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  1. Research article

    Comparative differential proteomic analysis of minimal change disease and focal segmental glomerulosclerosis

    Minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS) are glomerular diseases characterized by nephrotic syndrome. Their diagnosis requires a renal biopsy, but it is an invasive pr...

    Vanessa Pérez, Dolores López, Ester Boixadera, Meritxell Ibernón, Anna Espinal, Josep Bonet and Ramón Romero

    BMC Nephrology 2017 18:49

    Published on: 3 February 2017

  2. Research article

    Association of estimated glomerular filtration rate and urine albumin-to-creatinine ratio with incidence of cardiovascular diseases and mortality in chinese patients with type 2 diabetes mellitus – a population-based retrospective cohort study

    Estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) are renal markers associated with risks of cardiovascular diseases (CVD) and all-cause mortality in diabetic patients. T...

    Colman Siu Cheung Fung, Eric Yuk Fai Wan, Anca Ka Chun Chan and Cindy Lo Kuen Lam

    BMC Nephrology 2017 18:47

    Published on: 2 February 2017

  3. Research article

    Fluid overload is an independent risk factor for acute kidney injury in critically Ill patients: results of a cohort study

    Acute Kidney injury (AKI) is common and increases mortality in the intensive care unit (ICU). We carried out this study to explore whether fluid overload is an independent risk factor for AKI.

    Nawal Salahuddin, Mustafa Sammani, Ammar Hamdan, Mini Joseph, Yasir Al-Nemary, Rawan Alquaiz, Ranim Dahli and Khalid Maghrabi

    BMC Nephrology 2017 18:45

    Published on: 1 February 2017

  4. Research article

    Combination therapy with rituximab, low-dose cyclophosphamide, and prednisone for idiopathic membranous nephropathy: a case series

    Membranous nephropathy is a common cause of the nephrotic syndrome. Treatment with standard regimens fails to induce complete remission in most patients. We evaluated the efficacy of combination therapy with r...

    Frank B. Cortazar, David E. Leaf, Charles T. Owens, Karen Laliberte, William F. Pendergraft and John L. Niles

    BMC Nephrology 2017 18:44

    Published on: 1 February 2017

  5. Research article

    Medication adherence in randomized controlled trials evaluating cardiovascular or mortality outcomes in dialysis patients: A systematic review

    Medication non-adherence is common among renal dialysis patients. High degrees of non-adherence in randomized controlled trials (RCTs) can lead to failure to detect a true treatment effect. Cardio-protective p...

    Karumathil M Murali, Judy Mullan, Jenny H. C. Chen, Steven Roodenrys and Maureen Lonergan

    BMC Nephrology 2017 18:42

    Published on: 31 January 2017

  6. Case report

    A novel case of renal pathergy reaction in a Behçet’s disease patient complicated by IgA vasculitis

    A pathergy reaction is defined as a hyperreactivity of the skin in response to minimal trauma, which is important in the diagnosis of Behçet’s disease (BD). However, a pathergy reaction may not be restricted t...

    Takaaki Higashihara, Akira Okada, Taiko Kusano, Kazuyoshi Ishigaki, Akira Shimizu and Hideki Takano

    BMC Nephrology 2017 18:40

    Published on: 28 January 2017

  7. Research article

    Protective effect of quinacrine against glycerol-induced acute kidney injury in rats

    Acute kidney injury (AKI) is a serious clinical problem with high rate of mortality and morbidity. Currently used prophylactic and therapeutic strategies to address AKI are limited and warrant further studies....

    Abdulrahman K. Al Asmari, Khalid Tariq Al Sadoon, Ali Ahmed Obaid, Deivakadatcham Yesunayagam and Mohammad Tariq

    BMC Nephrology 2017 18:41

    Published on: 28 January 2017

  8. Research article

    Prediction of clinical outcomes after kidney transplantation from deceased donors with acute kidney injury: a comparison of the KDIGO and AKIN criteria

    Acute kidney injury (AKI) is frequently detected in deceased donors (DDs), and it could be associated with adverse clinical outcomes in corresponding kidney transplant recipients (KTRs). In this regard, we sou...

    Jeong Ho Kim, Young Soo Kim, Min Seok Choi, Young Ok Kim, Sun Ae Yoon, Ji-Il Kim, In Sung Moon, Bum Soon Choi, Cheol Whee Park, Chul Woo Yang, Yong-Soo Kim and Byung Ha Chung

    BMC Nephrology 2017 18:39

    Published on: 27 January 2017

  9. Research article

    Gitelman syndrome in a South African family presenting with hypokalaemia and unusual food cravings

    Gitelman syndrome (GS) is an autosomal recessive renal tubular disorder characterised by renal salt wasting with hypokalaemia, metabolic alkalosis, hypomagnesaemia and hypocalciuria. It is caused by mutations in

    Pieter Du Toit van der Merwe, Megan A. Rensburg, William L. Haylett, Soraya Bardien and M. Razeen Davids

    BMC Nephrology 2017 18:38

    Published on: 26 January 2017

  10. Research article

    Costs of care at the end of life among elderly patients with chronic kidney disease: patterns and predictors in a nationwide cohort study

    Despite the urgent need for evidence to guide the end-of-life (EOL) care for patients with chronic kidney disease (CKD), we have limited knowledge of the costs and intensity of EOL care in this population. The...

