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  1. Research article

    Simple, readily available clinical indices predict early and late mortality among patients with ANCA-associated vasculitis

    The early identification of patients with ANCA-associated vasculitis (AAV) who are at increased risk for inferior clinical outcome at the time of diagnosis might help to optimize the immunosuppressive therapy....

    Ágnes Haris, Kálmán Polner, József Arányi, Henrik Braunitzer, Ilona Kaszás, László Rosivall, Gábor Kökény and István Mucsi

    BMC Nephrology 2017 18:76

    Published on: 23 February 2017

  2. Research article

    The association of kidney function with repetitive breath-hold diving activities of female divers from Korea, Haenyeo

    Voluntary apnea during breath-hold diving (BHD) induces cardiovascular changes including bradycardia, reduced cardiac output, and arterial hypertension. Although the impacts of repetitive BHD on cardiovascular...

    Yun Jung Oh, Ji Yong Jung, Sung Soo Kim, Kyong-Suk Chae, Jiwon Rhu and Chungsik Lee

    BMC Nephrology 2017 18:75

    Published on: 23 February 2017

  3. Research article

    Vascular access conversion and patient outcome after hemodialysis initiation with a nonfunctional arteriovenous access: a prospective registry-based study

    Little is known about vascular access conversion and outcomes for patients starting hemodialysis with nonfunctional arteriovenous (AV) access. We assessed mortality risk associated with nonfunctional AV access...

    Natalia Alencar de Pinho, Raphael Coscas, Marie Metzger, Michel Labeeuw, Carole Ayav, Christian Jacquelinet, Ziad A Massy and Bénédicte Stengel

    BMC Nephrology 2017 18:74

    Published on: 22 February 2017

  4. Research article

    NGAL expression during cardiopulmonary bypass does not predict severity of postoperative acute kidney injury

    Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGA...

    Martin G. Friedrich, Ioannis Bougioukas, Johanna Kolle, Christian Bireta, Fawad A. Jebran, Marius Placzek and Theodor Tirilomis

    BMC Nephrology 2017 18:73

    Published on: 21 February 2017

  5. Research article

    Ultrafiltration rate is an important determinant of microcirculatory alterations during chronic renal replacement therapy

    Hemodialysis (HD) with ultrafiltration (UF) in chronic renal replacement therapy is associated with hemodynamic instability, morbidity and mortality. Sublingual Sidestream Dark Field (SDF) imaging during HD re...

    Gerke Veenstra, Andrius Pranskunas, Inga Skarupskiene, Vidas Pilvinis, Marc H. Hemmelder, Can Ince and E. Christiaan Boerma

    BMC Nephrology 2017 18:71

    Published on: 20 February 2017

  6. Research article

    Non anti-coagulant factors associated with filter life in continuous renal replacement therapy (CRRT): a systematic review and meta-analysis

    Optimising filter life and performance efficiency in continuous renal replacement therapy has been a focus of considerable recent research. Larger high quality studies have predominantly focussed on optimal an...

    Matthew Brain, Elizabeth Winson, Owen Roodenburg and John McNeil

    BMC Nephrology 2017 18:69

    Published on: 20 February 2017

  7. Research article

    Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria

    Acute kidney injury (AKI) is a serious complication of critical illness with both attributed morbidity and mortality at short-term and long-term. The incidence of AKI reported in critically ill patients varies...

    J. Koeze, F. Keus, W. Dieperink, I. C. C. van der Horst, J. G. Zijlstra and M. van Meurs

    BMC Nephrology 2017 18:70

    Published on: 20 February 2017

  8. Research article

    Surfactant protein-D (SP-D) gene polymorphisms and serum level as predictors of susceptibility and prognosis of acute kidney injury in the Chinese population

    Injury to the kidney epithelial barrier is a characteristic feature of acute kidney injury (AKI). Serum surfactant protein-D (SP-D), a known biomarker of damaged alveolar epithelium, is also secreted by renal ...

