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  1. Optimal management of anemia of chronic kidney disease (CKD) remains controversial. This retrospective study aimed to describe the epidemiology and selected clinical outcomes of anemia in patients with CKD in ...

    Authors: Lois Lamerato, Glen James, Heleen van Haalen, Katarina Hedman, James A. Sloand, Amy Tang, Eric T. Wittbrodt and Jerry Yee
    Citation: BMC Nephrology 2022 23:166
    Content type: Research Published on:

  2. The prevalence of idiopathic membranous nephropathy (IMN) is increasing worldwide and the gut microbiota is recognized to play a role in its pathology. The aim of this study was to understand the involvement o...

    Authors: Mengfei Li, Lixue Wei, Jing Sun, Qianshen Zhu, He Yang, Yu Zhang, Chao Zhang, Lin Xi, Rong Zhao and Xuanyi Du
    Citation: BMC Nephrology 2022 23:164
    Content type: Research Published on:

  3. To date, nephrotic syndrome (NS) has not been well characterized in patients with IgA nephropathy (IgAN). Whether decline in serum albumin is an ominous sign in IgAN patients with massive proteinuria remains u...

    Authors: Hongfen Li, Fanghao Wang, Junya Jia, Tiekun Yan, Youxia Liu and Shan Lin
    Citation: BMC Nephrology 2022 23:163
    Content type: Research Published on:

  4. The progression of chronic kidney disease (CKD) is associated with an increasing risk of cardiovascular morbidity and mortality due to elevated serum phosphate levels. Besides low phosphate diets and hemodialy...

    Authors: Jacqueline Hofrichter, Kai Sempert, Claus Kerkhoff, Anne Breitrück, Reinhold Wasserkort and Steffen Mitzner
    Citation: BMC Nephrology 2022 23:162
    Content type: Research Published on:

  5. Diabetic nephropathy is the leading cause of kidney failure. Clinical practice guidelines recommend prescribing renin–angiotensin aldosterone system inhibitors (RAASi) to prevent diabetic nephropathy at any st...

    Authors: Noor Alsalemi, Cheryl A. Sadowski, Naoual Elftouh, Maudeline Louis, Kelley Kilpatrick, Sherilyn K. D. Houle and Jean-Philippe Lafrance
    Citation: BMC Nephrology 2022 23:161
    Content type: Research Published on:

  7. Chronic kidney disease has been linked to worse cognition. However, this association may be dependent on the marker of kidney function used, and studies assessing modification by genetics are lacking. This stu...

    Authors: Erin L. Richard, Linda K. McEvoy, Ian J. Deary, Gail Davies, Steven Y. Cao, Eyal Oren, John E. Alcaraz, Andrea Z. LaCroix, Jan Bressler and Rany M. Salem
    Citation: BMC Nephrology 2022 23:159
    Content type: Research Published on:

  8. Therapeutic strategies, including dietary intervention, to target non-dialysis dependent Chronic Kidney Disease (CKD) progression have been at the forefront of recent renal research. Nephrologists and other re...

    Authors: Stephanie Notaras, Kelly Lambert, Janette Perz and Angela Makris
    Citation: BMC Nephrology 2022 23:158
    Content type: Research Published on:

  9. Hyperuricemia and diabetes mellitus (DM) are associated with increased mortality risk in patients with chronic kidney disease (CKD). Here we aimed to evaluate the independent and joint risks of these two condi...

    Authors: Cheng-Hung Li, Chia-Lin Lee, Yu-Cheng Hsieh, Cheng-Hsu Chen, Ming-Ju Wu and Shang-Feng Tsai
    Citation: BMC Nephrology 2022 23:157
    Content type: Research Published on:

  10. Neutrophil gelatinase-associated lipocalin (NGAL) is not only a bone-derived factor involved in metabolism, but also a biomarker of kidney disease and cardiovascular pathophysiology. We conducted this cross-se...

    Authors: Kai Wei, Gesheng Song, Linhe Xi, Juan Chen, Chuancai Sun, Ping Chen, Yong Wei, Li Wang, Xianglei Kong, Yang Li, Dongmei Xu and Xiaoyan Jia
    Citation: BMC Nephrology 2022 23:156
    Content type: Research article Published on:

  11. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) may coexist with rheumatoid arthritis (RA). However, it is unclear whether the manifestations of AAV with and without coexisting RA are s...

    Authors: Haiting Wu, Yiyun Lu, Rongrong Hu, Wei Ye, Yubing Wen, Jianfang Cai, Hang Li and Xuemei Li
    Citation: BMC Nephrology 2022 23:155
    Content type: Research article Published on:

  12. There is controversy regarding the impact of delayed graft function (DGF) on kidney transplant outcomes. We hypothesize that the duration of DGF, rather than DGF itself, is associated with long-term kidney gra...

