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  1. Troponin T (TnT) is a well-known risk factor for negative outcome in hemodialysis (HD) patients, but little is known about variation over time, and the impact of clinical and dialysis specific factors. This st...

    Authors: Christian D. Peters, Krista D. Kjaergaard, Kent L. Christensen, Bo M. Bibby, Bente Jespersen and Jens D. Jensen

    Citation: BMC Nephrology 2020 21:452

    Content type: Research article

    Published on:

  2. Aging and mortality of patients on waiting lists for kidney transplantation have increased, as a result of the shortage of organs available all over the world. Living donor grafts represent a significant sourc...

    Authors: Rostand Emmanuel Nguefouet Momo, Paola Donato, Gabriele Ugolini, Francesco Nacchia, Luca Mezzetto, Gian Franco Veraldi, Stefano Marletta, Enrico Cavallo, Albino Eccher, Annamaria Giambanco, Daniela Cenzi and Luigino Boschiero

    Citation: BMC Nephrology 2020 21:451

    Content type: Case report

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  3. SLE manifestations after ESRD may be underdiagnosed and undertreated, contributing to increased morbidity and mortality. Whether specific symptoms persist after ESRD or a shift towards new manifestations occur...

    Authors: Maria Salgado Guerrero, Alejandra Londono Jimenez, Chrisanna Dobrowolski, Wenzhu B. Mowrey, Beatrice Goilav, Shudan Wang and Anna Broder

    Citation: BMC Nephrology 2020 21:450

    Content type: Research article

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  4. The pandemic of coronavirus disease 2019 (CoVID-19) has been an unprecedented period. The disease afflicts multiple organ systems, with acute kidney injury (AKI) a major complication in seriously ill patients....

    Authors: Sam Kant, Steven P. Menez, Mohamed Hanouneh, Derek M. Fine, Deidra C. Crews, Daniel C. Brennan, C. John Sperati and Bernard G. Jaar

    Citation: BMC Nephrology 2020 21:449

    Content type: Review

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  5. Patients on continuous ambulatory peritoneal dialysis (PD) are encouraged to warm dialysate to 37 °C before peritoneal infusion; main international PD guidelines do not provide specific recommendation, and pat...

    Authors: Francesco Fontana, Chiara Torelli, Silvia Giovanella, Giulia Ligabue, Gaetano Alfano, Karin Gerritsen, Rafael Selgas and Gianni Cappelli

    Citation: BMC Nephrology 2020 21:448

    Content type: Research article

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  6. Interstitial fibrosis/tubular atrophy (T) score is a known determinant of the progression of immunoglobulin A nephropathy (IgAN). Strong evidence indicates that the components of the coagulation system closely...

    Authors: Ming Xia, Di Liu, Liang Peng, Yan Li, Haiyang Liu, Lingzhi Wu, Guochun Chen, Yu Liu and Hong Liu

    Citation: BMC Nephrology 2020 21:447

    Content type: Research article

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  7. Acute kidney injury (AKI) is a known risk factor for chronic kidney disease (CKD) and end stage kidney disease (ESKD). The progression from AKI to CKD, despite being well recognised, is not completely understo...

    Authors: Anam Asad, James O. Burton and Daniel S. March

    Citation: BMC Nephrology 2020 21:446

    Content type: Review

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  8. Chronic kidney disease (CKD) is associated with poorer outcomes following percutaneous coronary intervention (PCI) with drug-eluting stents. Drug-eluting balloons are used for in-stent restenosis and selected ...

    Authors: Michael Jonas, Maayan Kagan, Gal Sella, Dan Haberman and Gil Chernin

    Citation: BMC Nephrology 2020 21:445

    Content type: Research article

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  9. Dyspepsia is a common disorder in kidney transplant recipients, and the risk of post-transplant complications is increased in candidates with upper gastrointestinal disease. We evaluated gastrointestinal lesio...

