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  1. Chronic kidney disease—mineral and bone disorders (CKD-MBD) is characterised by generalised vascular calcification (VC) and impaired bone health. We aimed to investigate the relationship between VC and bone mi...

    Authors: Jana Uhlinova, Anne Kuudeberg, Kaja Metsküla, Margus Lember and Mai Rosenberg
    Citation: BMC Nephrology 2022 23:327
  2. The Chinese Government initiated the Donation after Citizens' Death policy in 2010. To now, it has been a major source of organs for transplant. Since it is still a young policy, corresponding clinical evidenc...

    Authors: Xiao Fang, Yan Wang, Rong Liu, Changyan Zhu, Chenguang Wu, Fuqiang He, Shunliang Yang and Dong Wang
    Citation: BMC Nephrology 2022 23:325
  3. Chronic kidney disease (CKD) is a common complication after liver transplantation and is traditionally considered to be secondary to calcineurin inhibitors (CNIs). However, several studies have reported that t...

    Authors: Haijiao Jin, Yuehan Wei, Yongbing Qian, Jiang Zhang, Yao Xu, Hang Zhou, Minfang Zhang, Wenyan Zhou, Chaojun Qi, Wei Jin, Shan Mou, Qin Wang and Jianjun Zhang
    Citation: BMC Nephrology 2022 23:324
  4. Kidney stones have become a worldwide public health problem. The purpose of this research is to study the relationship between plasma cadmium level and the prevalence of kidney stones in an adult population.

    Authors: You Li, Kailian He, Liang Cao, Xu Tang, Ruoyu Gou, Tingyu Luo, Song Xiao, Ziqi Chen, Tingjun Li, Jian Qin, Zhiyong Zhang and Jiansheng Cai
    Citation: BMC Nephrology 2022 23:323
  5. Physical and emotional symptoms are prevalent in patients with kidney-dysfunction requiring dialysis (KDRD) and the rigors of thrice-weekly hemodialysis (HD) may contribute to deteriorated health-related quali...

    Authors: Mariana Murea, Benjamin R. Highland, Wesley Yang, Emily Dressler and Gregory B. Russell
    Citation: BMC Nephrology 2022 23:322
  6. Electronic health records can be used for population-wide identification and monitoring of disease. The Territory Kidney Care project developed algorithms to identify individuals with chronic kidney disease (C...

    Authors: Winnie Chen, Asanga Abeyaratne, Gillian Gorham, Pratish George, Vijay Karepalli, Dan Tran, Christopher Brock and Alan Cass
    Citation: BMC Nephrology 2022 23:320
  7. Sarcopenia is associated with various adverse outcomes in hemodialysis patients. However, current tools for assessing and diagnosing sarcopenia have limited applicability. In this study, we aimed to develop a ...

    Authors: Genlian Cai, Jinping Ying, Mengyan Pan, Xiabing lang, Weiping Yu and Qinqin Zhang
    Citation: BMC Nephrology 2022 23:319
  8. In centre haemodialysis (ICHD) patients have been identified as high risk of contracting Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection due to frequent healthcare contact and poor innat...

    Authors: Louise Rachel Moore, Noor Al-Jaddou, Harsha Wodeyar, Asheesh Sharma, Michael Schulz, Anirudh Rao and Kottarathil Abraham
    Citation: BMC Nephrology 2022 23:317
  9. The co-administration of loop diuretics with thiazide diuretics is a therapeutic strategy in patients with hypertension and volume overload. The aim of this study was to assess the efficacy and safety of treat...

    Authors: Fabio Solis-Jimenez, Lucia Monserrat Perez-Navarro, Ricardo Cabrera-Barron, Jesus Antonio Chida-Romero, Geovana Martin-Alemañy, Edgar Dehesa-López, Magdalena Madero and Rafael Valdez-Ortiz
    Citation: BMC Nephrology 2022 23:316
  10. Exercise and some pre-AKI diets have been shown to improve injury, apoptosis, and lipid profile. In this study, the effect of two different diets along with exercise training on acute kidney injury (AKI) was inve...

