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  1. Research article

    Accuracy of cystatin C in prediction of acute kidney injury in children; serum or urine levels: which one works better? A systematic review and meta-analysis

    There is still an ongoing discussion on the prognostic value of cystatin C in assessment of kidney function. Accordingly, the present study aimed to conduct a meta-analysis to provide evidence for the prognost...

    Babak Nakhjavan-Shahraki, Mahmoud Yousefifard, Neamatollah Ataei, Masoud Baikpour, Fatemeh Ataei, Behnaz Bazargani, Arash Abbasi, Parisa Ghelichkhani, Faezeh Javidilarijani and Mostafa Hosseini

    BMC Nephrology 2017 18:120

    Published on: 3 April 2017

  2. Research article

    Kidney disease in Uganda: a community based study

    Chronic kidney disease (CKD) is a major cause of morbidity and mortality in Sub-Saharan Africa (SSA). The majority of studies on CKD in SSA have been conducted among HIV-infected populations and mainly from la...

    Robert Kalyesubula, Joaniter I. Nankabirwa, Isaac Ssinabulya, Trishul Siddharthan, James Kayima, Jane Nakibuuka, Robert A. Salata, Charles Mondo, Moses R. Kamya and Donald Hricik

    BMC Nephrology 2017 18:116

    Published on: 3 April 2017

  3. Research article

    Relationship between serum bilirubin concentrations and diabetic nephropathy in Shanghai Han’s patients with type 1 diabetes mellitus

    Recent studies highlight a negative association between total bilirubin concentrations and albuminuria in patients with type 2 diabetes mellitus. Our study evaluated the relationship between bilirubin concentr...

    Xu Li, Lei Zhang, Haibing Chen, Kaifeng Guo, Haoyong Yu, Jian Zhou, Ming Li, Qing Li, Lianxi Li, Jun Yin, Fang Liu, Yuqian Bao, Junfeng Han and Weiping Jia

    BMC Nephrology 2017 18:114

    Published on: 31 March 2017

  4. Research article

    Plasma Urotensin II levels in children and adolescents with chronic kidney disease: a single-centre study

    Increased plasma Urotensin II (UII) levels have been found in adults with renal diseases. Studies in children are scarce. The objective of the study is to estimate plasma UII levels in subjects with chronic ki...

    Anastasia Garoufi, Styliani Drapanioti, Antonios Marmarinos, Varvara Askiti, Andromachi J. Mitsioni, Maria Mila, Georgia Grigoriadou, Dimitrios Georgakopoulos, Constantinos J. Stefanidis and Dimitrios Gourgiotis

    BMC Nephrology 2017 18:113

    Published on: 31 March 2017

  5. Case report

    Antenatal nephromegaly and propionic acidemia: a case report

    Propionic acidemia (PA) is a rare but severe recessive autosomal disease, presenting with non specific signs in the first years of life. Prenatal diagnosis is invasive (amniocentesis) and limited to suspect ca...

    Ségolène Bernheim, Georges Deschênes, Manuel Schiff, Isabelle Cussenot and Olivier Niel

    BMC Nephrology 2017 18:110

    Published on: 30 March 2017

  6. Research article

    Association of IL1 beta gene polymorphism and allograft functions in renal transplant recipients :a case control study from Kashmir Valley

    Cytokines have been found to be the important mediators during renal graft outcome. Therefore, we designed this study to investigate the role of recipients’ IL-1 β promoter (−511) and IL-1 β exon-5 (+3954) pol...

    Mohammad Ashraf Bhat, Manzoor Ahmad Parry, Saniya Nissar, Aga Syed Sameer, Imtiyaz A. Bhat, Zafar A. Shah and Roohi Rasool

    BMC Nephrology 2017 18:111

    Published on: 30 March 2017

  7. Research article

    Early urinary biomarkers of diabetic nephropathy in type 1 diabetes mellitus show involvement of kallikrein-kinin system

    Additional urinary biomarkers for diabetic nephropathy (DN) are needed, providing early and reliable diagnosis and new insights into its mechanisms. Rigorous selection criteria and homogeneous study population...

    Lenka Vitova, Zdenek Tuma, Jiri Moravec, Milan Kvapil, Martin Matejovic and Jan Mares

    BMC Nephrology 2017 18:112

    Published on: 30 March 2017

  8. Case report

    Successful multigravid pregnancy in a 42-year-old patient on continuous ambulatory peritoneal dialysis and a review of the literature

    For peritoneal dialysis patients, the likelihood of conception is low and the probability of getting through the pregnancy successfully is even lower. Almost 60 years after the first reported case of a success...

    Thiam Seong Christopher Lim, Malini Shanmuganathan, Irene Wong and Bak Leong Goh

    BMC Nephrology 2017 18:108

    Published on: 29 March 2017

  9. Research article

    Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation

    Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investiga...

    Jennifer Scheel, Sandra Reber, Lisa Stoessel, Elisabeth Waldmann, Sabine Jank, Kai-Uwe Eckardt, Franziska Grundmann, Frank Vitinius, Martina de Zwaan, Anna Bertram and Yesim Erim

    BMC Nephrology 2017 18:107

    Published on: 29 March 2017

  10. Case report

    Daclatasvir/asunaprevir based direct-acting antiviral therapy ameliorate hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis: a case report

    Direct-acting antivirals (DAAs) dramatically improve the treatment of hepatitis C virus (HCV) infections. However, the effects of DAAs on extra-hepatic manifestations such as HCV-associated glomerulonephritis,...