    Authors: Mehmet Usta, Alparslan Ersoy, Yavuz Ayar, Gökhan Ocakoğlu, Bilgehan Yuzbasioglu, Emrullah Düzgün Erdem and Omer Erdogan

    Citation: BMC Nephrology 2020 21:444

    Content type: Research article

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  10. Patients with end-stage kidney disease (ESKD) treated with hemodialysis (HD) experience many distressing symptoms. One frequently reported symptom is insomnia. There are unique issues about HD treatments and s...

    Authors: Mark Unruh, Daniel Cukor, Tessa Rue, Kashif Abad, Maria-Eleni Roumelioti, Susan M. McCurry, Patrick Heagerty and Rajnish Mehrotra

    Citation: BMC Nephrology 2020 21:443

    Content type: Study protocol

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  11. Although lupus nephritis (LN) is mostly characterized by glomerular involvement, tubular injury is indispensable in its pathogenesis and progression. The purpose of this study is to examine associations betwee...

    Authors: Huanhuan Zhu, Huiting Wan, Suyan Duan, Chengning Zhang, Qing Li, Simeng Liu, Lin Wu, Bo Zhang, Changying Xing and Yanggang Yuan

    Citation: BMC Nephrology 2020 21:442

    Content type: Research article

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  12. Early identification and treatment of kidney transplant rejection episodes is vital to limit loss of function and prolong the life of the transplanted kidney and recipient. Current practice depends on detectin...

    Authors: Amy Riddell, John Kirkwood, Miranda Smallwood, Paul Winyard, Beatrice Knight, Lidia Romanczuk, Angela Shore and Mark Gilchrist

    Citation: BMC Nephrology 2020 21:441

    Content type: Research article

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  13. HIV infection affects multiple organs and the kidney is a common target making renal disease, one of the recognized complications. Microalbuminuria represents an early, important marker of kidney damage in sev...

    Authors: Thomas Kiggundu, Robert Kalyesubula, Irene Andia-Biraro, Gyaviira Makanga and Pauline Byakika-Kibwika

    Citation: BMC Nephrology 2020 21:440

    Content type: Research article

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  14. Transplant renal artery stenosis (TRAS) is a serious vascular complication that occurs after renal transplantation and can result in hypertension, renal functional impairment, and graft loss. Endovascular trea...

    Authors: Xiangjun Dong, Yingliang Wang, Huimin Liang, Chuansheng Zheng, Hui Zhao, Hong yao Hu, Xi Long and Yangbo Su

    Citation: BMC Nephrology 2020 21:439

    Content type: Case report

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  15. Phase angle (PA), measured by bioelectrical impedance analysis (BIA) has been studied as indicator of nutritional status or muscle function in hemodialysis (HD) patients. It remains unclear if the phase angle ...

    Authors: Masakazu Saitoh, Masumi Ogawa, Hisae Kondo, Kiichi Suga, Tetsuya Takahashi, Haruki Itoh and Yoichiro Tabata

    Citation: BMC Nephrology 2020 21:438

    Content type: Research article

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  16. Peritoneal dialysis (PD) has been used occasionally in extremely-low-birth-weight (ELBW) infants with acute kidney injury (AKI). This study aimed to evaluate the clinical characteristics and outcomes of ELBW i...

    Authors: Jihyun Noh, Chae Young Kim, Euiseok Jung, Joo Hoon Lee, Young-Seo Park, Byong Sop Lee, Ellen Ai-Rhan Kim and Ki-Soo Kim

    Citation: BMC Nephrology 2020 21:437

    Content type: Research article

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  17. Individuals of African descent are at higher risk of developing kidney disease than their European counterparts, and HIV infection is associated with increased risk of nephropathy. Despite a safe renal profile...

