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  1. Use of rituximab (RTX) for focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) is widely described in children. Clinical evidence in adults is limited. The objective of this study was to...

    Authors: Panupong Hansrivijit, Wisit Cheungpasitporn, Charat Thongprayoon and Nasrollah Ghahramani
    Citation: BMC Nephrology 2020 21:134
    Content type: Research article Published on:

  3. Diabetic nephropathy (DN) is the most prevalent cause of renal disease in type 2 diabetic patients and is usually diagnosed clinically. A kidney biopsy is considered when non-diabetic renal disease (NDRD) is s...

    Authors: Jyh-Tong Hsieh, Fu-Pang Chang, An-Hang Yang, Der-Cherng Tarng and Chih-Yu Yang
    Citation: BMC Nephrology 2020 21:131
    Content type: Research article Published on:

  4. Optimal clinical care of patients with chronic kidney disease (CKD) requires collaboration between primary care physicians (PCPs) and nephrologists. We undertook a randomised trial to determine the impact of s...

    Authors: Patrick Saudan, Belen Ponte, Nicola Marangon, Chantal Martinez, Lena Berchtold, David Jaques, Thomas Ernandez, Sophie de Seigneux, Sebastian Carballo, Thomas Perneger and Pierre-Yves Martin
    Citation: BMC Nephrology 2020 21:128
    Content type: Research article Published on:

  5. Vibrio vulnificus infection is a rare but fatal foodborne illness. Here, we report a case of Vibrio vulnificus peritonitis followed by severe septicemia in a patient undergoing continuous ambulatory peritoneal di...

    Authors: Jae Young Kim, Young Su Joo, Sangmi Lee, Ji Young Lee, Jung Tak Park, Seong Hyeok Han, Tae-Hyun Yoo and Shin-Wook Kang
    Citation: BMC Nephrology 2020 21:127
    Content type: Case report Published on:

  6. The prevalence of impaired cognitive functioning in older patients with end stage kidney disease (ESKD) is high. We aim to describe patterns of memory, executive function or psychomotor speed and to identify n...

    Authors: Floor J. van Deudekom, Marije H. Kallenberg, Noeleen C. Berkhout-Byrne, Gerard J. Blauw, Henk Boom, Jeroen de Bresser, Mark A. van Buchem, André Gaasbeek, Sebastiaan Hammer, Joep Lagro, Matthias J. P. van Osch, Marie-Noëlle Witjes-Ané, Ton J. Rabelink, Marjolijn van Buren and Simon P. Mooijaart
    Citation: BMC Nephrology 2020 21:126
    Content type: Research article Published on:

  7. Idiopathic nephrotic syndrome has a relapsing-remitting course in the majority of pediatric patients, demanding vigilant monitoring and self-management. A novel, expert-designed, user-informed mobile applicati...

    Authors: Chia-shi Wang, Cam Escoffery, Rachel E. Patzer, Courtney McCracken, Diana Ross, Michelle N. Rheault, Amira Al-Uzri and Larry A. Greenbaum
    Citation: BMC Nephrology 2020 21:125
    Content type: Study protocol Published on:

  8. Although the prevalence of kidney disease is higher in those with reduced lung function, the longitudinal relationship between low lung function and future risk of chronic kidney disease (CKD) has not been wid...

    Authors: Suneela Zaigham, Anders Christensson, Per Wollmer and Gunnar Engström
    Citation: BMC Nephrology 2020 21:124
    Content type: Research article Published on:

  9. The renal length and cortical echogenicity have shown correlation to the renal function and histological changes in CKD patients. The aim of this study was to assess the accuracy of crude and composite ultraso...

    Authors: Nordeval Cavalcante Araújo, Maria Alice Puga Rebelo, Lilimar da Silveira Rioja and José Hermógenes Rocco Suassuna
    Citation: BMC Nephrology 2020 21:123
    Content type: Research article Published on:

  10. Increased leucine-rich α2-glycoprotein-1 (LRG1) has been observed in various inflammatory and autoimmune diseases. We aimed to explore the expression and role of LRG1 in lupus nephritis (LN).

    Authors: Yi Yang, Ran Luo, Yichun Cheng, Tingting Liu, Wei Dai, Yueqiang Li, Shuwang Ge and Gang Xu
    Citation: BMC Nephrology 2020 21:122
    Content type: Research article Published on:

  11. Vascular calcification progression has been associated with the loss of trabecular bone in chronic kidney disease (CKD) patients. There are few data evaluating the relationship between cortical bone loss and v...

