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  1. Precise renal histopathological diagnosis will guide therapy strategy in patients with lupus nephritis. Blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) has been applicable noninvasive tech...

    Authors: Huilan Shi, Junya Jia, Dong Li, Li Wei, Wenya Shang and Zhenfeng Zheng
    Citation: BMC Nephrology 2018 19:33
  2. Association between high body mass index (BMI) and survival benefit is confounded by comorbid conditions such as nutritional status and inflammation. Patients with acute kidney injury (AKI), particularly those...

    Authors: Hyoungnae Kim, Hyunwook Kim, Misol Lee, Min-Uk Cha, Ki Heon Nam, Seong Yeong An, Su-Young Jung, Jong Hyun Jhee, Seohyun Park, Hae-Ryong Yun, Youn Kyung Kee, Hyung Jung Oh, Jung Tak Park, Tae Ik Chang, Tae-Hyun Yoo, Shin-Wook Kang…
    Citation: BMC Nephrology 2018 19:32
  3. The prognostic effect of gender on immunoglobulin A nephropathy (IgAN) is not clear. We explored gender-related differences in clinicopathological features and renal outcomes in IgAN.

    Authors: Wei Deng, Xiaojun Tan, Qian Zhou, Zhen Ai, Wenting Liu, Wei Chen, Xueqing Yu and Qiongqiong Yang
    Citation: BMC Nephrology 2018 19:31
  4. It remains unclear whether genetic factors may explain the reported variation in the levels of biochemical markers of chronic kidney disease mineral and bone disorders (CKD- MBD) across ethnic groups. Therefor...

    Authors: Bala Waziri, Therese Dix-Peek, Caroline Dickens, Raquel Duarte and Saraladevi Naicker
    Citation: BMC Nephrology 2018 19:30
  5. The MAPK-organizer 1 (MORG1) play a scaffold function in the MAPK and/or the PHD3 signalling paths. Recently, we reported that MORG1+/− mice are protected from renal injury induced by systemic hypoxia and acute r...

    Authors: Tzvetanka Bondeva, Claudia Schindler, Katrin Schindler and Gunter Wolf
    Citation: BMC Nephrology 2018 19:29
  6. Chronic kidney disease (CKD) is increasing worldwide and early education to improve adherence to self-management is a key strategy to slow CKD progression. The use of the internet and mobile phone technologies...

    Authors: Ann Bonner, Kerri Gillespie, Katrina L. Campbell, Katina Corones-Watkins, Bronwyn Hayes, Barbara Harvie, Jaimon T. Kelly and Kathryn Havas
    Citation: BMC Nephrology 2018 19:28
  7. The association of increased cancer risk with glomerulonephritis (GN) is well known, but controversy exists concerning which types of GN are involved, and the size of the association. A national registry surve...

    Authors: James Goya Heaf, Alastair Hansen and Gunnar Hellmund Laier
    Citation: BMC Nephrology 2018 19:27
  8. It has been reported that mutations in arginine vasopressin type 2 receptor (AVPR2) cause congenital X-linked nephrogenic diabetes insipidus (NDI). However, only a few cases of AVPR2 deletion have been documented...

    Authors: Ying Bai, Yibing Chen and Xiangdong Kong
    Citation: BMC Nephrology 2018 19:26
  9. Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epide...

    Authors: William R. Cooke, Ulla K. Hemmilä, Alison L. Craik, Chimwemwe J. Mandula, Priscilla Mvula, Ausbert Msusa, Gavin Dreyer and Rhys Evans
    Citation: BMC Nephrology 2018 19:25
  10. Changes in mineral metabolism and bone structure develop early in the course of chronic kidney disease and at end-stage are associated with increased risk of fragility fractures. The disruption of phosphorus h...

    Authors: Nikita M. Bajwa, Cheryl P. Sanchez, Richard C. Lindsey, Heather Watt and Subburaman Mohan
    Citation: BMC Nephrology 2018 19:24
  11. Leigh syndrome (LS) is a rare neurodegenerative mitochondrial disorder which typically presents in childhood but has a varied clinical course. Renal involvement such as proximal tubulopathy in patients with mi...

    Authors: Kathryn Ducharlet, Dominic Thyagarajan, Francesco Ierino, Lawrence P. McMahon and Darren Lee
    Citation: BMC Nephrology 2018 19:23
  12. Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correct...