    Authors: Pooja Budhiraja, Kunam S Reddy, Richard J Butterfield, Caroline C Jadlowiec, Adyr A. Moss, Hassan A Khamash, Lavanya Kodali, Suman S Misra and Raymond L Heilman
    Citation: BMC Nephrology 2022 23:154
    Content type: Research Published on:

  13. Steroid pulse (SP) therapy is one of the immunosuppressive therapies for immunoglobulin A nephropathy (IgAN). Although there are various protocols of SP therapy in IgAN, the intermittent SP (ISP) and consecuti...

    Authors: Satoshi Yamatani, Keiji Kono, Hideki Fujii, Ken Hirabayashi, Mao Shimizu, Kentaro Watanabe, Shunsuke Goto and Shinichi Nishi
    Citation: BMC Nephrology 2022 23:153
    Content type: Research Published on:

  14. Peer support complements traditional models of chronic kidney disease (CKD) care through sharing of peer experiences, pragmatic advice, and resources to enhance chronic kidney disease self-management and decis...

    Authors: Shannan Love, Tyrone G. Harrison, Danielle E. Fox, Maoliosa Donald, Nancy Verdin, Brenda R. Hemmelgarn and Meghan J. Elliott
    Citation: BMC Nephrology 2022 23:152
    Content type: Research Published on:

  16. Sunitinib-induced high-grade proteinuria and irreversible renal allograft dysfunction are rare conditions. Here, we present a patient who had received renal allograft and later developed metastatic clear cell ...

    Authors: Hsu-Cheng Ko, Huai-Pao Lee, Jiann-Der Wu, Tsung-Liang Ma, Cheng-Huang Shen, Chang-Te Lin, Ming-Chin Cheng and Yeong-Chin Jou
    Citation: BMC Nephrology 2022 23:150
    Content type: Case report Published on:

  17. Eosinophilic peritonitis is a well-known complication at the initiation of peritoneal dialysis. It is often due to an allergic reaction to peritoneal dialysis solution or sometimes to the peritoneal dialysis c...

    Authors: Zi Chan, Yun Ho Hui and Sunny Sze Ho Wong
    Citation: BMC Nephrology 2022 23:149
    Content type: Case report Published on:

  18. Acute and chronic kidney diseases are important comorbidities in People Living With HIV (PLWH). Biopsy is often pursued in this cohort with ongoing renal impairment without a clear aetiology, in order to estab...

    Authors: Dane Turner, Doug Drak, David Gracey and Lyndal Anderson
    Citation: BMC Nephrology 2022 23:148
    Content type: Research Published on:

  20. Renal perfusion may redistribute from cortex to medulla during systemic hypovolaemia and after renal ischaemia for other reasons, but there is no consensus on this matter. We studied renal perfusion after rena...

    Authors: Michael Rehling, Stine Gram Skjøth, Jørgen Frøkiær, Lene Elsebeth Nielsen, Christian Flø, Bente Jespersen and Anna Krarup Keller
    Citation: BMC Nephrology 2022 23:146
    Content type: Research article Published on:

  21. Little data exists on the prevalence of chronic kidney disease (CKD) in the Russian population. We aimed to estimate the prevalence of CKD in a population-based study in Russia, compare with a similar study in...

    Authors: Sarah Cook, Marit D. Solbu, Anne Elise Eggen, Olena Iakunchykova, Maria Averina, Laila A. Hopstock, Kamila Kholmatova, Alexander V. Kudryavtsev, David A. Leon, Sofia Malyutina, Andrew Ryabikov, Elizabeth Williamson and Dorothea Nitsch
    Citation: BMC Nephrology 2022 23:145
    Content type: Research Published on:

  23. IgA nephropathy (IgAN), which has been reported as the most prevalent glomerulonephritis globally, is the major contributor to end-stage renal diseases. This bioinformatics study aimed to explore glomerulotubu...

    Authors: Yawen Bai, Yajing Li, Yali Xi and Chunjie Ma
    Citation: BMC Nephrology 2022 23:143
    Content type: Research Published on:

  25. Among the possible causes of hypertension in adolescence, electrolyte imbalances and environmental pollutants are drawing increasing attention. We aimed to examine the relationship between bisphenol A (BPA), p...

    Authors: Siddika Songül Yalçin, İzzet Erdal, Berna Oğuz and Ali Duzova
    Citation: BMC Nephrology 2022 23:141
    Content type: Research Published on:

  26. Acute kidney injury (AKI) can lead to chronic kidney disease, which results in poor long-term outcomes. There is plausibility that increased levels of physical activity may promote renal recovery post-AKI. Thi...

