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  1. There is limited evidence on the association between short-term changes in mineral and bone disorder parameters and survival in maintenance hemodialysis patients.

    Authors: Chihiro Kato, Naohiko Fujii, Chisato Miyakoshi, Shinji Asada, Yoshihiro Onishi, Shingo Fukuma, Takanobu Nomura, Michihito Wada, Masafumi Fukagawa, Shunichi Fukuhara and Tadao Akizawa
    Citation: BMC Nephrology 2020 21:432
    Content type: Research article Published on:

  2. Anti-glomerular basement membrane disease (GBM) is an autoimmune disease caused by the deposition of circulating anti-GBM antibodies. Non-collagen region of α3 chain of type IV collagen (α3(IV)NC1) is one of t...

    Authors: Wen-jing Wang, Xiao-yu Jia, Zhao Cui, Yan Chen, Wei Wang, Jin-li Lou, Ming-hui Zhao and Sun Ying
    Citation: BMC Nephrology 2020 21:429
    Content type: Research article Published on:

  4. Fluctuations in serum phosphate levels increased mortality in end-stage renal disease patients. However, the impacts of serum phosphate changes in hospitalized patients remain unclear. This study aimed to test...

    Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Panupong Hansrivijit, Sorkko Thirunavukkarasu, Api Chewcharat, Juan Medaura, Michael A. Mao and Kianoush B. Kashani
    Citation: BMC Nephrology 2020 21:427
    Content type: Research article Published on:

  5. Bladder cancer is the most common malignant tumor of the urinary system. One of the biological characteristics of NMIBC is the high recurrence rate after surgery. The implementation of this project aimed to in...

    Authors: Zhenlong Wang, Hui Tang, Yuquan Xue, Li Xue, Hongliang Li and Tie Chong
    Citation: BMC Nephrology 2020 21:426
    Content type: Research article Published on:

  6. Chronic kidney disease has become a major health problem around the world. It displays no symptoms until the later stages. Therefore, its early detection is crucial, and a suitable intervention is necessary to...

    Authors: Haryati Anuar, Shamsul Azhar Shah, Abdul Halim Abdul Gafor and Mohd Ihsani Mahmood
    Citation: BMC Nephrology 2020 21:425
    Content type: Research article Published on:

  7. Kidney disease accounts for more than 49 billion dollars in healthcare expenditures annually. Early detection and intervention may reduce the burden of disease. We describe a quality improvement project to dev...

    Authors: Melissa L. Swee, M. Lee Sanders, Kantima Phisitkul, George Bailey, Angie Thumann, Nikki Neuzil, Bharat Kumar, Amy M. J. O’Shea and Bradley S. Dixon
    Citation: BMC Nephrology 2020 21:424
    Content type: Research article Published on:

  8. A series of policy changes in 2011 altered reimbursement arrangements and guidance on use of erythropoiesis-stimulating agents for end-stage renal disease (ESRD) patients with anaemia in the US. While the poli...

    Authors: Nga TQ. Nguyen, Alexander P. Maxwell, Michael Donnelly and Ciaran O’Neill
    Citation: BMC Nephrology 2020 21:423
    Content type: Research article Published on:

  9. Early kidney transplantation (KT) is the best option for patients with end-stage kidney disease, but little is known about dialysis access strategy in this context. We studied practice patterns of dialysis acc...

    Authors: Raphaëlle Sylvestre, Natalia Alencar de Pinho, Ziad A. Massy, Christian Jacquelinet, Mathilde Prezelin-Reydit, Roula Galland, Bénédicte Stengel and Raphael Coscas
    Citation: BMC Nephrology 2020 21:422
    Content type: Research article Published on:

  10. Patients with end-stage kidney disease, receiving haemodialysis rely increasingly on informal carers to help manage their debilitating chronic disease. Informal carers may experience a negative impact on their...

    Authors: Michael Matthews, Joanne Reid, Clare McKeaveney, Robert Mullan, Stephanie Bolton, Christopher Hill and Helen Noble
    Citation: BMC Nephrology 2020 21:421
    Content type: Study protocol Published on:

  11. People with end-stage kidney disease have an increased risk of active tuberculosis (TB). Previous systematic reviews have demonstrated that patients with chronic kidney disease (CKD) have increased risk of sev...

    Authors: Judith Ruzangi, Masao Iwagami, Liam Smeeth, Punam Mangtani and Dorothea Nitsch
    Citation: BMC Nephrology 2020 21:420
    Content type: Research article Published on:

  12. Infection with the severe acute respiratory coronavirus 2 (SARS-CoV-2) has led to a worldwide pandemic with coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2, overwhelming healthcare system...

