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  1. Sepsis is a common syndrome in critically ill patients and easily leads to the occurrence of acute kidney injury (AKI), with high mortality rates. This study aimed to investigate the diagnostic value of urine ...

    Authors: Longxiang Su, Lin Feng, Changting Liu, Zhaoxu Jiang, Ming Li, Kun Xiao, Peng Yan, Yanhong Jia, Dan Feng and Lixin Xie
    Citation: BMC Nephrology 2012 13:123
  2. In kidney transplant (Kt) recipients , hypertension is a major risk for cardiovascular complications but also for graft failure. Blood pressure (BP) control is therefore mandatory. Office BP (OBP) remains freq...

    Authors: Annie Saint-Remy, Mélanie Somja, Karen Gellner, Laurent Weekers, Catherine Bonvoisin and Jean-Marie Krzesinski
    Citation: BMC Nephrology 2012 13:121
  3. Bioimpedance analysis (BIA) has been reported as helpful in identifying hypervolemia. Observation data showed that hypervolemic maintenance hemodialysis (MHD) patients identified using BIA methods have higher ...

    Authors: Li Liu, Gang Long, Jianwei Ren, Jijun Li, Jinsheng Xu, Jinghong Lei, Mao Li, Moyan Qiu, Ping Yuan, Weiming Sun, Shan Lin, Wenjun Liu, Yi Sun, Yingchun Ma, Yonghui Mao, Yulan Shen…
    Citation: BMC Nephrology 2012 13:120
  4. Uremic pruritus (UP) is a significant complication in ESRD patients and substantially impairs their quality of life. UP is considered to be a skin manifestation of chronic inflammation. Because sericin can sup...

    Authors: Pornanong Aramwit, Orathai Keongamaroon, Tippawan Siritientong, Nipaporn Bang and Ouppatham Supasyndh
    Citation: BMC Nephrology 2012 13:119
  5. The kidney is a major target organ for systemic amyloidosis that often affects the kidney including proteinura, and elevated serum creatinine (Cr). The correlation between amount of amyloid deposits and clinic...

    Authors: Takeshi Kuroda, Naohito Tanabe, Daisuke Kobayashi, Yoko Wada, Shuichi Murakami, Masaaki Nakano and Ichiei Narita
    Citation: BMC Nephrology 2012 13:118
  6. Urolithiasis is one of the most common conditions seen in emergency departments (ED) worldwide, with an increasing frequency in geriatric patients (>65 years). Given the high costs of emergency medical urolith...

    Authors: Spyridon Arampatzis, Gregor Lindner, Filiz Irmak, Georg-Christian Funk, Heinz Zimmermann and Aristomenis K Exadaktylos
    Citation: BMC Nephrology 2012 13:117
  7. Mineral and bone disorder (MBD) in patients with chronic kidney disease is associated with increased morbidity and mortality. Studies regarding the status of MBD treatment in developing countries, especially i...

    Authors: Xianglei Kong, Luxia Zhang, Ling Zhang, Nan Chen, Yong Gu, Xueqing Yu, Wenhu Liu, Jianghua Chen, Liren Peng, Weijie Yuan, Hua Wu, Wei Chen, Minhua Fan, Liqun He, Feng Ding, Xiangmei Chen…
    Citation: BMC Nephrology 2012 13:116
  8. In common with Indigenous populations elsewhere, Indigenous Australians have higher incidence of end-stage kidney disease (ESKD), but lower transplantation rates than their non-Indigenous counterparts. Underst...

    Authors: Kate Anderson, Joan Cunningham, Jeannie Devitt, Cilla Preece and Alan Cass
    Citation: BMC Nephrology 2012 13:114
  9. The inevitable post-inflammatory fibrosis and adhesion often compromises future treatment in peritoneal dialysis patients. Here, we describe a patient who experienced an unusual form of peritoneal adhesion tha...

    Authors: Jiun-Chi Huang, Szu-Chia Chen, Tsung-Kun Yang, Fang-Jung Yu, Fu Ou-Yang and Jer-Ming Chang
    Citation: BMC Nephrology 2012 13:113
  10. Medical, ethical and financial dilemmas may arise in treating undocumented-uninsured patients with end-stage renal disease (ESRD). Hereby we describe the 10-year experience of treating undocumented-uninsured E...

