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  1. A low FT3 level is significantly associated with a variety of kidney disease and acute myocardial infarction (AMI). However, it remains unclear whether low FT3 is associated with CI-AKI in patients who underwe...

    Authors: Kai-Yang Lin, Sun-Ying Wang, Hui Jiang, Han-Chuan Chen, Zhi-Yong Wu, Yan-Song Guo and Peng-Li Zhu
    Citation: BMC Nephrology 2019 20:201
    Content type: Research article Published on:

  2. Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop...

    Authors: F. H. Mose, A. N. Jörgensen, M. H. Vrist, N. P. Ekelöf, E. B. Pedersen and J. N. Bech
    Citation: BMC Nephrology 2019 20:200
    Content type: Research article Published on:

  3. Due to rising vascular comorbidities of patients undergoing dialysis, the prevalence of permanent hemodialysis catheters as hemodialysis access is increasing. However, infection is a major complication of thes...

    Authors: Fani Delistefani, Manuel Wallbach, Gerhard A. Müller, Michael J. Koziolek and Clemens Grupp
    Citation: BMC Nephrology 2019 20:199
    Content type: Research article Published on:

  4. Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal ...

    Authors: Dorna Davani-Davari, Iman Karimzadeh and Hossein Khalili
    Citation: BMC Nephrology 2019 20:198
    Content type: Research article Published on:

  5. Successful vascular access (VA) cannulation is integral to the delivery of adequate dialysis, highlighting the importance of ensuring the viability of arteriovenous access in hemodialysis (HD) patients. Missed...

    Authors: Linda L. Coventry, Jon M. Hosking, Doris T. Chan, Evelyn Coral, Wai H. Lim, Amanda Towell-Barnard, Diane E. Twigg and Claire M. Rickard
    Citation: BMC Nephrology 2019 20:197
    Content type: Research article Published on:

  6. Gait speed (GS) and handgrip strength (HGS), both factors associated with frailty and sarcopenia, are reportedly associated with CV events in the general population. However, little is known about the impact o...

    Authors: Atsumi Kuki, Kentaro Tanaka, Akifumi Kushiyama, Yoshihide Tanaka, Shuta Motonishi, Yasuji Sugano, Toru Furuya and Takashi Ozawa
    Citation: BMC Nephrology 2019 20:196
    Content type: Research article Published on:

  7. Acute kidney injury (AKI) is a major complication of acute myocardial infarction(AMI), which can significantly increase mortality. This study is to analyze the related risk factors and establish a prediction s...

    Authors: Feng-bo Xu, Hong Cheng, Tong Yue, Nan Ye, He-jia Zhang and Yi-pu Chen
    Citation: BMC Nephrology 2019 20:195
    Content type: Research article Published on:

  8. Acid-base imbalance might promote the progression of chronic kidney disease (CKD), but whether nutrient-derived dietary acid load increases the risk of albuminuria or even high normoalbuminuria is unclear.

    Authors: Keiko Kabasawa, Michihiro Hosojima, Ribeka Takachi, Kazutoshi Nakamura, Yumi Ito, Akihiko Saito, Norie Sawada, Shoichiro Tsugane, Junta Tanaka and Ichiei Narita
    Citation: BMC Nephrology 2019 20:194
    Content type: Research article Published on:

  9. The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce.

    Authors: Consuelo Pedrós, Mónica Ávila, Ainhoa Gómez-Lumbreras, Marcela Manríquez and Rosa Morros
    Citation: BMC Nephrology 2019 20:193
    Content type: Study protocol Published on:

  10. Chronic kidney disease (CKD) is a worldwide public health problem. Clinical practice guidelines (CPGs) are being developed and implemented in order to improve clinical practice related to the detection and tre...

    Authors: Jorge Coronado Daza, Robin W. M. Vernooij, Karla Salas, Dimelza Osorio and Gerard Urrútia Cuchí
    Citation: BMC Nephrology 2019 20:192
    Content type: Research article Published on:

  11. Thrombophilia due to protein C (PC) and protein S (PS) deficiencies is highly prevalent among patients with stage 5 chronic kidney disease and is reported to arise due to extracorporeal circulation during hemo...

    Authors: Mayuri Ichinose, Naru Sasagawa, Tetsuo Chiba, Katsuhide Toyama, Yuzo Kayamori and Dongchon Kang
    Citation: BMC Nephrology 2019 20:191
    Content type: Research article Published on:

  12. Kidney transplant (KT) patients presenting with cardiovascular (CVD) events are being managed increasingly in non-transplant facilities. We aimed to identify drivers of mortality and costs, including transplan...