    Authors: Muzamil O. Hassan, Raquel Duarte, Victor O. Mabayoje, Caroline Dickens, Akeem O. Lasisi and Saraladevi Naicker

    Citation: BMC Nephrology 2020 21:436

    Content type: Study protocol

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  18. PKHD1 is the main genetic cause of autosomal recessive polycystic kidney disease (ARPKD), a hereditary hepato-renal fibrocystic disorder which is the most important cause of end-stage renal disease during early c...

    Authors: Elisa Molinari, Shalabh Srivastava, Rebecca M. Dewhurst and John A. Sayer

    Citation: BMC Nephrology 2020 21:435

    Content type: Research article

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  19. Guillain-Barré syndrome (GBS) is an autoimmune polyneuropathy affecting the peripheral nervous system. This neurological disorder has been previously reported in bone marrow transplant recipients but is uncomm...

    Authors: Izabela Zakrocka, Iwona Baranowicz-Gąszczyk, Agnieszka Korolczuk and Wojciech Załuska

    Citation: BMC Nephrology 2020 21:434

    Content type: Case report

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  20. Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal.

    Authors: Kamal Ranabhat, Pratik Khanal, Shiva Raj Mishra, Anu Khanal, Sangita Tripathi and Mahesh Raj Sigdel

    Citation: BMC Nephrology 2020 21:433

    Content type: Research article

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  21. There is limited evidence on the association between short-term changes in mineral and bone disorder parameters and survival in maintenance hemodialysis patients.

    Authors: Chihiro Kato, Naohiko Fujii, Chisato Miyakoshi, Shinji Asada, Yoshihiro Onishi, Shingo Fukuma, Takanobu Nomura, Michihito Wada, Masafumi Fukagawa, Shunichi Fukuhara and Tadao Akizawa

    Citation: BMC Nephrology 2020 21:432

    Content type: Research article

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  22. Idiopathic membranous nephropathy (MN) is one of the major glomerulonephritis that cause nephrotic syndrome. The phospholipase A2 receptor (PLA2R) has recently been identified as an endogenous antigen of idiopath...

    Authors: Rei Iio, Shin’ichi Akiyama, Kensuke Mitsumoto, Yukimasa Iwata, Hiroki Okushima, Karin Shimada, Naomi Ota, Kodo Tomida, Hiroaki Fushimi, Tatsuya Shoji, Masanori Matsumoto and Terumasa Hayashi

    Citation: BMC Nephrology 2020 21:431

    Content type: Case report

    Published on:

  23. Medullary sponge kidney (MSK) is a rare disease characterized by cystic dilatation of papillary collecting ducts. Intravenous urography is still considered the gold standard for diagnosis. We identified a coho...

    Authors: Isabella Pisani, Roberto Giacosa, Sara Giuliotti, Dario Moretto, Giuseppe Regolisti, Chiara Cantarelli, Augusto Vaglio, Enrico Fiaccadori and Lucio Manenti

    Citation: BMC Nephrology 2020 21:430

    Content type: Research article

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  24. Anti-glomerular basement membrane disease (GBM) is an autoimmune disease caused by the deposition of circulating anti-GBM antibodies. Non-collagen region of α3 chain of type IV collagen (α3(IV)NC1) is one of t...

    Authors: Wen-jing Wang, Xiao-yu Jia, Zhao Cui, Yan Chen, Wei Wang, Jin-li Lou, Ming-hui Zhao and Sun Ying

    Citation: BMC Nephrology 2020 21:429

    Content type: Research article

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  26. Fluctuations in serum phosphate levels increased mortality in end-stage renal disease patients. However, the impacts of serum phosphate changes in hospitalized patients remain unclear. This study aimed to test...

    Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Panupong Hansrivijit, Sorkko Thirunavukkarasu, Api Chewcharat, Juan Medaura, Michael A. Mao and Kianoush B. Kashani

    Citation: BMC Nephrology 2020 21:427

    Content type: Research article

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  27. Bladder cancer is the most common malignant tumor of the urinary system. One of the biological characteristics of NMIBC is the high recurrence rate after surgery. The implementation of this project aimed to in...

