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  1. Schimke immuno-osseous dysplasia (SIOD, OMIM #242900) is an autosomal-recessive pleiotropic disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction and T-cell immunodeficiency. SIOD is caused...

    Authors: Luisa Santangelo, Maddalena Gigante, Giuseppe Stefano Netti, Sterpeta Diella, Flora Puteo, Vincenza Carbone, Giuseppe Grandaliano, Mario Giordano and Loreto Gesualdo
    Citation: BMC Nephrology 2014 15:41
  2. Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one’s residence to dialysis centre a...

    Authors: Lisa M Miller, Lavern M Vercaigne, Louise Moist, Charmaine E Lok, Navdeep Tangri, Paul Komenda, Claudio Rigatto, Julie Mojica and Manish M Sood
    Citation: BMC Nephrology 2014 15:40
  3. An analysis of intracranial hemorrhage (ICH) in a national sample of autosomal dominant polycystic kidney disease (ADPKD) patients receiving long-term dialysis has not been reported. It is often assumed that p...

    Authors: David J Yoo, Lawrence Agodoa, Christina M Yuan, Kevin C Abbott and Robert Nee
    Citation: BMC Nephrology 2014 15:39
  4. Home-based dialysis, including peritoneal dialysis (PD) and home hemodialysis (HHD), is associated with improved health related quality of life and reduced health resource costs. It is uncertain to what extent...

    Authors: Patrick T Keating, Michael Walsh, Christine M Ribic and Kenneth Scott Brimble
    Citation: BMC Nephrology 2014 15:38
  5. About 1% of patients admitted to the Emergency Department (ED) have hypernatremia, a condition associated with a mortality rate of 20 to 60%. Management recommendations originate from intensive care unit studi...

    Authors: Stanislas Bataille, Camille Baralla, Dominique Torro, Christophe Buffat, Yvon Berland, Marc Alazia, Anderson Loundou, Pierre Michelet and Henri Vacher-Coponat
    Citation: BMC Nephrology 2014 15:37
  6. The prevalence of chronic kidney disease (CKD) and metabolic diseases has increased at different rates in different regions in China. The aim of our study was to estimate the prevalence of CKD and to analyze a...

    Authors: Bo Lin, Lina Shao, Qun Luo, Lingxia Ou-yang, Fangfang Zhou, Biao Du, Qiang He, Jianyong Wu, Nan Xu and Jianghua Chen
    Citation: BMC Nephrology 2014 15:36
  7. Peritoneal dialysis (PD) therapy is known to induce morphological and functional changes in the peritoneal membrane. Long-term exposure to conventional bio-incompatible dialysate and peritonitis is the main et...

    Authors: Yi-Che Lee, Yau-Sheng Tsai, Shih-Yuan Hung, Tsun-Mei Lin, Sheng-Hsiang Lin, Hung-Hsiang Liou, Hsiang-Chun Liu, Min-Yu Chang, Hsi-Hao Wang, Li-Chun Ho, Yi-Ting Chen, Hsin-Pao Chen, Hong-Arh Fan, Kuang-Wen Liu, Yung-Tang Kung, Hao-Kuang Wang…
    Citation: BMC Nephrology 2014 15:35
  8. There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5.

    Authors: Veronica M Swallow, Andrew G Hall, Ian Carolan, Sheila Santacroce, Nicholas JA Webb, Trish Smith and Noreen Hanif
    Citation: BMC Nephrology 2014 15:34
  9. Home-based renal replacement therapy (RRT) [peritoneal dialysis (PD) and home hemodialysis (HHD)] offers independent quality of life and clinical advantages compared to conventional in-center hemodialysis. How...

    Authors: Michael E Schachter, Joanne M Bargman, Michael Copland, Michelle Hladunewich, Karthik K Tennankore, Adeera Levin, Matthew Oliver, Robert P Pauly, Jeffrey Perl, Deborah Zimmerman and Christopher T Chan
    Citation: BMC Nephrology 2014 15:33
  10. Podocytic infolding glomerulopathy (PIG) is a recently described condition causing rare pathological changes to the glomeruli, and has attracted considerable attention. PIG is characterized by specific changes...