    Authors: Larissa R. Costa, Aluizio B. Carvalho, Amandha L. Bittencourt, Carlos E. Rochitte and Maria Eugênia F. Canziani
    Citation: BMC Nephrology 2020 21:121
    Content type: Research article Published on:

  12. Few chronic kidney disease (CKD) risk prediction models have been investigated in low- and middle-income areas worldwide. We developed new risk scores for predicting incident CKD in low- and middle-income rura...

    Authors: Jiangping Wen, Jie Hao, Ye Zhang, Kai Cao, Xiaohong Zhang, Jiang Li, Xinxin Lu and Ningli Wang
    Citation: BMC Nephrology 2020 21:120
    Content type: Research article Published on:

  13. Increased urinary albumin excretion (UAE) in diabetes is a sensitive marker of microvascular injury and a reliable predictor of cardiovascular outcomes. Hypertension-induced hemodynamic pressure load, diabetes...

    Authors: Barbara Nikolaidou, Eugenia Gkaliagkousi, Panagiota Anyfanti, Eleni Gavriilaki, Antonios Lazaridis, Areti Triantafyllou, Ioanna Zografou and Stella Douma
    Citation: BMC Nephrology 2020 21:119
    Content type: Research article Published on:

  14. (1–3)-β-D glucans (BG) are cellular components of yeasts and fungi. Elevated blood levels may be an adjunct in diagnosing invasive fungal infection, though can be high in dialysis patients without fungaemia. B...

    Authors: Jonathan Wong, Yonglong Zhang, Oscar Swift, Malcolm Finkelman, Ashish Patidar, Sivaramakrishnan Ramanarayanan, Enric Vilar and Ken Farrington
    Citation: BMC Nephrology 2020 21:118
    Content type: Research article Published on:

  15. In the past urine was considered sterile. Through the introduction of next generation sequencing, it has become clear that a urinary microbiome exists. Acute kidney injury (AKI) represents a major threat to ki...

    Authors: Daniela Gerges-Knafl, Peter Pichler, Alexander Zimprich, Christoph Hotzy, Wolfgang Barousch, Rita M. Lang, Elisabeth Lobmeyr, Sabina Baumgartner-Parzer, Ludwig Wagner and Wolfgang Winnicki
    Citation: BMC Nephrology 2020 21:117
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Nephrology 2020 21:168

  16. Little is known about the relationship between acute kidney injury (AKI) and outcomes after acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We aimed to investigate associations between AK...

    Authors: Atsushi Hirayama, Tadahiro Goto and Kohei Hasegawa
    Citation: BMC Nephrology 2020 21:116
    Content type: Research article Published on:

  17. This study was conducted to evaluate and update the current prevalence of and risk factors for chronic kidney disease (CKD) and diabetic kidney disease (DKD) in a central Chinese urban population.

    Authors: Jia-Yu Duan, Guang-Cai Duan, Chong-Jian Wang, Dong-Wei Liu, Ying-Jin Qiao, Shao-Kang Pan, Deng-Ke Jiang, Yong Liu, Zi-Hao Zhao, Lu-Lu Liang, Fei Tian and Zhang-Suo Liu
    Citation: BMC Nephrology 2020 21:115
    Content type: Research article Published on:

  18. Non-adherence (NA) to immunosuppressants (IS) among renal transplant recipients (RTRs) is associated with higher risk of allograft rejection, graft loss, and mortality. A precise measurement of NA is indispens...

    Authors: Marietta Lieb, Tobias Hepp, Mario Schiffer, Mirian Opgenoorth and Yesim Erim
    Citation: BMC Nephrology 2020 21:114
    Content type: Research article Published on:

  19. The advent of immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of patients with advanced malignancies. On the other hand, these drugs might cause immune-related adverse events (irAE...

    Authors: Natsumi Matsuoka, Kenji Tsuji, Eiki Ichihara, Takayuki Hara, Kazuhiko Fukushima, Kishio Toma, Shinji Kitamura, Kenichi Inagaki, Hitoshi Sugiyama and Jun Wada
    Citation: BMC Nephrology 2020 21:113
    Content type: Case report Published on:

  20. The purse-string suture has been widely used for bleeding control after percutaneous interventions through arteriovenous fistula (AVF) and graft (AVG), and it requires suture removal the next day. This study a...