    Jiao Liu, Guang Li, Lianghai Li, Zhiyong Liu, Qingshan Zhou, Guirong Wang and Dechang Chen

    BMC Nephrology 2017 18:67

    Published on: 17 February 2017

  9. Research article

    Risedronate therapy in patients with mild-to-moderate chronic kidney disease with osteoporosis: post-hoc analysis of data from the risedronate phase III clinical trials

    The clinical effect of bisphosphonate treatment has not been clearly evaluated by kidney function in Japanese Chronic Kidney Disease (CKD) patients with osteoporosis. This study analyzed the data from three ri...

    Takashi Shigematsu, Ryoichi Muraoka, Toshitsugu Sugimoto and Yoshiki Nishizawa

    BMC Nephrology 2017 18:66

    Published on: 15 February 2017

  10. Research article

    Prevalence and risk factors for Human T-Lymphotropic Virus Type 1 (HTLV-1) among maintenance hemodialysis patients

    Infection with the human T-cell lymphotropic virus type 1 (HTLV-1), although asymptomatic in most cases, can lead to potentially grave consequences, such as adult T-cell leukemia-lymphoma and HTLV-1-associated...

    Rilma F. S. Santos, Gildásio C. Conceição, Márcia S. Martins, Angiolina Kraychete, Maria A. C. Penalva, Edgar M. Carvalho, Antonio Alberto Lopes and Paulo Novis Rocha

    BMC Nephrology 2017 18:64

    Published on: 15 February 2017

  11. Research article

    The association between interleukin-19 concentration and diabetic nephropathy

    Interleukin-19 (IL-19) is a newly discovered cytokine belonging to the Interleukin-10(IL-10) family. IL-19 have indispensable functions in many inflammatory processes and also can induce the angiogenic potenti...

    Li Li, Xu-gan Jiang, Juan-Yu Hu, ZHeng-Qing Yu, Jian-Yong Xu, Fan Liu, Guang-Chun Zhao, Lei Zhang, Hui-Ming Gu, Si-Jing Zhang and Jin Meng

    BMC Nephrology 2017 18:65

    Published on: 15 February 2017

  12. Research article

    Urinary sediment miRNAs reflect tubulointerstitial damage and therapeutic response in IgA nephropathy

    Immunoglobulin A nephropathy (IgAN) is the most common glomerulonephritis worldwide. The clinical spectrum of IgAN varies from minor urinary abnormalities to rapidly progressive renal failure. Evaluation of th...

    Shuang Liang, Guang-Yan Cai, Zhi-Yu Duan, Shu-wen Liu, Jie Wu, Yang Lv, Kai Hou, Zuo-xiang Li, Xue-Guang Zhang and Xiang-Mei Chen

    BMC Nephrology 2017 18:63

    Published on: 15 February 2017

  13. Research article

    Acute kidney injury increases the risk of end-stage renal disease after cardiac surgery in an Asian population: a prospective cohort study

    Acute kidney injury (AKI) after cardiac surgery is associated with increased morbidity and mortality. The long-term association between AKI and end-stage renal disease (ESRD) in an Asian population is unknown....

    Sophia Tsong Huey Chew, Roderica Rui Ge Ng, Weiling Liu, Khuan Yew Chow and Lian Kah Ti

    BMC Nephrology 2017 18:60

    Published on: 13 February 2017

  14. Research article

    Efficacy and safety of calcineurin inhibitor treatment for IgA nephropathy: a meta-analysis

    IgA nephropathy is the most common progressive glomerular disease to end stage renal failure worldwide. Calcineurin inhibitors (CNIs) is a selective immunosuppressant widely used in organ transplantation. The ...

