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  1. Sclerostin is a Wnt pathway antagonist regulating osteoblast activity and bone turnover. Here, we assessed the potential association of sclerostin with the development of coronary artery (CAC) and aortic valve...

    Authors: Vincent M Brandenburg, Rafael Kramann, Ralf Koos, Thilo Krüger, Leon Schurgers, Georg Mühlenbruch, Sinah Hübner, Ulrich Gladziwa, Christiane Drechsler and Markus Ketteler
    Citation: BMC Nephrology 2013 14:219
  2. Blood transfusions have the potential to improve graft survival, induce sensitization, and transmit infections. Current clinical practice is to minimize transfusions in renal transplantation candidates, but it...

    Authors: Juan C Scornik, Jonathan S Bromberg, Douglas J Norman, Mayank Bhanderi, Matthew Gitlin and Jeffrey Petersen
    Citation: BMC Nephrology 2013 14:217
  3. The majority of bicarbonate based dialysis fluids are acidified with acetate. Citrate, a well known anticoagulant and antioxidant, has been suggested as a biocompatible alternative. The objective of this study...

    Authors: Gunilla Grundström, Anders Christensson, Maria Alquist, Lars-Göran Nilsson and Mårten Segelmark
    Citation: BMC Nephrology 2013 14:216
  4. Chronic kidney disease (CKD) is one of the most serious public health problems. The increasing prevalence of CKD in developed and developing countries has led to a global epidemic. The hypothesis proposed is t...

    Authors: Israel dos Reis Santos, Aline Roberta Danaga, Isabella de Carvalho Aguiar, Ezequiel Fernandes Oliveira, Ismael Souza Dias, Jessica Julioti Urbano, Aline Almeida Martins, Leonardo Macario Ferraz, Nina Teixeira Fonsêca, Virgilio Fernandes, Vinicius Alves Thomaz Fernandes, Viviane Cristina Delgado Lopes, Fernando Sérgio Studart Leitão Filho, Sérgio Roberto Nacif, Paulo de Tarso Camillo de Carvalho, Luciana Maria Malosá Sampaio…
    Citation: BMC Nephrology 2013 14:215
  5. To investigate gene expression of podocyte-specific proteins in urine of diabetes and prediabetes subjects and the association of these proteins with albuminuria.

    Authors: Jonathan Fraportti do Nascimento, Luis H Canani, Fernando Gerchman, Patricia G Rodrigues, Gabriel Joelsons, Mariane dos Santos, Sane Pereira and Francisco V Veronese
    Citation: BMC Nephrology 2013 14:214
  6. Stress-induced cardiomyopathy (sCMP) is characterized by transient wall-motion abnormalities involving the left ventricular apex and mid-ventricle that are precipitated by emotional or physical stress. As the ...

    Authors: Min Ji Shin, Harin Rhee, Il Young Kim, Byeong Yun Yang, Sang Heon Song, Dong Won Lee, Soo Bong Lee, Ihm Soo Kwak, Jung Hyun Choi and Eun Young Seong
    Citation: BMC Nephrology 2013 14:213
  7. Peripheral artery disease (PAD) represents atherosclerotic disease and is a risk factor for death in peritoneal dialysis (PD) patients, who tend to show an atherogenic lipid profile. In this study, we investig...

    Authors: Eiichiro Kanda, Masumi Ai, Mitsuyo Okazaki, Yoshitaka Maeda, Sei Sasaki and Masayuki Yoshida
    Citation: BMC Nephrology 2013 14:212
  8. Chronic exposure to low cadmium (Cd) levels produces urinary excretion of low molecular weight proteins, which is considered the critical effect of Cd exposure. However, the mechanisms involved in Cd-induced p...

    Authors: Mitzi Paola Santoyo-Sánchez, José Pedraza-Chaverri, Eduardo Molina-Jijón, Laura Arreola-Mendoza, Rafael Rodríguez-Muñoz and Olivier Christophe Barbier
    Citation: BMC Nephrology 2013 14:211
  9. Renal biopsies provide important diagnostic and prognostic information in ANCA associated glomerulonephritis. A new classification for prognostication of pauci-immune glomerulonephritis (GN) based on four cate...