    Authors: Vivek Kumar, Ashok Kumar Yadav, Yoshinari Yasuda, Masaru Horio, Vinod Kumar, Nancy Sahni, Krishan L. Gupta, Seiichi Matsuo, Harbir Singh Kohli and Vivekanand Jha
    Citation: BMC Nephrology 2018 19:22
  13. Leptospirosis is a rare infectious disease especially in Western Countries. Renal involvement is a recognised complication of leptospirosis but leptospirosis-associated haemolytic uraemic syndrome is extremely...

    Authors: Vasantha Muthu Muthuppalaniappan, Ravindra Rajakariar and Mark John Blunden
    Citation: BMC Nephrology 2018 19:20
  14. Epoetin beta pegol (continuous erythropoietin receptor activator; C.E.R.A.) is currently widely used for the treatment of anemia associated with chronic kidney disease (CKD). Therapeutic control of anemia is a...

    Authors: Ken Aizawa, Ryohei Kawasaki, Yoshihito Tashiro, Yasushi Shimonaka and Michinori Hirata
    Citation: BMC Nephrology 2018 19:19
  15. Cellulitis is an unusual presentation of disseminated cryptococcosis, a serious infection seen predominantly in immunocompromised hosts. Disseminated cryptococcosis carries significant morbidity for transplant...

    Authors: Katrina Chakradeo, Y. Y. Paul Chia, Cheng Liu, David W. Mudge and Janath De Silva
    Citation: BMC Nephrology 2018 19:18
  16. Our aim was to evaluate lipid trafficking and inflammatory response of macrophages exposed to lipoproteins from subjects with moderate to severe chronic kidney disease (CKD), and to investigate the potential b...

    Authors: Ryohei Kaseda, Yohei Tsuchida, Hai-Chun Yang, Patricia G. Yancey, Jianyong Zhong, Huan Tao, Aihua Bian, Agnes B. Fogo, Mac Rae F. Linton, Sergio Fazio, Talat Alp Ikizler and Valentina Kon
    Citation: BMC Nephrology 2018 19:17
  17. For patients unable to receive heparin anticoagulation during haemodialysis, saline flushes to reduce circuit clotting are often the norm. Regional citrate anticoagulation (RCA) although effective is not used ...

    Authors: Eng Kuang Lim, Ying-ying T Seow, Shun E Chen, Gao Yang, Min Er Liaw and Shimi Isaac
    Citation: BMC Nephrology 2018 19:16
  18. Most estimates for End Stage Kidney Disease (ESKD) prevalence and incidence are based on renal replacement therapy (RRT) registers. However, not all people with ESKD will commence RRT and estimates based only ...

    Authors: Lin Li, Steven Guthridge, Shu Qin Li, Yuejen Zhao, Paul Lawton and Alan Cass
    Citation: BMC Nephrology 2018 19:15
  19. Recently there has been a progressive loss of specialty related skills for nephrologists. Among the skills we find the kidney biopsy that has a central role in diagnosis of renal parenchymal disease. One of th...

    Authors: Vittoria Esposito, Giulia Mazzon, Paola Baiardi, Massimo Torreggiani, Luca Semeraro, Davide Catucci, Marco Colucci, Alice Mariotto, Fabrizio Grosjean, Giacomo Bovio and Ciro Esposito
    Citation: BMC Nephrology 2018 19:14
  20. The Reducing Disparities in Access to kidNey Transplantation Community Study (RaDIANT) was an End-Stage Renal Disease (ESRD) Network 6-developed, dialysis facility-level randomized trial testing the effectiven...

    Authors: Reem E. Hamoda, Jennifer C. Gander, Laura J. McPherson, Kimberly J. Arriola, Loren Cobb, Stephen O. Pastan, Laura Plantinga, Teri Browne, Erica Hartmann, Laura Mulloy, Carlos Zayas, Jenna Krisher and Rachel E. Patzer
    Citation: BMC Nephrology 2018 19:13
  21. Therapeutic plasma exchange (TPE) is increasingly used throughout the world. Although the procedure itself is fairly standardized, it is yet unknown how the underlying disease entities influence the key coordi...

