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  1. Sphingosine-1-phosphate (S1P) is a bioactive metabolite of sphingolipids and produced by sphingosine kinases (SphK1 and SphK2). SphK1/S1P pathway is implicated in the progression of chronic kidney disease. How...

    Authors: Bingqing Lyu, Weili Wang, Xin-Ying Ji, Joseph K. Ritter and Ningjun Li
    Citation: BMC Nephrology 2020 21:173
    Content type: Research article Published on:

  2. Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim...

    Authors: Lei Yang, Xiaoxia Wu, Ying Wang, Chunfeng Wang, Rong Hu and Yong Wu
    Citation: BMC Nephrology 2020 21:172
    Content type: Research article Published on:

  3. Female Dent disease 1 patients with low-molecular-weight proteinuria (LMWP) due to CLCN5 gene mutation were rarely reported, and these cases that the people were also with Turner syndrome (TS) were even hardly do...

    Authors: Yuhong Ye, Jingjing Wang, Xiaofang Quan, Ke Xu, Haidong Fu, Weiyue Gu and Jianhua Mao
    Citation: BMC Nephrology 2020 21:171
    Content type: Case report Published on:

  4. Impaired kidney function is the hallmark of chronic kidney disease (CKD), and is associated with increased risk of all-cause mortality in the elderly. In the present cross-sectional population-based study, we ...

    Authors: Horng-Jinh Chang, Kuan-Reng Lin, Meng-Te Lin and Junn-Liang Chang
    Citation: BMC Nephrology 2020 21:169
    Content type: Research article Published on:

  5. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Daniela Gerges-Knafl, Peter Pichler, Alexander Zimprich, Christoph Hotzy, Wolfgang Barousch, Rita M. Lang, Elisabeth Lobmeyr, Sabina Baumgartner-Parzer, Ludwig Wagner and Wolfgang Winnicki
    Citation: BMC Nephrology 2020 21:168
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2020 21:117

  6. Studies of progression of kidney dysfunction typically focus on renal replacement therapy or percentage decline in estimated glomerular filtration rate (eGFR) as outcomes. Our aim was to compare real-world pat...

    Authors: Gregory A. Nichols, Anouk Déruaz-Luyet, Kimberly G. Brodovicz, Teresa M. Kimes, A. Gabriela Rosales and Sibylle J. Hauske
    Citation: BMC Nephrology 2020 21:167
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2020 21:200

  7. Low physical performance in patients undergoing maintenance hemodialysis is associated with a high mortality rate. We investigated the clinical relevance of gait speed and handgrip strength, the two most commo...

    Authors: Yu Ho Lee, Jin Sug Kim, Su-Woong Jung, Hyeon Seok Hwang, Ju-Young Moon, Kyung-Hwan Jeong, Sang-Ho Lee, So-Young Lee, Gang Jee Ko, Dong-Young Lee, Hong joo Lee and Yang Gyun Kim
    Citation: BMC Nephrology 2020 21:166
    Content type: Research article Published on:

  8. Limited data suggest serum chloride levels associate with mortality in heart failure, chronic kidney disease (CKD), and pulmonary arterial hypertension. Randomized trials have also shown that administration of...

    Authors: Minesh Khatri, Joshua Zitovsky, Dale Lee, Kamal Nayyar, Melissa Fazzari and Candace Grant
    Citation: BMC Nephrology 2020 21:165
    Content type: Research article Published on:

  10. Twice-weekly maintenance hemodialysis sessions in patients with end stage renal disease are commonly practiced due to economic constraints in developing countries including Eritrea. To ameliorate the paucity o...

    Authors: Saud Mohammed Raja and Yemane Seyoum
    Citation: BMC Nephrology 2020 21:163
    Content type: Research article Published on:

  11. Patients who were diagnosed with hematologic malignancies (HM) had a higher risk of acute kidney injury (AKI). This study applies the Bayesian networks (BNs) to investigate the interrelationships between AKI a...