    Authors: Samira Bell, Jacqueline Campbell, Jackie McDonald, Martin O’Neill, Chrissie Watters, Katharine Buck, Zoe Cousland, Mark Findlay, Nazir I. Lone, Wendy Metcalfe, Shona Methven, Robert Peel, Alison Almond, Vinod Sanu, Elaine Spalding, Peter C. Thomson…
    Citation: BMC Nephrology 2020 21:419
    Content type: Research article Published on:

  13. The causes of anaemia in patients with end-stage renal disease include a relative deficiency in erythropoietin production and complex clinical conditions. We aimed to investigate the underlying mechanisms of a...

    Authors: Koichiro Matsumura, Toshika Okumiya, Tetsuro Sugiura, Nobuyuki Takahashi, Yoshihiro Yamamoto, Sanae Kikuchi, Kenichi Fujii, Munemitsu Otagaki and Ichiro Shiojima
    Citation: BMC Nephrology 2020 21:418
    Content type: Research article Published on:

  14. Acute kidney injury (AKI) is increasingly recognized as a consequential clinical complication in children with severe malaria. However, approaches to estimate baseline creatinine (bSCr) are not standardized in...

    Authors: Anthony Batte, Michelle C. Starr, Andrew L. Schwaderer, Robert O. Opoka, Ruth Namazzi, Erika S. Phelps Nishiguchi, John M. Ssenkusu, Chandy C. John and Andrea L. Conroy
    Citation: BMC Nephrology 2020 21:417
    Content type: Research article Published on:

  15. Minimal change disease (MCD) is one of the causes of idiopathic nephrotic syndrome in adults. The pathogenesis of proteinuria in MCD has not been fully understood. Recently, it has been reported that the recep...

    Authors: Keisuke Horikoshi, Norihiko Sakai, Naoki Yamamoto, Hisayuki Ogura, Koichi Sato, Taro Miyagawa, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi and Takashi Wada
    Citation: BMC Nephrology 2020 21:416
    Content type: Case report Published on:

  16. Anaemia is a common presenting feature among patients with chronic kidney disease (CKD) and it is associated with poor clinical outcomes and quality of life. It is not clear if growth differentiation factor-15...

    Authors: Aishatu M. Nalado, Gbenga Olorunfemi, Therese Dix-Peek, Caroline Dickens, Lungile Khambule, Tracy Snyman, Graham Paget, Johnny Mahlangu, Raquel Duarte, Jaya George and Saraladevi Naicker
    Citation: BMC Nephrology 2020 21:415
    Content type: Research article Published on:

  17. Chronic kidney disease (CKD) patients, especially those with end stage renal disease (ESRD) undergoing hemodialysis (HD), exhibit high prevalence of periodontitis. This cross-sectional study aimed to investiga...

    Authors: Xiaobo Duan, Xiaolei Chen, Megha Gupta, Dutmanee Seriwatanachai, Hanxiao Xue, Qiuchan Xiong, Tong Xu, Dan Li, Anchun Mo, Xi Tang, Xuedong Zhou, Yuqing Li and Quan Yuan
    Citation: BMC Nephrology 2020 21:414
    Content type: Research article Published on:

  18. Cardiovascular disease is the most common cause of death in patients with end-stage kidney disease on haemodialysis. The potential clinical consequence of systematic echocardiographic assessment is however not...

    Authors: Anna Axelsson Raja, Peder E. Warming, Ture L. Nielsen, Louis L. Plesner, Mads Ersbøll, Morten Dalsgaard, Morten Schou, Casper Rydahl, Lisbet Brandi and Kasper Iversen
    Citation: BMC Nephrology 2020 21:413
    Content type: Research article Published on:

  19. Acute kidney injury (AKI) is defined as a sudden event of kidney failure or kidney damage within a short period. Ischemia-reperfusion injury (IRI) is a critical factor associated with severe AKI and end-stage ...

    Authors: Meeyoung Park, Chae Hwa Kwon, Hong Koo Ha, Miyeun Han and Sang Heon Song
    Citation: BMC Nephrology 2020 21(Suppl 1):398
    Content type: Research Published on:

    This article is part of a Supplement: Volume 21 Supplement 1

  20. The optimal choice of treatment, with hemodialysis (HD) or peritoneal dialysis (PD), for end-stage renal disease (ESRD) patients, is still controversial. Only a few studies comparing HD and PD have been conduc...

