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  1. Content type: Research article

    The Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury (AKI) guidelines assign the same stage of AKI to patients whether they fulfil urine output criteria, serum creatinine criteria or both ...

    Authors: Samuel H. Howitt, Stuart W. Grant, Camila Caiado, Eric Carlson, Dowan Kwon, Ioannis Dimarakis, Ignacio Malagon and Charles McCollum

    Citation: BMC Nephrology 2018 19:149

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  2. Content type: Research article

    Chronic kidney disease (CKD) is highly prevalent but identification of patients at high risk for fast CKD progression before reaching end-stage renal disease in the short-term has been challenging. Whether fac...

    Authors: Alan S. Go, Jingrong Yang, Thida C. Tan, Claudia S. Cabrera, Bergur V. Stefansson, Peter J. Greasley and Juan D. Ordonez

    Citation: BMC Nephrology 2018 19:146

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  3. Content type: Case report

    Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate...

    Authors: Haruki Shida, Nobuhiro Hashimoto, Yoshihiro Kusunoki, Fumihiko Hattanda, Yayoi Ogawa, Terumasa Hayashi, Daigo Nakazawa, Sakiko Masuda, Utano Tomaru and Akihiro Ishizu

    Citation: BMC Nephrology 2018 19:145

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  4. Content type: Research article

    There are no guidelines for transitioning patients from chronic kidney disease stage 5 to hemodialysis. We conducted this study to determine if there are uniform patterns in how nephrologists transition patien...

    Authors: Mary C. Mallappallil, Steven Fishbane, Rimda Wanchoo, Edgar Lerma, Andrea Roche-Recinos and Moro Salifu

    Citation: BMC Nephrology 2018 19:147

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  5. Content type: Research article

    This study describes the time trend of renal replacement therapy for end-stage renal disease (ESRD) in the Provence-Alpes Côte d’Azur region (PACA) between 2004 and 2015, and forecasts up to 2030.

    Authors: Anne-Claire Durand, Elisabeth Jouve, Jean-Christophe Delarozière, Mohamed Boucekine, Ghizlane Izaaryene, Adeline Crémades, Franck Mazoué, Bénédicte Devictor, Asmatullah Kakar, Roland Sambuc, Philippe Brunet and Stéphanie Gentile

    Citation: BMC Nephrology 2018 19:141

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  6. Content type: Research article

    The mechanism of podocyte apoptosis is not fully understood. In addition, the role of the inositol 1,4,5-triphosphate receptor (IP3R)/glucose-regulated protein 75 (Grp75)/voltage-dependent anion channel 1 (VDAC1)...

    Authors: Han Xu, Na Guan, Ya-Li Ren, Qi-Jiao Wei, Ying-Hong Tao, Guo-Sheng Yang, Xiao-Ya Liu, Ding-Fang Bu, Ying Zhang and Sai-Nan Zhu

    Citation: BMC Nephrology 2018 19:140

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  7. Content type: Research article

    The patients with secondary hyperparathyroidism (SHPT) usually had reduced bone mineral density, which might lead to a substantial increase in osteoporosis, fracture and mortality. Although surgical interventi...

    Authors: Li Fang, Jining Wu, Jing Luo, Ping Wen, Mingxia Xiong, Jinlong Cao, Xiaolan Chen and Junwei Yang

    Citation: BMC Nephrology 2018 19:142

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  8. Content type: Case report

    Immunotactoid glomerulopathy (ITG) is a rare glomerulonephritis characterized by microtubular deposits. Immunofluorescence findings are necessary to differentiate ITG from other proliferative glomerular diseas...

    Authors: Shuma Hirashio, Takahiro Arima, Ayaka Satoh, Kouichi Mandai, Shigeo Hara and Takao Masaki

    Citation: BMC Nephrology 2018 19:143

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  9. Content type: Case report

    Arthrogryposis-Renal dysfunction-Cholestasis syndrome (ARC, MIM#208085) is a rare multisystem disease due to mutations in the VPS33B and VIPAR genes, both involved in maintaining apical-basolateral cell polarity....

    Authors: Alejandra Rosales, Maissa Mhibik, Paul Gissen, Oscar Segarra, Susana Redecillas and Gema Ariceta

    Citation: BMC Nephrology 2018 19:144

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  10. Content type: Case report

    Renal replacement therapy (RRT) with regional citrate anticoagulation (RCA) is an important therapeutic approach for refractory hypercalcemia complicated with renal failure. However, RCA has the potential to i...