    Authors: Amit K. Mathur, Yu-Hui Chang, D. Eric Steidley, Raymond L. Heilman, Nabil Wasif, David Etzioni, Kunam S. Reddy and Adyr A. Moss
    Citation: BMC Nephrology 2019 20:190
    Content type: Research article Published on:

  13. To evaluate renal expression of C4d, a complement component in the classical/mannose binding lectin (MBL) pathway, in patients with primary Sjögren’s syndrome (pSS)-associated renal impairments.

    Authors: Wenli Xia, Bixia Gao, Lin Duan, Yan Li, Yubing Wen, Limeng Chen, Xuemei Li, Falei Zheng and Mingxi Li
    Citation: BMC Nephrology 2019 20:189
    Content type: Research article Published on:

  14. Patients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been proposed as a risk factor for mortality in end-stage C...

    Authors: Marta Cano-Megías, Pablo Guisado-Vasco, Hanane Bouarich, Gabriel de Arriba-de la Fuente, Patricia de Sequera-Ortiz, Concepción Álvarez-Sanz and Diego Rodríguez-Puyol
    Citation: BMC Nephrology 2019 20:188
    Content type: Research article Published on:

  15. Vitamin D deficiency is an important health concern because it is related to several comorbidities and mortality. However, its relationship with the risk of hematuria remains undetermined in the general popula...

    Authors: Hyunjin Ryu, Hyunjeong Cho, Yun Kyu Oh, Kwon Wook Joo, Yon Su Kim, Curie Ahn and Seung Seok Han
    Citation: BMC Nephrology 2019 20:187
    Content type: Research article Published on:

  16. The performance of urinary N-acetyl-β-D-glucosaminidase (uNAG) for the detection of acute kidney injury (AKI) was controversial. uNAG is positively correlated with blood glucose levels. Hyperglycemia is common...

    Authors: Lin Wang, Yujun Deng, Yiling Zhai, Feng Xu, Jinghua Li, Danqing Zhang, Lu Gao, Yating Hou, Xin OuYang, Linhui Hu, Jie Yuan, Heng Ye, Ruibin Chi and Chunbo Chen
    Citation: BMC Nephrology 2019 20:186
    Content type: Research article Published on:

  17. Angiopoietin-like-3 (Angptl3) knockout is known for its protective effects on podocyte injury and proteinuria in the early stage of adriamycin (ADR) nephropathy. The current study re-evaluated the renoprotecti...

    Authors: Rufeng Dai, Haimei Liu, Xinli Han, Junchao Liu, Yihui Zhai, Jia Rao, Qian Shen and Hong Xu
    Citation: BMC Nephrology 2019 20:185
    Content type: Research article Published on:

  18. Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study...

    Authors: Jia-Sian Hou, Yu-Li Lin, Chih-Hsien Wang, Yu-Hsien Lai, Chiu-Huang Kuo, Yi-Maun Subeq and Bang-Gee Hsu
    Citation: BMC Nephrology 2019 20:184
    Content type: Research article Published on:

  19. Accurate prediction of reference ranges of renal lengths facilitates clinical decision making. Currently a single renal-length-reference chart is used for both kidneys, which is solely based on the age of the ...

    Authors: W. D. Duminda, K. G. Pathirana, M. U. J. Fernando, R. A. N. K. K. Samarasinghe, W. D. H. A. Ananda, K. S. P. Silva, C. K. Dissanayake and P. K. B. Mahesh
    Citation: BMC Nephrology 2019 20:183
    Content type: Research article Published on:

  20. Acute kidney injury (AKI) is common after heart surgery. Neutrophil gelatinase-associated lipocalin (NGAL) is produced in injured kidney. NGAL has been used as an early plasma biomarker for AKI in patients und...

    Authors: Arie Passov, Liisa Petäjä, Marjut Pihlajoki, Ulla-Stina Salminen, Raili Suojaranta, Antti Vento, Sture Andersson, Ville Pettilä, Alexey Schramko and Eero Pesonen
    Citation: BMC Nephrology 2019 20:182
    Content type: Research article Published on:

  21. Glucose is a primary osmotic agent in peritoneal dialysis (PD) solutions, but its long-term use causes structural alteration of the peritoneal membrane (PM). Hyperbranched polyglycerol (HPG) is a promising alt...