    Authors: Carla L Ellis, Rebecca L Manno, John P Havill, Lorraine C Racusen and Duvuru Geetha
    Citation: BMC Nephrology 2013 14:210
  10. Kidney injuries provoke considerable adjustment of renal physiology, metabolism, and architecture to nephron loss. Despite remarkable regenerative capacity of the renal tissue, these adaptations often lead to ...

    Authors: Larisa V Fedorova, Anita Tamirisa, David J Kennedy, Steven T Haller, Georgy Budnyy, Joseph I Shapiro and Deepak Malhotra
    Citation: BMC Nephrology 2013 14:209
  11. Despite the evidence that phosphate binder (PB) is associated with improved outcomes many hemodialysis patients do not adhere to prescribed PB regimen. Therefore, barriers to PB adherence should be identified ...

    Authors: Maria Tereza Silveira Martins, Luciana Ferreira Silva, Angiolina Kraychete, Dandara Reis, Lidiane Dias, Gabriel Schnitman, Lívia Oliveira, Gildete Barreto Lopes and Antonio Alberto Lopes
    Citation: BMC Nephrology 2013 14:208
  12. Polyomavirus BK nephropathy (PyVAN) remains an important cause of early graft dysfunction and graft loss in kidney transplantation.

    Authors: Johannes Jacobi, Antonina Prignitz, Maike Büttner, Klaus Korn, Alexander Weidemann, Karl F Hilgers, Katharina Heller, Joachim Velden, Antje Knöll, Bernd Wullich, Christoph May, Kai-Uwe Eckardt and Kerstin U Amann
    Citation: BMC Nephrology 2013 14:207
  13. Vitamin D insufficiency is associated with proteinuria and could be a risk factor for end-stage renal disease (ESRD). However, few studies have examined the significance of vitamin D insufficiency as a contrib...

    Authors: Bancha Satirapoj, Pokkrong Limwannata, Amnart Chaiprasert, Ouppatham Supasyndh and Panbuppa Choovichian
    Citation: BMC Nephrology 2013 14:206
  14. Phosphate binders’ constituents have alkalotic or acidotic properties and may contribute to acid base balance in haemodialysis patients. This study aimed to investigate the differential effects of phosphate bi...

    Authors: Zaw Thet, Aung Ko WIN, Eugenie Pedagogos, Jennifer Beavis, Sandra Crikis and Craig Nelson
    Citation: BMC Nephrology 2013 14:205
  15. Exercise during hemodialysis treatments improves physical function, markers of cardiovascular disease and quality of life. However, exercise programs are not a part of standard therapy in the vast majority of ...

    Authors: Paul N Bennett, Robin M Daly, Steve F Fraser, Terry Haines, Robert Barnard, Cherene Ockerby and Bridie Kent
    Citation: BMC Nephrology 2013 14:204
  16. Post-transplantation encapsulating peritoneal sclerosis (EPS) causing bowel obstruction has been identified as a serious complication after kidney transplantation in patients previously treated with peritoneal...

    Authors: Sayed Meelad Habib, Frank Johan Marinus Frederik Dor, Mario Richard Korte, Sander Martijn Hagen and Michiel Gerardus Henricus Betjes
    Citation: BMC Nephrology 2013 14:203
  17. The renal distal nephron plays an important role in the maintenance of sodium balance, extra cellular volume and blood pressure. The degree of water transport, via aquaporin2 water channels (AQP2), and sodium ...

    Authors: Janni M Jensen, Frank H Mose, Jesper N Bech, Soren Nielsen and Erling B Pedersen
    Citation: BMC Nephrology 2013 14:202
  18. Among African-Americans adults, arterial hypertension is both more prevalent and associated with more complications than among white adults. Hypertension is also epidemic among black adults in sub-Saharan Afri...