    Authors: Anam Asad, Amal Thomas, Maurice Dungey, Katherine L. Hull, Daniel S. March and James O. Burton
    Citation: BMC Nephrology 2022 23:140
    Content type: Research Published on:

  27. Minimal change disease (MCD) is a common cause of the nephrotic syndrome. Several studies have shown an increased incidence of cancer in patients with MCD. However, there are no reports on the association betw...

    Authors: Chun-Yang Yu, Jie Liu, Chang-Hai Qi, Zhen-Yu Wu, Yue-Fei Xiao and Xue-Guang Zhang
    Citation: BMC Nephrology 2022 23:139
    Content type: Case report Published on:

  28. Adherence of patients with End-Stage Renal Disease (ESRD) to Hemodialysis (HD), prescribed medications, diet and fluid restrictions is essential to get the desirable outcome and prevent complications. During C...

    Authors: Basma Osman Sultan, Ahmed Mahmoud Fouad and Heba M. Zaki
    Citation: BMC Nephrology 2022 23:138
    Content type: Research Published on:

  29. Survivors of critical illness and acute kidney injury (AKI) are at risk of increased morbidity. The purpose of this study was to compare physical, emotional, and cognitive health in survivors of critical illne...

    Authors: Kirby P. Mayer, Victor M. Ortiz-Soriano, Alborz Kalantar, Joshua Lambert, Peter E. Morris and Javier A. Neyra
    Citation: BMC Nephrology 2022 23:137
    Content type: Research Published on:

  30. Aplastic anemia (AA) is a rare but fatal disorder characterized by pancytopenia due to bone marrow hypoplasia. Anti-glomerular basement membrane disease (anti-GBM disease) is an immune complex small-vessel vas...

    Authors: Kenji Matsui, Wataru Kamata, Yasuhiro Mochida, Kunihiro Ishioka, Hidekazu Moriya, Sumi Hidaka, Takayasu Ohtake, Yotaro Tamai and Shuzo Kobayashi
    Citation: BMC Nephrology 2022 23:136
    Content type: Case report Published on:

  32. Membranous Nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Recognition of MN as an antibody mediated autoimmune disease has enabled the introduction of anti-B-cell therapy. Rituximab, ...

    Authors: Rebecca Hudson, Cassandra Rawlings, Saw Yu Mon, Julia Jefferis and George T. John
    Citation: BMC Nephrology 2022 23:134
    Content type: Case report Published on:

  33. According to dietary recommendations, reduction of sodium intake has potential to reduce Chronic Kidney Disease (CKD) risk; however the role of dietary potassium and the sodium -to- potassium ratio in the deve...

    Authors: Samuel L. Swift, Yelena Drexler, Daniela Sotres-Alvarez, Leopoldo Raij, Maria M. Llabre, Neil Schneiderman, Linda Van Horn, James P. Lash, Yasmin Mossavar-Rahmani and Tali Elfassy
    Citation: BMC Nephrology 2022 23:133
    Content type: Research Published on:

  34. In the light of recent years, an increase in the number of life-threatening infections due to various fungi has been observed, especially in tertiary care centres. With Amphotericin B labelled as the first cho...

    Authors: Yusri Abdel-Hafez, Hani Siaj, Mohammad Janajri, Yazan Abu-Baker, Zaher Nazzal, Zakaria Hamdan, Rabee Adwan, Banan M. Aiesh and Ahmad I. Anaya
    Citation: BMC Nephrology 2022 23:132
    Content type: Research Published on:

  35. Up to 60% of pediatric renal transplant recipients with end-stage renal disease due to primary focal and segmental glomerulosclerosis (FSGS) may develop recurrent disease. Such recurrence is associated with po...

    Authors: Jaime M. Restrepo, Laura Torres-Canchala, Hernando Londoño, Eliana Manzi and Michael J. G. Somers
    Citation: BMC Nephrology 2022 23:131
    Content type: Research Published on:

  36. Different dialysis treatments may affect the composition and structure of the intestinal flora of dialysis-treated chronic kidney disease (CKD) patients. This study aimed to analyze the correlations between th...

    Authors: Jianguang Hu, Xiaoshi Zhong, Yan Liu, Jing Yan, Daoyuan Zhou, Danping Qin, Xiao Xiao, Yuanyuan Zheng, Luona Wen, Rongshao Tan, Pan Liang and Yun Liu
    Citation: BMC Nephrology 2022 23:130
    Content type: Research Published on:

  37. Aortic valve stenosis (AS) has a high prevalence and poor prognosis in patients who receive maintenance dialysis. However, few large-scale observational studies in Japan have investigated patients with AS who ...