    Authors: Makoto Harada, Yuji Kamijo, Takashi Ehara, Hisashi Shimojo, Hidekazu Shigematsu and Makoto Higuchi
    Citation: BMC Nephrology 2014 15:32
  11. The major challenge in ABO-incompatible transplantation is to minimize antibody-mediated rejection. Effective reduction of the anti-ABO blood group antibodies at the time of transplantation has made ABO-incomp...

    Authors: Annelies de Weerd, Alieke Vonk, Hans van der Hoek, Marian van Groningen, Willem Weimar, Michiel Betjes and Madelon van Agteren
    Citation: BMC Nephrology 2014 15:31
  12. The choice of vascular access type is an important aspect of care for incident hemodialysis patients. However, data from the Centers for Medicare & Medicaid Services (CMS) Medical Evidence Report (form CMS-272...

    Authors: Craig A Solid, Allan J Collins, James P Ebben, Shu-Cheng Chen, Arman Faravardeh, Robert N Foley and Areef Ishani
    Citation: BMC Nephrology 2014 15:30
  13. Many patients on maintenance dialysis experience significant sleepiness and fatigue. However, the influence of the hemodialysis (HD) day and circadian rhythms on patients’ symptoms have not been well character...

    Authors: Khaled Abdel-Kader, Manisha Jhamb, Lee Anne Mandich, Jonathan Yabes, Robert M Keene, Scott Beach, Daniel J Buysse and Mark L Unruh
    Citation: BMC Nephrology 2014 15:29
  14. We report a case of progressive Granulomatosis with Polyangiitis (Wegener’s Granulomatosis) with life-threatening complications of both the underlying disease and induction immunosuppressive therapy. Here, for...

    Authors: Elena Ernst, Matthias Girndt and Rainer U Pliquett
    Citation: BMC Nephrology 2014 15:28
  15. Activated vitamin D is the mainstay of treatment for secondary hyperparathyroidism (SHPT) in chronic hemodialysis patients. However, the optimal route of administration is still debated. The aim of our study w...

    Authors: Myriam Lessard, Denis Ouimet, Martine Leblanc, Annie-Claire Nadeau-Fredette, Robert Bell, Jean-Philippe Lafrance, Vincent Pichette and Michel Vallée
    Citation: BMC Nephrology 2014 15:27
  16. While fluid overload (FO) and alterations in the autonomic nervous system (ANS) such as hypersympathetic activity, are known risk factors for cardiovascular morbidity and mortality in patients on chronic hemod...

    Authors: Manuela Ferrario, Ulrich Moissl, Francesco Garzotto, Dinna N Cruz, Anna Clementi, Alessandra Brendolan, Ciro Tetta, Emanuele Gatti, Maria G Signorini, Sergio Cerutti and Claudio Ronco
    Citation: BMC Nephrology 2014 15:26
  17. Children and adolescents with end-stage renal disease (ESRD) in sub-Saharan Africa may have the worst outcomes globally. Barriers to management include late presentation, poor socioeconomic conditions, absence...

    Authors: Adanze O Asinobi, Adebowale D Ademola, Oluwatoyin O Ogunkunle and Susan A Mott
    Citation: BMC Nephrology 2014 15:25
  18. The human glomerulus is the primary filtration unit of the kidney, and contains the Glomerular Filtration Barrier (GFB). The GFB had been thought to comprise 3 layers - the endothelium, the basement membrane a...

    Authors: Kenton P Arkill, Klaus Qvortrup, Tobias Starborg, Judith M Mantell, Carlo Knupp, C Charles Michel, Steve J Harper, Andy HJ Salmon, John M Squire, Dave O Bates and Chris R Neal
    Citation: BMC Nephrology 2014 15:24
  19. Measurement of renal perfusion is a crucial part of measuring kidney function. Arterial spin labelling magnetic resonance imaging (ASL MRI) is a non-invasive method of measuring renal perfusion using magnetise...