    Michiko Shimada, Norio Nakamura, Tetsu Endo, Hideaki Yamabe, Masayuki Nakamura, Reiichi Murakami, Ikuyo Narita and Hirofumi Tomita

    BMC Nephrology 2017 18:109

    Published on: 29 March 2017

  11. Research article

    Factors affecting the long-term outcomes of idiopathic membranous nephropathy

    We attempted to describe the clinical features and determine the factors associated with renal survival in idiopathic membranous nephropathy (iMN) patients with nephrotic syndrome (NS) and to determine the fac...

    Hyuk Huh, Hajeong Lee, Jung Pyo Lee, Dong Ki Kim, Sohee Oh, Yun Kyu Oh, Yon Su Kim and Chun Soo Lim

    BMC Nephrology 2017 18:104

    Published on: 27 March 2017

  12. Research article

    Hyperuricemia after orthotopic liver transplantation: divergent associations with progression of renal disease, incident end-stage renal disease, and mortality

    Although hyperuricemia is common after orthotopic liver transplantation (OLT), its relationship to mortality, progressive kidney disease, or the development of end stage renal disease (ESRD) is not well-descri...

    Joseph C. Longenecker, Sana Waheed, Ghassan Bandak, Christine A. Murakami, Blaithin A. McMahon, Allan C. Gelber and Mohamed G. Atta

    BMC Nephrology 2017 18:103

    Published on: 27 March 2017

  13. Case report

    Steroid-resistant nephrotic syndrome as the initial presentation of nail-patella syndrome: a case of a de novo LMX1B mutation

    Nail-patella syndrome (NPS) is an autosomal dominant disorder caused by mutations in the LMX1B gene and is characterized by nail dysplasia, skeletal abnormalities, and nephropathy. We herein report a case of s...

    Tomohiro Nakata, Ryo Ishida, Yuu Mihara, Atsuko Fujii, Yoshimoto Inoue, Tetsuro Kusaba, Tsuyoshi Isojima, Yutaka Harita, Chiaki Kanda, Sachiko Kitanaka and Keiichi Tamagaki

    BMC Nephrology 2017 18:100

    Published on: 23 March 2017

  14. Research article

    The risk of diabetic renal function impairment in the first decade after diagnosed of diabetes mellitus is correlated with high variability of visit-to-visit systolic and diastolic blood pressure: a case control study

    The variability of visit-to-visit (VVV) in systolic blood pressure (SBP) and diastolic blood pressure (DBP) is proved as a predictor of renal function deterioration in patients with non-diabetic chronic kidney...

    Chi-Hsiao Yeh, Hsiu-Chin Yu, Tzu-Yen Huang, Pin-Fu Huang, Yao-Chang Wang, Tzu-Ping Chen and Shun-Ying Yin

    BMC Nephrology 2017 18:99

    Published on: 22 March 2017

  15. Research article

    Higher plasma transforming growth factor (TGF)-β is associated with kidney disease in older community dwelling adults

    TGF-β is induced in the vasculature with aging suggesting that high plasma TGF-β levels may be a risk factor for chronic kidney disease (CKD) in older adults.

    Tapan Mehta, Petra Buzkova, Jorge R. Kizer, Luc Djousse, Michel Chonchol, Kenneth J. Mukamal, Michael Shlipak, Joachim H. Ix and Diana Jalal

    BMC Nephrology 2017 18:98

    Published on: 21 March 2017

  16. Case report

    Case report - atypical hemolytic uremic syndrome triggered by influenza B

    Influenza A infections have been described to cause secondary hemolytic uremic syndrome and to trigger atypical hemolytic uremic syndrome (aHUS) in individuals with an underlying genetic complement dysregulati...

    Robin Kobbe, Raphael Schild, Martin Christner, Jun Oh, Sebastian Loos and Markus J. Kemper

    BMC Nephrology 2017 18:96

    Published on: 20 March 2017

  17. Research article

    Delta neutrophil index is an independent predictor of mortality in septic acute kidney injury patients treated with continuous renal replacement therapy

    Delta neutrophil index (DNI), representing an elevated fraction of circulating immature granulocytes in acute infection, has been reported as a useful marker for predicting mortality in patients with sepsis. T...

    In Mi Han, Chang-Yun Yoon, Dong Ho Shin, Youn Kyung Kee, Seung Gyu Han, Young Eun Kwon, Kyoung Sook Park, Mi Jung Lee, Hyung Jung Oh, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang and Tae-Hyun Yoo

    BMC Nephrology 2017 18:94

    Published on: 20 March 2017

  18. Research article

    Cardiovascular risk is similar in patients with glomerulonephritis compared to other types of chronic kidney disease: a matched cohort study

    Patients with chronic kidney disease (CKD) due to glomerulonephritis (GN) are thought to be at high risk for cardiovascular disease (CVD). However, no study has examined whether GN directly contributes to CV r...

    Holly L. Hutton, Adeera Levin, Jagbir Gill, Ognjenka Djurdjev, Mila Tang and Sean J. Barbour

    BMC Nephrology 2017 18:95

    Published on: 20 March 2017

  19. Research article

    Renal effects of metallothionein induction by zinc in vitro and in vivo

    Metallothionein (MTT) is an endogenous antioxidant that can be induced by both zinc (Zn) and ischemia. In kidneys, increased MTT expression exerts a putative protective role in diabetes and hypoxia. Our goal w...

    Moritz Schanz, Lea Schaaf, Juergen Dippon, Dagmar Biegger, Peter Fritz, Mark Dominik Alscher and Martin Kimmel

    BMC Nephrology 2017 18:91

    Published on: 16 March 2017

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