    Authors: Yuji Sasakawa, Naoki Okamoto, Maya Fujii, Jyoichiro Kato, Yukio Yuzawa and Daijo Inaguma
    Citation: BMC Nephrology 2022 23:129
    Content type: Research Published on:

  39. Published literatures on repeat renal biopsy of AL amyloidosis have basically reached a consensus that amyloid material deposit does not disappear or diminish after satisfactory hematologic response, regardles...

    Authors: Ping Zhang, Xiuling Chen, Yurong Zou, Wei Wang and Yunlin Feng
    Citation: BMC Nephrology 2022 23:127
    Content type: Case report Published on:

  40. Depressive symptoms, fatigue, and poor sleep quality are associated with renal function deterioration in patients with nondialysis chronic kidney disease (CKD-ND). This study was designed to examine whether fa...

    Authors: Ya-Fang Ho, Pei-Ti Hsu and Kai-Ling Yang
    Citation: BMC Nephrology 2022 23:126
    Content type: Research Published on:

  42. Nuclear receptor-binding SET domain protein 2 (NSD2) is a histone methyltransferase that has been demonstrated to regulate insulin secretion and glucose concentration. This study focused on the role of NSD2 in...

    Authors: Weiming Tang, Yilin Zhao, Hui Zhang, Ying Peng and Zhilian Rui
    Citation: BMC Nephrology 2022 23:124
    Content type: Research Published on:

  43. Cardiovascular (CV) disease is the leading cause of mortality in patients with end-stage kidney disease (ESKD). The aim of the present study was to determine whether Proprotein Convertase Subtilisin/Kexin type...

    Authors: François-Pantaléon Musungayi Kajingulu, François Bompeka Lepira, Aliocha Natuhoyila Nkodila, Jean-Robert Rissassy Makulo, Vieux Momeme Mokoli, Pepe Mfutu Ekulu, Justine Busanga Bukabau, Yannick Mayamba Nlandu, Augustin Luzayadio Longo, Nazaire Mangani Nseka, Laura Labriola and Ernest Kiswaya Sumaili
    Citation: BMC Nephrology 2022 23:123
    Content type: Research Published on:

  44. Haemolytic uraemic syndrome (HUS) is a severe syndrome that causes a substantial burden for patients and their families and is the leading cause of acute kidney injury in children. However, data on the epidemi...

    Authors: Jingnan Feng, Ke Xu, Xinmiao Shi, Lu Xu, Lili Liu, Fang Wang, Xuhui Zhong, Guozhen Liu, Jinxi Wang, Pei Gao, Jie Ding, Shengfeng Wang and Siyan Zhan
    Citation: BMC Nephrology 2022 23:122
    Content type: Research Published on:

  45. Informed dialysis selection and greater home dialysis use are the two long-desired, underachieved targets of advanced chronic kidney disease (CKD) care in the US healthcare system. Observational institutional ...

    Authors: Ashutosh M. Shukla, Jennifer Hale-Gallardo, Tatiana Orozco, Ivette Freytes, Zachary Purvis, Sergio Romero and Huanguang Jia
    Citation: BMC Nephrology 2022 23:121
    Content type: Research Published on:

  46. Chronic kidney disease (CKD) affects 8 to 16% of the world’s population and is one of the top ten important drivers of increasing disease burden. Apart from genetic predisposition, lifestyle factors greatly co...

    Authors: Ting Yin, Yilong Chen, Lei Tang, Huaihong Yuan, Xiaoxi Zeng and Ping Fu
    Citation: BMC Nephrology 2022 23:120
    Content type: Research Published on:

  47. Hemodialysis (HD) treatment affects functioning, physical activity level, clinical biomarkers, and body composition. However, the association between these variables with functioning, considering International...

    Authors: Luciana M. M. Santos, Pedro Henrique S. Figueiredo, Ana C. R. Silva, Patrícia C. Campos, Gabriele T. Gonçalves, Jaqueline de Paula C Freitas, Fidelis Antônio da Silva Junior, Jousielle Márcia Santos, Frederico L. Alves, Vanessa G. B. Rodrigues, Emílio Henrique B. Maciel, Maria Cecília S. M. Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Vanessa P. Lima…
    Citation: BMC Nephrology 2022 23:119
    Content type: Research article Published on:

  48. IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated...

    Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Hans-Peter Marti, Frode Berven and Bjørn Egil Vikse
    Citation: BMC Nephrology 2022 23:118
    Content type: Research Published on:

  49. Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstr...

    Authors: Yingquan Xiong, Denis Delic, Shufei Zeng, Xin Chen, Chang Chu, Ahmed A. Hasan, Bernhard K. Krämer, Thomas Klein, Lianghong Yin and Berthold Hocher
    Citation: BMC Nephrology 2022 23:117
    Content type: Research Published on:
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BMC Nephrology

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