    Authors: Zhiren He, Haijing Hou, Difei Zhang, Yenan Mo, La Zhang, Guobin Su, Junjie Lin, Liming Lu, Jingyao Huang, Yewen Gu, Ying Zhang, Jingxia Lin, Fengling Yuan, Yu Peng, Hui Liang, Daixin Zhao…
    Citation: BMC Nephrology 2020 21:412
    Content type: Research article Published on:

  21. Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in ...

    Authors: A. C. Nixon, T. J. Wilkinson, H.M.L. Young, M. W. Taal, N. Pendleton, S. Mitra, M. E. Brady, A. P. Dhaygude and A. C. Smith
    Citation: BMC Nephrology 2020 21:411
    Content type: Research article Published on:

  22. Concurrent type 1 diabetes mellitus (T1DM) and idiopathic nephrotic syndrome is rare, and most previously reported cases were in children. We report the case of an adult woman who developed T1DM and minimal ch...

    Authors: Ryuzoh Nishizono, Hiroki Kogou, Yuri Ishizaki, Akihiro Minakawa, Masao Kikuchi, Hiroko Inagaki, Yuji Sato and Shouichi Fujimoto
    Citation: BMC Nephrology 2020 21:410
    Content type: Case report Published on:

  23. This scoping review sought to summarize available data on the prevalence, associated factors, etiology, comorbidities, treatment, cost and mortality of chronic kidney disease (CKD) in Cameroon.

    Authors: Jerry Brown Aseneh, Ben-Lawrence A. Kemah, Stephane Mabouna, Mbeng Emmanuel Njang, Domin Sone Majunda Ekane and Valirie Ndip Agbor
    Citation: BMC Nephrology 2020 21:409
    Content type: Review Published on:

  24. Autosomal dominant polycystic kidney disease (ADPKD), the predominant type of inherited kidney disorder, occurs due to PKD1 and PKD2 gene mutations. ADPKD diagnosis is made primarily by kidney imaging. However, m...

    Authors: Fatemeh Khadangi, Adam Torkamanzehi and Mohammad Amin Kerachian
    Citation: BMC Nephrology 2020 21:408
    Content type: Research article Published on:

  25. The epidemiology of dialysis patients has been little studied in developing countries and economies in transition. We examined the prevalence, incidence and mortality rate of dialysis patients in Kazakhstan, v...

    Authors: Abduzhappar Gaipov, Alpamys Issanov, Kainar Kadyrzhanuly, Dinara Galiyeva, Marina Khvan, Mohamad Aljofan, Miklos Z. Molnar and Csaba P. Kovesdy
    Citation: BMC Nephrology 2020 21:407
    Content type: Research article Published on:

  26. Herein, a 3-year-old boy presented with hidden-onset isolated proteinuria was reported. The disease was induced by COQ8B (previously termed ADCK4) compound heterozygous variants, including c.[271C > T] and c.[737...

    Authors: Shu-bo Zhai, Li Zhang, Bai-chao Sun, Yan Zhang and Qing-shan Ma
    Citation: BMC Nephrology 2020 21:406
    Content type: Case report Published on:

  27. We here report on the first observation of a C3 mutation that is related to atypical hemolytic and uremic syndrome (aHUS), which occurred in a pancreatic islet transplant patient. Immunosuppressive treatments,...

    Authors: Thibault Bahougne, Jérome Olagne, Marion Munch, Laura Braun-Parvez, Marie-Pierrette Chenard, Véronique Frémeaux-Bacchi, Sophie Caillard, Philippe Baltzinger, Michel Greget, Laurence Kessler and Bruno Moulin
    Citation: BMC Nephrology 2020 21:405
    Content type: Case report Published on:

  28. Peritoneal dialysis (PD)-related peritonitis is a rare but serious complication and is associated with increased morbidity and mortality rates. It is most commonly caused by Staphylococcus aureus or Staphylococcu...

    Authors: Kristina Boss, Ina Wiegard-Szramek, Jan Dziobaka, Andreas Kribben and Sebastian Dolff
    Citation: BMC Nephrology 2020 21:404
    Content type: Case report Published on:

  29. Calciphylaxis is a rare condition usually seen in patients with end-stage renal disease. Pain is a hallmark of this condition and can be extremely difficult to control. Anecdotal data suggests that pain manage...

    Authors: Rajkumar Chinnadurai, Smeeta Sinha, Aoife C Lowney and Mary Miller
    Citation: BMC Nephrology 2020 21:403
    Content type: Research article Published on:

  30. Dipeptidyl peptidase-4 (DPP-4) is a serine protease that inhibits the degradation of glucagon-like peptide 1. DPP-4 inhibitors are used worldwide to treat type 2 diabetes mellitus and were recently shown to ha...