    Authors: Gil Chernin, Amir Gal-Oz, Idit F Schwartz, Moshe Shashar, Doron Schwartz and Talia Weinstein
    Citation: BMC Nephrology 2012 13:112
  11. Administration of HMG-CoA reductase inhibitors (statins), prior to ischemia or prior to reperfusion has been shown to decrease ischemia-reperfusion renal injury in animal studies. It is unknown whether this pr...

    Authors: Janske Reiling, David W Johnson, Peter S Kruger, Peter Pillans and Daryl R Wall
    Citation: BMC Nephrology 2012 13:111
  12. The clinical outcomes of ST-segment elevation myocardial infarction (STEMI) are poor in patients with renal insufficiency. This study investigated changes in the likelihood that patients received optimal medic...

    Authors: Joon Seok Choi, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Myung Ho Jeong, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim and Soo Wan Kim
    Citation: BMC Nephrology 2012 13:110
  13. Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease pr...

    Authors: Bin Liu, Chenghai Li, Zijuan Liu, Zonghan Dai and Yunxia Tao
    Citation: BMC Nephrology 2012 13:109
  14. Many patients with advanced chronic kidney disease are referred late to renal units. This is associated with negative aspects. The purpose of the present study was to characterize late versus early referrals f...

    Authors: Kristine Hommel, Mette Madsen and Anne-Lise Kamper
    Citation: BMC Nephrology 2012 13:108
  15. Patients with nephrotic syndrome are at an increased risk of thromboembolic events (TEs). However, this association has not been thoroughly investigated in adult patients with idiopathic membranous nephropathy...

    Authors: Sanjeev Kumar, Ananda Chapagain, Dorothea Nitsch and Muhammad M Yaqoob
    Citation: BMC Nephrology 2012 13:107
  16. Hemodiafiltration (HDF), as a convective blood purification technique, has been associated with favorable outcomes improved phosphate control, removal of middle-molecules such as Beta2-microglobulin and the oc...

    Authors: Franklin G Mora-Bravo, Guadalupe De-La-Cruz, Sonia Rivera, Alfonso Mariscal Ramírez, Jochen G Raimann and Héctor Pérez-Grovas
    Citation: BMC Nephrology 2012 13:106
  17. Bone marrow (BM) stem cells have been reported to contribute to tissue repair after kidney injury model. However, there is no direct evidence so far that BM cells can trans-differentiate into renal stem cells.

    Authors: Xiaohua Jia, Xiaoqiang Xie, Guowei Feng, He Lű, Qinjun Zhao, Yongzhe Che, Yizhou Zheng, Zhongchao Han, Yong Xu, Zongjin Li and Deling Kong
    Citation: BMC Nephrology 2012 13:105
  18. The relationship between glycemic control and lipid abnormalities with urinary albumin-creatinine ratio (ACR) in chronic kidney disease (CKD) patients with diabetes mellitus (DM) is unknown. We sought to inves...

    Authors: Subhasish Bose, Andrew S Bomback, Nehal N Mehta, Shu-Cheng Chen, Suying Li, Adam Whaley-Connell, Joseph Benjamin and Peter A McCullough
    Citation: BMC Nephrology 2012 13:104
  19. Limited data exist on the impact of living kidney donation on the donor-recipient relationship. Purpose of this study was to explore motivations to donate or accept a (living donor) kidney, whether expected re...

    Authors: Ingrid B de Groot, Karen Schipper, Sandra van Dijk, Paul J M van der Boog, Anne M Stiggelbout, Andrzej G Baranski and Perla J Marang-van de Mheen
    Citation: BMC Nephrology 2012 13:103
  20. The vitamin D receptor activator paricalcitol has been shown to reduce albuminuria. Whether this is a unique property of paricalcitol, or common to all vitamin D analogues, is unknown. The primary aim of this ...

    Authors: Hanne Skou Jørgensen, Simon Winther, Johan Vestergaard Povlsen and Per Ivarsen
    Citation: BMC Nephrology 2012 13:102
  21. This retrospective study was undertaken to determine the incidence of kidney dysfunction (KD) and to identify potential risk factors contributing to development of KD in orthopaedic population following an ele...