    Authors: Yang Li, Xiaohong Chen, Yimei Wang, Jiachang Hu, Ziyan Shen and Xiaoqiang Ding
    Citation: BMC Nephrology 2020 21:162
    Content type: Research article Published on:

  12. Chronic kidney disease (CKD) is a common chronic condition and a rising public health issue with increased morbidity and mortality, even at an early stage. Primary care has a pivotal role in the early detectio...

    Authors: Steve A. Van den Bulck, Patrik Vankrunkelsven, Geert Goderis, Gijs Van Pottelbergh, Jonathan Swerts, Karolien Panis and Rosella Hermens
    Citation: BMC Nephrology 2020 21:161
    Content type: Research article Published on:

  13. To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and...

    Authors: Karan K. Shah, Fliss E. M. Murtagh, Kevin McGeechan, Susan M. Crail, Aine Burns and Rachael L. Morton
    Citation: BMC Nephrology 2020 21:160
    Content type: Research article Published on:

  15. The inflammatory mediator calprotectin (CPT, myeloid-related protein 8/14) is known as an endogenous ligand contributing to pathophysiology in inflammatory diseases. Serum CPT reportedly became a potential bio...

    Authors: Tomoko Kanki, Takashige Kuwabara, Jun Morinaga, Hirotaka Fukami, Shuro Umemoto, Daisuke Fujimoto, Teruhiko Mizumoto, Manabu Hayata, Yutaka Kakizoe, Yuichiro Izumi, Saeko Tajiri, Tetsuya Tajiri, Kenichiro Kitamura and Masashi Mukoyama
    Citation: BMC Nephrology 2020 21:158
    Content type: Research article Published on:

  16. Although urinary angiotensinogen (AGT) and renin reflect intrarenal renin-angiotensin system activity and are enhanced in proteinuric chronic kidney disease, the clinical value of urinary AGT and renin levels ...

    Authors: Junseok Jeon, Do Hee Kim, Hye Ryoun Jang, Jung Eun Lee, Wooseong Huh, Hye-Young Kim, Dae Joong Kim and Yoon-Goo Kim
    Citation: BMC Nephrology 2020 21:180
    Content type: Research article Published on:

  17. Xylitol is an approved food additive that is widely used as a sweetener in many manufactured products. It is also used in pharmaceuticals. Secondary oxalosis resulting from high dietary oxalate has been report...

    Authors: Shinobu Takayasu, Aya Kamba, Kazutaka Yoshida, Ken Terui, Yutaka Watanuki, Noriko Ishigame, Satoru Mizushiri, Tetsu Tomita, Kazuhiko Nakamura, Norio Yasui-Furukori and Makoto Daimon
    Citation: BMC Nephrology 2020 21:157
    Content type: Case report Published on:

  18. Regarding lupus disease activity, morbidity and survival, limited literature concluded conflicting results when comparing hemodialysis versus peritoneal dialysis as initial renal replacement therapies (RRT) pr...

    Authors: Joel Swai, Xiexiong Zhao, Julie-Raisa Noube and Gui Ming
    Citation: BMC Nephrology 2020 21:156
    Content type: Research article Published on:

  19. Abdominal aortic calcification assessed by X-ray is recommended to evaluate vascular calcification in dialysis patients. It has been shown that abdominal aortic calcification score (AACS) is a predictor of adv...

    Authors: Dahua Ma, Hao Yan, Xiaoxiao Yang, Zanzhe Yu, Zhaohui Ni and Wei Fang
    Citation: BMC Nephrology 2020 21:151
    Content type: Research article Published on:

  20. Whether ligation of the dorsal branch of the cephalic vein during the surgical establishment of the radiocephalic arteriovenous fistula (RCAVF) favorably or adversely affects the patency rate of the RCAVF rema...

    Authors: Hongtao Zhang, Guizhen Zhu, Lei Yan, Yang Lu and Fengmin Shao
    Citation: BMC Nephrology 2020 21:155
    Content type: Research article Published on:

  21. The oral health of patients undergoing renal replacement therapy (RRT) is insufficient. Poor oral health and its components can affect the oral health-related quality of life (OHRQoL) of these patients. The ai...