    Authors: Qiquan Lai, Hui Zhang, Bo Chen, Xuejing Gao, Ling Chen, Bo Tu, Baifei Li, Bo Hu, Fan He, Yong Xu and Ziming Wan
    Citation: BMC Nephrology 2020 21:112
    Content type: Research article Published on:

  21. Monoclonal serum free light chains (sFLC) are a well-known cause of renal impairment (RI) in patients with multiple myeloma (MM). As an indicator of monoclonality, sFLC ratio has acquired a key role in the dia...

    Authors: Alícia Molina-Andújar, Pau Robles, Maria T. Cibeira, Enrique Montagud-Marrahi, Elena Guillen, Marc Xipell, Miquel Blasco, Esteban Poch, Laura Rosiñol, Joan Bladé and Luis F. Quintana
    Citation: BMC Nephrology 2020 21:111
    Content type: Research article Published on:

  22. Encapsulating-peritoneal-sclerosis (EPS) is a rare, but serious and life-threatening complication of peritoneal dialysis (PD). Treatment of EPS consists of discontinuation of PD and maintenance of nutritional ...

    Authors: Vassilios Liakopoulos, Panagiotis I. Georgianos, Vasilios Vaios, Stefanos Roumeliotis, Apostolos Karligkiotis and Pantelis E. Zebekakis
    Citation: BMC Nephrology 2020 21:110
    Content type: Case report Published on:

  23. Human leukocyte antigen (HLA)-G is a non-classical HLA molecule with immunomodulant and immunosuppressive functions, involved in transplantation tolerance. HLA-G14bp ins/del polymorphism in exon 8 has been ass...

    Authors: Daniela Piancatelli, Daniela Maccarone, Alessia Colanardi, Pierluigi Sebastiani, Katia Clemente, Samuele Iesari, Quirino Lai and Francesco Pisani
    Citation: BMC Nephrology 2020 21:109
    Content type: Research article Published on:

  24. Prior papers have been inconsistent regarding how much creatinine clearance (CrCl) overestimates glomerular filtration rate (GFR). A recent cross-sectional study suggested that measurement error alone could en...

    Authors: Xuehan Zhang, Andrew D. Rule, Charles E. McCulloch, John C. Lieske, Elaine Ku and Chi-yuan Hsu
    Citation: BMC Nephrology 2020 21:108
    Content type: Research article Published on:

  25. The conjunction of hepatitis and renal disease can be seen in several clinical context, including karyomegalic nephritis (KIN). Karyomegalic nephritis (KIN) is a rare genetic disease, with less than 50 cases r...

    Authors: Jonathan Dash, Patrick Saudan, Ariane Paoloni-Giacobino, Solange Moll and Sophie de Seigneux
    Citation: BMC Nephrology 2020 21:107
    Content type: Case report Published on:

  27. Following publication of the original article [1], we have been notified that the approved number by the Ethical Committee was given incorrectly. In the section “Methods” stated that: The Central Ethical Commi...

    Authors: Rita Jacobs, Patrick M. Honore, Marc Diltoer and Herbert D. Spapen
    Citation: BMC Nephrology 2020 21:105
    Content type: Correction Published on:

    The original article was published in BMC Nephrology 2016 17:119

  28. Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by systemic thrombotic microangiopathy (TMA) reflected by hemolysis, anemia, thrombocytopenia and systemic organ injury. The optimal ma...

    Authors: Christoph Nunius, Maike Büttner-Herold, Simone Bertz, Mario Schiffer and Bjoern Buchholz
    Citation: BMC Nephrology 2020 21:104
    Content type: Case report Published on:

  29. High water hardness associated with high water fluoride and the geographical distribution of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka are well correlated. We undertook this study to obser...

    Authors: Thanusha Perera, Shirani Ranasinghe, Neil Alles and Roshitha Waduge
    Citation: BMC Nephrology 2020 21:103
    Content type: Research article Published on:

  30. P. multocida (Pasteurella multocida) is animal-sourced gram-negative coccobacillus which can be transmitted to human through many animals including household pets. P. multocida induced peritoneal dialysis-related...

    Authors: Haoran Mu, Man Yang, Yueyue Zhang, Yajing Zhang, Juan Wang, Weijie Yuan and Shu Rong
    Citation: BMC Nephrology 2020 21:102
    Content type: Case report Published on:

  31. Little is known about the changes in disease makers and risk factors in patients with chronic kidney disease (CKD) under nephrological care in Africa. This study aimed to evaluate the baseline level of markers...