    Authors: Bin Liu, Shijian Feng, Ghida Dairi, Qiunong Guan, Irina Chafeeva, Hao Wang, Richard Liggins, Gerald da Roza, Jayachandran N. Kizhakkedathu and Caigan Du
    Citation: BMC Nephrology 2019 20:181
    Content type: Research article Published on:

  22. Peritonitis is a common cause of catheter removal and mortality in the patient undergoing peritoneal dialysis (PD). Various pathogenic organisms have been identified as the etiology of PD-related peritonitis, ...

    Authors: Panai Song, Jun Deng, Tao Hou, Xiao Fu, Lei Zhang, Lin Sun and Yinghong Liu
    Citation: BMC Nephrology 2019 20:180
    Content type: Case report Published on:

  23. Reports on vitamin C in HD patients have shown effects of vitamin C deficiency in association with scurvy symptoms. Dialyzability of water soluble vitamins is high, and substantial losses in those who are dial...

    Authors: Jochen G. Raimann, Samer R. Abbas, Li Liu, Brett Larive, Gerald Beck, Peter Kotanko, Nathan W. Levin and Garry Handelman
    Citation: BMC Nephrology 2019 20:179
    Content type: Research article Published on:

  24. Adherence to phosphate binder treatment is important to prevent high serum phosphate level in chronic dialysis patients. We therefore wanted to investigate patient knowledge, beliefs about and adherence to pho...

    Authors: Bodil Jahren Hjemås, Katrine Bøvre, Liv Mathiesen, Jonas Christoffer Lindstrøm and Kathrin Bjerknes
    Citation: BMC Nephrology 2019 20:178
    Content type: Research article Published on:

  25. A classification tree model (CT-PIRP) was developed in 2013 to predict the annual renal function decline of patients with chronic kidney disease (CKD) participating in the PIRP (Progetto Insufficienza Renale P...

    Authors: Dino Gibertoni, Paola Rucci, Marcora Mandreoli, Mattia Corradini, Davide Martelli, Giorgia Russo, Elena Mancini and Antonio Santoro
    Citation: BMC Nephrology 2019 20:177
    Content type: Research article Published on:

  26. Inflammation is more common among African Americans (AAs), and it is associated with frailty, poor physical performance, and mortality in community-dwelling older adults. Given the elevated inflammation levels...

    Authors: Prakriti Shrestha, Christine E. Haugen, Nadia M. Chu, Ashton Shaffer, Jacqueline Garonzik-Wang, Silas P. Norman, Jeremy D. Walston, Dorry L. Segev and Mara A. McAdams-DeMarco
    Citation: BMC Nephrology 2019 20:176
    Content type: Research article Published on:

  27. The effect of a kidney transplant on a recipient extends beyond the restoration of kidney function. However, there is limited qualitative analysis of recipient perspectives on life following transplantation, p...

    Authors: Emily L. Tucker, Abigail R. Smith, Mark S. Daskin, Hannah Schapiro, Sabrina M. Cottrell, Evelyn S. Gendron, Peg Hill-Callahan, Alan B. Leichtman, Robert M. Merion, Stephen J. Gill and Kayse Lee Maass
    Citation: BMC Nephrology 2019 20:175
    Content type: Research article Published on:

  28. Increased morbidity and mortality are well documented in Status 7(inactive list) patients. Delays in transplantation secondary to prolonged periods on inactive status also negatively impacts transplant outcome...

    Authors: Ashish Kataria, Madan Gowda, Brian Paul Lamphron, Kabir Jalal, Rocco C. Venuto and Aijaz A. Gundroo
    Citation: BMC Nephrology 2019 20:174
    Content type: Technical advance Published on:

  29. Nephronophthisis (NPHP) is an autosomal recessive hereditary disease with highly variable clinical characteristics for which 20 genes (NPHP1–20) have been identified. NPHP1 is the major subtype leading to pediatr...

    Authors: Yiting Wang, Feng Chen, Jiali Wang, Yingwang Zhao and Fang Liu
    Citation: BMC Nephrology 2019 20:173
    Content type: Case report Published on:

  30. Reduced muscle strength and physical performance are prevalent in patients of maintenance hemodialysis (MHD), and deleterious changes in these parameters are associated with increased mortality.

    Authors: Yoshifumi Moriyama, Masahiko Hara, Sae Aratani, Hideaki Ishikawa, Kenichi Kono and Masatake Tamaki
    Citation: BMC Nephrology 2019 20:172
    Content type: Research article Published on:

  31. Steroidal mineralocorticoid receptor antagonists (MRAs) are recommended for the treatment of heart failure (HF) and resistant hypertension, both common comorbidities in patients with diabetes and chronic kidne...