    Authors: Buyun Wu, Jing Wang, Guang Yang, Changying Xing and Huijuan Mao

    Citation: BMC Nephrology 2018 19:136

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  11. Content type: Research article

    Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that meas...

    Authors: Meaghan Lunney, Bronwyn Tonelli, Rachel Lewis, Natasha Wiebe, Chandra Thomas, Jennifer MacRae and Marcello Tonelli

    Citation: BMC Nephrology 2018 19:137

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  12. Content type: Research article

    Severe infections are common complications of immunosuppressive treatment for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with renal involvement. We investigated the clinical charact...

    Authors: Liu Yang, Honglang Xie, Zhengzhao Liu, Yinghua Chen, Jinquan Wang, Haitao Zhang, Yongchun Ge and Weixin Hu

    Citation: BMC Nephrology 2018 19:138

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  13. Content type: Research article

    Chronic kidney disease (CKD) is global health concern and priority. It is the 12th leading cause of death worldwide. Protein Energy Wasting occurs in 20–25% of patients with chronic kidney disease and can lead...

    Authors: Lydia Namuyimbwa, Collins Atuheire, Joel Okullo and Robert Kalyesubula

    Citation: BMC Nephrology 2018 19:139

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  14. Content type: Research article

    A combination of safety concerns and labeling changes impacted use of erythropoiesis-stimulating agents (ESAs) in renal anemia. Data regarding contemporary utilization in pre-dialysis chronic kidney disease (C...

    Authors: Heide A. Stirnadel-Farrant, Jiacong Luo, Lata Kler, Borut Cizman, Delyth Jones, Steven M. Brunelli and Alexander R. Cobitz

    Citation: BMC Nephrology 2018 19:135

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  15. Content type: Research article

    The high mortality and cardiovascular disease (CVD) burden in patients with end-stage renal disease (ESRD) is well-documented. Recent literature suggests that acute kidney injury is also associated with CVD. I...

    Authors: Benjamin J. Lee, Chi-yuan Hsu, Rishi V. Parikh, Thomas K. Leong, Thida C. Tan, Sophia Walia, Kathleen D. Liu, Raymond K. Hsu and Alan S. Go

    Citation: BMC Nephrology 2018 19:134

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  16. Content type: Research article

    Efforts are underway to improve living kidney donor (LKD) education, but current LKD concerns and information-gathering preferences have not been ascertained to inform evidence-based resource development. As a...

    Authors: Jessica M. Ruck, Sarah E. Van Pilsum Rasmussen, Macey L. Henderson, Allan B. Massie and Dorry L. Segev

    Citation: BMC Nephrology 2018 19:130

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  17. Content type: Case report

    Morbidity associated with monoclonal gammopathy of renal significance is high due to the severe renal lesions and the associated systemic alterations. Accordingly, early diagnosis is fundamental, as is stoppin...

    Authors: Juana Alonso-Titos, Lara Perea-Ortega, Eugenia Sola, Alvaro Torres-Rueda, Myriam León, Remedios Toledo, Ana D. Duarte, Teresa Vazquez, Maria Dolores Martinez-Esteban, Alicia Bailen, Pedro Ruiz-Esteban and Domingo Hernandez

    Citation: BMC Nephrology 2018 19:129

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  18. Content type: Case report

    Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%.

    Authors: Alexandre Le Joncour, Laurent Mesnard, Alexandre Hertig and Thomas Robert

    Citation: BMC Nephrology 2018 19:133

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  19. Content type: Case report

    Catastrophic antiphospholipid syndrome (CAPS) is a rare, life-threatening form of antiphospholipid syndrome (APS) involving many organs and leading to their insufficiency. The pathogenesis of CAPS is associate...

    Authors: Aleksandra Rymarz and Stanisław Niemczyk

    Citation: BMC Nephrology 2018 19:132

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  20. Content type: Research article

    Female sex has been included as a risk factor in models developed to predict the risk of acute kidney injury (AKI) associated with cardiac surgery, aminoglycoside nephrotoxicity and contrast-induced nephropath...