    Authors: Julius J. Schmidt, Firas Asper, Gunilla Einecke, Gabriele Eden, Carsten Hafer and Jan T. Kielstein
    Citation: BMC Nephrology 2018 19:12
  22. For older adults receiving dialysis, health-related quality of life is not often considered in prognostication of death or future hospitalizations. To determine if routine health-related quality of life measur...

    Authors: Rasheeda K. Hall, Alison Luciano, Carl Pieper and Cathleen S. Colón-Emeric
    Citation: BMC Nephrology 2018 19:11
  23. Agricultural workers especially in sugarcane plantations have a high risk of chronic kidney disease (CKD). Little is known about CKD among sugarcane plantation workers in Cameroon. This study sought to evaluat...

    Authors: Martin E. Ekiti, Jean-Berthelot Zambo, Felix K. Assah, Valirie N. Agbor, Krystel Kekay and Gloria Ashuntantang
    Citation: BMC Nephrology 2018 19:10
  24. Thrombotic microangiopathy (TMA) secondary to gemcitabine therapy (GiTMA) is a very rare pathology that carries a poor prognosis, with nearly half of the cases progressing to end stage renal disease. GiTMA is ...

    Authors: Vinod Krishnappa, Mohit Gupta, Haikoo Shah, Abhijit Das, Natthavat Tanphaichitr, Robert Novak and Rupesh Raina
    Citation: BMC Nephrology 2018 19:9
  25. The Fried frailty phenotype, a measure of physiologic reserve defined by 5 components (exhaustion, unintentional weight loss, low physical activity, slow walking speed, and poor grip strength), is associated w...

    Authors: Sarah Van Pilsum Rasmussen, Jonathan Konel, Fatima Warsame, Hao Ying, Brian Buta, Christine Haugen, Elizabeth King, Sandra DiBrito, Ravi Varadhan, Leocadio Rodríguez-Mañas, Jeremy D. Walston, Dorry L. Segev and Mara A. McAdams-DeMarco
    Citation: BMC Nephrology 2018 19:8
  26. C3 glomerulopathy (C3G) is a rare, but severe glomerular disease with grim prognosis. The complex pathogenesis is just unfolding, and involves acquired as well as inherited dysregulation of the alternative pat...

    Authors: Thomas Welte, Frederic Arnold, Julia Kappes, Maximilian Seidl, Karsten Häffner, Carsten Bergmann, Gerd Walz and Elke Neumann-Haefelin
    Citation: BMC Nephrology 2018 19:7
  27. Despite the development of biomarkers and noninvasive imaging tools, biopsy remains the only method for correctly diagnosing patients with unexplained hematuria, proteinuria and renal failure. Renal biopsy has...

    Authors: Hsien-Fu Chiu, Hung-chun Chen, Kuo-Cheng Lu and Kuo-Hsiung Shu
    Citation: BMC Nephrology 2018 19:6
  28. Racial/ethnic, gender, and age disparities in access to renal transplantation among end-stage renal disease (ESRD) patients have been well documented, but few studies have explored health care staff attitudes ...

    Authors: Kristie J. Lipford, Laura McPherson, Reem Hamoda, Teri Browne, Jennifer C. Gander, Stephen O. Pastan and Rachel E. Patzer
    Citation: BMC Nephrology 2018 19:5
  29. There is conflicting evidence of benefit versus harm for warfarin anticoagulation in hemodialysis patients with atrial fibrillation. This equipoise may be explained by suboptimal Time in Therapeutic Range (TTR...

    Authors: Hamad Bahbahani, Ahmed AlTurki, Ahmed Dawas and Mark L. Lipman
    Citation: BMC Nephrology 2018 19:4
  30. Kidney transplantation following uncontrolled donation after circulatory death (uDCD) presents a high risk of delayed graft function due to prolonged warm ischemia time. In order to minimise the effects of isc...

    Authors: Claire Delsuc, Alexandre Faure, Julien Berthiller, Didier Dorez, Xavier Matillon, Vannary Meas-Yedid, Bernard Floccard, Guillaume Marcotte, Vanessa Labeye, Maud Rabeyrin, Ricardo Codas, Cécile Chauvet, Philip Robinson, Emmanuel Morelon, Lionel Badet, William Hanf…
    Citation: BMC Nephrology 2018 19:3
  31. Despite pre-kidney-transplant cardiovascular (CV) assessment being routine care to minimise perioperative risk, the utility of such assessment is not well established. The study reviewed the evaluation and out...