    Authors: Gerhard Schmalz, Susann Patschan, Daniel Patschan and Dirk Ziebolz
    Citation: BMC Nephrology 2020 21:154
    Content type: Research article Published on:

  22. Fluid overload (FO) assessed by bioimpedance spectroscopy (BIS) is associated with higher mortality risk in maintenance haemodialysis (HD). The aim was to assess if a better management of FO through short dail...

    Authors: Ana Beatriz Lesqueves Barra, Ana Paula Roque-da-Silva, Marcos S. Vasconcellos, Jocemir R. Lugon and Jorge Paulo Strogoff-de-Matos
    Citation: BMC Nephrology 2020 21:153
    Content type: Research article Published on:

  23. Dialysis patients are at high risk of developing glucose metabolism disturbances (GMDs), such as diabetes mellitus (DM), impaired fast glucose (IFG), and impaired glucose tolerance (IGT). However, it is unclea...

    Authors: Yanan Shi, Jiajie Cai, Chunxia Shi, Conghui Liu and Zhongxin Li
    Citation: BMC Nephrology 2020 21:152
    Content type: Research article Published on:

  24. Contrast-Associated Acute Kidney Injury (CA-AKI) is a serious complication associated with percutaneous coronary intervention (PCI). Patients with chronic kidney disease (CKD) have an elevated risk for develop...

    Authors: Joseph Walker Keach, Maggie A. Stanislawski, Anna E. Barón, Mary E. Plomondon, Paula Langner, Amit Amin, Heather M. Gilmartin, Stephen Waldo and Thomas M. Maddox
    Citation: BMC Nephrology 2020 21:150
    Content type: Research article Published on:

  26. There have been few systematic studies regarding clearance of uric acid (UA) in patients undergoing peritoneal dialysis (PD). This study investigated peritoneal UA removal and its influencing factors in patien...

    Authors: Xi Xiao, Hongjian Ye, Chunyan Yi, Jianxiong Lin, Yuan Peng, Xuan Huang, Meiju Wu, Haishan Wu, Haiping Mao, Xueqing Yu and Xiao Yang
    Citation: BMC Nephrology 2020 21:148
    Content type: Research article Published on:

  27. With the development and progression of genetic technology, preimplantation genetic testing (PGT) has made it possible to block the inheritance of autosomal dominant polycystic kidney disease (ADPKD) as early ...

    Authors: Mingji Sun, Cheng Xue, Yunhui Lu, Yiyi Ma, Ting Pan, Xiaoliu Wang, Li Fan, Jiandong Shen, Yan Hao, Danxia Zheng, Junhua Li, Mingxu Li, Yaping He and Changlin Mei
    Citation: BMC Nephrology 2020 21:147
    Content type: Research article Published on:

  28. Light chain proximal tubulopathy (LCPT) is a rare paraproteinemic renal disease that has been mostly reported in Western patients. LCPT is characterized by the accumulation of immunoglobulin (Ig)-light chain (...

    Authors: Minsun Jung, Youngeun Lee, Hajeong Lee and Kyung Chul Moon
    Citation: BMC Nephrology 2020 21:146
    Content type: Research article Published on:

  29. The relationship between kidney function and hearing loss has long been recognized, but evidence of this association mostly comes from small observational studies or other populations. The aim of this study is...

    Authors: Wenwen Liu, Qinqin Meng, Yafeng Wang, Chao Yang, Lili Liu, Huaiyu Wang, Zaiming Su, Guilan Kong, Yaohui Zhao and Luxia Zhang
    Citation: BMC Nephrology 2020 21:145
    Content type: Research article Published on:

  30. Aciduria caused by urinary excretion of acidic metabolic wastes produced in daily life is known to be augmented in patients with chronic kidney disease (CKD). To evaluate the reno-protective effect of oral alk...

    Authors: Michiaki Abe, Tetsuya Akaishi, Mutsumi Shoji, Takuhiro Yamaguchi, Takashi Miki, Fumitoshi Satoh, Shin Takayama, Satomi Yamasaki, Kazuhiko Kawaguchi, Hiroshi Sato, Tadashi Ishii and Sadayoshi Ito
    Citation: BMC Nephrology 2020 21:144
    Content type: Study protocol Published on:

  31. Contrast-induced nephropathy (CIN) following a percutaneous coronary intervention (PCI) is the third most common cause of acute kidney injury (AKI) worldwide. Patients who require hemodialysis secondary to CIN...