    Authors: Ayano Kubo, Teruo Hidaka, Maiko Nakayama, Yu Sasaki, Miyuki Takagi, Hitoshi Suzuki and Yusuke Suzuki
    Citation: BMC Nephrology 2020 21:402
    Content type: Research article Published on:

  31. Membranous nephropathy (MN) has been recognized to occur in patients with human immunodeficiency virus (HIV) infection since the beginning of the HIV epidemic. The prevalence of phospholipase A2 receptor (PLA2...

    Authors: Vivek Charu, Nicole Andeen, Vighnesh Walavalkar, Jessica Lapasia, Jin-Yon Kim, Andrew Lin, Richard Sibley, John Higgins, Megan Troxell and Neeraja Kambham
    Citation: BMC Nephrology 2020 21:401
    Content type: Research article Published on:

  32. C3-glomerulonephritis can lead to progressive renal impairment from complement-mediated glomerular injury. Incidence and outcomes of C3-glomerulonephritis are not known in the New Zealand population.

    Authors: Luke J. Sutherland and Hari Talreja
    Citation: BMC Nephrology 2020 21:399
    Content type: Research article Published on:

  33. Fungal peritonitis (FP) is an infrequent but serious complication in children undergoing peritoneal dialysis (PD). This study aimed to explore the risk factors, clinical manifestations, causative organisms, fu...

    Authors: Mohammed Alsuhaibani, Egab Aldosari, Khawla A. Rahim, Saeed Alzabli and Dayel Alshahrani
    Citation: BMC Nephrology 2020 21:400
    Content type: Research article Published on:

  34. We aimed to examine the risk factors for chronic kidney disease (CKD) stage 3 among adults with ASK from unilateral nephrectomy.

    Authors: Wen-Jun Zhang, Zi-Yi Wang, Wei-Xing Zhou, Ning-Qiang Yang, Ya Wang, Ya Tang, Xiao-Chun Zhou, Jie-Cao Dao, Yan-Ru Ma, Yan-Ping He, Xiao-Ling Wang, Wen-Ge Wang and Li Yang
    Citation: BMC Nephrology 2020 21:397
    Content type: Research article Published on:

  35. Minimal change disease (MCD) is one of the major causes of nephrotic syndrome (NS). A confirmed MCD diagnosis mainly depends on renal biopsy at present, which is an invasive procedure with many potential risks...

    Authors: Gaofei Yan, Guanzhi Liu, Xuefei Tian, Lifang Tian, Hao Wang, Peiyao Ren, Xiaotao Ma, Rongguo Fu and Zhao Chen
    Citation: BMC Nephrology 2020 21:396
    Content type: Technical advance Published on:

  36. Cryoglobulinemic glomerulonephritis (CryoGn) caused by hepatitis B virus (HBV) infection was rarely reported. Our study aimed to investigate the clinical features, renal pathology findings, and prognosis in pa...

    Authors: Chao Li, Hang Li, Wei Su, Yu-bing Wen, Wei Ye, Wen-ling Ye, Jian-fang Cai, Xu-zhen Qin, Xue-mei Li and Xue-wang Li
    Citation: BMC Nephrology 2020 21:395
    Content type: Research article Published on:

  37. Platelet activation is an important side effect of dialysis, resulted in a subsequent release of arachidonic acid (AA) from activated platelets. AA is involved in many pathologic conditions, such as inflammati...

    Authors: Elżbieta Cecerska-Heryć, Rafał Heryć, Magda Wiśniewska, Natalia Serwin, Bartłomiej Grygorcewicz and Barbara Dołęgowska
    Citation: BMC Nephrology 2020 21:394
    Content type: Research article Published on:

  38. Hyponatremia is known to be associated with a worse patient outcome in heart failure. In cardiorenal syndrome (CRS), the prognostic role of concomitant hyponatremia is unclear. We sought to evaluate potential ...

    Authors: Rainer U. Pliquett, Katrin Schlump, Andreas Wienke, Babett Bartling, Michel Noutsias, Alexander Tamm and Matthias Girndt
    Citation: BMC Nephrology 2020 21:393
    Content type: Research article Published on:

  40. Immune checkpoint inhibitors (ICI) have become the standard of care in many oncological conditions but are associated with a spectrum of renal immune-related adverse events (IrAEs). We aimed to describe the sp...