    Authors: Robert N Peck, Luke R Smart, Rita Beier, Anthony C Liwa, Heiner Grosskurth, Daniel W Fitzgerald and Bernhard MW Schmidt
    Citation: BMC Nephrology 2013 14:201
  19. Responsiveness to erythropoiesis-stimulating agents (ESAs) varies widely among dialysis patients. ESA resistance has been associated with mortality in hemodialysis (HD) patients, but in peritoneal dialysis (PD...

    Authors: Marit M Suttorp, Tiny Hoekstra, Joris I Rotmans, Ilka Ott, Moshe Mittelman, Raymond T Krediet and Friedo W Dekker
    Citation: BMC Nephrology 2013 14:200
  20. Vitamin D insufficiency correlates with mortality risk among patients with chronic kidney disease (CKD). The survival benefits of active vitamin D treatment have been assessed in patients with CKD not requirin...

    Authors: Zhenfeng Zheng, Huilan Shi, Junya Jia, Dong Li and Shan Lin
    Citation: BMC Nephrology 2013 14:199
  21. Chronic kidney disease (CKD) is a known risk factor for cardiovascular events and all-cause mortality. We investigate the relationship between CKD stage, proteinuria, hypertension and these adverse outcomes in...

    Authors: Andrew P McGovern, Benjamin Rusholme, Simon Jones, Jeremy N van Vlymen, Harshana Liyanage, Hugh Gallagher, Charles RV Tomson, Kamlesh Khunti, Kevin Harris and Simon de Lusignan
    Citation: BMC Nephrology 2013 14:198
  22. Ten years on from the National Institute of Health and Clinical Excellence’ technology appraisal guideline on haemodialysis in 2002; the clinical community is yet to rise to the challenge of providing home hae...

    Authors: Anuradha Jayanti, Alison J Wearden, Julie Morris, Paul Brenchley, Inger Abma, Steffen Bayer, James Barlow and Sandip Mitra
    Citation: BMC Nephrology 2013 14:197
  23. HUPRA syndrome is a rare mitochondrial disease characterized by hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis. This syndrome was previously described in three patients with a ho...

    Authors: Henry Rivera, Elena Martín-Hernández, Aitor Delmiro, María Teresa García-Silva, Pilar Quijada-Fraile, Rafael Muley, Joaquín Arenas, Miguel A Martín and Francisco Martínez-Azorín
    Citation: BMC Nephrology 2013 14:195
  24. Restless Legs Syndrome is very common in hemodialysis patients however there are no comparative studies assessing the effectiveness of a non-pharmacological treatment to a classical treatment on parameters rel...

    Authors: Christoforos D Giannaki, Giorgos K Sakkas, Christina Karatzaferi, Georgios M Hadjigeorgiou, Eleftherios Lavdas, Theodoros Kyriakides, Yiannis Koutedakis and Ioannis Stefanidis
    Citation: BMC Nephrology 2013 14:194
  25. Enhanced external counterpulsation (EECP) enhances coronary perfusion and reduces left ventricular afterload. However, the role of EECP on renal function in cardiac patients is unknown. Our aim was to assess r...

    Authors: Prajej Ruangkanchanasetr, Nithi Mahanonda, Ongkarn Raungratanaamporn, Piyanuj Ruckpanich, Chagriya Kitiyakara, Amnart Chaiprasert, Surawat Adirekkiat, Dollapas Punpanich, Somlak Vanavanan, Anchalee Chittamma and Thanom Supaporn
    Citation: BMC Nephrology 2013 14:193
  26. There is a paucity of information about the views of dialysis nurses towards dialysis modality selection, yet nurses often have the most direct contact time with patients. We conducted a survey to better under...

    Authors: Karthik K Tennankore, Jay Hingwala, Diane Watson, Joanne M Bargman and Christopher T Chan
    Citation: BMC Nephrology 2013 14:192
  27. In the general population, reported levels of oxidative stress and antioxidant potential seem to vary. The aim of this study was to investigate the levels of oxidant status markers in relation to estimated glo...