    Authors: Joel Neugarten, Ladan Golestaneh and Nitin V. Kolhe

    Citation: BMC Nephrology 2018 19:131

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  21. Content type: Research article

    The 2014 Consensus Conference on Best Practices in Living Kidney Donations recognized live donor kidney transplantation as the best treatment for late-stage kidney disease, yielding superior graft and patient ...

    Authors: Walter G. Wasser, Geoffrey Boner, Meni Koslowsky and Adi Lazar

    Citation: BMC Nephrology 2018 19:128

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  22. Content type: Research article

    Diabetic nephropathy requires periodic monitoring, dietary modification, and early intervention to prevent the disease severity within limited resource settings. To emphasize the importance of continuous care ...

    Authors: Yun Jung Jang, Yoon Soo Choy, Chung Mo Nam, Ki Tae Moon and Eun-Cheol Park

    Citation: BMC Nephrology 2018 19:127

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  23. Content type: Research article

    Accurate contemporary data on the burden of Chronic Kidney Disease (CKD) on the African continent are lacking. We determined the prevalence of CKD in adult populations living in Africa, and variations by stage...

    Authors: Arnaud D. Kaze, Titilayo Ilori, Bernard G. Jaar and Justin B. Echouffo-Tcheugui

    Citation: BMC Nephrology 2018 19:125

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  24. Content type: Research article

    Patient activation is associated with better outcomes and lower costs. Although the concept is widely investigated, little attention was given to patient activation and its predictors in patients undergoing he...

    Authors: Liesbet Van Bulck, Kathleen Claes, Katrien Dierickx, Annelies Hellemans, Sofie Jamar, Sven Smets and Gijs Van Pottelbergh

    Citation: BMC Nephrology 2018 19:126

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  25. Content type: Research article

    People with chronic renal disease are insulin resistant. We hypothesized that in a healthy population, baseline renal function is associated with insulin sensitivity three years later.

    Authors: Soline Siméon, Ziad Massy, Kurt Højlund, Katarina Lalic, Francesca Porcellati, Jacqueline Dekker, John Petrie, Gemma Currie and Beverley Balkau

    Citation: BMC Nephrology 2018 19:124

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  26. Content type: Case report

    Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and d...

    Authors: Jan Tuma, Holger Moch, Gerd Stuckmann, Walter Gysel and Andreas L. Serra

    Citation: BMC Nephrology 2018 19:123

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  27. Content type: Research article

    Both peritoneal small solute transport and peritoneal protein clearance are closely linked to outcomes in peritoneal dialysis (PD) patients. However, the associated factors of these two components are not full...

    Authors: Yuanyuan Shi, Hao Yan, Jiangzi Yuan, He Zhang, Jiaying Huang, Zhaohui Ni, Jiaqi Qian and Wei Fang

    Citation: BMC Nephrology 2018 19:119

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  28. Content type: Research article

    Inadequate volume control may be a main contributor to poor survival and high mortality in hemodialysis patients. Bioimpedance measurement has the potential to improve fluid management, but several dialysis ce...

    Authors: Jenny Stenberg, Catrin Henriksson, Magnus Lindberg and Hans Furuland

    Citation: BMC Nephrology 2018 19:121

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  29. Content type: Case report

    Podocyte phospholipase A2 receptor (PLA2R) is a major target antigen in idiopathic adult membranous nephropathy (MN). Histological PLA2R staining in the renal tissue has proven to be useful for the detection of i...

    Authors: Kenta Tominaga, Takahiro Uchida, Toshihiko Imakiire, Kenji Itoh, Hideyuki Shimazaki, Kuniaki Nakanishi, Hiroo Kumagai and Naoki Oshima

    Citation: BMC Nephrology 2018 19:120

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  31. Content type: Case report

    Liddle’s syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome prese...

    Authors: Eriko Yamaguchi, Kazuhiro Yoshikawa, Izaya Nakaya, Karen Kato, Yoshikazu Miyasato, Terumasa Nakagawa, Yutaka Kakizoe, Masashi Mukoyama and Jun Soma

    Citation: BMC Nephrology 2018 19:122

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  32. Content type: Research article

    There are limited data on the associations of circulating angiogenic factors with chronic kidney disease (CKD). We investigate the associations of circulating vascular endothelial growth factor (VEGF)-A, angio...