    Authors: Robin Ramphul, Maria Fernandez, Sam Firoozi, Juan C. Kaski, Rajan Sharma and Debasish Banerjee
    Citation: BMC Nephrology 2018 19:2
  32. Membranes with increasing pore size are introduced to enhance removal of large uremic toxins with regular hemodialysis. These membranes might theoretically have higher permeability for bacterial degradation pr...

    Authors: Eva Schepers, Griet Glorieux, Sunny Eloot, Michael Hulko, Adriana Boschetti-de-Fierro, Werner Beck, Bernd Krause and Wim Van Biesen
    Citation: BMC Nephrology 2018 19:1
  33. High-dose methylprednisolone pulses were one of the main treatments for anti-neutrophil cytoplasmic autoantibody (ANCA) associated vasculitides (AAV) but had obvious side effects. We aimed to know the impact o...

    Authors: Yanhong Ma, Fei Han, Liangliang Chen, Hongya Wang, Haidongqing Han, Binfeng Yu, Ying Xu and Jianghua Chen
    Citation: BMC Nephrology 2017 18:381
  34. We aimed to describe clinical characteristics of patients with community-acquired acute kidney injury (CA-AKI), the effectiveness of initial management of CA-AKI, its prognosis and the impact of medication on ...

    Authors: Fabien Stucker, Belen Ponte, Victoria De la Fuente, Cyrielle Alves, Olivier Rutschmann, Sebastian Carballo, Nicolas Vuilleumier, Pierre-Yves Martin, Thomas Perneger and Patrick Saudan
    Citation: BMC Nephrology 2017 18:380
  35. The United States is faced with an unprecedented epidemic of drug abuse. Every year thousands of Americans visit the emergency departments all over the country with illicit drug related complaints. These drugs...

    Authors: Kanaan Mansoor, Murad Kheetan, Saba Shahnawaz, Anna P. Shapiro, Eva Patton-Tackett, Larry Dial, Gary Rankin, Prasanna Santhanam, Antonios H. Tzamaloukas, Tibor Nadasdy, Joseph I. Shapiro and Zeid J. Khitan
    Citation: BMC Nephrology 2017 18:379
  36. In ANCA-associated vasculitis the acute phase of the disease is often preceded by prodromal symptoms. The aim of the present study was to analyze the relation between the duration of the prodromal phase and re...

    Authors: Eline Houben, Stefanie L. Groenland, Joost W. van der Heijden, Alexandre E. Voskuyl, Hiëronymus J. Doodeman and Erik L. Penne
    Citation: BMC Nephrology 2017 18:378
  37. Amyloid A amyloidosis is one of the most common forms of amyloidosis. It is secondary to rheumatoid arthritis, which is difficult to manage and has a poor prognosis. We present a patient with rheumatoid arthri...

    Authors: Akira Yamagata, Takahiro Uchida, Yuji Yamada, Takashi Nakanishi, Kazue Nagai, Toshihiko Imakiire, Naoki Oshima and Hiroo Kumagai
    Citation: BMC Nephrology 2017 18:377
  38. To evaluate the incidence of Acute Kidney Injury (AKI) during therapeutic hypothermia (TH) and rewarming in comatose patients resuscitated from Cardiac Arrest (CA).

    Authors: Silvia De Rosa, Massimo De Cal, Michael Joannidis, Gianluca Villa, Jose Luis Salas Pacheco, Grazia Maria Virzì, Sara Samoni, Fiorella D’ippoliti, Stefano Marcante, Federico Visconti, Antonella Lampariello, Marina Zannato, Silvio Marafon, Raffaele Bonato and Claudio Ronco
    Citation: BMC Nephrology 2017 18:376
  39. Patients with CKD are at increased risk of potentially preventable hospital acquired complications (HACs). Understanding the economic consequences of preventable HACs, may define the scope and investment of in...

    Authors: Babak Bohlouli, Terri Jackson, Marcello Tonelli, Brenda Hemmelgarn and Scott Klarenbach
    Citation: BMC Nephrology 2017 18:375
  40. High fat diets are implicated in the pathogenesis of metabolic syndrome, obesity and renal disease. Previous studies have revealed that high fat diets promote vascular calcification in uremic rats. Moreover, v...