    Authors: Keith A Gillis, Christie McComb, John E Foster, Alison HM Taylor, Rajan K Patel, Scott TW Morris, Alan G Jardine, Markus P Schneider, Giles H Roditi, Christian Delles and Patrick B Mark
    Citation: BMC Nephrology 2014 15:23
  20. The inflammasome is a large, multiprotein complex that drives proinflammatory cytokine production in response to infection and tissue injury. Pattern recognition receptors that are either membrane bound or cyt...

    Authors: Clare M Turner, Nishkantha Arulkumaran, Mervyn Singer, Robert J Unwin and Frederick WK Tam
    Citation: BMC Nephrology 2014 15:21
  21. The natural history of patients commencing dialysis in East Yorkshire is not well characterised and there is little convincing evidence which has studied the impact of potential factors prior to commencement o...

    Authors: Oliver T Browne, Victoria Allgar and Sunil Bhandari
    Citation: BMC Nephrology 2014 15:20
  22. During continuous venovenous haemofiltration (CVVH), regional anticoagulation with citrate may be superior to heparin in terms of biocompatibility, since heparin as opposed to citrate may activate complement (...

    Authors: Louise Schilder, S Azam Nurmohamed, Pieter M ter Wee, Nanne J Paauw, Armand RJ Girbes, Albertus Beishuizen, Robert HJ Beelen and AB Johan Groeneveld
    Citation: BMC Nephrology 2014 15:19
  23. Many markers have been proposed for CVD risk assessment in dialysis population. Apelin is a peptide that has roles in cardiovascular functions and volume regulation namely vasodilation, decreased blood pressur...

    Authors: Serhat Karadag, Savas Ozturk, Meltem Gursu, Ahmet Gurdal, Filiz Basinoglu, Servet Yigit, Zeki Aydin, Sami Uzun, Abdullah Sumnu, Huseyin Oflaz and Rumeyza Kazancioglu
    Citation: BMC Nephrology 2014 15:18
  24. Malnutrition is associated with an increased risk of cardiovascular death and may cause protein-energy wasting in individuals with chronic kidney disease. A previous study demonstrated that blood cadmium level...

    Authors: Ching-Wei Hsu, Ja-Liang Lin, Dan-Tzu Lin-Tan, Wen-Hung Huang, Kuan-Hsing Chen and Tzung-Hai Yen
    Citation: BMC Nephrology 2014 15:17
  25. Structured comparison of pharmacoeconomic analyses for ACEIs and ARBs in patients with type 2 diabetic nephropathy is still lacking. This review aims to systematically review the cost-effectiveness of both ACE...

    Authors: Yunyu Huang, Qiyun Zhou, Flora M Haaijer-Ruskamp and Maarten J Postma
    Citation: BMC Nephrology 2014 15:15
  26. Recent studies in animal models have shown that statins can protect against renal failure independent of their lipid-lowering actions, and there is also an association between statin use and improved renal fun...

    Authors: Kefei Wu, Wenjing Lei, Jianwei Tian and Hongyan Li
    Citation: BMC Nephrology 2014 15:14
  27. Uncertainty exists regarding the optimal method to estimate glomerular filtration rate (GFR) for disease detection and monitoring. Widely used GFR estimates have not been validated in British ethnic minority p...

    Authors: Edmund J Lamb, Elizabeth A Brettell, Paul Cockwell, Neil Dalton, Jon J Deeks, Kevin Harris, Tracy Higgins, Philip A Kalra, Kamlesh Khunti, Fiona Loud, Ryan S Ottridge, Claire C Sharpe, Alice J Sitch, Paul E Stevens, Andrew J Sutton and Maarten W Taal
    Citation: BMC Nephrology 2014 15:13
  28. The presence of glutathione transferase (GST) M1 null genotype (GSTM1-null) in end-stage renal disease (ESRD) patients is associated with lower overall survival rate in comparison to those with GSTM1-active varia...