    Authors: Nazanin Sabet, Zahra Soltani, Mohammad Khaksari, Maryam Iranpour, Reza Malekpour Afshar, Fatemeh Mousavi Mehdiabadi and Alireza Raji-Amirhasani
    Citation: BMC Nephrology 2022 23:315
  11. Cholesterol crystal embolization syndrome (CES) occurs when an atherosclerotic plaque causes small-vessel embolization, resulting in multi-organ damage. Although CES is pathologically characterized by an infil...

    Authors: Tetsu Sakamoto, Takafumi Yamakawa, Keita Hirano, Arisa Kobayashi, Mio Kasai, Kiyoshi Koizumi, Takashi Yokoo, Satoru Komatsumoto, Toshimitsu Murohisa and Taro Shimizu
    Citation: BMC Nephrology 2022 23:314
  12. The M-type phospholipase A2 receptor (PLA2R)-associated idiopathic membranous nephropathy (IMN) is a common immune-related disease in adults. Vascular endothelial growth factor A (VEGFA) is the key mediator of...

    Authors: Ben Ke, Jinjing Huang, Zhibing Duan, Wen Shen, Yao Wu, Weiping Tu and Xiangdong Fang
    Citation: BMC Nephrology 2022 23:313
  13. Increased total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and decreased high-density lipoprotein cholesterol (HDL-C) concentrations, are established risk factors for ca...

    Authors: Misghina Weldegiorgis and Mark Woodward
    Citation: BMC Nephrology 2022 23:312

    The Correction to this article has been published in BMC Nephrology 2022 23:318

  14. Mechanisms by which AKI leads to CKD progression remain unclear. Several urine biomarkers have been identified as independent predictors of progressive CKD. It is unknown whether AKI may result in long-term ch...

    Authors: Ian E. McCoy, Jesse Y. Hsu, Joseph V. Bonventre, Chirag R. Parikh, Alan S. Go, Kathleen D. Liu, Ana C. Ricardo, Anand Srivastava, Debbie L. Cohen, Jiang He, Jing Chen, Panduranga S. Rao, Anthony N. Muiru and Chi-yuan Hsu
    Citation: BMC Nephrology 2022 23:311
  15. Performing percutaneous renal biopsy procedures in lupus nephritis (LN) and nephrotic syndrome presents a unique challenge to the nephrologist because of the risk of bleeding from the procedure and the hyperco...

    Authors: Muhammad Imran Kamarudin, Chandran Nadarajan and Mohamed Ashraf Mohamed Daud
    Citation: BMC Nephrology 2022 23:310
  16. Acute kidney injury (AKI) was common in the first two waves of the SARS-COV-2 pandemic in critically ill patients. A high percentage of these patients required renal replacement therapy and died in the hospital.

    Authors: Urmila Anandh, Amna Noorin, Syed Khurram Shehzad Kazmi, Sooraj Bannur, Syed Shahkar Ahmed Shah, Mehrin Farooq, Gopikrishna Yedlapati, Waseem Amer, Bonthu Prasad and Indranil Dasgupta
    Citation: BMC Nephrology 2022 23:308
  17. Plasma triglyceride (TG) levels are a significant risk factor for cardiovascular disease (CVD). The APOA5 gene is one of the crucial factors in plasma TG metabolism regulation. The rs662799 polymorphism in the AP...

    Authors: Jerry Jacob, Sylwia Boczkowska, Wojciech Zaluska and Monika Buraczynska
    Citation: BMC Nephrology 2022 23:307
  18. Idiopathic membranous nephropathy (iMN) is recognized as an organ-specific autoimmune disease, mainly caused by anti-PLA2R antibody. This study aimed to study between anti-PLA2R antibody level at diagnosis and...