    Authors: Konstantinos Kateros, Christos Doulgerakis, Spyridon P Galanakos, Vasileios I Sakellariou, Stamatios A Papadakis and George A Macheras
    Citation: BMC Nephrology 2012 13:101
  22. Peripheral artery disease (PAD) is a condition characterized by restricted blood flow to the extremities, and is especially common in the elderly. PAD increases the risk for mortality and morbidity in patients...

    Authors: Chun-Chuan Lee, Chih-Jen Wu, Li-Hua Chou, Su-Mei Shen, Sheng-Fang Chiang, Pi-Chu Jen, Mei-Ching Yeh and Chi-Feng Pan
    Citation: BMC Nephrology 2012 13:100
  23. Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/repe...

    Authors: Michael Osthoff, Vanja Piezzi, Theresia Klima, Andreas Christ, Ivana Marana, Sabine Hartwiger, Tobias Breidthardt, Giancarlo Marenzi, Marten Trendelenburg and Christian Mueller
    Citation: BMC Nephrology 2012 13:99
  24. Coronary collateral circulation plays an important role to protect myocardium from ischemia, preserve myocardial contractility and reduce cardiovascular events. Chronic kidney disease (CKD) is associated with ...

    Authors: Po-Chao Hsu, Suh-Hang Juo, Ho-Ming Su, Szu-Chia Chen, Wei-chung Tsai, Wen-Ter Lai, Sheng-Hsiung Sheu and Tsung-Hsien Lin
    Citation: BMC Nephrology 2012 13:98
  25. The status of immunocompromised patients is well recognized in end stage renal disease (ESRD). As described recently, this acquired immune dysfunction in the uremic milieu may be one of the main pathogenic fac...

    Authors: Shih-Yi Lin, Jiung-Hsiun Liu, Shu-Ming Wang, I-Kuan Wang, Chen-An Tsai, Yao-lung Liu, Hsin-Hung Lin, Chiz-Chung Chang and Chiu-Ching Huang
    Citation: BMC Nephrology 2012 13:97
  26. Because of the rapid growth in elderly population, polypharmacy has become a serious public health issue worldwide. Although acute renal failure (ARF) is one negative consequence of polypharmacy, the associati...

    Authors: Yi-Ping Chang, San-Kuei Huang, Ping Tao and Ching-Wen Chien
    Citation: BMC Nephrology 2012 13:96
  27. Peginesatide is a peptide-based erythropoiesis-stimulating agent that was designed and engineered to stimulate specifically the erythropoietin receptor dimer that governs erythropoiesis. The primary objective ...

    Authors: Anatole Besarab, Steven N Zeig, Edouard R Martin, Pablo E Pergola, Frederick C Whittier, Raja I Zabaneh, Brigitte Schiller, Martha Mayo, Carol A Francisco, Krishna R Polu and Anne-Marie Duliege
    Citation: BMC Nephrology 2012 13:95
  28. Cardiovascular disease (CVD) is the main cause of death in patients on chronic dialysis. The question whether dialysis modality impacts cardiovascular risk remains to be addressed. China Collaborative Study on...

    Authors: Fanfan Hou, Jianping Jiang, Jianghua Chen, Xueqing Yu, Qiugen Zhou, Pingyan Chen, Changlin Mei, Fei Xiong, Wei Shi, Wei Zhou, Xusheng Liu, Shiren Sun, Di Xie, Jun Liu, Ping Zhang, Xiao Yang…
    Citation: BMC Nephrology 2012 13:94
  29. Renal failure is one of the most serious complications associated with autosomal dominant polycystic kidney disease (ADPKD). To date, early markers have failed to predict renal function deterioration at the ea...

    Authors: Hayne Cho Park, Jin Ho Hwang, Ah-Young Kang, Han Ro, Myung-Gyu Kim, Jung Nam An, Ji In Park, Seung Hyup Kim, Jaeseok Yang, Yun Kyu Oh, Kook-Hwan Oh, Jung Woo Noh, Hae Il Cheong, Young-Hwan Hwang and Curie Ahn
    Citation: BMC Nephrology 2012 13:93
  30. Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin ...