    Authors: Halle Marie Patrice, Kengne Andre Pascal, Kaze Folefack François, Djantio Hilaire, Doualla Marie Solange, Ashuntantang Enow Gloria and Choukem Siméon Pierre
    Citation: BMC Nephrology 2020 21:101
    Content type: Research article Published on:

  32. A randomized trial of a pedometer-based intervention with weekly activity goals led to a modest increase in step count among dialysis patients. In a secondary analysis, we investigated the effect of this inter...

    Authors: Anoop Sheshadri, Piyawan Kittiskulnam, Jennifer C. Lai and Kirsten L. Johansen
    Citation: BMC Nephrology 2020 21:100
    Content type: Research article Published on:

  33. Stage 5 chronic kidney disease (CKD-5) patients on haemodialysis (HD) are at high risk of accidental falls. Previous research has shown that frailty is one of the primary contributors to the increased risk of ...

    Authors: Tobia Zanotto, Thomas H. Mercer, Marietta L. van der Linden, Robert Rush, Jamie P. Traynor, Colin J. Petrie, Arthur Doyle, Karen Chalmers, Nicola Allan, Ilona Shilliday and Pelagia Koufaki
    Citation: BMC Nephrology 2020 21:99
    Content type: Research article Published on:

  34. Acute kidney injury (AKI) is highly associated with mortality risk in children worldwide. Trauma can lead to AKI and is a leading cause of pediatric death in Africa. However, there is no information regarding ...

    Authors: Erica C. Bjornstad, William Muronya, Zachary H. Smith, Keisha Gibson, Amy K. Mottl, Anthony Charles, Stephen W. Marshall, Yvonne M. Golightly, Charles K. Munthali and Emily W. Gower
    Citation: BMC Nephrology 2020 21:98
    Content type: Research article Published on:

  35. Growing evidence has shown that the gut-renal connection and gut microbiota dysbiosis play a critical role in immunoglobulin A nephropathy (IgAN). However, the fecal microbiome profile in Chinese patients with...

    Authors: Xiaofang Hu, Jie Du, Yuhong Xie, Qiong Huang, Yi Xiao, Juan Chen, Siyuan Yan, Zhicheng Gong and Shaxi Ouyang
    Citation: BMC Nephrology 2020 21:97
    Content type: Research article Published on:

  36. Thrombotic microangiopathy (TMA) syndromes are characterized by the association of hemolytic anemia, thrombocytopenia and organ injury due to arteriolar and capillary thrombosis.

    Authors: C. Philipponnet, J. Desenclos, M. Brailova, J. Aniort, J. L. Kemeny, C. Deville, V. Fremeaux-Bacchi, B. Souweine and A. E. Heng
    Citation: BMC Nephrology 2020 21:96
    Content type: Case report Published on:

  37. Chronic kidney disease (CKD) is growing population health concern worldwide, and with early identification and effective management, kidney disease progression can be slowed or prevented. Most patients with ri...

    Authors: Elizabeth P. Neale, Justin Middleton and Kelly Lambert
    Citation: BMC Nephrology 2020 21:83
    Content type: Research article Published on:

  38. Acute kidney injury (AKI) is a common complication among human immunodeficiency virus (HIV)-infected patients resulting in increased morbidity and mortality. Continuous renal replacement therapy (CRRT) is a us...

    Authors: Hebing Guo, Jingyuan Liu, Lin Pu, Jingjing Hao, Ningning Yin, Yufeng Liu, Haofeng Xiong and Ang Li
    Citation: BMC Nephrology 2020 21:95
    Content type: Research article Published on:

  39. In low-middle-income countries (LMICs), data regarding acute kidney injury (AKI) are scarce. AKI patients experience delayed diagnosis. This study aimed to evaluate whether delayed nephrologist consultation (N...

    Authors: Ginivaldo Victor Ribeiro do Nascimento, Marcela do Nascimento Silva, Juarez Duarte de Carvalho Neto, Ludgero Ribeiro Feitosa Filho and Jessica Duarte Antão
    Citation: BMC Nephrology 2020 21:94
    Content type: Research article Published on:

  40. Pneumocystis pneumonia (PCP) is a life-threatening fungal infection that can occur in kidney transplantation (KT) recipients. A growing number of KT recipients are receiving perioperative treatment with rituxi...

    Authors: Young Hoon Kim, Jee Yeon Kim, Dong Hyun Kim, Youngmin Ko, Ji Yoon Choi, Sung Shin, Joo Hee Jung, Su-Kil Park, Sung-Han Kim, Hyunwook Kwon and Duck Jong Han
    Citation: BMC Nephrology 2020 21:93
    Content type: Research article Published on:

  41. The efficacy and safety of minimisation of immunosuppression including early steroid withdrawal in kidney transplant recipients treated with Basiliximab induction remains unclear.