    Authors: Yuko Ishizaka, Minoru Yamakado, Akiko Toda, Mizuki Tani and Nobukazu Ishizaka
    Citation: BMC Nephrology 2013 14:191
  28. Polycystic kidney diseases (PKD) are a group of monogenic disorders that are inherited dominantly (autosomal dominant PKD; ADPKD) or recessively, including, autosomal recessive PKD (ARPKD). A number of recessi...

    Authors: Reza Vazifehmand, Sandro Rossetti, Sassan Saber, Hamid Reza Khorram Khorshid and Peter C Harris
    Citation: BMC Nephrology 2013 14:190
  29. Haemodialysis patients have an increased prevalence of hypertension and risk of cardiovascular mortality and stroke. Higher dialysate calcium concentrations have been reported to cause both an acute and chroni...

    Authors: Evangelia Charitaki and Andrew Davenport
    Citation: BMC Nephrology 2013 14:189
  30. Hepatitis C virus (HCV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide, but the role of HCV infection in causing CKD remains uncertain. This cohort study aimed to expl...

    Authors: Yi-Chun Chen, Wen-Yen Chiou, Shih-Kai Hung, Yu-Chieh Su and Shang-Jyh Hwang
    Citation: BMC Nephrology 2013 14:187
  31. Some 7-10% of patients on replacement renal therapy (RRT) are receiving it because of autosomal dominant polycystic kidney disease (ADPKD). The age at initiation of RRT is expected to increase over time.

    Authors: Víctor Martínez, Jordi Comas, Emma Arcos, Joan Manel Díaz, Salomé Muray, Juan Cabezuelo, José Ballarín, Elisabet Ars and Roser Torra
    Citation: BMC Nephrology 2013 14:186
  32. The aim of this study was to evaluate whether a high baseline level of high-sensitivity C-reactive protein (hs-CRP) or changes in the level predicts the risk of peritonitis in patients on continuous ambulatory...

    Authors: Yu-Jen Su, Shang-Chih Liao, Ben-Chung Cheng, Jyh-Chang Hwang and Jin-Bor Chen
    Citation: BMC Nephrology 2013 14:185
  33. Chronic kidney disease (CKD) involves a progressive, irreversible loss of kidney function. While early-stage CKD patients may show changes in pulmonary function and lowered exercise tolerance, the role of the ...

    Authors: Ruiter de Souza Faria, Natália Fernandes, Júlio César Moraes Lovisi, Maycon de Moura Reboredo, Murilo Sérgio de Moura Marta, Bruno do Valle Pinheiro and Marcus Gomes Bastos
    Citation: BMC Nephrology 2013 14:184
  34. The number of adults with diabetes mellitus is increasing worldwide, particularly in Asia and Africa. In sub-Saharan Africa, renal complications of diabetes may go unrecognized due to limited diagnostic resour...

    Authors: Mubarakali N Janmohamed, Samuel E Kalluvya, Andreas Mueller, Rodrick Kabangila, Luke R Smart, Jennifer A Downs and Robert N Peck
    Citation: BMC Nephrology 2013 14:183
  35. Early referral and management of high-risk chronic kidney disease may prevent or delay the need for dialysis. Automatic eGFR reporting has increased demand for out-patient nephrology consultations and in some ...

    Authors: Michael E Schachter, Alexandra Romann, Ognjenka Djurdev, Adeera Levin and Monica Beaulieu
    Citation: BMC Nephrology 2013 14:182
  36. Accurate and precise estimates of glomerular filtration rate (GFR) are essential for clinical assessments, and many methods of estimation are available. We developed a radial basis function (RBF) network and a...

    Authors: Xun Liu, Yan-Ru Chen, Ning-shan Li, Cheng Wang, Lin-Sheng Lv, Ming Li, Xiao-Ming Wu and Tan-Qi Lou
    Citation: BMC Nephrology 2013 14:181
  37. This study describes chronic kidney disease of uncertain aetiology (CKDu), which cannot be attributed to diabetes, hypertension or other known aetiologies, that has emerged in the North Central region of Sri L...