    Bradley Chen, Victoria Y. Fan, Yiing-Jenq Chou and Chin-Chi Kuo

    BMC Nephrology 2017 18:36

    Published on: 26 January 2017

  11. Study protocol

    A prospective 2-site parallel intervention trial of a research-based film to increase exercise amongst older hemodialysis patients

    Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We ...

    Pia Kontos, Shabbir M.H. Alibhai, Karen-Lee Miller, Dina Brooks, Romeo Colobong, Trisha Parsons, Sarbjit Vanita Jassal, Alison Thomas, Malcolm Binns and Gary Naglie

    BMC Nephrology 2017 18:37

    Published on: 26 January 2017

  12. Research article

    Indoxyl sulfate – the uremic toxin linking hemostatic system disturbances with the prevalence of cardiovascular disease in patients with chronic kidney disease

    During chronic kidney disease progression, kidney-specific risk factors for cardiovascular disease come into play. The present study investigated the impact of indoxyl sulfate, dietary tryptophan-derived uremi...

    Tomasz W. Kamiński, Krystyna Pawlak, Małgorzata Karbowska, Michał Myśliwiec and Dariusz Pawlak

    BMC Nephrology 2017 18:35

    Published on: 25 January 2017

  13. Debate

    Diet in chronic kidney disease in a Mediterranean African country

    Mediterranean diet is characterized by low to moderate consumption of animal protein and high consumption of fruits, vegetables, bread, beans, nuts, seeds and other cereals. It has been associated with reduced...

    Khawla Kammoun, Hanen Chaker, Hichem Mahfoudh, Nouha Makhlouf, Faical Jarraya and Jamil Hachicha

    BMC Nephrology 2017 18:34

    Published on: 23 January 2017

  14. Research article

    The reverse remodeling of the aorta in patients after renal transplantation - the value of aortic stiffness index: prospective echocardiographic study

    Atherosclerosis is regarded as a combination of two major separate diseases: atherosis and sclerosis. Sclerotic component depends on deterioration of elastic properties of the aortic wall and is called aortic ...

    Tomasz Zapolski, Jacek Furmaga, Andrzej Jaroszyński, Anna Wysocka, Sławomir Rudzki and Andrzej P. Wysokiński

    BMC Nephrology 2017 18:33

    Published on: 23 January 2017

  15. Research article

    Genetic risk score and risk of stage 3 chronic kidney disease

    We developed a genetic risk score (GRS) and examined whether the GRS may predict incident stage 3 chronic kidney disease (CKD) independent of common clinical risk factors.

    Jiantao Ma, Qiong Yang, Shih-Jen Hwang, Caroline S. Fox and Audrey Y. Chu

    BMC Nephrology 2017 18:32

    Published on: 19 January 2017

  16. Study protocol

    A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury in living kidney donors: a protocol of a randomised controlled trial

    Optimal treatment for established renal failure is living donor kidney transplantation. However this pathway exposes healthy individuals to significant reduction in nephron mass via major surgical procedure. L...

    Shona Mackinnon, Emma Aitken, Ryan Ghita and Marc Clancy

    BMC Nephrology 2017 18:30

    Published on: 19 January 2017

  17. Research article

    Potential diagnostic biomarkers for chronic kidney disease of unknown etiology (CKDu) in Sri Lanka: a pilot study

    In Sri Lanka, there exists chronic kidney disease of both known (CKD) and unknown etiologies (CKDu). Identification of novel biomarkers that are customized to the specific causative factors would lead to early...

    Saravanabavan Sayanthooran, Dhammika N. Magana-Arachchi, Lishanthe Gunerathne and Tilak Abeysekera

    BMC Nephrology 2017 18:31

    Published on: 19 January 2017

  18. Research article

    Interaction between acyl-ghrelin and BMI predicts clinical outcomes in hemodialysis patients

    Ghrelin, a gastric orexigenic peptide, and body mass index (BMI) are known as inversely associated to each other and are both linked to cardiovascular (CV) risk and mortality in maintenance hemodialysis (MHD) ...

    Ilia Beberashvili, Inna Sinuani, Ada Azar, Gregory Shapiro, Leonid Feldman, Keren Doenyas-Barak, Kobi Stav and Shai Efrati

    BMC Nephrology 2017 18:29

    Published on: 18 January 2017

  19. Research article

    Increased glomerulonephritis recurrence after living related donation

    Kidney transplantation confers superior outcomes for patients with end stage kidney disease, and live donor kidneys associate with superior outcomes compared to deceased donor kidneys. Modern immunosuppression...

    A. L. Kennard, S. H. Jiang and G. D. Walters

    BMC Nephrology 2017 18:25

    Published on: 17 January 2017

  20. Research article

    Awareness and knowledge among internal medicine house-staff for dose adjustment of commonly used medications in patients with CKD

    Drug dosing errors result in adverse patient outcomes and are more common in patients with chronic kidney disease (CKD). As internists treat the majority of patients with CKD, we study if Internal Medicine hou...

    Sikander Surana, Neeru Kumar, Amita Vasudeva, Gulvahid Shaikh, Kenar D. Jhaveri, Hitesh Shah, Deepa Malieckal, Joshua Fogel, Gurwinder Sidhu and Sofia Rubinstein

    BMC Nephrology 2017 18:26

    Published on: 17 January 2017

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