    Authors: Bunyong Phakdeekitcharoen and Kochawan Boonyawat
    Citation: BMC Nephrology 2012 13:92
  31. Polycystic Kidney Disease (PKD) is a genetic condition in which dedifferentiated and highly proliferative epithelial cells form renal cysts and is frequently treated by renal transplantation. Studies have repo...

    Authors: Elizabeth Verghese, Chad Johnson, John F Bertram, Sharon D Ricardo and James A Deane
    Citation: BMC Nephrology 2012 13:91
  32. Chronic kidney disease is an important public health threat. Such patients present high morbidity and mortality due to cardiovascular disease, with low quality of life and survival, and also high expenditure r...

    Authors: Franklin C Barcellos, Iná S Santos, Grégore Iven Mielke, Fabrício B del Vecchio and Pedro C Hallal
    Citation: BMC Nephrology 2012 13:90
  33. The renin-angiotensin-aldosterone system (RAAS) plays an important role in the progression of chronic kidney disease (CKD). Although dual RAAS inhibition results in worse renal outcomes than monotherapy in hig...

    Authors: Szu-yuan Li, Yung-Tai Chen, Wu-Chang Yang, Der-Cherng Tarng, Chih-Ching Lin, Chih-Yu Yang and Wen-Sheng Liu
    Citation: BMC Nephrology 2012 13:89
  34. Although several studies have demonstrated early survival advantages with peritoneal dialysis (PD) over hemodialysis (HD), the reason for the excess mortality observed among incident HD patients remains to be ...

    Authors: Luis Coentrão, Carla Santos-Araújo, Claudia Dias, Ricardo Neto and Manuel Pestana
    Citation: BMC Nephrology 2012 13:88
  35. Kidney disease is associated with an increased total mortality and cardiovascular morbimortality in the general population and in patients with Type 2 diabetes. The aim of this study is to determine the preval...

    Authors: Gabriel Coll-de-Tuero, Manel Mata-Cases, Antonio Rodriguez-Poncelas, Josep MA Pepió, Pilar Roura, Belen Benito, Josep Franch-Nadal and Marc Saez
    Citation: BMC Nephrology 2012 13:87
  36. One hallmark of uremia is the impairment of neuro-cognitive function. Anecdotal clinical description from the early days of chronic dialysis therapy impressively illustrates the improvement of those functions ...

    Authors: Sabrina Schneider, Anne-Kathrin Malecki, Olaf Boenisch, Robby Schönfeld and Jan T Kielstein
    Citation: BMC Nephrology 2012 13:86
  37. Chronic kidney disease is common in HIV positive patients and renal tubular dysfunction has been reported in those receiving combination antiretroviral therapy (cART). Tenofovir (TFV) in particular has been li...

    Authors: Lucy J Campbell, Tracy Dew, Rashim Salota, Emily Cheserem, Lisa Hamzah, Fowzia Ibrahim, Pantelis A Sarafidis, Caje F Moniz, Bruce M Hendry, Mary Poulton, Roy A Sherwood and Frank A Post
    Citation: BMC Nephrology 2012 13:85
  38. IgA nephropathy has been reported as a renal involvement in Crohn’s disease. Crescentic IgA nephropathy, which accounts for fewer than 5% of cases of IgA nephropathy, has a poorer prognosis than other forms of...

    Authors: Ji-Young Choi, Chung Hoon Yu, Hee-Yeon Jung, Min Kyu Jung, Yong-Jin Kim, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim and Sun-Hee Park
    Citation: BMC Nephrology 2012 13:84
  39. Sickle cell disease (SCD) leads to tissue hypoxia resulting in chronic organ dysfunction including SCD associated nephropathy. The goal of our study was to determine the best equation to estimate glomerular fi...

    Authors: Jean-Benoît Arlet, Jean-Antoine Ribeil, Gilles Chatellier, Dominique Eladari, Sophie De Seigneux, Jean-Claude Souberbielle, Gérard Friedlander, Marianne de Montalembert, Jacques Pouchot, Dominique Prié and Marie Courbebaisse
    Citation: BMC Nephrology 2012 13:83
  40. Transparency in quality of care (QoC) is stimulated and hospitals are compared and judged on the basis of indicators of performance on specific treatment targets. In patients with chronic kidney disease, QoC d...