    Yu-Huan Song, Guang-Yan Cai, Yue-Fei Xiao, Yi-Ping Wang, Bao-Shi Yuan, Yuan-Yuan Xia, Si-Yang Wang, Pu Chen, Shu-Wen Liu and Xiang-Mei Chen

    BMC Nephrology 2017 18:61

    Published on: 13 February 2017

  15. Case report

    Intestinal goblet cell carcinoid presenting with recurrent sterile peritonitis in a patient on peritoneal dialysis: a case report

    Goblet cell carcinoid is a rare variant of appendiceal carcinoid with mixed endocrine and exocrine features. The most common symptom and signs are abdominal pain, acute appendicitis and palpable mass. Addition...

    Chih-Wei Chen, Jan-Show Chu, Li-Chun Hsieh, Chih-Chin Kao, Yen-Chung Lin and Hsi-Hsien Chen

    BMC Nephrology 2017 18:62

    Published on: 13 February 2017

  16. Research article

    Estimation of renal function by CKD-EPI versus MDRD in a cohort of HIV-infected patients: a cross-sectional analysis

    Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today ...

    M. P. Cristelli, F. Cofán, N. Rico, J. C. Trullàs, C. Manzardo, F. Agüero, J. L. Bedini, A. Moreno, F. Oppenheimer and J. M. Miro

    BMC Nephrology 2017 18:58

    Published on: 10 February 2017

  17. Research article

    Low renal replacement therapy incidence among slowly progressing elderly chronic kidney disease patients referred to nephrology care: an observational study

    Elderly patients with advanced chronic kidney disease (CKD) have a high risk of death before reaching end-stage kidney disease. In order to allocate resources, such as advanced care nephrology where it is most...

    Ulrika Hahn Lundström, Alessandro Gasparini, Rino Bellocco, Abdul Rashid Qureshi, Juan-Jesus Carrero and Marie Evans

    BMC Nephrology 2017 18:59

    Published on: 10 February 2017

  18. Research article

    Transformation of 5-D itch scale and numerical rating scale in chronic hemodialysis patients

    Pruritus is a common and frustrating symptom in hemodialysis (HD) patients and 5-D itch scale is proposed as a reliable measurement of pruritus. However, information regarding 5-D itch scale categories is curr...

    Jia-Wen Lai, Hung-Chih Chen, Che-Yi Chou, Hung-Rong Yen, Tsai-Chung Li, Mao-Feng Sun, Hen-Hong Chang, Chiu-Ching Huang, Fuu-Jen Tsai, Johannes Tschen and Chiz-Tzung Chang

    BMC Nephrology 2017 18:56

    Published on: 8 February 2017

  19. Research article

    Latent variable modeling improves AKI risk factor identification and AKI prediction compared to traditional methods

    Acute kidney injury (AKI) is diagnosed based on postoperative serum creatinine change, but AKI models have not consistently performed well, in part due to the omission of clinically important but practically u...

    Loren E. Smith, Derek K. Smith, Jeffrey D. Blume, Edward D. Siew and Frederic T. Billings

    BMC Nephrology 2017 18:55

    Published on: 8 February 2017

  20. Research article

    Delineation of cystinuria in Saudi Arabia: A case series

    Cystinuria is an inherited metabolic disease that is caused by defects in two genes, SLC3A1 and SLC7A9, which result in a renal reabsorptive defect of cystine and other dibasic amino acids, including ornithine, a...

    Abdulrahman Obaid, Marwan Nashabat, Khalid Al Fakeeh, Abdullah T. Al Qahtani and Majid Alfadhel

    BMC Nephrology 2017 18:50

    Published on: 6 February 2017

  21. Research article

    Effect of large weight reductions on measured and estimated kidney function

    When patients experience large weight loss, muscle mass may be affected followed by changes in plasma creatinine (pCr). The MDRD and CKD-EPI equations for estimated GFR (eGFR) include pCr. We hypothesised that...

    Bernt Johan von Scholten, Frederik Persson, Maria S. Svane, Tine W. Hansen, Sten Madsbad and Peter Rossing

    BMC Nephrology 2017 18:52

    Published on: 6 February 2017

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