    Authors: Luis F. Reyes, Diego F. Severiche-Bueno, Carlos A. Bustamante, Sixta Murillo, Nilam J. Soni, Marcela Poveda, Efraín Gomez, Ricardo Buitrago and Alejandro Rodriguez
    Citation: BMC Nephrology 2020 21:143
    Content type: Research article Published on:

  32. Early detection of iron-deficiency anemia (IDA) can enhance the efficiency and effectiveness of clinical treatment and quality of life for end-stage renal disease (ESRD) patients. This study aimed to evaluate ...

    Authors: Nhan Hieu Dinh, Suzanne Monivong Cheanh Beaupha and Loan Thi Anh Tran
    Citation: BMC Nephrology 2020 21:142
    Content type: Research article Published on:

  33. The relationships between digestive bacterial translocation, uremic toxins, oxidative stress and microinflammation in a population of chronic kidney disease (CKD) patients without metabolic nor inflammatory di...

    Authors: Valerie Olivier, Catherine Dunyach-Remy, Pierre Corbeau, Jean-Paul Cristol, Thibault Sutra, Stephane Burtey, Jean-Philippe Lavigne and Olivier Moranne
    Citation: BMC Nephrology 2020 21:141
    Content type: Research article Published on:

  35. Following publication of the original article [1], we have been notified that the name of one author was spelled incorrectly as Georges N. Na khoul, when the correct spelling is Georges N. Nakhoul.

    Authors: Rami Azem, Remy Daou, Elias Bassil, Eva Maria Anvari, Jonathan J. Taliercio, Susana Arrigain, Jesse D. Schold, Tushar Vachharajani, Joseph Nally and Georges N. Nakhoul
    Citation: BMC Nephrology 2020 21:139
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2020 21:49

  36. Eosinophilic peritonitis is a relatively rare entity. Kimura’s disease is a rare chronic inflammatory disorder of unknown etiology, characterized by subcutaneous nodules mainly in the head and neck region, reg...

    Authors: Bingxin Yu, Zhikai Yang, Di Song, Zi Wang, Damin Xu, Suxia Wang, Lin Nong, Fude Zhou and Jie Dong
    Citation: BMC Nephrology 2020 21:138
    Content type: Case report Published on:

  37. Following publication of the original article [1]

    Authors: Osama Y. Safdar, Khalid A. Alhasan, Mohamed A. Shalaby, Norah Khathlan, Suleman A. Al Rezgan, Amr S. Albanna and Jameela A. Kari
    Citation: BMC Nephrology 2020 21:137
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2019 20:89

  38. Adults with end-stage renal disease (ESRD) requiring chronic dialysis continue to suffer from poor health outcomes and represent a population rightfully targeted for quality improvement. Electronic dashboards ...

    Authors: Michael J. Fischer, Wissam M. Kourany, Karen Sovern, Kurt Forrester, Cassandra Griffin, Nancy Lightner, Shawn Loftus, Katherine Murphy, Greg Roth, Paul M. Palevsky and Susan T. Crowley
    Citation: BMC Nephrology 2020 21:136
    Content type: Research article Published on:

  39. Lack of accurate and effective assessment tools of fluid status is one of the major challenges to reach proper dry weight (DW) in chronic hemodialysis (HD) population. The aim of this randomized study was to e...

    Authors: Li Liu, Yi Sun, Yuqing Chen, Jinsheng Xu, Ping Yuan, Yulan Shen, Shan Lin, Weiming Sun, Yingchun Ma, Jianwei Ren, Wenjun Liu, Jinghong Lei and Li Zuo
    Citation: BMC Nephrology 2020 21:135
    Content type: Research article Published on:

  40. Use of rituximab (RTX) for focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) is widely described in children. Clinical evidence in adults is limited. The objective of this study was to...