    Authors: Sonja Suvakov, Tatjana Damjanovic, Tatjana Pekmezovic, Jovana Jakovljevic, Ana Savic-Radojevic, Marija Pljesa-Ercegovac, Slavica Radovanovic, Dragan V Simic, Steva Pljesa, Milos Zarkovic, Jasmina Mimic-Oka, Nada Dimkovic and Tatjana Simic
    Citation: BMC Nephrology 2014 15:12
  29. Hyperuricemia appeared to be a common symptom in IgA nephropathy (IgAN), even in those with normal eGFR. IgAN was characterized by variation of pathological features, especially variable tubulointerstitial les...

    Authors: Jingjing Zhou, Yuqing Chen, Ying Liu, Sufang Shi, Xueying Li, Suxia Wang and Hong Zhang
    Citation: BMC Nephrology 2014 15:11
  30. Posterior reversible encephalopathy syndrome (PRES) is a clinical and radiological entity characterized clinically by headache, altered mental status, seizures, visual disturbances, and other focal neurologica...

    Authors: Brett R Graham and George B Pylypchuk
    Citation: BMC Nephrology 2014 15:10
  31. Detecting impaired glomerular filtration rate (GFR) is important in intensive care units (ICU) in order to diagnose acute kidney injuries and adjust the dose of renally excreted drugs. Whether serum Cystatin C...

    Authors: Pierre Delanaye, Etienne Cavalier, Jérôme Morel, Manolie Mehdi, Nicolas Maillard, Guillaume Claisse, Bernard Lambermont, Bernard E Dubois, Pierre Damas, Jean-Marie Krzesinski, Alexandre Lautrette and Christophe Mariat
    Citation: BMC Nephrology 2014 15:9
  32. Repeated exposure to peritoneal dialysis (PD) solutions contributes to cumulative intraperitoneal inflammation and peritoneal injury. The present study aimed to explore the capacity of dialysate interleukin-6(...

    Authors: Yeoungjee Cho, David W Johnson, David A Vesey, Carmel M Hawley, Elaine M Pascoe, Margaret Clarke and Nicholas Topley
    Citation: BMC Nephrology 2014 15:8
  33. Chronic musculoskeletal (MS) pain is common in patients with chronic kidney disease (CKD) undergoing haemodialysis. However, epidemiological data for chronic MS pain and factors associated with chronic MS pain...

    Authors: Heng-Jung Hsu, Chiung-Hui Yen, Kuang-Hung Hsu, I-Wen Wu, Chin-Chan Lee, Ming-Jui Hung, Chiao-Yin Sun, Chia-Chi Chou, Yung-Chih Chen, Ming-Fang Hsieh, Chun-Yu Chen, Chiao-Ying Hsu, Chi-Jen Tsai and Mai-Szu Wu
    Citation: BMC Nephrology 2014 15:6
  34. Haemolytic-uremic syndrome (HUS) is a severe, life-threatening disease with symptoms such as haemolytic anaemia, renal failure, and a low platelet count. Possible aetiology includes bacterial infections, medic...

    Authors: Yi-Che Lee, Jyh-Seng Wang, Jeng-Chuan Shiang, Ming-Kai Tsai, Kai-Tai Deng, Min-Yu Chang, Hsi-Hao Wang, Li-Chun Ho, Yi-Ting Chen and Shih-Yuan Hung
    Citation: BMC Nephrology 2014 15:5
  35. Little is known about the effects of intermittent hemodialysis on microcirculatory perfusion. The aim of this study is to assess the effects of hemodialysis on microvascular perfusion using transcutaneous oxym...

    Authors: Ygal Benhamou, Loic Begarin, Nathalie David, Nicole Cailleux, Catherine Bessin, Herve Lévesque and Stephane Edet
    Citation: BMC Nephrology 2014 15:4
  36. Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure ...

    Authors: Marijan Saraga, Katarina Vukojević, Vjekoslav Krželj, Zvonimir Puretić, Ivana Bočina, Merica Glavina Durdov, Stefanie Weber, Bernd Dworniczak, Danica Galešić Ljubanović and Mirna Saraga-Babić
    Citation: BMC Nephrology 2014 15:3
  37. Contrast-induced nephropathy (CIN) is a common cause of acute renal failure in hospital patients. To prevent CIN, identification and hydration of high-risk patients is important. Prevention of CIN by hydration...