    Authors: Rafael Rios, Ana I. Raya, Carmen Pineda, Mariano Rodriguez, Ignacio Lopez and Escolastico Aguilera-Tejero
    Citation: BMC Nephrology 2017 18:374
  41. Evaluation of patient’s dry weight remains challenging in chronic hemodialysis (HD) especially in children. Inferior Vena Cava (IVC) measurement was reported useful to assess fluid overload both in adults and ...

    Authors: Xavier Torterüe, Laurène Dehoux, Marie-Alice Macher, Olivier Niel, Thérésa Kwon, Georges Deschênes and Julien Hogan
    Citation: BMC Nephrology 2017 18:373
  42. Aim of our study is to describe, in people with CKD, the demographic and clinical characteristics and outcomes with increasing age. The prevalence of CKD in Western populations, where longevity is the norm, is...

    Authors: Usman Mahmood, Helen G. Healy, Adrian Kark, Anne Cameron, Zaimin Wang, Rajitha Abeysekera and Wendy E. Hoy
    Citation: BMC Nephrology 2017 18:372
  43. Though on-line intermittent hemodiafiltration (OL-IHDF) is a routine therapy for chronic dialysis patients, it is not yet widespread used in critically ill patients. This study was undergone to evaluate effici...

    Authors: Kada Klouche, Laurent Amigues, Marion Morena, Vincent Brunot, Anne Marie Dupuy, Audrey Jaussent, Marie Christine Picot, Noémie Besnard, Delphine Daubin and Jean Paul Cristol
    Citation: BMC Nephrology 2017 18:371
  44. Aldosterone is elevated in chronic kidney disease (CKD) and may be involved in hypertension. Surprisingly, the determinants of the plasma aldosterone concentration (PAC) and its role in hypertension are not we...

    Authors: Christina M. Gant, Gozewijn D. Laverman, Liffert Vogt, Maartje C. J. Slagman, Hiddo J. L. Heerspink, Femke Waanders, Marc H. Hemmelder and Gerjan Navis
    Citation: BMC Nephrology 2017 18:370
  45. Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (C...

    Authors: Geoffrey Omuse, Daniel Maina, Jane Mwangi, Caroline Wambua, Alice Kanyua, Elizabeth Kagotho, Angela Amayo, Peter Ojwang and Rajiv Erasmus
    Citation: BMC Nephrology 2017 18:369
  46. The most commonly used glomerular filtration rate estimating equations for drug dosing are Cockcroft-Gault (CG), Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration ...

    Authors: Hunduma Dinsa, Teshome Nedi and Alemseged Beyene Berha
    Citation: BMC Nephrology 2017 18:368
  47. Systemic inflammation has been implicated in several chronic diseases. GlycA is a new nuclear mass resonance (NMR) spectroscopy-derived biomarker of systemic inflammation that reflects protein glycosylation. W...

    Authors: Silvia M. Titan, Roberto Pecoits-Filho, Sandhi M. Barreto, Antônio Alberto Lopes, Isabela J. Bensenor and Paulo A. Lotufo
    Citation: BMC Nephrology 2017 18:367
  48. Chronic kidney disease patients have an increased prevalence of subclinical cerebrovascular diseases. Dialysis patients have severe vascular diseases burden. The cerebral small vessel diseases (CSVD) are diffi...

    Authors: Ke Zheng, Haiyun Wang, Bo Hou, Hui You, Jing Yuan, Kai Luo, Limeng Chen, Mingxi Li, Qun Xu, Yicheng Zhu, Liying Cui, Sagar Uday Nigwekar, Feng Feng and Xuemei Li
    Citation: BMC Nephrology 2017 18:366
  49. Percutaneous renal biopsy (PRB) is an important technique providing relevant information to guide diagnosis and treatment in renal disease. As an invasive procedure it has complications. Most studies up to dat...

    Authors: R. Haridian Sosa-Barrios, Victor Burguera, Nuria Rodriguez-Mendiola, Cristina Galeano, Sandra Elias, Gloria Ruiz-Roso, Sara Jimenez-Alvaro, Fernando Liaño and Maite Rivera-Gorrin
    Citation: BMC Nephrology 2017 18:365

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