    Authors: Nihal Jayatilake, Shanthi Mendis, Palitha Maheepala and Firdosi R Mehta
    Citation: BMC Nephrology 2013 14:180
  38. The quality of life (QOL) of patients with autosomal dominant polycystic kidney disease (ADPKD) has not been investigated well. This study was performed to clarify the QOL of patients with ADPKD and to identif...

    Authors: Tatsuya Suwabe, Yoshifumi Ubara, Koki Mise, Masahiro Kawada, Satoshi Hamanoue, Keiichi Sumida, Noriko Hayami, Junichi Hoshino, Rikako Hiramatsu, Masayuki Yamanouchi, Eiko Hasegawa, Naoki Sawa and Kenmei Takaichi
    Citation: BMC Nephrology 2013 14:179
  39. Hyperphosphatemia, serum phosphorus ≥ 4.4 mg/dL, is associated with increased risk for chronic kidney disease and cardiovascular disease. Previous studies have shown a weak association between dietary phosphor...

    Authors: Janet M Wojcicki
    Citation: BMC Nephrology 2013 14:178
  40. The number of individuals suffering from chronic kidney disease (CKD) is increasing. Therefore, early identification of modifiable predictors of CKD is highly desirable. Previous studies suggest an association...

    Authors: Gabriele Nagel, Emanuel Zitt, Raphael Peter, Alfonso Pompella, Hans Concin and Karl Lhotta
    Citation: BMC Nephrology 2013 14:177
  41. The number of elderly people over the age of 65 commencing dialysis in NZ has increased by almost 400% in the past decade. Few data are available about health related outcomes and survival on dialysis in the e...

    Authors: Robert Walker, Sarah Derrett, John Campbell, Mark R Marshall, Andrew Henderson, John Schollum, Sheila Williams and Bronwen McNoe
    Citation: BMC Nephrology 2013 14:175
  42. Warfarin prescribing patterns for hemodialysis patients with atrial fibrillation vary widely amongst nephrologists. This may be due to a paucity of guiding evidence, but also due to concerns of increased risks...

    Authors: Salina Juma, Benjamin KA Thomson, Charmaine E Lok, Catherine M Clase, Peter G Blake and Louise Moist
    Citation: BMC Nephrology 2013 14:174
  43. Chronic kidney disease (CKD) and coronary artery disease (CAD) are independently associated with increased vascular stiffness. We examined whether renal function contributes to vascular stiffness independently...

    Authors: Sabrina H Rossi, Emily P McQuarrie, William H Miller, Ruth M Mackenzie, Jane A Dymott, María U Moreno, Chiara Taurino, Ashley M Miller, Ulf Neisius, Geoffrey A Berg, Zivile Valuckiene, Jonathan A Hannay, Anna F Dominiczak and Christian Delles
    Citation: BMC Nephrology 2013 14:173
  44. In March, 2007, a black box warning was issued by the Food and Drug Administration (FDA) to use the lowest possible erythropoiesis-stimulating agents (ESA) doses for treatment of anemia associated with renal d...

    Authors: Mae Thamer, Yi Zhang, Dejian Lai, Onkar Kshirsagar and Dennis Cotter
    Citation: BMC Nephrology 2013 14:172
  45. Hyponatremia is often observed in patients with Legionella pneumonia. However, other electrolyte abnormalities are uncommon and the mechanism remains to be clarified.

    Authors: Naoko Kinoshita-Katahashi, Hirotaka Fukasawa, Sayaka Ishigaki, Shinsuke Isobe, Shiro Imokawa, Yoshihide Fujigaki and Ryuichi Furuya
    Citation: BMC Nephrology 2013 14:171
  46. Monitoring of the appearance of left ventricular hypertrophy (LVH) by echocardiography is currently recommended for in the management of children with End-stage renal disease (ESRD). In order to investigate th...

    Authors: Nikki J Schoenmaker, Johanna H van der Lee, Jaap W Groothoff, Gabrielle G van Iperen, Ingrid ME Frohn-Mulder, Ronald B Tanke, Jaap Ottenkamp and Irene M Kuipers
    Citation: BMC Nephrology 2013 14:170

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