    Authors: Sebastian Hultin, Kazi Nahar, Alexander M. Menzies, Georgina V. Long, Suran L. Fernando, Victoria Atkinson, Jonathan Cebon and Muh Geot Wong
    Citation: BMC Nephrology 2020 21:391
    Content type: Research article Published on:

  42. Serum neutrophil gelatinase-associated lipocalin (NGAL) could be used as a predictive marker of acute kidney injury (AKI) in patients with return of spontaneous circulation (ROSC) after out-of-hospital cardiac...

    Authors: Yoon Hee Choi, Dong Hoon Lee and Jae Hee Lee
    Citation: BMC Nephrology 2020 21:389
    Content type: Research article Published on:

  43. New-onset diabetes after transplantation (NODAT) is associated with reduced patient and graft survival. This study examined the clinical and selected genetic factors associated with NODAT among renal-transplan...

    Authors: Rhanye Mac Guad, Andrew W. Taylor-Robinson, Yuan Seng Wu, Siew Hua Gan, Nur Lisa Zaharan, Roma Choudhury Basu, Constance Sat Lin Liew and Wan Ahmad Hafiz Wan Md Adnan
    Citation: BMC Nephrology 2020 21:388
    Content type: Research article Published on:

  44. An epidemic of chronic kidney disease of unknown cause (CKDu) is occurring in rural communities in tropical regions of low-and middle-income countries in South America and India. Little information is availabl...

    Authors: Sophie A. Hamilton, Wisdom P. Nakanga, Josephine E. Prynn, Amelia C. Crampin, Daniela Fecht, Paolo Vineis, Ben Caplin, Neil Pearce and Moffat J. Nyirenda
    Citation: BMC Nephrology 2020 21:387
    Content type: Research article Published on:

  45. The association between lower serum sodium levels and the clinical outcomes of insomnia patients remains unclear. We explored whether lower serum sodium is associated with poor clinical outcomes in patients wi...

    Authors: Eunjin Bae, Tae Won Lee, Ha Nee Jang, Hyun Seop Cho, Sehyun Jung, Seunghye Lee, Se-Ho Chang and Dong Jun Park
    Citation: BMC Nephrology 2020 21:386
    Content type: Research article Published on:

  46. Excess cadmium (Cd) intake poses a general risk to health and to the kidneys in particular. Among indices of renal dysfunction under Cd burden measures are the urinary N-acetyl-β-D-glucosidase (UNAG) and urina...

    Authors: Yuting Li, Hongmei Wang, Jie Yu, Qiong Yan, Honggang Hu, Lishu Zhang, Tian Tian, Xianglei Peng, Shuo Yang and Shen Ke
    Citation: BMC Nephrology 2020 21:385
    Content type: Research article Published on:

  47. This article describes the analysis and interpretation of data relating to the presence of cadmium, lead, mercury and fluoride in human bone samples obtained from cadavers of patients dying of Chronic Kidney D...

    Authors: Thalarabe Bulathge Ananda Jayalal, Sanath Thushara Chamakara Mahawithanage, Senanayaka Mudiyanselage Harshana Mahendra Kumara Senanayaka and Prasanna Bandara Dassanayaka
    Citation: BMC Nephrology 2020 21:384
    Content type: Research article Published on:

  48. Kidney disease and dialysis significantly impact cognitive function across the age spectrum. Cognitive training (CT) and/or exercise training (ET) are promising approaches to preserve cognitive function among ...

    Authors: Mara A. McAdams-DeMarco, Nadia M. Chu, Malu Steckel, Sneha Kunwar, Marlís González Fernández, Michelle C. Carlson, Derek M. Fine, Lawrence J. Appel, Marie Diener-West and Dorry L. Segev
    Citation: BMC Nephrology 2020 21:383
    Content type: Study protocol Published on:

  49. Previous studies have identified retinal microvascular features associated with renal dysfunction. Biopsies are necessary to confirm kidney microvascular damage and retinal imaging may enable evaluation of mic...

    Authors: R. A. O’Neill, A. P. Maxwell, F. Kee, I. Young, B. McGuinness, R. E. Hogg and McKay GJ
    Citation: BMC Nephrology 2020 21:382
    Content type: Research article Published on:

  50. Acute kidney injury (AKI) often occurs in critically ill patients. AKI is associated with mortality and morbidity. Interventions focusing on the reduction of AKI are suggested by the Kidney Disease: Improving ...

    Authors: Jacqueline Koeze, Iwan C. C. van der Horst, Renske Wiersema, Frederik Keus, Willem Dieperink, Eline G. M. Cox, Jan G. Zijlstra and Matijs van Meurs
    Citation: BMC Nephrology 2020 21:381
    Content type: Research article Published on:
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