    Authors: Bihua Wang, Zhidan Zhu, Feng Huang, Haowen Huang, Luxia Tu, Ying Wang, Linfeng Zheng, Jing Zhou and Xin Wei
    Citation: BMC Nephrology 2022 23:306

    The Correction to this article has been published in BMC Nephrology 2022 23:321

  19. Nephrotic syndrome (NS) is associated with increased risk of thromboembolic events (TE) adding to the morbidity and mortality. International guidelines recommend prophylactic anticoagulation in patients with N...

    Authors: Sarah Kelddal, Anne-Mette Hvas, Erik Lerkevang Grove and Henrik Birn
    Citation: BMC Nephrology 2022 23:305
  20. There is a growing literature on guidelines regarding Ramadan fasting for chronic kidney disease (CKD) patients. However, most studies only consider the impact of fasting on renal function. This study addition...

    Authors: Latifa Baynouna AlKetbi, Nico Nagelkerke, Amal AlZarouni, Mouza Al Kuwaiti, Mona Al Ghafli, Salama Al Qahtani, Bushra Al Kaabi, Mariam Al Kaabi, Ali Al Ahbabi, Yousif Al Zeyodi, Kholoud Al Ketheri, Khawla Al Nabooda, Khadija Al Tenaji, Ali AlAlawi and Hanan Abdelbaqi
    Citation: BMC Nephrology 2022 23:304
  21. Increasing evidence suggests that immune cell infiltration contributes to the pathogenesis and progression of diabetic nephropathy (DN). We aim to unveil the immune infiltration pattern in the glomerulus of DN...

    Authors: Wei ZHOU, Yaoyu LIU, Qinghong Hu, Jiuyao ZHOU and Hua LIN
    Citation: BMC Nephrology 2022 23:303
  22. Treatment burden refers to the work involved in managing one’s health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specif...

    Authors: Elizabeth C. Lorenz, Tanya M. Petterson, Isabella Zaniletti, Kandace A. Lackore, Bradley K. Johnson, Martin L. Mai, Sumi S. Nair, Andrew J. Bentall, Kathleen J. Yost and David T. Eton
    Citation: BMC Nephrology 2022 23:301
  23. Hemodialysis tunneled catheters are prone to failure due to infection or thrombosis. Prediction of catheter dysfunction chance and finding the predisposing risk factors might help clinicians to prolong proper ...

    Authors: Arash Mohazzab, Morteza Khavanin Zadeh, Paria Dehesh, Neda Abdolvand, Zhaleh Rahimi and Sahar Rahmani
    Citation: BMC Nephrology 2022 23:300
  24. Chronic kidney disease (CKD) is a recognized risk factor for severe complications in COVID-19. Our objective was to analyze the association between kidney function / T and B lymphocyte modulatory factors and r...

    Authors: Ladan Mansouri, Senka Sendic, Sebastian Havervall, Charlotte Thålin, Stefan H. Jacobson and Joachim Lundahl
    Citation: BMC Nephrology 2022 23:299
  25. Post-dialysis fatigue is a common and distressing complaint in patients on hemodialysis (HD). The dialysis recovery time (DRT) is a recent and reliable method of Post-dialysis fatigue assessment. We aimed to i...

    Authors: Mohamed Mamdouh Elsayed, Montasser Mohamed Zeid, Osama Mohamed Refai Hamza and Noha Mohamed Elkholy
    Citation: BMC Nephrology 2022 23:298
  26. The transport of water and urea through the erythrocyte membrane is facilitated by aquaporins such as aquaglyceroporin (AQP3), and type B urea transporters (UT-B). As they may play an important role in osmotic...

    Authors: Rafał Zwiech, Agnieszka Bruzda-Zwiech, Ewa Balcerczak, Joanna Szczepańska, Adrian Krygier, Beata Małachowska, Dominika Michałek and Dagmara Szmajda-Krygier
    Citation: BMC Nephrology 2022 23:297
  27. Endocapillary hypercellularity (ECHC) is commonly seen in class IV lupus nephritis (LN), the most common and severe LN in children. Factors influencing early complete remission (CR) in pediatric class IV LN ha...