    Authors: Zhenlong Wang, Hui Tang, Yuquan Xue, Li Xue, Hongliang Li and Tie Chong

    Citation: BMC Nephrology 2020 21:426

    Content type: Research article

    Published on:

  28. Chronic kidney disease has become a major health problem around the world. It displays no symptoms until the later stages. Therefore, its early detection is crucial, and a suitable intervention is necessary to...

    Authors: Haryati Anuar, Shamsul Azhar Shah, Abdul Halim Abdul Gafor and Mohd Ihsani Mahmood

    Citation: BMC Nephrology 2020 21:425

    Content type: Research article

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  29. Kidney disease accounts for more than 49 billion dollars in healthcare expenditures annually. Early detection and intervention may reduce the burden of disease. We describe a quality improvement project to dev...

    Authors: Melissa L. Swee, M. Lee Sanders, Kantima Phisitkul, George Bailey, Angie Thumann, Nikki Neuzil, Bharat Kumar, Amy M. J. O’Shea and Bradley S. Dixon

    Citation: BMC Nephrology 2020 21:424

    Content type: Research article

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  30. A series of policy changes in 2011 altered reimbursement arrangements and guidance on use of erythropoiesis-stimulating agents for end-stage renal disease (ESRD) patients with anaemia in the US. While the poli...

    Authors: Nga TQ. Nguyen, Alexander P. Maxwell, Michael Donnelly and Ciaran O’Neill

    Citation: BMC Nephrology 2020 21:423

    Content type: Research article

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  31. Early kidney transplantation (KT) is the best option for patients with end-stage kidney disease, but little is known about dialysis access strategy in this context. We studied practice patterns of dialysis acc...

    Authors: Raphaëlle Sylvestre, Natalia Alencar de Pinho, Ziad A. Massy, Christian Jacquelinet, Mathilde Prezelin-Reydit, Roula Galland, Bénédicte Stengel and Raphael Coscas

    Citation: BMC Nephrology 2020 21:422

    Content type: Research article

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  32. Patients with end-stage kidney disease, receiving haemodialysis rely increasingly on informal carers to help manage their debilitating chronic disease. Informal carers may experience a negative impact on their...

    Authors: Michael Matthews, Joanne Reid, Clare McKeaveney, Robert Mullan, Stephanie Bolton, Christopher Hill and Helen Noble

    Citation: BMC Nephrology 2020 21:421

    Content type: Study protocol

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  33. People with end-stage kidney disease have an increased risk of active tuberculosis (TB). Previous systematic reviews have demonstrated that patients with chronic kidney disease (CKD) have increased risk of sev...

    Authors: Judith Ruzangi, Masao Iwagami, Liam Smeeth, Punam Mangtani and Dorothea Nitsch

    Citation: BMC Nephrology 2020 21:420

    Content type: Research article

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  34. Infection with the severe acute respiratory coronavirus 2 (SARS-CoV-2) has led to a worldwide pandemic with coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2, overwhelming healthcare system...

    Authors: Samira Bell, Jacqueline Campbell, Jackie McDonald, Martin O’Neill, Chrissie Watters, Katharine Buck, Zoe Cousland, Mark Findlay, Nazir I. Lone, Wendy Metcalfe, Shona Methven, Robert Peel, Alison Almond, Vinod Sanu, Elaine Spalding, Peter C. Thomson…

    Citation: BMC Nephrology 2020 21:419

    Content type: Research article

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  35. The causes of anaemia in patients with end-stage renal disease include a relative deficiency in erythropoietin production and complex clinical conditions. We aimed to investigate the underlying mechanisms of a...