    Authors: Christopher E. Anderson, L. Lee Hamm, Gem Batuman, Damodar R. Kumbala, Chung-Shiuan Chen, Swapna G. Kallu, Ravi Siriki, Shilpa Gadde, Myra A. Kleinpeter, N. Kevin Krane, Eric E. Simon, Jiang He and Jing Chen

    Citation: BMC Nephrology 2018 19:117

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  33. Content type: Research article

    The magnitude effects of human leukocyte antigen (HLA) mismatching on post-transplant outcomes of kidney transplantation remain controversial. We aim to quantitatively assess the associations of HLA mismatchin...

    Authors: Xinmiao Shi, Jicheng Lv, Wenke Han, Xuhui Zhong, Xinfang Xie, Baige Su and Jie Ding

    Citation: BMC Nephrology 2018 19:116

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  34. Content type: Research article

    About 40–50% of patients with familial microscopic hematuria (FMH) caused by thin basement membrane nephropathy (TBMN) inherit heterozygous mutations in collagen IV genes (COL4A3, COL4A4). On long follow-up, the ...

    Authors: Konstantinos Voskarides, Gregory Papagregoriou, Despina Hadjipanagi, Ioanelli Petrou, Isavella Savva, Avraam Elia, Yiannis Athanasiou, Androulla Pastelli, Maria Kkolou, Michalis Hadjigavriel, Christoforos Stavrou, Alkis Pierides and Constantinos Deltas

    Citation: BMC Nephrology 2018 19:114

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  35. Content type: Research article

    Chronic kidney disease of unknown origin (CKDu) in Sri Lanka is grouped with several other epidemics of similar nature across the world as Chronic Interstitial Nephritis in Agricultural Communities (CINAC). In...

    Authors: S. B. Agampodi, G. S. Amarasinghe, P. G. C. R. Naotunna, C. S. Jayasumana and S. H. Siribaddana

    Citation: BMC Nephrology 2018 19:115

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  36. Content type: Research article

    The calcimimetic agent cinacalcet is effective for the management of secondary hyperparathyroidism (SHPT) in dialysis patients. Changes to reimbursement of cinacalcet in Australia provided an opportunity to as...

    Authors: Irene Ruderman, Edward R. Smith, Nigel D. Toussaint, Tim D. Hewitson and Stephen G. Holt

    Citation: BMC Nephrology 2018 19:113

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  37. Content type: Case report

    Although the relationship between hyperparathyroidism and hypertension has been described for decades, the role of hyperparathyroidism in hypertension in dialysis is still unclear. Following the case of a seve...

    Authors: Andreea Corina Sofronie, Isabelle Kooij, Claude Bursot, Giulia Santagati, Jean-Philippe Coindre and Giorgina Barbara Piccoli

    Citation: BMC Nephrology 2018 19:112

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  38. Content type: Case report

    Lipodystrophy syndromes are rare disorders of variable body fat loss associated with potentially serious metabolic complications. Familial partial lipodystrophy (FPLD) is mostly inherited as an autosomal domin...

    Authors: Ru-Xuan Chen, Lei Zhang, Wei Ye, Yu-Bing Wen, Nuo Si, Hang Li, Ming-Xi Li, Xue-Mei Li and Ke Zheng

    Citation: BMC Nephrology 2018 19:111

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  39. Content type: Research article

    The impact of the low-protein diet on nutrition in CKD diabetics is uncertain.

    Authors: Vincenzo Bellizzi, Patrizia Calella, Julia Nava Hernández, Verónica Figueroa González, Silvia Moran Lira, Serena Torraca, Rocio Urbina Arronte, Pietro Cirillo, Roberto Minutolo and Rafael A. Montúfar Cárdenas

    Citation: BMC Nephrology 2018 19:110

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  40. Content type: Research article

    This study aimed to evaluate the longitudinal changes in cardiac structure and function in incident-automated peritoneal dialysis (APD) patients.

    Authors: Jin-Bor Chen, Ben-Chung Cheng, Wen-Hao Liu, Shang-Chih Liao, Mao-Young Morgan Fu, Sin-Hua Moi and Cheng-Hong Yang

    Citation: BMC Nephrology 2018 19:109

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  41. Content type: Research article

    African Americans have persistently poor access to living donor kidney transplants (LDKT). We conducted a small randomized trial to provide preliminary evidence of the effect of informational decision support ...