    Authors: Chunzhen Li, Yanan Han, Lili Zhang, Zhiguo Chen, Mei Jin and Suzhen Sun
    Citation: BMC Nephrology 2022 23:296
  28. Anemia has been reported as a risk factor for chronic kidney disease (CKD) progression. However, there are still few studies examining the relationship between specific hemoglobin (Hb) levels and renal prognos...

    Authors: Wushan Pan, Yong Han, Haofei Hu and Yongcheng He
    Citation: BMC Nephrology 2022 23:295
  29. Acute kidney injury is a common complication in solid organ transplants, notably liver transplantation. The MELD is a score validated to predict mortality of cirrhotic patients, which is also used for organ al...

    Authors: Paulo Ricardo Gessolo Lins, Roberto Camargo Narciso, Leonardo Rolim Ferraz, Virgilio Gonçalves Pereira, Ben-Hur Ferraz-Neto, Marcio Dias De Almeida, Bento Fortunato Cardoso Dos Santos, Oscar Fernando Pavão Dos Santos, Júlio Cesar Martins Monte, Marcelino Souza Durão Júnior and Marcelo Costa Batista
    Citation: BMC Nephrology 2022 23:294
  30. The association between cardiac complications, such as heart failure (HF), and chronic kidney disease (CKD) is well known. In this study, we examined the effectiveness and safety of treatment with neprilysin i...

    Authors: María Dolores Martínez-Esteban, Teresa Vázquez-Sánchez, Rafael Pozo-Álvarez, Alicia Moreno-Ortiz, Juana Alonso-Titos, Guillermo Martín-Reyes, Pedro Ruiz-Esteban, Daniel Gaitán-Román and Domingo Hernández
    Citation: BMC Nephrology 2022 23:293
  31. Telehealth could potentially increase independency and autonomy of patients treated with peritoneal dialysis (PD). Moreover, it might improve clinical and economic outcomes. The demand for telehealth modalitie...

    Authors: Geertje K. M. Biebuyck, Aegida Neradova, Carola W. H. de Fijter and Lily Jakulj
    Citation: BMC Nephrology 2022 23:292
  32. Hyperphosphatemia occurs frequently in end-stage renal disease patients on hemodialysis and is associated with increased mortality. Hyperphosphatemia contributes to vascular calcification in these patients, bu...

    Authors: Jinwoo Jung, Haekyung Jeon-Slaughter, Hang Nguyen, Jiten Patel, Kamalanathan K. Sambandam, Shani Shastri and Peter Noel Van Buren
    Citation: BMC Nephrology 2022 23:291
  33. Tuberculosis (TBC) in solid organ transplant recipients represents a severe complication. The incidence among transplant recipients is higher than in the general population, and the diagnosis and treatment rem...

    Authors: Kamila Bednarova, Janka Slatinska, Ondrej Fabian, Pavel Wohl, Emilia Kopecka and Ondrej Viklicky
    Citation: BMC Nephrology 2022 23:290
  34. Restriction of sodium intake is routinely recommended for patients with chronic kidney disease (CKD). Whether or not sodium intake is associated with the progression of CKD and mortality remains uncertain. We ...

    Authors: Cecília Malheiro Cury, Vanessa Burgugi Banin, Pamela Falbo dos Reis, Jacqueline Costa Teixeira Caramori, Pasqual Barretti, Luís Gustavo Modelli de Andrade and Luis Cuadrado Martin
    Citation: BMC Nephrology 2022 23:289
  35. Glycated albumin (GA) is known to reflect the current inflammatory burden in non-diabetes mellitus (DM) patients. In this study, we investigated whether GA at diagnosis could reflect the cross-sectional activi...

    Authors: Pil Gyu Park, Jung Yoon Pyo, Sung Soo Ahn, Jason Jungsik Song, Yong-Beom Park and Sang-Won Lee
    Citation: BMC Nephrology 2022 23:288
  36. The electronic health record (EHR), utilized to apply statistical methodology, assists provider decision-making, including during the care of chronic kidney disease (CKD) patients. When estimated glomerular fi...