    Authors: Michael Blankenburg, Anne-Kathrin Fett, Seline Eisenring, Gabriele Haas and Alain Gay
    Citation: BMC Nephrology 2019 20:171
    Content type: Research article Published on:

  32. Physicians are faced with a growing number of patients after renal transplantation undergoing graft-unrelated surgery. So far, little is known about the postoperative restitution of graft function and the risk...

    Authors: Ann-Kathrin Lederer, Dominic Haffa, Philipp Felgendreff, Frank Makowiec, Stefan Fichtner-Feigl, Roman Huber and Lampros Kousoulas
    Citation: BMC Nephrology 2019 20:170
    Content type: Research article Published on:

  33. The putative benefits of cinacalcet therapy for management of secondary hyperparathyroidism (SHPT) are thought to be most manifested when patients are taking it consistently and as prescribed. Real-world descr...

    Authors: Douglas S. Fuller, David Hallett, Paul J. Dluzniewski, Bruno Fouqueray, Michel Jadoul, Hal Morgenstern, Friedrich K. Port, Francesca Tentori and Ronald L. Pisoni
    Citation: BMC Nephrology 2019 20:169
    Content type: Research article Published on:

  34. Nephrogenic diabetes insipidus (DI) secondary to a urinary tract obstruction is a rare condition. Herein, we report a case of partial nephrogenic DI due to obstructive uropathy in a patient with Castleman’s di...

    Authors: Minah Kim, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim and Chang Seong Kim
    Citation: BMC Nephrology 2019 20:168
    Content type: Case report Published on:

  35. The influence of pre- or postprandial administration on pharmacokinetics of cyclosporine is supposed to be less in gel-based formulations than in microemulsions. This study was designed to investigate the infl...

    Authors: Anja Gäckler, Sebastian Dolff, Hana Rohn, Johannes Korth, Benjamin Wilde, Ute Eisenberger, Anna Mitchell, Andreas Kribben and Oliver Witzke
    Citation: BMC Nephrology 2019 20:167
    Content type: Research article Published on:

  36. Although the relationship between manifest chronic kidney disease and reduced cognitive function is well established, limited data exists on GFR and cognitive function in the general population. Both the brain...

    Authors: Silje Småbrekke, Henrik Schirmer, Toralf Melsom, Marit Dahl Solbu and Bjørn Odvar Eriksen
    Citation: BMC Nephrology 2019 20:166
    Content type: Research article Published on:

  38. There is increasing awareness that, besides patient survival, Quality of Life (QOL) is a relevant outcome factor for patients who have a chronic disease. In haemodialysis (HD) patients, intradialytic hypotensi...

    Authors: Johanna Kuipers, Jurjen K. Oosterhuis, Wolter Paans, Wim P. Krijnen, Carlo A. J. M. Gaillard, Ralf Westerhuis and Casper F. M. Franssen
    Citation: BMC Nephrology 2019 20:164
    Content type: Research article Published on:

  39. To describe the quality of life of adolescents initiating haemodialysis, to determine the factors associated with quality of life, and to assess coping strategies and their impact on quality of life.

    Authors: Stéphanie Clavé, Michel Tsimaratos, Mohamed Boucekine, Bruno Ranchin, Rémi Salomon, Olivier Dunand, Arnaud Garnier, Annie Lahoche, Marc Fila, Gwenaelle Roussey, Francoise Broux, Jérome Harambat, Sylvie Cloarec, Soraya Menouer, Georges Deschenes, Isabelle Vrillon…
    Citation: BMC Nephrology 2019 20:163
    Content type: Research article Published on:

  40. Antineutrophil cytoplasmic antibody associated vasculitis (AAV) is a group of diseases associated in most cases with the presence of anti-neutrophil cytoplasmic antibodies (ANCAs). Rituximab- based remission i...

    Authors: L. Caroti, C. L. Cirami, L. Di Maria, A. Larti, P. Carta, E. Dervishi, S. Farsetti, A. Tsalouchos, L. Novelli and E. E. Minetti
    Citation: BMC Nephrology 2019 20:162
    Content type: Research article Published on:

  41. Despite the good prognosis in patients with transplant organs, limited evidence is available on how immunosuppressants affect pregnancy. The aim of this study was to determine whether immunosuppressant use aff...