    Authors: Koichiro Matsumura, Toshika Okumiya, Tetsuro Sugiura, Nobuyuki Takahashi, Yoshihiro Yamamoto, Sanae Kikuchi, Kenichi Fujii, Munemitsu Otagaki and Ichiro Shiojima

    Citation: BMC Nephrology 2020 21:418

    Content type: Research article

    Published on:

  36. Acute kidney injury (AKI) is increasingly recognized as a consequential clinical complication in children with severe malaria. However, approaches to estimate baseline creatinine (bSCr) are not standardized in...

    Authors: Anthony Batte, Michelle C. Starr, Andrew L. Schwaderer, Robert O. Opoka, Ruth Namazzi, Erika S. Phelps Nishiguchi, John M. Ssenkusu, Chandy C. John and Andrea L. Conroy

    Citation: BMC Nephrology 2020 21:417

    Content type: Research article

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  37. Minimal change disease (MCD) is one of the causes of idiopathic nephrotic syndrome in adults. The pathogenesis of proteinuria in MCD has not been fully understood. Recently, it has been reported that the recep...

    Authors: Keisuke Horikoshi, Norihiko Sakai, Naoki Yamamoto, Hisayuki Ogura, Koichi Sato, Taro Miyagawa, Shinji Kitajima, Tadashi Toyama, Akinori Hara, Yasunori Iwata, Miho Shimizu, Kengo Furuichi and Takashi Wada

    Citation: BMC Nephrology 2020 21:416

    Content type: Case report

    Published on:

  38. Anaemia is a common presenting feature among patients with chronic kidney disease (CKD) and it is associated with poor clinical outcomes and quality of life. It is not clear if growth differentiation factor-15...

    Authors: Aishatu M. Nalado, Gbenga Olorunfemi, Therese Dix-Peek, Caroline Dickens, Lungile Khambule, Tracy Snyman, Graham Paget, Johnny Mahlangu, Raquel Duarte, Jaya George and Saraladevi Naicker

    Citation: BMC Nephrology 2020 21:415

    Content type: Research article

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  39. Chronic kidney disease (CKD) patients, especially those with end stage renal disease (ESRD) undergoing hemodialysis (HD), exhibit high prevalence of periodontitis. This cross-sectional study aimed to investiga...

    Authors: Xiaobo Duan, Xiaolei Chen, Megha Gupta, Dutmanee Seriwatanachai, Hanxiao Xue, Qiuchan Xiong, Tong Xu, Dan Li, Anchun Mo, Xi Tang, Xuedong Zhou, Yuqing Li and Quan Yuan

    Citation: BMC Nephrology 2020 21:414

    Content type: Research article

    Published on:

  40. Cardiovascular disease is the most common cause of death in patients with end-stage kidney disease on haemodialysis. The potential clinical consequence of systematic echocardiographic assessment is however not...

    Authors: Anna Axelsson Raja, Peder E. Warming, Ture L. Nielsen, Louis L. Plesner, Mads Ersbøll, Morten Dalsgaard, Morten Schou, Casper Rydahl, Lisbet Brandi and Kasper Iversen

    Citation: BMC Nephrology 2020 21:413

    Content type: Research article

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  41. Acute kidney injury (AKI) is defined as a sudden event of kidney failure or kidney damage within a short period. Ischemia-reperfusion injury (IRI) is a critical factor associated with severe AKI and end-stage ...

    Authors: Meeyoung Park, Chae Hwa Kwon, Hong Koo Ha, Miyeun Han and Sang Heon Song

    Citation: BMC Nephrology 2020 21(Suppl 1):398

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 1

  42. The optimal choice of treatment, with hemodialysis (HD) or peritoneal dialysis (PD), for end-stage renal disease (ESRD) patients, is still controversial. Only a few studies comparing HD and PD have been conduc...

    Authors: Zhiren He, Haijing Hou, Difei Zhang, Yenan Mo, La Zhang, Guobin Su, Junjie Lin, Liming Lu, Jingyao Huang, Yewen Gu, Ying Zhang, Jingxia Lin, Fengling Yuan, Yu Peng, Hui Liang, Daixin Zhao…

    Citation: BMC Nephrology 2020 21:412

    Content type: Research article

    Published on:

  43. Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in ...