    Authors: Mieke J Peeters, Arjan D van Zuilen, Jan AJG van den Brand, Peter J Blankestijn, Marc AGJ ten Dam and Jack FM Wetzels
    Citation: BMC Nephrology 2012 13:82
  41. Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chron...

    Authors: Sophia Ross, Kerstin Benz, Katja Sauerstein, Kerstin Amann, Jörg Dötsch and Katalin Dittrich
    Citation: BMC Nephrology 2012 13:81
  42. The pathogenesis of pulmonary hypertension (PH) in hemodialysis is still unclear. The aim of this study was to identify the risk factors associated with the presence of PH in chronic hemodialysis patients and ...

    Authors: Hugo Hyung Bok Yoo, Luis Cuadrado Martin, Ana Claudia Kochi, Lidiane Silva Rodrigues-Telini, Pasqual Barretti, Jacqueline Teixeira Caramori, Beatriz Bojikian Matsubara, Silméia Garcia Zannati-Bazan, Roberto Jorge da Silva Franco and Thais Thomaz Queluz
    Citation: BMC Nephrology 2012 13:80
  43. ADPKD affects approximately 1:1000 of the worldwide population. It is caused by mutations in two genes, PKD1 and PKD2. Although allelic variation has some influence on disease severity, genic effects are strong, ...

    Authors: Caroline Robinson, Thomas F Hiemstra, Deborah Spencer, Sarah Waller, Laura Daboo, Fiona E Karet Frankl and Richard N Sandford
    Citation: BMC Nephrology 2012 13:79
  44. This study tests the hypotheses that health-related quality of life (HRQOL) in prevalent dialysis patients with diabetes is lower than in dialysis patients without diabetes, and is at least as poor as diabetic...

    Authors: Tone Britt Hortemo Østhus, Nanna von der Lippe, Lis Ribu, Tone Rustøen, Torbjørn Leivestad, Toril Dammen and Ingrid Os
    Citation: BMC Nephrology 2012 13:78
  45. The worldwide increasing trend of chronic kidney disease (CKD) is of great concern and the role of heart disease deserves longitudinal studies. This study investigated the risk of developing CKD among patients...

    Authors: Jiung-Hsiun Liu, Shih-Yi Lin, Chung-Yi Hsu, Hsin-Hung Lin, Chih-Chia Liang, Fung-Chang Sung and Chiu-Ching Huang
    Citation: BMC Nephrology 2012 13:77
  46. Elevated serum phosphorus (P) levels have been linked to increased morbidity and mortality in dialysis patients with secondary hyperparathyroidism (SHPT) but may be difficult to control if parathyroid hormone ...

    Authors: João M Frazão, Johann Braun, Piergiorgio Messa, Bastian Dehmel, Caroline Mattin and Martin Wilkie
    Citation: BMC Nephrology 2012 13:76
  47. The interleukin (IL)18 rs360719 CC genotype is associated with the development of antibodies to hepatitis B virus surface antigen (anti-HBs) in hemodialysis (HD) patients. IL18 shares biological properties with I...

    Authors: Alicja E Grzegorzewska, Piotr M Wobszal, Adrianna Mostowska and Paweł P Jagodziński
    Citation: BMC Nephrology 2012 13:75
  48. Systematic reviews comparing the effectiveness of strategies to prevent, detect, and treat chronic kidney disease are needed to inform patient care. We engaged stakeholders in the chronic kidney disease commun...

    Authors: Deidra C Crews, Raquel C Greer, Jeffrey J Fadrowski, Michael J Choi, David Doggett, Jodi B Segal, Kemi A Fawole, Pammie R Crawford and L Ebony Boulware
    Citation: BMC Nephrology 2012 13:74
  49. Fabry disease is an X-linked lysosomal storage disorder that results from a deficiency of the enzyme α-galactosidase A. Fabry disease is present in 4–5% of men with unexplained left ventricular hypertrophy or ...

    Authors: James O Burton, John P Dormer, Helen E Binns and Warren P Pickering
    Citation: BMC Nephrology 2012 13:73

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