    Authors: Bo Hyon Yun, Dong Jin Joo, Seok Kyo Seo, Si Hyun Cho, Young Sik Choi and Byung Seok Lee
    Citation: BMC Nephrology 2019 20:161
    Content type: Research article Published on:

  42. Unintentional renal artery occlusion after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm remains one of the most unfavorable complications. Renal salvage options include percutaneous transl...

    Authors: Atsuko Uehara, Tomo Suzuki, Soichiro Hase, Hirofumi Sumi, Satoshi Hachisuka, Eisuke Fujimoto, Kouichirou Aida, Ryuto Nakazawa, Hideo Sasaki, Junki Koike, Tatsuya Chikaraishi, Yugo Shibagaki and Yuhji Marui
    Citation: BMC Nephrology 2019 20:160
    Content type: Case report Published on:

  43. To assess reasons for continuing practice variation in the management of childhood nephrotic syndrome despite expert reviews and guidelines, we are conducting a longitudinal cohort study in children with gluco...

    Authors: Susan M. Samuel, Allison Dart, Guido Filler, Martin Bitzan, Maury Pinsk, Cherry Mammen, Alberto Nettel-Aguirre, Maneka A. Perinpanayagam, Tomoko Takano, Rahul Chanchlani and Michael Zappitelli
    Citation: BMC Nephrology 2019 20:159
    Content type: Research article Published on:

  44. Pirfenidone is an orally active drug used for the treatment of idiopathic pulmonary fibrosis to slow loss of lung function; it acts mainly through an antifibrotic effect but also possesses antioxidant and anti...

    Authors: Ixchel Lima-Posada, Francesco Fontana, Rosalba Pérez-Villalva, Nathan Berman-Parks and Norma A. Bobadilla
    Citation: BMC Nephrology 2019 20:158
    Content type: Research article Published on:

  45. Haemolytic uraemic syndrome (HUS) is a thrombotic microangiopathy (TMA) characterized by predominant renal involvement. Several types of HUS can be distinguished: the most frequent « typical » HUS, due to shig...

    Authors: Stéphane Bally, Jacques Fourcade and Véronique Frémeaux-Bacchi
    Citation: BMC Nephrology 2019 20:157
    Content type: Case report Published on:

  46. As patients on daily hemodialysis (DHD) have heterogeneous profiles, DHD benefit in terms of survival is still debated. The aim of this study was to compare DHD practices in France and in Australia and New Zea...

    Authors: Adélaïde Pladys, Sahar Bayat, Cécile Couchoud, Cécile Vigneau and Stephen McDonald
    Citation: BMC Nephrology 2019 20:156
    Content type: Research article Published on:

  47. It has been reported that people living with HIV in West Africa exhibited the highest risks for chronic kidney disease (CKD) in the world. Here, we aimed at determining the CKD frequency and changes in kidney ...

    Authors: Nongodo Firmin Kaboré, Armel Poda, Jacques Zoungrana, Ollo Da, Laura Ciaffi, Aoua Semdé, Issouf Yaméogo, Adrien B. Sawadogo, Eric Delaporte, Nicolas Meda, Sophie Limou and Amandine Cournil
    Citation: BMC Nephrology 2019 20:155
    Content type: Research article Published on:

  48. Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insuffi...

    Authors: Alvin H. K. Karangizi, May Al-Shaghana, Sarah Logan, Sherwin Criseno, Rachel Webster, Kristien Boelaert, Peter Hewins and Lorraine Harper
    Citation: BMC Nephrology 2019 20:154
    Content type: Research article Published on:

  49. Dialysis patients are frequently exposed to Staphylococcus aureus due to stays in dialysis centers, hospitals or rest homes. The hemodialysis vascular access is a potential entry site for S. aureus, in particular...

    Authors: Matthias Scheuch, Sabrina Freiin von Rheinbaben, Antje Kabisch, Jonas Engeßer, Susanne Ahrendt, Thomas Dabers, Christian Kohler, Silva Holtfreter, Barbara M. Bröker and Sylvia Stracke
    Citation: BMC Nephrology 2019 20:153
    Content type: Research article Published on:

  50. In patients with end stage renal disease (ESRD), left ventricular (LV) hypertrophy with impaired LV function, which is called uremic cardiomyopathy (UC) is often observed. The UC historically has been consider...

    Authors: Tomasz Zapolski, Jacek Furmaga, Andrzej P. Wysokiński, Anna Wysocka, Sławomir Rudzki and Andrzej Jaroszyński
    Citation: BMC Nephrology 2019 20:152
    Content type: Research article Published on:
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BMC Nephrology

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