    Authors: Mysore K. Phanish, Richard P. Hull, Peter A. Andrews, Joyce Popoola, Edward J. Kingdon and Iain A. M. MacPhee
    Citation: BMC Nephrology 2020 21:92
    Content type: Research article Published on:

  42. Nutritional factors are associated with high mortality and morbidity in dialysis patients, and protein-energy wasting is regarded as an important one. The modality of dialysis may affect patients’ dietary beha...

    Authors: Seon-Mi Kim, Byung Chin Kang, Hyun-Jung Kim, Min-Sook Kyung, Hyung Jung Oh, Jung-Hyun Kim, Oran Kwon and Dong-Ryeol Ryu
    Citation: BMC Nephrology 2020 21:91
    Content type: Research article Published on:

  43. DD was found to be associated with acute myocardial infarction (AMI) and renal insufficiency. However, it is uncertain whether DD is an independent risk factor of CI-AKI in patients undergoing pPCI.

    Authors: Kai-Yang Lin, Han-Chuan Chen, Hui Jiang, Sun-Ying Wang, Hong-Mei Chen, Zhi-Yong Wu, Feng Jiang, Yan-Song Guo and Peng-Li Zhu
    Citation: BMC Nephrology 2020 21:90
    Content type: Research article Published on:

  44. Left ventricular (LV) myocardial longitudinal diastolic strain rate measured by two-dimensional speckle tracking imaging (2D-STI) was proved to have a better correlation with the LV diastolic function. We aime...

    Authors: Jing Zhu, Fei Shi, Tao You, Chao Tang and Jianchang Chen
    Citation: BMC Nephrology 2020 21:89
    Content type: Research article Published on:

  45. Reductions in health-related quality of life (HRQoL) in patients with chronic kidney disease (CKD) are thought to be exacerbated by the low hemoglobin (Hb) levels that define anemia, a common complication of C...

    Authors: Heleen van Haalen, James Jackson, Bruce Spinowitz, Gary Milligan and Rebecca Moon
    Citation: BMC Nephrology 2020 21:88
    Content type: Research article Published on:

  46. Interstitial fibrosis (IF) on kidney biopsy is one of the most potent risk factors for kidney disease progression. The furosemide stress test (FST) is a validated tool that predicts the severity of acute kidne...

    Authors: Jesús Rivero, Francisco Rodríguez, Virgilia Soto, Etienne Macedo, Lakhmir S. Chawla, Ravindra L. Mehta, Sucheta Vaingankar, Pranav S. Garimella, Carlos Garza and Magdalena Madero
    Citation: BMC Nephrology 2020 21:87
    Content type: Research article Published on:

  47. Vascular calcification (VC) is a risk factor for cardiovascular disease in end-stage renal disease (ESRD) patients undergoing maintenance haemodialysis (MHD). However, evidence is still insufficient about the ...

    Authors: Sung Keun Park, Won Joong Kim, Hyun Jin Kim, Hae Won Kim, Beom Kim, Hong Joo Lee, So-Young Lee, Yu Ho Lee, Dong-Jin Kim, Kyung-Hwan Jeong, Ju-Young Moon, Sang-Ho Lee, Shin Young Ahn, Gang Jee Ko, Jae-Hong Ryoo and Dong-Young Lee
    Citation: BMC Nephrology 2020 21:86
    Content type: Research article Published on:

  48. Chronic kidney disease (CKD) has been identified as a significant direct marker for cognitive decline, but controversy exists regarding the magnitude of the association of kidney function with cognitive declin...

    Authors: Laurien E. Zijlstra, Stella Trompet, Simon P. Mooijaart, Marjolijn van Buren, Naveed Sattar, David J. Stott and J. Wouter Jukema
    Citation: BMC Nephrology 2020 21:81
    Content type: Research article Published on:

  50. Initial presentation of peritoneal dialysis associated infectious peritonitis can be clinically indistinguishable from Clostridioides difficile infection (CDI) and both may demonstrate a cloudy dialysate. Empiric...

    Authors: Kairav J. Shah, Kartikeya Cherabuddi, Kalynn B. Pressly, Kaitlyn L. Wright and Ashutosh Shukla
    Citation: BMC Nephrology 2020 21:76
    Content type: Case report Published on:
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