    Authors: Reyhaneh Zafarnejad, Steven Dumbauld, Diane Dumbauld, Mohammad Adibuzzaman, Paul Griffin and Edwin Rutsky
    Citation: BMC Nephrology 2022 23:287
  37. In chronic kidney disease (CKD), like in IgA nephropathy (IgAN), cardiovascular (CV) mortality and morbidity are many times higher than in the general population, and left ventricular hypertrophy (LVH) is an i...

    Authors: Balázs Sági, István Késői, Tibor Vas, Botond Csiky, Judit Nagy and Tibor József Kovács
    Citation: BMC Nephrology 2022 23:285
  38. Kidney transplantation is an effective treatment for end-stage renal disease (ESRD). Delayed graft function (DGF) is a common complication after kidney transplantation and exerts substantial effects on graft f...

    Authors: Shitao Zhao, Yuan Liu, Chen Zhou, Zide Chen, Zeyu Cai, JiaLiang Han, Jiansheng Xiao and Qi Xiao
    Citation: BMC Nephrology 2022 23:284
  39. Kidney transplantation in older people has increased, however older transplant recipients experience mixed outcomes that invariably impacts on their quality of life. The increased vulnerability of older end st...

    Authors: Amarpreet K. Thind, Annabel Rule, Dawn Goodall, Shuli Levy, Sarah Brice, Frank J. M. F. Dor, Nicola Evans, David Ospalla, Nicola Thomas, David Wellsted, Lina Johansson, Michelle Willicombe and Edwina A. Brown
    Citation: BMC Nephrology 2022 23:283
  40. Community engagement is essential for effective research when addressing issues important to both the community and researchers. Despite its effectiveness, there is limited published evidence concerning the ev...

    Authors: Angie Aguilar-González, Randall Lou-Meda, André Chocó-Cedillos and Louise Moist
    Citation: BMC Nephrology 2022 23:282
  41. Hyperkalaemia is common in patients with chronic kidney disease (CKD) and is associated with a range of adverse outcomes. Historically, options for management of chronic hyperkalaemia in the outpatient setting...

    Authors: Kun Kim, Josefine Fagerström, Gengshi Chen, Zoya Lagunova, Hans Furuland and Phil McEwan
    Citation: BMC Nephrology 2022 23:281
  42. Many individuals living with chronic kidney disease (CKD) have comorbid Type 2 diabetes (T2D). We sought to explore if efficacious interventions that improve glycemic control may also have potential to reduce ...

    Authors: McKenzie K. Roddy, Lindsay S. Mayberry, Devika Nair and Kerri L. Cavanaugh
    Citation: BMC Nephrology 2022 23:280
  43. The first case of Taralomyces flavus infection in human and peritoneal dialysis (PD) patient after exposure to biocontrol agent fumes is reported here.

    Authors: Phanit Sookto, Talerngsak Kanjanabuch, Tamonwan Chamroensakchai, Nisa Thongbor and Somchai Eiam-Ong
    Citation: BMC Nephrology 2022 23:279
  44. Monoclonal gammopathy of renal significance (MGRS) encompasses a heterogeneous group of kidney diseases in which a monoclonal immunoglobulin secreted by a clone of B cells or plasma cells causes kidney damage ...

    Authors: Gabriel Brayan Gutiérrez-Peredo, José César Batista Oliveira Filho, Iris Montaño-Castellón, Andrea Jimena Gutiérrez-Peredo, Edvan de Queiroz Crusoé and Dimitri Gusmao-Flores
    Citation: BMC Nephrology 2022 23:278
  45. The number of chronic kidney disease (CKD) patients continues to increase worldwide. CKD patients need to take phosphate binders to manage serum phosphorus concentrations. Currently, several types of phosphate...

    Authors: Akiko Hashimoto, Jiaqi Gao, Yuki Kanome, Yukihiro Ogawa, Masaharu Nakatsu, Masahiro Kohno and Koji Fukui
    Citation: BMC Nephrology 2022 23:277

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