

0.002

  1. Continuous variables are expressed as mean ± standard deviation for normally distributed variables and as median (interquartile range) for variables with skewed distribution. Differences between patients with and without diabetes were assessed using the t test, Mann–Whitney U test or Chi-square analysis, as appropriate. Values with p < 0.05 were considered statistically significant and are indicated in bold
  2. MHD maintenance hemodialysis, SBP systolic blood pressure, DBP diastolic blood pressure, CHD Coronary heart disease, NGAL neutrophil gelatinase-associated lipocalin, Ca calcium, P phosphate, iPTH intact parathyroid hormone, ALP alkaline phosphatase, K potassium, HCO3- carbonate ion, BUN blood urea nitrogen, Cr creatinine, Alb albumin, LDL low density lipoprotein, TG triglyceride, SF serum ferritin, Hb hemoglobin, WBC white blood cells, PLT platelet, HD hemodialysis, HFD high-flux hemodialysis, HDF hemodiafiltration, CTA cellulose triacetate, PS polysulfone, PMMA polymethylmethacrylate