    Authors: A. C. Nixon, T. J. Wilkinson, H.M.L. Young, M. W. Taal, N. Pendleton, S. Mitra, M. E. Brady, A. P. Dhaygude and A. C. Smith

    Citation: BMC Nephrology 2020 21:411

    Content type: Research article

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  44. Concurrent type 1 diabetes mellitus (T1DM) and idiopathic nephrotic syndrome is rare, and most previously reported cases were in children. We report the case of an adult woman who developed T1DM and minimal ch...

    Authors: Ryuzoh Nishizono, Hiroki Kogou, Yuri Ishizaki, Akihiro Minakawa, Masao Kikuchi, Hiroko Inagaki, Yuji Sato and Shouichi Fujimoto

    Citation: BMC Nephrology 2020 21:410

    Content type: Case report

    Published on:

  45. This scoping review sought to summarize available data on the prevalence, associated factors, etiology, comorbidities, treatment, cost and mortality of chronic kidney disease (CKD) in Cameroon.

    Authors: Jerry Brown Aseneh, Ben-Lawrence A. Kemah, Stephane Mabouna, Mbeng Emmanuel Njang, Domin Sone Majunda Ekane and Valirie Ndip Agbor

    Citation: BMC Nephrology 2020 21:409

    Content type: Review

    Published on:

  46. Autosomal dominant polycystic kidney disease (ADPKD), the predominant type of inherited kidney disorder, occurs due to PKD1 and PKD2 gene mutations. ADPKD diagnosis is made primarily by kidney imaging. However, m...

    Authors: Fatemeh Khadangi, Adam Torkamanzehi and Mohammad Amin Kerachian

    Citation: BMC Nephrology 2020 21:408

    Content type: Research article

    Published on:

  47. The epidemiology of dialysis patients has been little studied in developing countries and economies in transition. We examined the prevalence, incidence and mortality rate of dialysis patients in Kazakhstan, v...

    Authors: Abduzhappar Gaipov, Alpamys Issanov, Kainar Kadyrzhanuly, Dinara Galiyeva, Marina Khvan, Mohamad Aljofan, Miklos Z. Molnar and Csaba P. Kovesdy

    Citation: BMC Nephrology 2020 21:407

    Content type: Research article

    Published on:

  48. Herein, a 3-year-old boy presented with hidden-onset isolated proteinuria was reported. The disease was induced by COQ8B (previously termed ADCK4) compound heterozygous variants, including c.[271C > T] and c.[737...

    Authors: Shu-bo Zhai, Li Zhang, Bai-chao Sun, Yan Zhang and Qing-shan Ma

    Citation: BMC Nephrology 2020 21:406

    Content type: Case report

    Published on:

  49. We here report on the first observation of a C3 mutation that is related to atypical hemolytic and uremic syndrome (aHUS), which occurred in a pancreatic islet transplant patient. Immunosuppressive treatments,...

    Authors: Thibault Bahougne, Jérome Olagne, Marion Munch, Laura Braun-Parvez, Marie-Pierrette Chenard, Véronique Frémeaux-Bacchi, Sophie Caillard, Philippe Baltzinger, Michel Greget, Laurence Kessler and Bruno Moulin

    Citation: BMC Nephrology 2020 21:405

    Content type: Case report

    Published on:

  50. Calciphylaxis is a rare condition usually seen in patients with end-stage renal disease. Pain is a hallmark of this condition and can be extremely difficult to control. Anecdotal data suggests that pain manage...

    Authors: Rajkumar Chinnadurai, Smeeta Sinha, Aoife C Lowney and Mary Miller

    Citation: BMC Nephrology 2020 21:403

    Content type: Research article

    Published on:

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