    Authors: Janneke Schilp, Carolien de Blok, Maaike Langelaan, Peter Spreeuwenberg and Cordula Wagner
    Citation: BMC Nephrology 2014 15:2
  38. Acute kidney injury in patients with acute pancreatitis carries a poor prognosis. Hemolytic uremic syndrome (HUS) is characterized by non-immune hemolytic anemia, thrombocytopenia, and renal failure caused by ...

    Authors: Peng Fu, Ai-hong Yuan, Chun-hua Wang, Xin Li and Hai-yang Wu
    Citation: BMC Nephrology 2014 15:1
  39. High iron load might have a number of toxic effects in the organism. Recently intravenous (iv) iron has been proposed to induce elevation of fibroblast growth factor 23 (FGF23), hypophosphatemia and osteomalac...

    Authors: Eva Gravesen, Jacob Hofman-Bang, Maria L Mace, Ewa Lewin and Klaus Olgaard
    Citation: BMC Nephrology 2013 14:281
  40. Cardiovascular disease is a major cause of death in patients with stage 4–5 Chronic Kidney disease (CKD, eGFR < 30). There are only limited data on the risk factors predicting these complications in CKD patien...

    Authors: Ahmad Farshid, Rajeev Pathak, Bruce Shadbolt, Leonard Arnolda and Girish Talaulikar
    Citation: BMC Nephrology 2013 14:280
  41. The Camp COOL programme aims to help young Dutch people with end-stage renal disease (ESRD) develop self-management skills. Fellow patients already treated in adult care (hereafter referred to as ‘buddies’) or...

    Authors: Jane NT Sattoe, Susan Jedeloo and AnneLoes van Staa
    Citation: BMC Nephrology 2013 14:279
  42. Australians living in rural areas have lower incidence rates of renal replacement therapy and poorer dialysis survival compared with urban dwellers. This study compares peritoneal dialysis (PD) patient charact...

    Authors: Nicholas A Gray, Blair S Grace and Stephen P McDonald
    Citation: BMC Nephrology 2013 14:278
  43. Anti-glomerular basement membrane (GBM) glomerulonephritis and systemic lupus erythematosus (SLE) are both disorders of the immune system; however, they are known as distinct diseases. Till now no clinical evi...

    Authors: Xiaoxia Liu, Yu Wu, Yuan Yang, Jue Wang, Ye Tao, Ping Fu and Zhangxue Hu
    Citation: BMC Nephrology 2013 14:277
  44. Hyponatremia is associated with increased mortality in chronic kidney disease with and without end-stage renal disease (ESRD). Increasing evidence suggests that hyponatremia is not only a marker of severe unde...

    Authors: Shintaro Mandai, Michio Kuwahara, Yuri Kasagi, Keita Kusaka, Tomomi Tanaka, Satomi Shikuma, Wataru Akita and Sei Sasaki
    Citation: BMC Nephrology 2013 14:276
  45. Dyspepsia is common among end-stage renal disease (ESRD) patients and its association with delayed gastric emptying is not well established. We assessed the association of dyspepsia with gastric emptying time ...

    Authors: Luiz Derwal Salles Junior, Paulo Roberto Santos, Armênio Aguiar dos Santos and Marcellus Henrique Loiola Ponte de Souza
    Citation: BMC Nephrology 2013 14:275
  46. Dendritic cells (DC) are professional antigen-presenting cells in the immune system. They patrol the blood as circulating dendritic cell precursors (DCP). Decreased blood DCP count has been shown to be related...

    Authors: Katharina Paul, Daniel Kretzschmar, Atilla Yilmaz, Barbara Bärthlein, Stephanie Titze, Gunter Wolf and Martin Busch
    Citation: BMC Nephrology 2013 14:274
  47. The predictive value of acute kidney injury (AKI) urinary biomarkers may depend on the time interval following tubular injury, thereby explaining in part the heterogeneous performance of these markers that has...

    Authors: Hilde RH de Geus, Gijs Fortrie, Michiel GH Betjes, Ron HN van Schaik and AB Johan Groeneveld
    Citation: BMC Nephrology 2013 14:273

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