    Authors: L. Ebony Boulware, Patti L. Ephraim, Jessica Ameling, LaPricia Lewis-Boyer, Hamid Rabb, Raquel C. Greer, Deidra C. Crews, Bernard G. Jaar, Priscilla Auguste, Tanjala S. Purnell, Julio A. Lamprea-Monteleagre, Tope Olufade, Luis Gimenez, Courtney Cook, Tiffany Campbell, Ashley Woodall…

    Citation: BMC Nephrology 2018 19:107

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  42. Content type: Case report

    Urinothorax is defined as the presence of urine in the pleural space and is a rather rare cause of transudate pleural effusion. The potential etiologies are urinary tract obstruction and trauma. Diagnosis requ...

    Authors: Tae Won Lee, Ha Nee Jang, Hyun Seop Cho, See Min Choi, Bong-Hoi Choi, Eunjin Bae, Se-Ho Chang and Dong Jun Park

    Citation: BMC Nephrology 2018 19:104

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  43. Content type: Case report

    Complement component 3 (C3) glomerulopathy, which includes dense deposit disease (DDD) and C3 glomerulonephritis, is caused by dysregulation of the alternative complement pathway. In most cases, C3 glomerulopa...

    Authors: Shuma Hirashio, Ayaka Satoh, Takahiro Arima, Kouichi Mandai, Tadasuke Awaya, Kumi Oshima, Shigeo Hara and Takao Masaki

    Citation: BMC Nephrology 2018 19:108

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  44. Content type: Study protocol

    Calcineurin inhibitor induced nephrotoxicity contributes to late allograft failure in kidney transplant patients. Evidence points towards aldosterone to play a role in the development of fibrosis in multiple o...

    Authors: Line Aas Mortensen, Helle C. Thiesson, Birgitte Tougaard, Martin Egfjord, Anne Sophie Lind Fischer and Claus Bistrup

    Citation: BMC Nephrology 2018 19:105

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  45. Content type: Case report

    Monoclonal gammopathy causes several kinds of renal pathology. A rare and special form is monoclonal gammopathy-induced C3 glomerulopathy (MG-C3G). Like idiopathic C3G, MG-C3G frequently leads to end-stage ren...

    Authors: Philipp Moog, Philipp J. Jost and Maike Büttner-Herold

    Citation: BMC Nephrology 2018 19:106

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  46. Content type: Research article

    Acute kidney injury (AKI) is a common post-cardiac surgery complication and influences patient morbidity and prognosis. This study was designed to identify preoperative candidate urine biomarkers in patients u...

    Authors: Michael L. Merchant, Michael E. Brier, Mark S. Slaughter, Jon B. Klein and Kenneth R. McLeish

    Citation: BMC Nephrology 2018 19:102

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  47. Content type: Research article

    We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients. We examined wh...

    Authors: Shinshu Katayama, Kansuke Koyama, Yuya Goto, Toshitaka Koinuma, Ken Tonai, Jun Shima, Masahiko Wada and Shin Nunomiya

    Citation: BMC Nephrology 2018 19:101

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  48. Content type: Research article

    Kidney impairment constitutes severe risk for cardiovascular disease, stroke and all-cause mortality, and early identification and prevention of kidney impairment is critical to effective management of prognos...

    Authors: Shihui Fu, Yi Guo, Leiming Luo and Ping Ye

    Citation: BMC Nephrology 2018 19:103

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  49. Content type: Research article

    Health-Related Quality of Life (HRQoL) assessment after kidney transplantation has become an important tool in evaluating outcomes. This study aims to identify the associated factors with HRQoL among a represe...

    Authors: Yosra Mouelhi, Elisabeth Jouve, Marine Alessandrini, Nathalie Pedinielli, Valérie Moal, Aurélie Meurette, Elisabeth Cassuto, Georges Mourad, Antoine Durrbach, Bertrand Dussol and Stéphanie Gentile

    Citation: BMC Nephrology 2018 19:99

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  50. Content type: Research article

    The transition from pre-dialysis chronic kidney disease (CKD) to renal replacement therapy (RRT) is a stressful event. Anxiety, depression and stress are frequent conditions in this population, and might play ...

    Authors: Cicero Italo L. Bezerra, Bruno C. Silva and Rosilene M. Elias

    Citation: BMC Nephrology 2018 19:98

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