    Authors: Panupong Hansrivijit, Wisit Cheungpasitporn, Charat Thongprayoon and Nasrollah Ghahramani
    Citation: BMC Nephrology 2020 21:134
    Content type: Research article Published on:

  41. Patients with primary hyperoxaluria (PH) often develop kidney stones and chronic kidney disease. Noninvasive urine markers reflective of active kidney injury could be useful to gauge the effectiveness of ongoi...

    Authors: Xiangling Wang, Gauri Bhutani, Lisa E. Vaughan, Felicity T. Enders, Zejfa Haskic, Dawn Milliner and John C. Lieske
    Citation: BMC Nephrology 2020 21:133
    Content type: Research article Published on:

  43. Diabetic nephropathy (DN) is the most prevalent cause of renal disease in type 2 diabetic patients and is usually diagnosed clinically. A kidney biopsy is considered when non-diabetic renal disease (NDRD) is s...

    Authors: Jyh-Tong Hsieh, Fu-Pang Chang, An-Hang Yang, Der-Cherng Tarng and Chih-Yu Yang
    Citation: BMC Nephrology 2020 21:131
    Content type: Research article Published on:

  44. Chronic kidney disease is an increasingly common health problem for Aboriginal and Torres Strait Islander people. It is associated with multiple concurrent psychosocial stressors frequently resulting in negati...

    Authors: Tricia Nagel, Michelle Sweet, Kylie M. Dingwall, Stefanie Puszka, Jaquelyne T. Hughes, David J. Kavanagh, Alan Cass, Kirsten Howard and Sandawana W. Majoni
    Citation: BMC Nephrology 2020 21:130
    Content type: Research article Published on:

  46. Optimal clinical care of patients with chronic kidney disease (CKD) requires collaboration between primary care physicians (PCPs) and nephrologists. We undertook a randomised trial to determine the impact of s...

    Authors: Patrick Saudan, Belen Ponte, Nicola Marangon, Chantal Martinez, Lena Berchtold, David Jaques, Thomas Ernandez, Sophie de Seigneux, Sebastian Carballo, Thomas Perneger and Pierre-Yves Martin
    Citation: BMC Nephrology 2020 21:128
    Content type: Research article Published on:

  47. Vibrio vulnificus infection is a rare but fatal foodborne illness. Here, we report a case of Vibrio vulnificus peritonitis followed by severe septicemia in a patient undergoing continuous ambulatory peritoneal di...

    Authors: Jae Young Kim, Young Su Joo, Sangmi Lee, Ji Young Lee, Jung Tak Park, Seong Hyeok Han, Tae-Hyun Yoo and Shin-Wook Kang
    Citation: BMC Nephrology 2020 21:127
    Content type: Case report Published on:

  48. The prevalence of impaired cognitive functioning in older patients with end stage kidney disease (ESKD) is high. We aim to describe patterns of memory, executive function or psychomotor speed and to identify n...

    Authors: Floor J. van Deudekom, Marije H. Kallenberg, Noeleen C. Berkhout-Byrne, Gerard J. Blauw, Henk Boom, Jeroen de Bresser, Mark A. van Buchem, André Gaasbeek, Sebastiaan Hammer, Joep Lagro, Matthias J. P. van Osch, Marie-Noëlle Witjes-Ané, Ton J. Rabelink, Marjolijn van Buren and Simon P. Mooijaart
    Citation: BMC Nephrology 2020 21:126
    Content type: Research article Published on:

  49. Idiopathic nephrotic syndrome has a relapsing-remitting course in the majority of pediatric patients, demanding vigilant monitoring and self-management. A novel, expert-designed, user-informed mobile applicati...

    Authors: Chia-shi Wang, Cam Escoffery, Rachel E. Patzer, Courtney McCracken, Diana Ross, Michelle N. Rheault, Amira Al-Uzri and Larry A. Greenbaum
    Citation: BMC Nephrology 2020 21:125
    Content type: Study protocol Published on:

  50. Although the prevalence of kidney disease is higher in those with reduced lung function, the longitudinal relationship between low lung function and future risk of chronic kidney disease (CKD) has not been wid...

    Authors: Suneela Zaigham, Anders Christensson, Per Wollmer and Gunnar Engström
    Citation: BMC Nephrology 2020 21:124
    Content type: Research article Published on:
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BMC Nephrology

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